ATE219676T1 - Verfahren zum abtöten neoplastischer zellen mittels piperazin-oxiran derivaten - Google Patents
Verfahren zum abtöten neoplastischer zellen mittels piperazin-oxiran derivatenInfo
- Publication number
- ATE219676T1 ATE219676T1 AT97903981T AT97903981T ATE219676T1 AT E219676 T1 ATE219676 T1 AT E219676T1 AT 97903981 T AT97903981 T AT 97903981T AT 97903981 T AT97903981 T AT 97903981T AT E219676 T1 ATE219676 T1 AT E219676T1
- Authority
- AT
- Austria
- Prior art keywords
- piperazine
- neoplastic cells
- oxirane derivatives
- killing neoplastic
- killing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/592,540 US5733911A (en) | 1996-01-26 | 1996-01-26 | Method for inducing death of neoplastic cells using piperazne derivatives |
| PCT/US1997/001231 WO1997026881A1 (en) | 1996-01-26 | 1997-01-24 | Method for inducing death of neoplastic cells using piperazine oxirane derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE219676T1 true ATE219676T1 (de) | 2002-07-15 |
Family
ID=24371096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97903981T ATE219676T1 (de) | 1996-01-26 | 1997-01-24 | Verfahren zum abtöten neoplastischer zellen mittels piperazin-oxiran derivaten |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US5733911A (de) |
| EP (1) | EP0877614B1 (de) |
| JP (1) | JP4117404B2 (de) |
| KR (1) | KR100468271B1 (de) |
| CN (1) | CN1220490C (de) |
| AR (1) | AR005569A1 (de) |
| AT (1) | ATE219676T1 (de) |
| AU (1) | AU731125B2 (de) |
| CA (1) | CA2242657A1 (de) |
| DE (1) | DE69713570T2 (de) |
| ID (1) | ID18975A (de) |
| TW (1) | TW475897B (de) |
| WO (1) | WO1997026881A1 (de) |
| ZA (1) | ZA97676B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU716620B2 (en) * | 1995-03-31 | 2000-03-02 | Nippon Chemiphar Co. Ltd. | Epoxysuccinic acid derivatives |
| US5733911A (en) * | 1996-01-26 | 1998-03-31 | Hitachi Chemical Co., Ltd. | Method for inducing death of neoplastic cells using piperazne derivatives |
| DK1022276T3 (da) * | 1997-09-04 | 2003-09-29 | Nippon Chemiphar Co | Epoxysuccinamidderivater |
| EP1094063A1 (de) * | 1999-10-18 | 2001-04-25 | Applied Research Systems ARS Holding N.V. | 9-(Piperazinylalkyl)carbazole als Bax-Modulatoren |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US6376514B1 (en) | 2000-10-17 | 2002-04-23 | The Procter & Gamble Co. | Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof |
| EP1798217A1 (de) * | 2000-10-23 | 2007-06-20 | Arizona Biomedical Research Commission | Krebsmittel auf Basis der Regulierung der Proteinprenylierung |
| AU2002221261A1 (en) * | 2001-11-22 | 2003-06-10 | Mehmet Ozturk | Method, antigen and antibody for distinguishing viable and apoptotic cells |
| CN112472699A (zh) | 2013-07-26 | 2021-03-12 | 种族肿瘤学公司 | 改善比生群及衍生物的治疗益处的组合方法 |
| PL407922A1 (pl) * | 2014-04-16 | 2015-10-26 | Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością | Nowe bisfosfoniany i ich zastosowanie |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55115878A (en) * | 1979-02-27 | 1980-09-06 | Taisho Pharmaceut Co Ltd | Epoxysuccinic acid derivative |
| JPS55153778A (en) * | 1979-05-17 | 1980-11-29 | Taisho Pharmaceut Co Ltd | Epoxysuccinylamino acid derivative |
| US4474800A (en) * | 1980-05-13 | 1984-10-02 | Taisho Pharmaceutical Co., Ltd. | Epoxysuccinyl amino acid derivatives |
| JPS57169478A (en) * | 1981-04-10 | 1982-10-19 | Nippon Chemiphar Co Ltd | Piperazine derivative |
| JPS6276A (ja) * | 1985-03-26 | 1987-01-06 | Toyo Jozo Co Ltd | 酵素阻害性新規物質 |
| JPH0832698B2 (ja) * | 1987-05-08 | 1996-03-29 | 日本ケミファ株式会社 | ピペラジン誘導体 |
| US5214056A (en) * | 1989-12-27 | 1993-05-25 | Japan Tobacco Inc. | 1,3,2-dioxathiolane oxide derivative |
| WO1993006143A1 (fr) * | 1991-09-19 | 1993-04-01 | Cray Valley Sa | Resines de petrole thermiquement stables, leur procede de preparation et leur application a la formulation d'adhesifs thermofusibles |
| JPH0641067A (ja) * | 1992-04-20 | 1994-02-15 | Kitasato Inst:The | 新規カルパイン阻害物質ｋｐ−１２４１及びその製造法 |
| ATE171171T1 (de) * | 1992-12-25 | 1998-10-15 | Mitsubishi Chem Corp | Alpha-aminoketon derivate |
| US5733911A (en) * | 1996-01-26 | 1998-03-31 | Hitachi Chemical Co., Ltd. | Method for inducing death of neoplastic cells using piperazne derivatives |
-
1996
- 1996-01-26 US US08/592,540 patent/US5733911A/en not_active Expired - Fee Related
-
1997
- 1997-01-24 JP JP52706097A patent/JP4117404B2/ja not_active Expired - Fee Related
- 1997-01-24 CA CA002242657A patent/CA2242657A1/en not_active Abandoned
- 1997-01-24 KR KR10-1998-0705786A patent/KR100468271B1/ko not_active IP Right Cessation
- 1997-01-24 AU AU18402/97A patent/AU731125B2/en not_active Ceased
- 1997-01-24 EP EP97903981A patent/EP0877614B1/de not_active Expired - Lifetime
- 1997-01-24 WO PCT/US1997/001231 patent/WO1997026881A1/en active IP Right Grant
- 1997-01-24 CN CNB971926689A patent/CN1220490C/zh not_active Expired - Fee Related
- 1997-01-24 DE DE69713570T patent/DE69713570T2/de not_active Expired - Fee Related
- 1997-01-24 AT AT97903981T patent/ATE219676T1/de active
- 1997-01-27 ID IDP970229A patent/ID18975A/id unknown
- 1997-01-27 ZA ZA9700676A patent/ZA97676B/xx unknown
- 1997-01-27 AR ARP970100324A patent/AR005569A1/es not_active Application Discontinuation
- 1997-03-14 TW TW086103221A patent/TW475897B/zh not_active IP Right Cessation
- 1997-12-10 US US08/988,056 patent/US6054437A/en not_active Expired - Fee Related
- 1997-12-10 US US08/987,816 patent/US5859013A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69713570D1 (de) | 2002-08-01 |
| EP0877614B1 (de) | 2002-06-26 |
| US6054437A (en) | 2000-04-25 |
| CA2242657A1 (en) | 1997-07-31 |
| DE69713570T2 (de) | 2003-01-23 |
| CN1220490C (zh) | 2005-09-28 |
| AU1840297A (en) | 1997-08-20 |
| CN1212623A (zh) | 1999-03-31 |
| JP4117404B2 (ja) | 2008-07-16 |
| EP0877614A1 (de) | 1998-11-18 |
| US5859013A (en) | 1999-01-12 |
| AR005569A1 (es) | 1999-06-23 |
| US5733911A (en) | 1998-03-31 |
| KR100468271B1 (ko) | 2005-07-05 |
| TW475897B (en) | 2002-02-11 |
| ZA97676B (en) | 1997-08-25 |
| ID18975A (id) | 1998-05-28 |
| WO1997026881A1 (en) | 1997-07-31 |
| KR19990082064A (ko) | 1999-11-15 |
| AU731125B2 (en) | 2001-03-22 |
| JP2000505792A (ja) | 2000-05-16 |
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