ID18975A - Metode untuk induksi kematian sel-sel neoplastik dengan menggunakan turunan piperazin - Google Patents

Metode untuk induksi kematian sel-sel neoplastik dengan menggunakan turunan piperazin

Info

Publication number
ID18975A
ID18975A IDP970229A ID970229A ID18975A ID 18975 A ID18975 A ID 18975A ID P970229 A IDP970229 A ID P970229A ID 970229 A ID970229 A ID 970229A ID 18975 A ID18975 A ID 18975A
Authority
ID
Indonesia
Prior art keywords
derivity
piperazine
death
induction
methods
Prior art date
Application number
IDP970229A
Other languages
English (en)
Inventor
Gabriel F Eilon
John W Jacobs
Original Assignee
Hitachi Chemical Co Ltd Cs
Hitachi Chemical Res Ct Inc
Nippon Chemiphar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Chemical Co Ltd Cs, Hitachi Chemical Res Ct Inc, Nippon Chemiphar filed Critical Hitachi Chemical Co Ltd Cs
Publication of ID18975A publication Critical patent/ID18975A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IDP970229A 1996-01-26 1997-01-27 Metode untuk induksi kematian sel-sel neoplastik dengan menggunakan turunan piperazin ID18975A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/592,540 US5733911A (en) 1996-01-26 1996-01-26 Method for inducing death of neoplastic cells using piperazne derivatives

Publications (1)

Publication Number Publication Date
ID18975A true ID18975A (id) 1998-05-28

Family

ID=24371096

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP970229A ID18975A (id) 1996-01-26 1997-01-27 Metode untuk induksi kematian sel-sel neoplastik dengan menggunakan turunan piperazin

Country Status (14)

Country Link
US (3) US5733911A (id)
EP (1) EP0877614B1 (id)
JP (1) JP4117404B2 (id)
KR (1) KR100468271B1 (id)
CN (1) CN1220490C (id)
AR (1) AR005569A1 (id)
AT (1) ATE219676T1 (id)
AU (1) AU731125B2 (id)
CA (1) CA2242657A1 (id)
DE (1) DE69713570T2 (id)
ID (1) ID18975A (id)
TW (1) TW475897B (id)
WO (1) WO1997026881A1 (id)
ZA (1) ZA97676B (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843992A (en) * 1995-03-31 1998-12-01 Nippon Chemiphar Co., Ltd. Epoxysuccinic acid derivatives
US5733911A (en) * 1996-01-26 1998-03-31 Hitachi Chemical Co., Ltd. Method for inducing death of neoplastic cells using piperazne derivatives
US6387908B1 (en) * 1997-09-04 2002-05-14 Nippon Chemiphar Co., Ltd. Epoxysuccinamide derivatives
EP1094063A1 (en) 1999-10-18 2001-04-25 Applied Research Systems ARS Holding N.V. 9-(Piperazinylalkyl)carbazoles as Bax-modulators
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) * 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
EP1332139B1 (en) * 2000-10-23 2007-04-04 Arizona Biomedical Research Commission Anticancer agents based on regulation of protein prenylation
WO2003044535A1 (en) * 2001-11-22 2003-05-30 Mehmet Ozturk Method, antigen and antibody for distinguishing viable and apoptotic cells
WO2015013581A1 (en) 2013-07-26 2015-01-29 Update Pharma Inc. Combinatorial methods to improve the therapeutic benefit of bisantrene
PL407922A1 (pl) * 2014-04-16 2015-10-26 Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością Nowe bisfosfoniany i ich zastosowanie

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55115878A (en) * 1979-02-27 1980-09-06 Taisho Pharmaceut Co Ltd Epoxysuccinic acid derivative
JPS55153778A (en) * 1979-05-17 1980-11-29 Taisho Pharmaceut Co Ltd Epoxysuccinylamino acid derivative
US4474800A (en) * 1980-05-13 1984-10-02 Taisho Pharmaceutical Co., Ltd. Epoxysuccinyl amino acid derivatives
JPS57169478A (en) * 1981-04-10 1982-10-19 Nippon Chemiphar Co Ltd Piperazine derivative
JPS6276A (ja) * 1985-03-26 1987-01-06 Toyo Jozo Co Ltd 酵素阻害性新規物質
JPH0832698B2 (ja) * 1987-05-08 1996-03-29 日本ケミファ株式会社 ピペラジン誘導体
EP0460239A4 (en) * 1989-12-27 1992-05-06 Japan Tobacco Inc. 1,3,2-dioxathiolane oxide derivative
WO1993006143A1 (fr) * 1991-09-19 1993-04-01 Cray Valley Sa Resines de petrole thermiquement stables, leur procede de preparation et leur application a la formulation d'adhesifs thermofusibles
JPH0641067A (ja) * 1992-04-20 1994-02-15 Kitasato Inst:The 新規カルパイン阻害物質ｋｐ−１２４１及びその製造法
DE69321087T2 (de) * 1992-12-25 1999-05-20 Mitsubishi Chemical Corp., Tokio/Tokyo Alpha-aminoketon Derivate
US5733911A (en) * 1996-01-26 1998-03-31 Hitachi Chemical Co., Ltd. Method for inducing death of neoplastic cells using piperazne derivatives

Also Published As

Publication number Publication date
DE69713570T2 (de) 2003-01-23
ZA97676B (en) 1997-08-25
ATE219676T1 (de) 2002-07-15
CN1212623A (zh) 1999-03-31
US6054437A (en) 2000-04-25
US5859013A (en) 1999-01-12
EP0877614B1 (en) 2002-06-26
AU1840297A (en) 1997-08-20
CA2242657A1 (en) 1997-07-31
KR100468271B1 (ko) 2005-07-05
CN1220490C (zh) 2005-09-28
TW475897B (en) 2002-02-11
KR19990082064A (ko) 1999-11-15
JP2000505792A (ja) 2000-05-16
JP4117404B2 (ja) 2008-07-16
AU731125B2 (en) 2001-03-22
EP0877614A1 (en) 1998-11-18
DE69713570D1 (de) 2002-08-01
AR005569A1 (es) 1999-06-23
US5733911A (en) 1998-03-31
WO1997026881A1 (en) 1997-07-31

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