ATE215964T1 - Phrothrombin und thrombin bindende peptide. - Google Patents

Phrothrombin und thrombin bindende peptide.

Info

Publication number
ATE215964T1
ATE215964T1 AT97109744T AT97109744T ATE215964T1 AT E215964 T1 ATE215964 T1 AT E215964T1 AT 97109744 T AT97109744 T AT 97109744T AT 97109744 T AT97109744 T AT 97109744T AT E215964 T1 ATE215964 T1 AT E215964T1
Authority
AT
Austria
Prior art keywords
leu
gly
tyr
trp
pro
Prior art date
Application number
AT97109744T
Other languages
German (de)
English (en)
Inventor
George A Baumbach
Joseph A Buettner
Christopher A Dadd
David J Hammond
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE215964T1 publication Critical patent/ATE215964T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6429Thrombin (3.4.21.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21005Thrombin (3.4.21.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
AT97109744T 1996-06-28 1997-06-16 Phrothrombin und thrombin bindende peptide. ATE215964T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/672,805 US5831003A (en) 1996-06-28 1996-06-28 Peptides which bind to prothrombin and thrombin

Publications (1)

Publication Number Publication Date
ATE215964T1 true ATE215964T1 (de) 2002-04-15

Family

ID=24700072

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97109744T ATE215964T1 (de) 1996-06-28 1997-06-16 Phrothrombin und thrombin bindende peptide.

Country Status (10)

Country Link
US (1) US5831003A (cg-RX-API-DMAC7.html)
EP (1) EP0816377B1 (cg-RX-API-DMAC7.html)
JP (1) JP3978258B2 (cg-RX-API-DMAC7.html)
AT (1) ATE215964T1 (cg-RX-API-DMAC7.html)
AU (1) AU712575B2 (cg-RX-API-DMAC7.html)
CA (1) CA2206663A1 (cg-RX-API-DMAC7.html)
DE (1) DE69711765T2 (cg-RX-API-DMAC7.html)
DK (1) DK0816377T3 (cg-RX-API-DMAC7.html)
ES (1) ES2175218T3 (cg-RX-API-DMAC7.html)
PT (1) PT816377E (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6462180B1 (en) * 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
CA2432641A1 (en) 2000-12-14 2002-06-20 Bayer Corporation Method of preparing alpha-1 proteinase inhibitor
GB0211849D0 (en) * 2002-05-23 2002-07-03 Mok Kenneth H Improvments to retro-inverso isomers
FR2884418B1 (fr) * 2005-04-15 2008-11-21 Soc Extraction Principes Actif Utilisation d'un peptide comme principe actif amincissant
EP2502628B1 (en) 2006-06-23 2016-12-14 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in cancer
US9855291B2 (en) 2008-11-03 2018-01-02 Adc Therapeutics Sa Anti-kidney associated antigen 1 (KAAG1) antibodies
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
SMT201900505T1 (it) 2011-03-31 2019-11-13 Adc Therapeutics Sa Anticorpi contro l'antigene 1 associato ai reni e loro frammenti leganti l'antigene
CA2857400A1 (en) 2012-01-09 2013-07-18 Alethia Biotherapeutics Inc. Anti-kaag1 antibodies or antigen binding fragment thereof for treatment of triple negative breast cancer
EP3262409B1 (en) 2015-02-25 2020-03-25 Omrix Biopharmaceuticals Ltd. Method for purifying and quantifying thrombin and its degradation polypeptides
ES2791982T3 (es) * 2015-02-25 2020-11-06 Omrix Biopharmaceuticals Ltd Método para purificar y cuantificar la trombina y sus polipéptidos de degradación

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
US5367060A (en) * 1991-05-24 1994-11-22 Genentech, Inc. Structure, production and use of heregulin

Also Published As

Publication number Publication date
EP0816377A3 (en) 1998-07-15
EP0816377B1 (en) 2002-04-10
JPH1075778A (ja) 1998-03-24
US5831003A (en) 1998-11-03
DK0816377T3 (da) 2002-07-22
ES2175218T3 (es) 2002-11-16
EP0816377A2 (en) 1998-01-07
CA2206663A1 (en) 1997-12-28
AU712575B2 (en) 1999-11-11
DE69711765T2 (de) 2002-10-02
AU2622097A (en) 1998-01-15
PT816377E (pt) 2002-08-30
JP3978258B2 (ja) 2007-09-19
DE69711765D1 (de) 2002-05-16

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Legal Events

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UEP Publication of translation of european patent specification