ATE214711T1 - Liganden des urokinaserezeptors - Google Patents

Liganden des urokinaserezeptors

Info

Publication number
ATE214711T1
ATE214711T1 AT96919248T AT96919248T ATE214711T1 AT E214711 T1 ATE214711 T1 AT E214711T1 AT 96919248 T AT96919248 T AT 96919248T AT 96919248 T AT96919248 T AT 96919248T AT E214711 T1 ATE214711 T1 AT E214711T1
Authority
AT
Austria
Prior art keywords
lower alkyl
halo
aryl
alkyl
cycloalkyl
Prior art date
Application number
AT96919248T
Other languages
English (en)
Inventor
Steve Rosenberg
Kerry L Spear
Eric J Martin
Original Assignee
Chiron Corp
Steve Rosenberg
Kerry L Spear
Eric J Martin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp, Steve Rosenberg, Kerry L Spear, Eric J Martin filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE214711T1 publication Critical patent/ATE214711T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT96919248T 1995-06-07 1996-06-06 Liganden des urokinaserezeptors ATE214711T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/485,021 US5747458A (en) 1995-06-07 1995-06-07 Urokinase receptor ligands
PCT/US1996/009648 WO1996040747A1 (en) 1995-06-07 1996-06-06 Urokinase receptor ligands

Publications (1)

Publication Number Publication Date
ATE214711T1 true ATE214711T1 (de) 2002-04-15

Family

ID=23926620

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96919248T ATE214711T1 (de) 1995-06-07 1996-06-06 Liganden des urokinaserezeptors

Country Status (14)

Country Link
US (2) US5747458A (de)
EP (1) EP0777680B1 (de)
JP (1) JPH10503784A (de)
AT (1) ATE214711T1 (de)
AU (1) AU6164096A (de)
BR (1) BR9606429A (de)
CA (1) CA2196334A1 (de)
DE (1) DE69619940T2 (de)
FI (1) FI970446A7 (de)
HU (1) HUP9702220A3 (de)
IL (1) IL120101A0 (de)
MX (1) MX9700888A (de)
NO (1) NO970513L (de)
WO (1) WO1996040747A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519120A (en) * 1989-04-07 1996-05-21 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor antibodies
ID24525A (id) * 1997-07-31 2000-07-20 Hoffmann La Roche Turunan-turunan hidroksikumaranon tersubstitusi-0 sebagai zat anti tumor dan zat antimetastatik
WO1999055688A1 (en) * 1998-04-27 1999-11-04 Warner-Lambert Company Substituted diarylalkyl amides as calcium channel antagonists
US6228985B1 (en) 1998-05-21 2001-05-08 Schering Corporation Derivatives of aminobenzoic and aminobiphenylcarboxylic acids useful as anti-cancer agents
ES2169690B1 (es) * 2000-10-06 2004-03-16 Diverdrugs Sl Trimeros de n-alquilglicina capaces de proteger a neuronas contra agresiones excitotoxicas, y composiciones que los contienen.
ES2169691B1 (es) * 2000-10-11 2004-03-16 Diverdrugs Sl Trimeros de n-alquilglicina capaces de bloquear la respuesta a sustancias quimicas, estimulos termicos o mediadores de la inflamacion de receptores neuronales, y composiciones que los contienen.
CA2522203A1 (en) * 2003-04-15 2004-10-28 Gema Tarrason Identification of n-alkylglycine trimers for induction of apoptosis
CN103270022B (zh) 2010-08-31 2015-08-19 巴勃罗·比咯斯拉达 神经营养蛋白受体激动剂及其作为药物的应用
EP2647622B1 (de) * 2010-12-03 2017-04-19 Fujitsu Limited Kinesinspindelproteinhemmer sowie ihre verwendung
IT202100023357A1 (it) 2021-09-09 2023-03-09 Cheirontech S R L Peptidi con attività anti-angiogenica

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247080A (en) * 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
WO1986000991A1 (en) * 1984-07-24 1986-02-13 Commonwealth Serum Laboratories Commission Method for determining mimotopes
NZ215865A (en) * 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
IE66205B1 (en) * 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
PL308204A1 (en) * 1992-09-24 1995-07-24 Chiron Corp Synthesis of n-substituted oligomers
US5536853A (en) * 1994-04-11 1996-07-16 Chiron Corporation Opiate receptor ligands
ZA953361B (en) * 1994-04-26 1996-01-12 Selectide Corp Factor Xa inhibitors

Also Published As

Publication number Publication date
DE69619940T2 (de) 2002-12-19
WO1996040747A1 (en) 1996-12-19
BR9606429A (pt) 1997-09-02
HUP9702220A2 (hu) 1998-05-28
EP0777680B1 (de) 2002-03-20
FI970446L (fi) 1997-03-26
JPH10503784A (ja) 1998-04-07
NO970513D0 (no) 1997-02-05
CA2196334A1 (en) 1996-12-19
IL120101A0 (en) 1997-04-15
EP0777680A1 (de) 1997-06-11
FI970446A0 (fi) 1997-02-03
MX9700888A (es) 1997-04-30
AU6164096A (en) 1996-12-30
NO970513L (no) 1997-02-05
HUP9702220A3 (en) 1998-06-29
DE69619940D1 (de) 2002-04-25
US5747458A (en) 1998-05-05
US6121240A (en) 2000-09-19
FI970446A7 (fi) 1997-03-26

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties