ATE208902T1 - Einwegmodul und verfahren für eine testanordnung für biologische proben - Google Patents

Einwegmodul und verfahren für eine testanordnung für biologische proben

Info

Publication number
ATE208902T1
ATE208902T1 AT95931041T AT95931041T ATE208902T1 AT E208902 T1 ATE208902 T1 AT E208902T1 AT 95931041 T AT95931041 T AT 95931041T AT 95931041 T AT95931041 T AT 95931041T AT E208902 T1 ATE208902 T1 AT E208902T1
Authority
AT
Austria
Prior art keywords
cartridge
sample
biological samples
prior
test arrangement
Prior art date
Application number
AT95931041T
Other languages
English (en)
Inventor
Robert J Shartle
Original Assignee
Biometric Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biometric Imaging Inc filed Critical Biometric Imaging Inc
Application granted granted Critical
Publication of ATE208902T1 publication Critical patent/ATE208902T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/07—Centrifugal type cuvettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B01F25/422—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path between stacked plates, e.g. grooved or perforated plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7172—Feed mechanisms characterised by the means for feeding the components to the mixer using capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7173—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25625—Dilution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT95931041T 1994-09-02 1995-08-31 Einwegmodul und verfahren für eine testanordnung für biologische proben ATE208902T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/300,360 US5627041A (en) 1994-09-02 1994-09-02 Disposable cartridge for an assay of a biological sample
PCT/US1995/011073 WO1996007919A1 (en) 1994-09-02 1995-08-31 A disposable cartridge and method for an assay of a biological sample

Publications (1)

Publication Number Publication Date
ATE208902T1 true ATE208902T1 (de) 2001-11-15

Family

ID=23158766

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95931041T ATE208902T1 (de) 1994-09-02 1995-08-31 Einwegmodul und verfahren für eine testanordnung für biologische proben

Country Status (8)

Country Link
US (2) US5627041A (de)
EP (1) EP0778950B1 (de)
JP (1) JPH10505672A (de)
AT (1) ATE208902T1 (de)
AU (1) AU700750B2 (de)
CA (1) CA2198854A1 (de)
DE (1) DE69523931T2 (de)
WO (1) WO1996007919A1 (de)

Families Citing this family (311)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631734A (en) * 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5840254A (en) * 1995-06-02 1998-11-24 Cdc Technologies, Inc. Apparatus for mixing fluids for analysis
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US6114122A (en) * 1996-03-26 2000-09-05 Affymetrix, Inc. Fluidics station with a mounting system and method of using
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
AU5895898A (en) * 1996-12-20 1998-07-17 Gamera Bioscience Corporation An affinity binding-based system for detecting particulates in a fluid
US6057165A (en) * 1997-02-07 2000-05-02 Becton, Dickinson And Company Quality control procedure for membrane flow-through diagnostic assay devices
US6495195B2 (en) 1997-02-14 2002-12-17 Arcturus Engineering, Inc. Broadband absorbing film for laser capture microdissection
US6126904A (en) * 1997-03-07 2000-10-03 Argonaut Technologies, Inc. Apparatus and methods for the preparation of chemical compounds
AU7591998A (en) * 1997-05-23 1998-12-11 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
CA2301095A1 (en) 1997-08-15 1999-02-25 Alexion Pharmaceuticals, Inc. Apparatus for performing assays at reaction sites
US7075640B2 (en) * 1997-10-01 2006-07-11 Arcturus Bioscience, Inc. Consumable for laser capture microdissection
AU759239B2 (en) * 1997-11-28 2003-04-10 Provalis Diagnostics Limited Device and apparatus for conducting an assay
US7473401B1 (en) * 1997-12-04 2009-01-06 Mds Analytical Technologies (Us) Inc. Fluidic extraction of microdissected samples
US6009632A (en) * 1997-12-12 2000-01-04 Mercury Diagnostics, Inc. Alignment system for optical analyte testing meter components
US6117396A (en) * 1998-02-18 2000-09-12 Orchid Biocomputer, Inc. Device for delivering defined volumes
US6004821A (en) * 1998-03-07 1999-12-21 Levine; Robert A. Method and apparatus for performing chemical, qualitative, quantitative, and semi-quantitative analyses of a urine sample
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
GB9808836D0 (en) * 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
GB9809943D0 (en) * 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
US20040202579A1 (en) * 1998-05-08 2004-10-14 Anders Larsson Microfluidic device
CA2320296A1 (en) * 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6521182B1 (en) * 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
US6084660A (en) * 1998-07-20 2000-07-04 Lifescan, Inc. Initiation of an analytical measurement in blood
US6830934B1 (en) * 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
US6261519B1 (en) 1998-07-20 2001-07-17 Lifescan, Inc. Medical diagnostic device with enough-sample indicator
US6171870B1 (en) * 1998-08-06 2001-01-09 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6162400A (en) * 1998-08-12 2000-12-19 Agilent Technologies, Inc. Apparatus for controlling reactions
CA2349548C (en) * 1998-11-05 2012-09-25 Chemometec A/S A method for the assessment of particles and a system and a device for use in the method
US6200766B1 (en) 1998-12-03 2001-03-13 Becton Dickinson And Company Methods and reagents for quantitation of HLA-DR expression on peripheral blood cells
US6423505B1 (en) 1998-12-03 2002-07-23 Becton Dickinson And Company Methods and reagents for quantitation of HLA-DR and CD11b expression on peripheral blood cells
US6391264B2 (en) 1999-02-11 2002-05-21 Careside, Inc. Cartridge-based analytical instrument with rotor balance and cartridge lock/eject system
US6348176B1 (en) 1999-02-11 2002-02-19 Careside, Inc. Cartridge-based analytical instrument using centrifugal force/pressure for metering/transport of fluids
US6531095B2 (en) 1999-02-11 2003-03-11 Careside, Inc. Cartridge-based analytical instrument with optical detector
US6937330B2 (en) 1999-04-23 2005-08-30 Ppd Biomarker Discovery Sciences, Llc Disposable optical cuvette cartridge with low fluorescence material
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US6687395B1 (en) * 1999-07-21 2004-02-03 Surromed, Inc. System for microvolume laser scanning cytometry
JP3823053B2 (ja) 1999-08-06 2006-09-20 サーモ エレクトロン コーポレイション−ポイント オブ ケア エンド ラピッド ダイアグノスティックス 完全サンプル処理能力を備える、医療現場用検出自動化装置
EP2275807B1 (de) * 1999-11-15 2014-04-23 Panasonic Healthcare Co., Ltd. Biosensor zur Quantifizierung eines Substrats
US6488827B1 (en) 2000-03-31 2002-12-03 Lifescan, Inc. Capillary flow control in a medical diagnostic device
US6908593B1 (en) 2000-03-31 2005-06-21 Lifescan, Inc. Capillary flow control in a fluidic diagnostic device
EP1279020B1 (de) * 2000-04-26 2016-03-16 Life Technologies Corporation Vorrichtung und verfahren zur extraktion und flüssiger behandlung von proben nach einer laseranheftungs-mikrodissektion (lcm)
US20020151078A1 (en) * 2000-05-15 2002-10-17 Kellogg Gregory J. Microfluidics devices and methods for high throughput screening
AU2001263162A1 (en) * 2000-05-15 2001-11-26 Tecan Trading Ag Microfluidics devices and methods for high throughput screening
US6557427B2 (en) * 2000-05-24 2003-05-06 Micronics, Inc. Capillaries for fluid movement within microfluidic channels
US6511277B1 (en) 2000-07-10 2003-01-28 Affymetrix, Inc. Cartridge loader and methods
US6422249B1 (en) 2000-08-10 2002-07-23 Affymetrix Inc. Cartridge washing system and methods
GB0021887D0 (en) * 2000-09-06 2000-10-18 Provalis Diagnostics Ltd Assay device
US7026131B2 (en) * 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
US7087203B2 (en) * 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6787761B2 (en) * 2000-11-27 2004-09-07 Surromed, Inc. Median filter for liquid chromatography-mass spectrometry data
US20020095260A1 (en) * 2000-11-28 2002-07-18 Surromed, Inc. Methods for efficiently mining broad data sets for biological markers
CN100346158C (zh) * 2000-11-30 2007-10-31 松下电器产业株式会社 基质的定量方法
US20040099310A1 (en) * 2001-01-05 2004-05-27 Per Andersson Microfluidic device
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
CA2441206A1 (en) 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
US6852287B2 (en) * 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7192557B2 (en) * 2001-03-28 2007-03-20 Handylab, Inc. Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US6575188B2 (en) 2001-07-26 2003-06-10 Handylab, Inc. Methods and systems for fluid control in microfluidic devices
US7270786B2 (en) 2001-03-28 2007-09-18 Handylab, Inc. Methods and systems for processing microfluidic samples of particle containing fluids
US6653122B2 (en) 2001-04-24 2003-11-25 Dade Microscan Inc. Indentification test device in a random access microbiological analyzer
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
JP4209767B2 (ja) 2001-06-12 2009-01-14 ペリカン テクノロジーズ インコーポレイテッド 皮膚の性状の一時的変化に対する適応手段を備えた自動最適化形切開器具
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US6632654B1 (en) 2001-08-08 2003-10-14 Dade Microscan Inc. Canister for inventorying susceptability test devices in an automated microbiological analyzer
US6776966B2 (en) 2001-08-08 2004-08-17 Dade Behring Inc. Canister for inventorying identification test devices in an automated microbiological analyzer
US6573088B2 (en) 2001-08-08 2003-06-03 Dade Microscan Inc. Automated random access microbiological analyzer
US6855540B2 (en) * 2001-08-08 2005-02-15 Dade Behring Inc. Reagent container and canister for use in an automated microbiological analyzer
US6873915B2 (en) * 2001-08-24 2005-03-29 Surromed, Inc. Peak selection in multidimensional data
US20030078739A1 (en) * 2001-10-05 2003-04-24 Surromed, Inc. Feature list extraction from data sets such as spectra
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
SE521252C2 (sv) 2001-11-21 2003-10-14 Boule Medical Ab Engångsapparat för användning vid blodprov och instrument för användning med apparaten
US6739576B2 (en) 2001-12-20 2004-05-25 Nanostream, Inc. Microfluidic flow control device with floating element
WO2003065355A2 (en) * 2002-01-31 2003-08-07 Burstein Technologies, Inc. Bio-safety features for optical analysis disc and disc system including same
US7459127B2 (en) * 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
EP1345026B1 (de) * 2002-03-15 2010-05-05 Affymetrix, Inc. System und Verfahren zur Abtastung von biologischen Materialien
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US6989100B2 (en) * 2002-05-09 2006-01-24 Ppd Biomarker Discovery Sciences, Llc Methods for time-alignment of liquid chromatography-mass spectrometry data
FR2841158B1 (fr) * 2002-06-24 2007-02-23 Bio Merieux Dispositif fluidique permettant de maniere thermo-pneumatique l'isolement et eventuellement l'agitation du contenu d'une cavite operatoire
US20040120861A1 (en) * 2002-10-11 2004-06-24 Affymetrix, Inc. System and method for high-throughput processing of biological probe arrays
JP4368804B2 (ja) * 2002-12-02 2009-11-18 ユィロス・パテント・アクチボラグ 微小流体素子の並列処理
US7125711B2 (en) * 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2004060446A2 (en) * 2002-12-30 2004-07-22 Pelikan Technologies, Inc. Method and apparatus using optical techniques to measure analyte levels
US6983177B2 (en) 2003-01-06 2006-01-03 Optiscan Biomedical Corporation Layered spectroscopic sample element with microporous membrane
US7060225B2 (en) * 2003-03-20 2006-06-13 Northeastern Ohio Universities College Of Medicine Self-contained assay device for rapid detection of biohazardous agents
JP3888632B2 (ja) * 2003-03-26 2007-03-07 靖浩 堀池 マイクロミキサ、試料分析キット及びその製造方法
AU2004230531A1 (en) * 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Sample element qualification
US20050037384A1 (en) * 2003-04-15 2005-02-17 Braig James R. Analyte detection system
US20040219691A1 (en) * 2003-04-29 2004-11-04 Shartle Robert J. Test strip with clear base support layer for visual perception of a liquid sample during application
US7435381B2 (en) * 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
EP2238892A3 (de) 2003-05-30 2011-02-09 Pelikan Technologies Inc. Vorrichtung zur Entnahme von Körperflüssigkeit
ES2490740T3 (es) 2003-06-06 2014-09-04 Sanofi-Aventis Deutschland Gmbh Aparato para toma de muestras de fluido sanguíneo y detección de analitos
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
WO2004113871A2 (en) * 2003-06-19 2004-12-29 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
WO2005011830A2 (en) * 2003-07-25 2005-02-10 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
EP1654066B1 (de) 2003-07-31 2014-11-12 Handylab, Inc. Verarbeitung von teilchenhaltigen proben
US7317415B2 (en) 2003-08-08 2008-01-08 Affymetrix, Inc. System, method, and product for scanning of biological materials employing dual analog integrators
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
JP3959436B2 (ja) * 2003-08-29 2007-08-15 独立行政法人物質・材料研究機構 流れ変動構造及びマイクロミキサ
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US7147362B2 (en) * 2003-10-15 2006-12-12 Agilent Technologies, Inc. Method of mixing by intermittent centrifugal force
US7837947B2 (en) * 2003-12-12 2010-11-23 3M Innovative Properties Company Sample mixing on a microfluidic device
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US20050178218A1 (en) * 2004-01-28 2005-08-18 Jean Montagu Micro-volume blood sampling device
US20050170513A1 (en) * 2004-02-04 2005-08-04 Hach Company Analytical rotor system for titration testing
US20050169804A1 (en) * 2004-02-04 2005-08-04 Hach Company User-configurable analytical rotor system
US20050169805A1 (en) * 2004-02-04 2005-08-04 Hach Company Analytical rotor system with a sample chamber
US20050170515A1 (en) * 2004-02-04 2005-08-04 Hach Company Analytical rotor system with an analytical signal path
US20050170514A1 (en) * 2004-02-04 2005-08-04 Hach Company Analytical rotor system for method of standard additions testing
US7588724B2 (en) * 2004-03-05 2009-09-15 Bayer Healthcare Llc Mechanical device for mixing a fluid sample with a treatment solution
US7248360B2 (en) 2004-04-02 2007-07-24 Ppd Biomarker Discovery Sciences, Llc Polychronic laser scanning system and method of use
WO2005100539A2 (en) 2004-04-07 2005-10-27 Levine, Robert, A. Disposable chamber for analyzing biologic fluids
EP2345739B8 (de) 2004-05-03 2016-12-07 Handylab, Inc. Mikrofluidische Vorrichtung zur Verarbeitung polynukleotidhaltiger Proben
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
MXPA06012707A (es) 2004-05-04 2007-03-26 Metrika Inc Cartucho mecanico con caracteristicas de control de fluido en tira de prueba, para utilizar en un medidor de analitos fluidos.
WO2005111580A1 (en) * 2004-05-07 2005-11-24 Optiscan Biomedical Corporation Sample element with fringing-reduction capabilities
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US8343074B2 (en) * 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US20060000709A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Methods for modulation of flow in a flow pathway
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
WO2006061026A2 (en) * 2004-12-09 2006-06-15 Inverness Medical Switzerland Gmbh A micro fluidic device and methods for producing a micro fluidic device
WO2006070772A1 (en) * 2004-12-28 2006-07-06 Matsushita Electric Industrial Co., Ltd. Testing device and blood mixing and diluting method
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US20100089529A1 (en) * 2005-01-12 2010-04-15 Inverness Medical Switzerland Gmbh Microfluidic devices and production methods therefor
JP4422623B2 (ja) * 2005-01-17 2010-02-24 株式会社日立ハイテクノロジーズ 化学分析装置および化学分析カートリッジ
US8936755B2 (en) 2005-03-02 2015-01-20 Optiscan Biomedical Corporation Bodily fluid composition analyzer with disposable cassette
US8251907B2 (en) * 2005-02-14 2012-08-28 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US20060195058A1 (en) 2005-02-14 2006-08-31 Gable Jennifer H Methods and apparatus for extracting and analyzing a bodily fluid
US7957507B2 (en) 2005-02-28 2011-06-07 Cadman Patrick F Method and apparatus for modulating a radiation beam
WO2006106608A1 (ja) * 2005-04-04 2006-10-12 Matsushita Electric Industrial Co., Ltd. 液体均一化装置およびそれを用いた分析装置
US20060246576A1 (en) * 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
USD540953S1 (en) * 2005-05-04 2007-04-17 Metrika, Inc. Test meter cartridge
US8232535B2 (en) 2005-05-10 2012-07-31 Tomotherapy Incorporated System and method of treating a patient with radiation therapy
US20060275852A1 (en) * 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
WO2007006315A2 (en) * 2005-07-07 2007-01-18 Inverness Medical Switzerland Gmbh A method of performing a test, a support instrument and a microliquid system comprising such support instrument
US7574251B2 (en) 2005-07-22 2009-08-11 Tomotherapy Incorporated Method and system for adapting a radiation therapy treatment plan based on a biological model
CN101268474A (zh) * 2005-07-22 2008-09-17 断层放疗公司 用于估算实施剂量的方法和系统
US20070195922A1 (en) * 2005-07-22 2007-08-23 Mackie Thomas R System and method of monitoring the operation of a medical device
WO2007014106A2 (en) * 2005-07-22 2007-02-01 Tomotherapy Incorporated System and method of delivering radiation therapy to a moving region of interest
WO2007014091A2 (en) 2005-07-22 2007-02-01 Tomotherapy Incorporated System and method of generating contour structures using a dose volume histogram
US7567694B2 (en) * 2005-07-22 2009-07-28 Tomotherapy Incorporated Method of placing constraints on a deformation map and system for implementing same
US7839972B2 (en) 2005-07-22 2010-11-23 Tomotherapy Incorporated System and method of evaluating dose delivered by a radiation therapy system
US7639854B2 (en) 2005-07-22 2009-12-29 Tomotherapy Incorporated Method and system for processing data relating to a radiation therapy treatment plan
US8442287B2 (en) * 2005-07-22 2013-05-14 Tomotherapy Incorporated Method and system for evaluating quality assurance criteria in delivery of a treatment plan
US7773788B2 (en) 2005-07-22 2010-08-10 Tomotherapy Incorporated Method and system for evaluating quality assurance criteria in delivery of a treatment plan
JP5060476B2 (ja) 2005-07-22 2012-10-31 トモセラピー・インコーポレーテッド 放射線療法を受けている患者の呼吸位相を検出するシステムおよび方法
JP2009506800A (ja) 2005-07-22 2009-02-19 トモセラピー・インコーポレーテッド 線量デリバリを予測する方法およびシステム
EP3175886B1 (de) 2005-07-23 2018-06-27 TomoTherapy, Inc. Strahlungstherapiebildgebung und abgabe mittels koordinierter bewegung von gantry und liege
EP1752755B1 (de) 2005-08-10 2015-05-06 Roche Diagnostics GmbH Probenaufnahme- und-dosiervorrichtung mit integrierten Flüssigkeitskompartimenten
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
US7731901B2 (en) 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
US7651869B2 (en) * 2006-03-14 2010-01-26 Research International, Inc. Optical assay apparatus and methods
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US9040288B2 (en) 2006-03-24 2015-05-26 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using the same
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7771655B2 (en) * 2006-07-12 2010-08-10 Bayer Healthcare Llc Mechanical device for mixing a fluid sample with a treatment solution
US7749773B2 (en) * 2006-10-11 2010-07-06 Day Alan R Device for detection of molecules in biological fluids
FR2907226B1 (fr) * 2006-10-13 2008-12-12 Rhodia Recherches & Tech Dispositif d'analyse fluidique,dispositif de determination de caracteristiques d'un fluide comprenant ce dispositif d'analyse,procedes de mise en oeuvre et procede de criblage correspondants
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
EP2101917A1 (de) * 2007-01-10 2009-09-23 Scandinavian Micro Biodevices A/S Mikrofluidische vorrichtung und mikrofluidisches system und verfahren zur testdurchführung
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
ES2648798T3 (es) 2007-07-13 2018-01-08 Handylab, Inc. Materiales de captura de polinucleótidos y métodos de utilización de los mismos
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
JP4614992B2 (ja) * 2007-07-27 2011-01-19 パナソニック株式会社 分析用デバイスとこれを使用する分析装置および分析方法
US8381169B2 (en) * 2007-10-30 2013-02-19 International Business Machines Corporation Extending unified process and method content to include dynamic and collaborative content
WO2009060849A1 (ja) * 2007-11-05 2009-05-14 Nippon Kayaku Kabushiki Kaisha バイオセンサ
US8001855B2 (en) * 2008-01-14 2011-08-23 Medi Medical Engineering Corp. Fluid transferring apparatus
US8187538B2 (en) * 2008-01-17 2012-05-29 Ortho-Clinical Diagnostics, Inc. Diluent wells produced in card format for immunodiagnostic testing
CN102118998B (zh) * 2008-03-05 2016-02-10 贝克顿·迪金森公司 毛细管作用采集装置和容器组件
EP2254699A1 (de) * 2008-03-11 2010-12-01 Koninklijke Philips Electronics N.V. Filterungsvorrichtung zum filtern einer flüssigkeit
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US8063236B2 (en) * 2008-05-08 2011-11-22 University Of Florida Research Foundation, Inc. Method for transferring N-atoms from metal complexes to organic and inorganic substrates
EP2133149A1 (de) * 2008-06-13 2009-12-16 F.Hoffmann-La Roche Ag Lab-on-Disc-Vorrichtung
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US7947492B2 (en) * 2008-08-20 2011-05-24 Northeastern Ohio Universities College Of Medicine Device improving the detection of a ligand
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
CA2752715C (en) 2009-04-14 2018-05-01 Arie R. Van Doorn Hifu induced cavitation with reduced power threshold
WO2010118542A1 (en) 2009-04-15 2010-10-21 Biocartis Sa Protection of bioanalytical sample chambers
BRPI1012522B1 (pt) 2009-04-15 2019-11-26 Biocartis N V sistema ótico de multiplexação e método para detectar componentes de amostra em pelo menos duas câmaras de amostra diferentes
EP2244228A1 (de) 2009-04-21 2010-10-27 Koninklijke Philips Electronics N.V. Verfahren und Vorrichtung zum Abtasten eines Schiebers oder einer Kartusche mit Mikroobjekten
EP2427270B1 (de) 2009-05-06 2015-04-01 Biocartis NV Vorrichtung zum schneiden eines probenträgers
EP2253958B1 (de) * 2009-05-18 2013-04-17 F. Hoffmann-La Roche AG Auf Zentrifugalkraft basierendes mikrofluidisches System und Verfahren zur automatischen Probenanalyse
US9767342B2 (en) 2009-05-22 2017-09-19 Affymetrix, Inc. Methods and devices for reading microarrays
EP2456355B1 (de) 2009-07-20 2016-09-14 Optiscan Biomedical Corporation Einstellbarer steckverbinder und totraumreduzierung dafür
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
US20110085950A1 (en) * 2009-10-08 2011-04-14 Samsung Electronics Co., Ltd. Centrifugal force based microfluidic system and bio cartridge for the microfluidic system
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
WO2011053631A1 (en) 2009-10-28 2011-05-05 Alentic Microscience Inc. Microscopy imaging
US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
US9579651B2 (en) * 2009-12-18 2017-02-28 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
CA2796586C (en) * 2010-02-23 2017-10-24 Genturadx-Usa, Inc. Apparatus and methods for integrated sample preparation, reaction and detection
CN102859365B (zh) * 2010-04-15 2016-01-20 洛伊克德克斯有限公司 用于快速确定医学疾病的设备、系统和方法
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011156522A1 (en) 2010-06-09 2011-12-15 Optiscan Biomedical Corporation Measuring analytes in a fluid sample drawn from a patient
WO2012075256A2 (en) * 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Sample metering device and assay device with integrated sample dilution
WO2012075263A1 (en) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Assay devices with integrated sample dilution and dilution verification and methods of using same
US9034634B2 (en) * 2010-12-03 2015-05-19 Abbott Point Of Care Inc. Sample metering device and assay device with integrated sample dilution
ES2533839T3 (es) 2010-12-30 2015-04-15 Abbott Point Of Care, Inc. Cartucho de análisis de fluido biológico con porción de manipulación de muestra y porción de cámara de análisis
CN106190806B (zh) 2011-04-15 2018-11-06 贝克顿·迪金森公司 扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法
WO2012151473A2 (en) 2011-05-04 2012-11-08 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
EP2729784A4 (de) 2011-07-06 2015-05-13 Optiscan Biomedical Corp Messzelle für flüssigkeitsanalysesystem
CN105817276B (zh) 2011-08-24 2018-02-06 艾博特健康公司 生物流体样品分析盒
DK2761305T3 (da) 2011-09-30 2017-11-20 Becton Dickinson Co Forenet reagensstrimmel
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
USD679024S1 (en) * 2011-10-20 2013-03-26 Panasonic Corporation Chip for biochemical examination
USD676145S1 (en) * 2011-10-20 2013-02-12 Panasonic Corporation Chip for biochemical examination
DE102011117588A1 (de) * 2011-11-03 2013-05-08 Linde Aktiengesellschaft Einrichtung zur Herstellung eines Phasenkontaktes zwischen einer flüssigen und einer gasförmigen Phase, insbesondere Stoffaustauschkolonne
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
USD709620S1 (en) * 2012-01-13 2014-07-22 Hewlett-Packard Development Company, L. P. Fluidic dispense device
DK2810080T3 (da) 2012-02-03 2024-06-17 Becton Dickinson Co Eksterne filer til fordeling af molekylære diagnostiske tests og bestemmelse af kompatabilitet imellem tests
EP2634579B1 (de) * 2012-03-03 2014-12-17 Astrium GmbH Verfahren zur Durchführung von Immuno-Assays in Schwerelosigkeit
DE102012205171B3 (de) 2012-03-29 2013-09-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Integriertes Einweg-Chipkartuschensystem für mobile Multiparameteranalysen chemischer und/oder biologischer Substanzen
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
AU2012381985A1 (en) * 2012-06-05 2015-01-29 Dairy Quality Inc. Biological fluid analysis system and method
TWI484182B (zh) * 2012-11-07 2015-05-11 Taidoc Technology Corp 反應容器、分析裝置及分析方法
US9724689B2 (en) * 2012-11-20 2017-08-08 Detectachem Llc Colorimetric test system designed to control flow of simultaneously released chemicals to a target area
EP2929345A4 (de) * 2012-12-06 2015-11-18 Abbott Point Of Care Inc Abbildung biologischer flüssigkeiten mittels einer vorbestimmten verteilung
JP6363093B2 (ja) 2012-12-13 2018-07-25 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 流体ストップを備える流体システム
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
EP3508848B1 (de) 2012-12-17 2022-10-05 Accellix Ltd Systeme und verfahren zur bestimmung eines chemischen zustandes
US9518920B2 (en) 2013-06-26 2016-12-13 Alentic Microscience Inc. Sample processing improvements for microscopy
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
CN105027227B (zh) 2013-02-26 2017-09-08 安科锐公司 电磁致动的多叶准直器
USD733313S1 (en) * 2013-03-19 2015-06-30 Panasonic Healthcare Holdings Co., Ltd. Chip for biochemical examination
WO2015017413A1 (en) * 2013-07-29 2015-02-05 Mbio Diagnostics, Inc. Assay cartridge processing systems and methods and associated assay cartridges
US9536304B2 (en) 2013-08-30 2017-01-03 Dairy Quality Inc. Determining pathogens based on an image of somatic cells in a fluid sample
WO2015187849A2 (en) 2014-06-04 2015-12-10 Lucigen Corporation Sample collection and analysis devices
US10539582B2 (en) 2014-06-30 2020-01-21 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and method for removing liquid from liquid that contains magnetic particles
US10309976B2 (en) 2014-06-30 2019-06-04 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
US10520521B2 (en) 2014-06-30 2019-12-31 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
WO2016002731A1 (ja) 2014-06-30 2016-01-07 パナソニックヘルスケアホールディングス株式会社 試料分析用基板および試料分析装置
WO2016093332A1 (ja) 2014-12-12 2016-06-16 パナソニックヘルスケアホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
US10493448B2 (en) 2015-03-13 2019-12-03 Bio-Rad Laboratories, Inc. Assay cartridge
USD804682S1 (en) * 2015-08-10 2017-12-05 Opko Diagnostics, Llc Multi-layered sample cassette
EP3136106A1 (de) * 2015-08-28 2017-03-01 Siemens Healthcare Diagnostics Products GmbH Photometrische analyse einer probenflüssigkeit
JP6792568B2 (ja) * 2015-12-24 2020-11-25 Ｐｈｃホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
PL3416556T3 (pl) 2016-02-17 2020-12-28 Polymer Technology Systems, Inc. Systemy dla przyrządu do pobierania krwi o powiększonej pojemności przy użyciu technik kapilarnych
DE102016213000A1 (de) 2016-07-15 2018-01-18 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Handhabung von Flüssigkeiten unter Verwendung eines Fluidikmoduls mit bezüglich einer Rotationsebene geneigter Fluidikebene
CN109475869B (zh) * 2016-07-18 2021-07-30 西门子医疗保健诊断公司 液体分析试剂分配设备及其相关的分析套件和使用方法
CN110892247B (zh) 2017-08-17 2023-08-25 雅培医护站股份有限公司 用于执行光学和电化学测定的设备、系统和方法
CN110869745B (zh) 2017-08-17 2023-08-11 雅培医护站股份有限公司 用于执行光学测定的设备、系统和方法
WO2019035082A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. TECHNIQUES FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS WITH UNIVERSAL CIRCUITS
JP7383611B2 (ja) * 2018-06-29 2023-11-20 Ｐｈｃホールディングス株式会社 試料採取デバイスおよび試料調製装置
JP7525483B2 (ja) 2018-11-20 2024-07-30 ザテック、インコーポレイテッド 誘電分光センシング装置及びその使用方法
JP7496368B2 (ja) 2019-03-12 2024-06-06 ノヴィラクス エルエルシー 診療地点濃度分析器
EP3977122A4 (de) * 2019-05-28 2023-06-21 Brian Kamradt Filtertoxin und antigendetektor
WO2020243741A1 (en) 2019-05-28 2020-12-03 Levine Robert A Apparatus and method for transferring and analyzing suspended particles in a liquid sample
WO2022219373A1 (en) * 2021-04-13 2022-10-20 Rynan Technologies Pte. Ltd. Spectrophotometric system and method for wireless water quality management of aquaculture basin
USD990700S1 (en) * 2022-09-15 2023-06-27 ANUME s.r.o. Biometric sensor

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799742A (en) * 1971-12-20 1974-03-26 C Coleman Miniaturized integrated analytical test container
US4125828A (en) * 1972-08-04 1978-11-14 Med-El Inc. Method and apparatus for automated classification and analysis of cells
US3829223A (en) * 1973-07-20 1974-08-13 Atomic Energy Commission Mixing rotor for fast analyzer of rotary cuvette type with means for enhancing the mixing of sample and reagent liquids
US3864089A (en) * 1973-12-10 1975-02-04 Atomic Energy Commission Multiple-sample rotor assembly for blood fraction preparation
US4225558A (en) * 1978-09-19 1980-09-30 Honeywell Inc. Fluid sample test apparatus and fluid sample cell for use therein
CA1152353A (en) * 1980-05-05 1983-08-23 Georges Revillet Multicuvette rotor for analyser
US4426451A (en) * 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
FI72660C (fi) * 1984-01-11 1987-07-10 Fluilogic Systems Oy Centrifugeringsfoerfarande och centrifug foer tillaempning av detsamma.
US4883763A (en) * 1984-05-03 1989-11-28 Abbott Laboratories Sample processor card for centrifuge
US4580898A (en) * 1984-05-31 1986-04-08 Allied Corporation Analytical system
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US5164598A (en) * 1985-08-05 1992-11-17 Biotrack Capillary flow device
US5004923A (en) * 1985-08-05 1991-04-02 Biotrack, Inc. Capillary flow device
US5173262A (en) * 1987-07-17 1992-12-22 Martin Marietta Energy Systems, Inc. Rotor assembly and method for automatically processing liquids
US5077017A (en) * 1987-11-05 1991-12-31 Biotrack, Inc. Integrated serial dilution and mixing cartridge
US4946795A (en) * 1987-08-27 1990-08-07 Biotrack, Inc. Apparatus and method for dilution and mixing of liquid samples
US4868129A (en) * 1987-08-27 1989-09-19 Biotrack Inc. Apparatus and method for dilution and mixing of liquid samples
US4999304A (en) * 1987-12-28 1991-03-12 Miles Inc. Dynamic braking centrifuge
FR2634892B1 (fr) * 1988-07-28 1990-09-14 Guigan Jean Dispositif pour la realisation d'analyses biologiques par detection immuno-enzymatique d'anticorps ou d'antigenes dans un serum
US5320808A (en) * 1988-08-02 1994-06-14 Abbott Laboratories Reaction cartridge and carousel for biological sample analyzer
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5104813A (en) * 1989-04-13 1992-04-14 Biotrack, Inc. Dilution and mixing cartridge
US5122284A (en) * 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
EP0608006B1 (de) * 1990-06-04 1999-03-10 Abaxis, Inc. Rotoren für die Analytik und Verfahren zur Analyse biologischer Fluide
US5173193A (en) * 1991-04-01 1992-12-22 Schembri Carol T Centrifugal rotor having flow partition
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
US5256376A (en) * 1991-09-12 1993-10-26 Medical Laboratory Automation, Inc. Agglutination detection apparatus
WO1993019827A1 (en) * 1992-04-02 1993-10-14 Abaxis, Inc. Analytical rotor with dye mixing chamber
US5338427A (en) * 1993-02-26 1994-08-16 Biometric Imaging Inc. Single use separation cartridge for a capillary electrophoresis instrument
US5478750A (en) * 1993-03-31 1995-12-26 Abaxis, Inc. Methods for photometric analysis
EP0764266A4 (de) * 1994-06-06 1998-08-05 Abay Sa Modifizierte siphone zur verbesserung der dosiergenauigkeit
USD366938S (en) 1994-09-02 1996-02-06 Biometric Imaging, Inc. Cartridge for processing laboratory samples

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WO1996007919A1 (en) 1996-03-14
DE69523931T2 (de) 2002-08-29
AU700750B2 (en) 1999-01-14
EP0778950A4 (de) 1998-11-04
AU3462795A (en) 1996-03-27
DE69523931D1 (de) 2001-12-20
CA2198854A1 (en) 1996-03-14
EP0778950B1 (de) 2001-11-14
US5627041A (en) 1997-05-06
US5912134A (en) 1999-06-15
JPH10505672A (ja) 1998-06-02

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