ATE200286T1 - Chinolincarbonsäure-derivate - Google Patents
Chinolincarbonsäure-derivateInfo
- Publication number
- ATE200286T1 ATE200286T1 AT95918742T AT95918742T ATE200286T1 AT E200286 T1 ATE200286 T1 AT E200286T1 AT 95918742 T AT95918742 T AT 95918742T AT 95918742 T AT95918742 T AT 95918742T AT E200286 T1 ATE200286 T1 AT E200286T1
- Authority
- AT
- Austria
- Prior art keywords
- acid derivatives
- carbonic acid
- quinoline
- quinoline carbonic
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10317794 | 1994-05-18 | ||
PCT/JP1995/000954 WO1995031455A1 (fr) | 1994-05-18 | 1995-05-18 | Derive d'acide quinolinecarboxylique |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE200286T1 true ATE200286T1 (de) | 2001-04-15 |
Family
ID=14347238
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95918742T ATE200286T1 (de) | 1994-05-18 | 1995-05-18 | Chinolincarbonsäure-derivate |
AT99123695T ATE316970T1 (de) | 1994-05-18 | 1995-05-18 | 8-(2,2,2-trifluoroethyl)-8-azabicyclo(3.2.1)oct n-3-on verwendbar als zwischenprodukt für serotonin-4-rezeptor stimulierende chinolincarbonsäure- derivate |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99123695T ATE316970T1 (de) | 1994-05-18 | 1995-05-18 | 8-(2,2,2-trifluoroethyl)-8-azabicyclo(3.2.1)oct n-3-on verwendbar als zwischenprodukt für serotonin-4-rezeptor stimulierende chinolincarbonsäure- derivate |
Country Status (11)
Country | Link |
---|---|
US (1) | US5753673A (de) |
EP (2) | EP0710662B1 (de) |
JP (1) | JP3829879B2 (de) |
KR (1) | KR960703907A (de) |
AT (2) | ATE200286T1 (de) |
AU (1) | AU685632B2 (de) |
CA (1) | CA2167055A1 (de) |
DE (2) | DE69534768T2 (de) |
DK (1) | DK1018513T3 (de) |
ES (1) | ES2252907T3 (de) |
WO (1) | WO1995031455A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2184366A1 (en) * | 1994-02-28 | 1995-08-31 | Yutaka Ohuchi | Heterocyclic compound |
EP1021443A4 (de) * | 1995-11-13 | 2001-02-07 | Smithkline Beecham Corp | Hamoregulationische verbindungen |
US6451813B1 (en) | 2001-01-26 | 2002-09-17 | R. T. Alamo Ventures I, Llc | Treatment of gastroparesis in certain patient groups |
US20050222175A1 (en) * | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
US7612078B2 (en) * | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
CA2545092C (en) * | 2003-11-24 | 2010-08-17 | Pfizer Inc. | Quinolonecarboxylic acid compounds having 5-ht4 receptor agonistic activity |
TW200533348A (en) * | 2004-02-18 | 2005-10-16 | Theravance Inc | Indazole-carboxamide compounds as 5-ht4 receptor agonists |
US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
US7728006B2 (en) * | 2004-04-07 | 2010-06-01 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
US7488736B2 (en) * | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
US7407966B2 (en) | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
US7598265B2 (en) * | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
US7576211B2 (en) | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
DE602005014566D1 (de) * | 2004-11-05 | 2009-07-02 | Theravance Inc | Chinolinon-carboxamid-verbindungen |
US7399862B2 (en) * | 2004-11-05 | 2008-07-15 | Theravance, Inc. | 5-HT4 receptor agonist compounds |
BRPI0519708A2 (pt) * | 2004-12-22 | 2009-03-10 | Theravance Inc | compostos de indazol-carboxamida |
JP2008530225A (ja) * | 2005-02-17 | 2008-08-07 | セラヴァンス, インコーポレーテッド | インダゾール−カルボキサミド化合物の結晶型 |
JP5042043B2 (ja) * | 2005-03-02 | 2012-10-03 | セラヴァンス, インコーポレーテッド | 5−ht4レセプターアゴニストであるキノリン化合物 |
TWI377206B (en) * | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
EP1902053B1 (de) * | 2005-06-07 | 2011-01-12 | Theravance, Inc. | Benzimidazoloncarbonsäureamidverbindungen als agonisten des 5-ht4-rezeptors |
MY143574A (en) * | 2005-11-22 | 2011-05-31 | Theravance Inc | Carbamate compounds as 5-ht4 receptor agonists |
US7487406B2 (en) * | 2005-11-29 | 2009-02-03 | International Business Machines Corporation | Systems, methods, and media for managing software defects |
ATE509021T1 (de) * | 2006-02-16 | 2011-05-15 | Theravance Inc | Verfahren zur herstellung von zwischenverbindungen zu 5-ht4-rezeptoragonist- verbindungen |
TWI415850B (zh) | 2007-07-20 | 2013-11-21 | Theravance Inc | 製備mu類鴉片受體拮抗劑之中間物的方法 |
EP2445877B1 (de) | 2008-12-03 | 2014-07-23 | Nanotherapeutics, Inc. | Bicyclische verbindungen und verfahren zu deren herstellung und deren verwendung |
AR079493A1 (es) | 2009-12-21 | 2012-02-01 | Nippon Soda Co | Compuesto de amina ciclica y acaricida |
AR081721A1 (es) | 2010-02-25 | 2012-10-17 | Nippon Soda Co | Compuesto de amina ciclica y acaricida |
WO2011116491A1 (zh) * | 2010-03-22 | 2011-09-29 | 北京世纪迈劲生物科技有限公司 | 制备二苯乙醇酸去甲托品酯和其盐的方法及其中所用的中间体 |
JP5767099B2 (ja) * | 2011-06-16 | 2015-08-19 | 日本曹達株式会社 | 環状アミン化合物および有害生物防除剤 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1228293B (it) * | 1989-02-06 | 1991-06-07 | Angeli Inst Spa | Benzoderivati di composti eterociclici contenenti azoto. |
JP3122671B2 (ja) * | 1990-05-23 | 2001-01-09 | 協和醗酵工業株式会社 | 複素環式化合物 |
EP0564650B1 (de) * | 1990-12-28 | 1995-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Chinolinderivat |
EP0670319A4 (de) * | 1992-11-20 | 1996-01-17 | Thaisho Pharmaceutical Co Ltd | Heterocyclische verbindungen. |
-
1995
- 1995-05-17 JP JP11879495A patent/JP3829879B2/ja not_active Expired - Fee Related
- 1995-05-18 CA CA002167055A patent/CA2167055A1/en not_active Abandoned
- 1995-05-18 US US08/578,532 patent/US5753673A/en not_active Expired - Fee Related
- 1995-05-18 DE DE69534768T patent/DE69534768T2/de not_active Expired - Fee Related
- 1995-05-18 KR KR1019960700086A patent/KR960703907A/ko not_active Application Discontinuation
- 1995-05-18 EP EP95918742A patent/EP0710662B1/de not_active Expired - Lifetime
- 1995-05-18 EP EP99123695A patent/EP1018513B1/de not_active Expired - Lifetime
- 1995-05-18 AT AT95918742T patent/ATE200286T1/de active
- 1995-05-18 AU AU24548/95A patent/AU685632B2/en not_active Ceased
- 1995-05-18 DK DK99123695T patent/DK1018513T3/da active
- 1995-05-18 DE DE69520545T patent/DE69520545T2/de not_active Expired - Fee Related
- 1995-05-18 AT AT99123695T patent/ATE316970T1/de not_active IP Right Cessation
- 1995-05-18 ES ES99123695T patent/ES2252907T3/es not_active Expired - Lifetime
- 1995-05-18 WO PCT/JP1995/000954 patent/WO1995031455A1/ja active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
AU685632B2 (en) | 1998-01-22 |
US5753673A (en) | 1998-05-19 |
DE69520545T2 (de) | 2001-08-09 |
EP1018513A3 (de) | 2004-07-21 |
EP1018513B1 (de) | 2006-02-01 |
DE69520545D1 (de) | 2001-05-10 |
EP0710662A1 (de) | 1996-05-08 |
CA2167055A1 (en) | 1995-11-23 |
JPH0834784A (ja) | 1996-02-06 |
KR960703907A (ko) | 1996-08-31 |
WO1995031455A1 (fr) | 1995-11-23 |
ES2252907T3 (es) | 2006-05-16 |
AU2454895A (en) | 1995-12-05 |
EP0710662A4 (de) | 1996-09-18 |
ATE316970T1 (de) | 2006-02-15 |
EP1018513A2 (de) | 2000-07-12 |
DE69534768D1 (de) | 2006-04-13 |
EP0710662B1 (de) | 2001-04-04 |
JP3829879B2 (ja) | 2006-10-04 |
DE69534768T2 (de) | 2007-02-01 |
DK1018513T3 (da) | 2006-04-03 |
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