ATE194610T1 - Derivate des radicicols - Google Patents

Derivate des radicicols

Info

Publication number
ATE194610T1
ATE194610T1 AT96912263T AT96912263T ATE194610T1 AT E194610 T1 ATE194610 T1 AT E194610T1 AT 96912263 T AT96912263 T AT 96912263T AT 96912263 T AT96912263 T AT 96912263T AT E194610 T1 ATE194610 T1 AT E194610T1
Authority
AT
Austria
Prior art keywords
represents hydrogen
alkenoyl
alkanoyl
radicicol
present
Prior art date
Application number
AT96912263T
Other languages
English (en)
Inventor
Tsutomu Agatsuma
Yutaka Saitoh
Yoshinori Yamashita
Tamio Mizukami
Shiro Akinaga
Katsushige Gomi
Kazuhito Akasaka
Isami Takahashi
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE194610T1 publication Critical patent/ATE194610T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT96912263T 1995-04-26 1996-04-26 Derivate des radicicols ATE194610T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10262695 1995-04-26
PCT/JP1996/001158 WO1996033989A1 (fr) 1995-04-26 1996-04-26 Derives de radicicol

Publications (1)

Publication Number Publication Date
ATE194610T1 true ATE194610T1 (de) 2000-07-15

Family

ID=14332458

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96912263T ATE194610T1 (de) 1995-04-26 1996-04-26 Derivate des radicicols

Country Status (13)

Country Link
US (1) US5977165A (de)
EP (1) EP0823429B1 (de)
JP (1) JP3938936B2 (de)
KR (1) KR19990008051A (de)
AT (1) ATE194610T1 (de)
AU (1) AU700840B2 (de)
CA (1) CA2218981C (de)
DE (1) DE69609325T2 (de)
ES (1) ES2149468T3 (de)
HU (1) HUP9901344A3 (de)
NO (1) NO974890L (de)
NZ (1) NZ311790A (de)
WO (1) WO1996033989A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990076764A (ko) 1996-10-25 1999-10-15 히라타 다다시 래디시콜 유도체
US6353019B1 (en) * 1997-07-25 2002-03-05 United States Of America As Represented By The Department Of Health And Human Services Macrocyclic lactones, compositions, and methods of use
AU3534499A (en) * 1998-04-24 1999-11-16 Kyowa Hakko Kogyo Co. Ltd. Radicicol derivatives
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
US6635671B1 (en) 1998-12-24 2003-10-21 Novation Pharmaceuticals Inc. Compounds which affect mRNA stability and uses therefor
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
BR0112750A (pt) 2000-07-26 2003-09-09 Smithkline Beecham Plc Aminopiperidina quinolinas e seus análogos azaisostéricos com atividade antibacteriana
ATE328888T1 (de) * 2000-08-25 2006-06-15 Sloan Kettering Inst Cancer Radicicol und monocillin und ihre analogen und ihre anwendungen
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
JP2004529188A (ja) * 2001-05-23 2004-09-24 スローン − ケッタリング インスティチュート フォー キャンサー リサーチ 上昇に関連した癌の治療法
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
US20040192638A1 (en) * 2001-07-02 2004-09-30 Oaks John A. Method and composition for prolonging the residence time of drugs in the gut
AU2003239302A1 (en) 2002-01-29 2003-09-02 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
TW200406410A (en) 2002-01-29 2004-05-01 Glaxo Group Ltd Compounds
ES2432747T3 (es) 2003-06-27 2013-12-05 Kyowa Hakko Kirin Co., Ltd. Inhibidores de proteínas de la familia HSP90
EP1666064A4 (de) * 2003-08-22 2008-12-17 Kyowa Hakko Kogyo Kk Mittel zur behandlung von erkrankungen im zusammenhang mit immunoglobulin-gen-translokation
US20080108694A1 (en) * 2003-12-19 2008-05-08 Samuel J Danishefsky Novel Macrocycles and Uses Thereof
CN103539769B (zh) 2006-08-11 2016-03-16 斯特拉斯堡大学 用作激酶抑制剂和hsp90抑制剂的大环化合物
US20110190237A1 (en) * 2008-01-15 2011-08-04 Nexgenix Pharmaceuticals Macrocyclic Prodrug Compounds Useful as Therapeutics
CN101990399B (zh) * 2008-01-15 2016-05-04 斯特拉斯堡大学 用作治疗剂的二羟基苯甲酸内酯的合成
CN102015673B (zh) 2008-02-21 2014-10-29 昂科协同公司 用作治疗剂的大环前药化合物
US10434085B2 (en) 2015-06-04 2019-10-08 University Of North Carolina At Greensboro Non-aromatic difluoro analogues of resorcylic acid lactones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228079A (en) * 1978-10-30 1980-10-14 W. R. Grace & Co. Dialkoxy monorden derivatives
IE911915A1 (en) * 1990-06-06 1991-12-18 Sankyo Co Radicicol derivatives, their preparation and their¹anti-tumor activity
GB9225396D0 (en) * 1992-12-04 1993-01-27 Sandoz Ltd Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
HUP9901344A2 (hu) 2001-04-28
NZ311790A (en) 1999-04-29
AU6292796A (en) 1996-11-18
US5977165A (en) 1999-11-02
WO1996033989A1 (fr) 1996-10-31
KR19990008051A (ko) 1999-01-25
CA2218981C (en) 2007-01-16
EP0823429A1 (de) 1998-02-11
EP0823429A4 (de) 1998-07-08
EP0823429B1 (de) 2000-07-12
DE69609325D1 (de) 2000-08-17
HUP9901344A3 (en) 2001-05-28
JP3938936B2 (ja) 2007-06-27
AU700840B2 (en) 1999-01-14
DE69609325T2 (de) 2000-11-23
NO974890D0 (no) 1997-10-23
ES2149468T3 (es) 2000-11-01
NO974890L (no) 1997-12-29
CA2218981A1 (en) 1996-10-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties