DE69609325T2 - Derivate des radicicols - Google Patents

Derivate des radicicols

Info

Publication number
DE69609325T2
DE69609325T2 DE69609325T DE69609325T DE69609325T2 DE 69609325 T2 DE69609325 T2 DE 69609325T2 DE 69609325 T DE69609325 T DE 69609325T DE 69609325 T DE69609325 T DE 69609325T DE 69609325 T2 DE69609325 T2 DE 69609325T2
Authority
DE
Germany
Prior art keywords
represents hydrogen
alkenoyl
alkanoyl
present
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69609325T
Other languages
English (en)
Other versions
DE69609325D1 (de
Inventor
Tsutomu Agatsuma
Yutaka Saitoh
Yoshinori Yamashita
Tamio Mizukami
Shiro Akinaga
Katsushige Gomi
Kazuhito Akasaka
Isami Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE69609325D1 publication Critical patent/DE69609325D1/de
Publication of DE69609325T2 publication Critical patent/DE69609325T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DE69609325T 1995-04-26 1996-04-26 Derivate des radicicols Expired - Fee Related DE69609325T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10262695 1995-04-26
PCT/JP1996/001158 WO1996033989A1 (fr) 1995-04-26 1996-04-26 Derives de radicicol

Publications (2)

Publication Number Publication Date
DE69609325D1 DE69609325D1 (de) 2000-08-17
DE69609325T2 true DE69609325T2 (de) 2000-11-23

Family

ID=14332458

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69609325T Expired - Fee Related DE69609325T2 (de) 1995-04-26 1996-04-26 Derivate des radicicols

Country Status (13)

Country Link
US (1) US5977165A (de)
EP (1) EP0823429B1 (de)
JP (1) JP3938936B2 (de)
KR (1) KR19990008051A (de)
AT (1) ATE194610T1 (de)
AU (1) AU700840B2 (de)
CA (1) CA2218981C (de)
DE (1) DE69609325T2 (de)
ES (1) ES2149468T3 (de)
HU (1) HUP9901344A3 (de)
NO (1) NO974890L (de)
NZ (1) NZ311790A (de)
WO (1) WO1996033989A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE266017T1 (de) * 1996-10-25 2004-05-15 Kyowa Hakko Kogyo Kk Radicicolderivate
DE69824855T2 (de) * 1997-07-25 2005-08-25 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung
WO1999055689A1 (fr) * 1998-04-24 1999-11-04 Kyowa Hakko Kogyo Co., Ltd. Derives de radicicol
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
US6635671B1 (en) 1998-12-24 2003-10-21 Novation Pharmaceuticals Inc. Compounds which affect mRNA stability and uses therefor
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
DE60125373T2 (de) 2000-07-26 2007-10-18 Smithkline Beecham P.L.C., Brentford Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
EP1315732B1 (de) * 2000-08-25 2006-06-07 Sloan-Kettering Institute For Cancer Research Radicicol und monocillin und ihre analogen und ihre anwendungen
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
WO2002094196A2 (en) * 2001-05-23 2002-11-28 Sloan Kettering Institute For Cancer Research Method of treatment for cancers associated with elevated
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
US20040192638A1 (en) * 2001-07-02 2004-09-30 Oaks John A. Method and composition for prolonging the residence time of drugs in the gut
EP2181996A1 (de) 2002-01-29 2010-05-05 Glaxo Group Limited Aminopiperidinderivate
WO2003064431A2 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
CN100567242C (zh) 2003-06-27 2009-12-09 协和发酵麒麟株式会社 Hsp90家族蛋白质阻断剂
EP1666064A4 (de) * 2003-08-22 2008-12-17 Kyowa Hakko Kogyo Kk Mittel zur behandlung von erkrankungen im zusammenhang mit immunoglobulin-gen-translokation
US20080108694A1 (en) * 2003-12-19 2008-05-08 Samuel J Danishefsky Novel Macrocycles and Uses Thereof
CN103539769B (zh) * 2006-08-11 2016-03-16 斯特拉斯堡大学 用作激酶抑制剂和hsp90抑制剂的大环化合物
WO2009105755A2 (en) 2008-02-21 2009-08-27 Nexgenix Pharmaceuticals Macrocyclic prodrug compounds useful as therapeutics
MX2010007755A (es) * 2008-01-15 2010-12-21 Univ Strasbourg Sintesis de lactonas de acido resorcilico utiles como agentes terapeuticos.
US20110190237A1 (en) * 2008-01-15 2011-08-04 Nexgenix Pharmaceuticals Macrocyclic Prodrug Compounds Useful as Therapeutics
US10434085B2 (en) 2015-06-04 2019-10-08 University Of North Carolina At Greensboro Non-aromatic difluoro analogues of resorcylic acid lactones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228079A (en) * 1978-10-30 1980-10-14 W. R. Grace & Co. Dialkoxy monorden derivatives
KR920000763A (ko) * 1990-06-06 1992-01-29 가와무라 요시부미 라디시콜 유도체, 그 제조방법 및 그의 항종양 활성
GB9225396D0 (en) * 1992-12-04 1993-01-27 Sandoz Ltd Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
EP0823429A1 (de) 1998-02-11
NZ311790A (en) 1999-04-29
CA2218981A1 (en) 1996-10-31
EP0823429B1 (de) 2000-07-12
ES2149468T3 (es) 2000-11-01
NO974890D0 (no) 1997-10-23
ATE194610T1 (de) 2000-07-15
AU700840B2 (en) 1999-01-14
JP3938936B2 (ja) 2007-06-27
AU6292796A (en) 1996-11-18
US5977165A (en) 1999-11-02
HUP9901344A2 (hu) 2001-04-28
CA2218981C (en) 2007-01-16
EP0823429A4 (de) 1998-07-08
DE69609325D1 (de) 2000-08-17
NO974890L (no) 1997-12-29
KR19990008051A (ko) 1999-01-25
HUP9901344A3 (en) 2001-05-28
WO1996033989A1 (fr) 1996-10-31

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee