NO974890L - Radicicolderivater - Google Patents
RadicicolderivaterInfo
- Publication number
- NO974890L NO974890L NO974890A NO974890A NO974890L NO 974890 L NO974890 L NO 974890L NO 974890 A NO974890 A NO 974890A NO 974890 A NO974890 A NO 974890A NO 974890 L NO974890 L NO 974890L
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen
- alkenoyl
- alkanoyl
- same
- derivatives
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- AECPBJMOGBFQDN-YMYQVXQQSA-N radicicol Chemical class C1CCCC(=O)C[C@H]2[C@H](Cl)C(=O)CC(=O)[C@H]2C(=O)O[C@H](C)C[C@H]2O[C@@H]21 AECPBJMOGBFQDN-YMYQVXQQSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001981 tert-butyldimethylsilyl group Chemical group [H]C([H])([H])[Si]([H])(C([H])([H])[H])[*]C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Flanged Joints, Insulating Joints, And Other Joints (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10262695 | 1995-04-26 | ||
| PCT/JP1996/001158 WO1996033989A1 (fr) | 1995-04-26 | 1996-04-26 | Derives de radicicol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO974890D0 NO974890D0 (no) | 1997-10-23 |
| NO974890L true NO974890L (no) | 1997-12-29 |
Family
ID=14332458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO974890A NO974890L (no) | 1995-04-26 | 1997-10-23 | Radicicolderivater |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5977165A (de) |
| EP (1) | EP0823429B1 (de) |
| JP (1) | JP3938936B2 (de) |
| KR (1) | KR19990008051A (de) |
| AT (1) | ATE194610T1 (de) |
| AU (1) | AU700840B2 (de) |
| CA (1) | CA2218981C (de) |
| DE (1) | DE69609325T2 (de) |
| ES (1) | ES2149468T3 (de) |
| HU (1) | HUP9901344A3 (de) |
| NO (1) | NO974890L (de) |
| NZ (1) | NZ311790A (de) |
| WO (1) | WO1996033989A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2216130T3 (es) | 1996-10-25 | 2004-10-16 | Kyowa Hakko Kogyo Co., Ltd. | Derivados de radicicol. |
| DE69824855T2 (de) * | 1997-07-25 | 2005-08-25 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung |
| AU3534499A (en) * | 1998-04-24 | 1999-11-16 | Kyowa Hakko Kogyo Co. Ltd. | Radicicol derivatives |
| GB9822450D0 (en) * | 1998-10-14 | 1998-12-09 | Smithkline Beecham Plc | Medicaments |
| CA2356622A1 (en) | 1998-12-24 | 2000-07-06 | Novation Pharmaceuticals Inc. | Compounds which affect mrna stability and uses therefor |
| GB9914486D0 (en) | 1999-06-21 | 1999-08-18 | Smithkline Beecham Plc | Medicaments |
| GB9917408D0 (en) | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
| GB9917406D0 (en) | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
| ES2278778T3 (es) | 2000-07-26 | 2007-08-16 | Smithkline Beecham Plc | Aminopiperidin quinolinas y sus analogos azaisostericos con actividad antibacteriana. |
| WO2002016369A2 (en) * | 2000-08-25 | 2002-02-28 | Sloan-Kettering Institute For Cancer Research | Novel macrocycles and uses thereof |
| GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| CA2447066A1 (en) * | 2001-05-23 | 2002-11-28 | Sloan Kettering Institute For Cancer Research | Method of treatment for cancers associated with elevated |
| GB0112834D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0112836D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| US20040192638A1 (en) * | 2001-07-02 | 2004-09-30 | Oaks John A. | Method and composition for prolonging the residence time of drugs in the gut |
| AR038240A1 (es) | 2002-01-29 | 2005-01-05 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para su preparacion |
| EP1470131A2 (de) | 2002-01-29 | 2004-10-27 | Glaxo Group Limited | "aminopiperidinverbindugen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen " |
| CN100567242C (zh) | 2003-06-27 | 2009-12-09 | 协和发酵麒麟株式会社 | Hsp90家族蛋白质阻断剂 |
| US20070004674A1 (en) * | 2003-08-22 | 2007-01-04 | Kyowa Hakko Kogyo Co. Ltd. | Remedy for diseases associated with immunoglobulin gene translocation |
| WO2005061481A1 (en) * | 2003-12-19 | 2005-07-07 | Sloan-Kettering Institute For Cancer Research | Novel ma crocycles and uses thereof |
| CN103539769B (zh) * | 2006-08-11 | 2016-03-16 | 斯特拉斯堡大学 | 用作激酶抑制剂和hsp90抑制剂的大环化合物 |
| US20110190237A1 (en) * | 2008-01-15 | 2011-08-04 | Nexgenix Pharmaceuticals | Macrocyclic Prodrug Compounds Useful as Therapeutics |
| KR20160017105A (ko) * | 2008-01-15 | 2016-02-15 | 유니베르시떼 드 스트라스부르 | 치료제로서 유용한 레조르실산 락톤의 합성 |
| JP5935055B2 (ja) | 2008-02-21 | 2016-06-15 | オンコシナジー・インコーポレイテッド | 治療薬として有用な大環状プロドラッグ化合物 |
| WO2016196256A2 (en) | 2015-06-04 | 2016-12-08 | University Of North Carolina At Greensboro | Non-aromatic difluoro analogues of resorcylic acid lactones |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4228079A (en) * | 1978-10-30 | 1980-10-14 | W. R. Grace & Co. | Dialkoxy monorden derivatives |
| KR920000763A (ko) * | 1990-06-06 | 1992-01-29 | 가와무라 요시부미 | 라디시콜 유도체, 그 제조방법 및 그의 항종양 활성 |
| GB9225396D0 (en) * | 1992-12-04 | 1993-01-27 | Sandoz Ltd | Improvements in or relating to organic compounds |
-
1996
- 1996-04-26 WO PCT/JP1996/001158 patent/WO1996033989A1/ja not_active Application Discontinuation
- 1996-04-26 CA CA002218981A patent/CA2218981C/en not_active Expired - Fee Related
- 1996-04-26 AT AT96912263T patent/ATE194610T1/de not_active IP Right Cessation
- 1996-04-26 ES ES96912263T patent/ES2149468T3/es not_active Expired - Lifetime
- 1996-04-26 AU AU62927/96A patent/AU700840B2/en not_active Ceased
- 1996-04-26 DE DE69609325T patent/DE69609325T2/de not_active Expired - Fee Related
- 1996-04-26 JP JP53237396A patent/JP3938936B2/ja not_active Expired - Fee Related
- 1996-04-26 EP EP96912263A patent/EP0823429B1/de not_active Expired - Lifetime
- 1996-04-26 NZ NZ311790A patent/NZ311790A/en unknown
- 1996-04-26 KR KR1019970707575A patent/KR19990008051A/ko not_active Application Discontinuation
- 1996-04-26 HU HU9901344A patent/HUP9901344A3/hu unknown
-
1997
- 1997-10-23 NO NO974890A patent/NO974890L/no not_active Application Discontinuation
- 1997-10-27 US US08/958,285 patent/US5977165A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996033989A1 (fr) | 1996-10-31 |
| EP0823429B1 (de) | 2000-07-12 |
| JP3938936B2 (ja) | 2007-06-27 |
| HUP9901344A3 (en) | 2001-05-28 |
| DE69609325T2 (de) | 2000-11-23 |
| ATE194610T1 (de) | 2000-07-15 |
| HUP9901344A2 (hu) | 2001-04-28 |
| CA2218981A1 (en) | 1996-10-31 |
| NO974890D0 (no) | 1997-10-23 |
| NZ311790A (en) | 1999-04-29 |
| US5977165A (en) | 1999-11-02 |
| DE69609325D1 (de) | 2000-08-17 |
| KR19990008051A (ko) | 1999-01-25 |
| CA2218981C (en) | 2007-01-16 |
| EP0823429A4 (de) | 1998-07-08 |
| EP0823429A1 (de) | 1998-02-11 |
| AU6292796A (en) | 1996-11-18 |
| ES2149468T3 (es) | 2000-11-01 |
| AU700840B2 (en) | 1999-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |