ATE191473T1 - 2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung - Google Patents
2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendungInfo
- Publication number
- ATE191473T1 ATE191473T1 AT96939987T AT96939987T ATE191473T1 AT E191473 T1 ATE191473 T1 AT E191473T1 AT 96939987 T AT96939987 T AT 96939987T AT 96939987 T AT96939987 T AT 96939987T AT E191473 T1 ATE191473 T1 AT E191473T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- pct
- hydroxyanilide
- trimethyl
- theraoeutic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9514086A FR2741619B1 (fr) | 1995-11-28 | 1995-11-28 | Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique |
| PCT/FR1996/001877 WO1997019918A1 (fr) | 1995-11-28 | 1996-11-27 | Nouveaux derives de 2,3,5 trimethyl-4-hydroxy anilides, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE191473T1 true ATE191473T1 (de) | 2000-04-15 |
Family
ID=9484963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96939987T ATE191473T1 (de) | 1995-11-28 | 1996-11-27 | 2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5990173A (de) |
| EP (1) | EP0874812B1 (de) |
| JP (1) | JP2000500771A (de) |
| KR (1) | KR100417275B1 (de) |
| CN (1) | CN1072645C (de) |
| AT (1) | ATE191473T1 (de) |
| AU (1) | AU701186B2 (de) |
| BR (1) | BR9611790A (de) |
| CA (1) | CA2238845C (de) |
| DE (1) | DE69607650T2 (de) |
| DK (1) | DK0874812T3 (de) |
| ES (1) | ES2147399T3 (de) |
| FR (1) | FR2741619B1 (de) |
| GR (1) | GR3033786T3 (de) |
| MX (1) | MX9804226A (de) |
| NZ (1) | NZ322959A (de) |
| PT (1) | PT874812E (de) |
| WO (1) | WO1997019918A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2823207B1 (fr) * | 2001-04-10 | 2004-12-03 | Pf Medicament | Complexes d'anilides a chaine polycarbonee et de cyclodestrines, leur preparation et leur application en tant que medicamment en particulier pour le traitement des dislipidemies |
| WO2003020315A1 (fr) * | 2001-08-28 | 2003-03-13 | Sankyo Company, Limited | Compositions medicinales contenant un antagoniste du recepteur d'angiotensine ii |
| FR2830761B1 (fr) * | 2001-10-12 | 2003-12-12 | Pf Medicament | Procede de preparation d'un compose d'interaction d'un derive anilide avec un support poreux par fluide supercritique |
| FR2830760B1 (fr) * | 2001-10-12 | 2004-06-04 | Pf Medicament | Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique |
| US20050119314A1 (en) * | 2002-04-05 | 2005-06-02 | Sankyo Company, Limited | Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent |
| FR2845991B1 (fr) * | 2002-10-16 | 2005-02-04 | Pf Medicament | Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine |
| EP1600438A4 (de) * | 2003-02-28 | 2007-05-02 | Kaneka Corp | Verfahren zur herstellung optisch aktiver verbindungen mit substituenten in der 2-stellung |
| FR2854079B1 (fr) | 2003-04-25 | 2007-11-30 | Pf Medicament | Procede de preparation de complexes moleculaires |
| KR20110117731A (ko) | 2003-05-30 | 2011-10-27 | 랜박시 래보러터리스 리미티드 | 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도 |
| WO2005051298A2 (en) | 2003-11-19 | 2005-06-09 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
| NZ555325A (en) * | 2004-10-27 | 2009-07-31 | Daiichi Sankyo Co Ltd | Benzene compound having 2 or more substituents |
| AU2006313430B2 (en) | 2005-11-08 | 2012-09-06 | Ranbaxy Laboratories Limited | Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
| FR2918889B1 (fr) * | 2007-07-19 | 2009-10-23 | Galderma Res & Dev | Utilisation de l'eflucimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal |
| US8741966B2 (en) | 2007-11-09 | 2014-06-03 | Pronova Biopharma Norge As | Lipid compounds for use in cosmetic products, as food supplement or as a medicament |
| CN101450911B (zh) * | 2007-11-30 | 2012-02-29 | 山东轩竹医药科技有限公司 | 被金刚烷取代的苯甲酸衍生物 |
| EP2147910A1 (de) * | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Neue Lipid-Verbindungen |
| US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
| MX366137B (es) | 2009-05-08 | 2019-06-28 | Pronova Biopharma Norge As | Acidos grasos poliinsaturados para el tratamiento de trastornos relacionados a las areas de los trastornos cardiovasculares, metabolicos e inflamatorios. |
| EP2248798A1 (de) * | 2009-05-08 | 2010-11-10 | Pronova BioPharma Norge AS | Neue Lipidverbindungen |
| MX350720B (es) | 2010-11-05 | 2017-09-14 | Pronova Biopharma Norge As | Metodos de tratamiento usando compuestos lipidos. |
| FR2973374B1 (fr) * | 2011-04-04 | 2013-08-23 | Pf Medicament | Nouveaux alkylthioethers, leur preparation et leur application en therapeutique |
| EP2961384B1 (de) | 2013-02-28 | 2019-08-28 | Basf As | Zusammensetzung mit einer lipidverbindung, einem triglycerid und einem tensid sowie verfahren zur verwendung davon |
| JP6784696B2 (ja) | 2015-04-28 | 2020-11-11 | プロノヴァ バイオファーマ ノルゲ エーエス | 硫黄を含有する構造的に強化された脂肪酸の非アルコール性脂肪性肝炎の予防及び／又は治療のための使用 |
| US11925614B2 (en) | 2017-12-06 | 2024-03-12 | Basf As | Fatty acid derivatives for treating non-alcoholic steatohepatitis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6040898A (ja) * | 1983-03-31 | 1985-03-04 | Suzuki Shiyoukan:Kk | 真空断熱容器或は貯蔵の製作方法 |
| WO1992009572A1 (fr) * | 1990-11-26 | 1992-06-11 | Taisho Pharmaceutical Co., Ltd. | Derive d'anilide |
| FR2673625B1 (fr) * | 1991-03-08 | 1993-05-07 | Adir | Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO1993013086A1 (en) * | 1991-12-25 | 1993-07-08 | Taisho Pharmaceutical Co., Ltd. | Anilide derivative |
| JP2842147B2 (ja) * | 1992-05-26 | 1998-12-24 | 大正製薬株式会社 | Ａｃａｔ阻害剤 |
-
1995
- 1995-11-28 FR FR9514086A patent/FR2741619B1/fr not_active Expired - Fee Related
-
1996
- 1996-11-27 AT AT96939987T patent/ATE191473T1/de not_active IP Right Cessation
- 1996-11-27 EP EP96939987A patent/EP0874812B1/de not_active Expired - Lifetime
- 1996-11-27 CN CN96199274A patent/CN1072645C/zh not_active Expired - Fee Related
- 1996-11-27 BR BR9611790A patent/BR9611790A/pt not_active IP Right Cessation
- 1996-11-27 ES ES96939987T patent/ES2147399T3/es not_active Expired - Lifetime
- 1996-11-27 DE DE69607650T patent/DE69607650T2/de not_active Expired - Fee Related
- 1996-11-27 WO PCT/FR1996/001877 patent/WO1997019918A1/fr active IP Right Grant
- 1996-11-27 US US09/077,420 patent/US5990173A/en not_active Expired - Lifetime
- 1996-11-27 CA CA002238845A patent/CA2238845C/fr not_active Expired - Fee Related
- 1996-11-27 AU AU77000/96A patent/AU701186B2/en not_active Ceased
- 1996-11-27 KR KR10-1998-0703955A patent/KR100417275B1/ko not_active IP Right Cessation
- 1996-11-27 NZ NZ322959A patent/NZ322959A/en unknown
- 1996-11-27 JP JP9520230A patent/JP2000500771A/ja active Pending
- 1996-11-27 PT PT96939987T patent/PT874812E/pt unknown
- 1996-11-27 DK DK96939987T patent/DK0874812T3/da active
-
1998
- 1998-05-27 MX MX9804226A patent/MX9804226A/es unknown
-
2000
- 2000-06-27 GR GR20000401485T patent/GR3033786T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990071679A (ko) | 1999-09-27 |
| BR9611790A (pt) | 1999-07-13 |
| FR2741619A1 (fr) | 1997-05-30 |
| WO1997019918A1 (fr) | 1997-06-05 |
| EP0874812B1 (de) | 2000-04-05 |
| KR100417275B1 (ko) | 2004-05-20 |
| US5990173A (en) | 1999-11-23 |
| GR3033786T3 (en) | 2000-10-31 |
| CA2238845A1 (fr) | 1997-06-05 |
| AU7700096A (en) | 1997-06-19 |
| DE69607650D1 (de) | 2000-05-11 |
| EP0874812A1 (de) | 1998-11-04 |
| PT874812E (pt) | 2000-09-29 |
| MX9804226A (es) | 1998-09-30 |
| AU701186B2 (en) | 1999-01-21 |
| DK0874812T3 (da) | 2000-09-11 |
| CA2238845C (fr) | 2006-08-29 |
| CN1205689A (zh) | 1999-01-20 |
| ES2147399T3 (es) | 2000-09-01 |
| FR2741619B1 (fr) | 1998-02-13 |
| NZ322959A (en) | 2001-05-25 |
| CN1072645C (zh) | 2001-10-10 |
| JP2000500771A (ja) | 2000-01-25 |
| DE69607650T2 (de) | 2000-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |