ATE191473T1 - 2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung - Google Patents
2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendungInfo
- Publication number
- ATE191473T1 ATE191473T1 AT96939987T AT96939987T ATE191473T1 AT E191473 T1 ATE191473 T1 AT E191473T1 AT 96939987 T AT96939987 T AT 96939987T AT 96939987 T AT96939987 T AT 96939987T AT E191473 T1 ATE191473 T1 AT E191473T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- pct
- hydroxyanilide
- trimethyl
- theraoeutic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9514086A FR2741619B1 (fr) | 1995-11-28 | 1995-11-28 | Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique |
| PCT/FR1996/001877 WO1997019918A1 (fr) | 1995-11-28 | 1996-11-27 | Nouveaux derives de 2,3,5 trimethyl-4-hydroxy anilides, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE191473T1 true ATE191473T1 (de) | 2000-04-15 |
Family
ID=9484963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96939987T ATE191473T1 (de) | 1995-11-28 | 1996-11-27 | 2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5990173A (de) |
| EP (1) | EP0874812B1 (de) |
| JP (1) | JP2000500771A (de) |
| KR (1) | KR100417275B1 (de) |
| CN (1) | CN1072645C (de) |
| AT (1) | ATE191473T1 (de) |
| AU (1) | AU701186B2 (de) |
| BR (1) | BR9611790A (de) |
| CA (1) | CA2238845C (de) |
| DE (1) | DE69607650T2 (de) |
| DK (1) | DK0874812T3 (de) |
| ES (1) | ES2147399T3 (de) |
| FR (1) | FR2741619B1 (de) |
| GR (1) | GR3033786T3 (de) |
| MX (1) | MX9804226A (de) |
| NZ (1) | NZ322959A (de) |
| PT (1) | PT874812E (de) |
| WO (1) | WO1997019918A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2823207B1 (fr) | 2001-04-10 | 2004-12-03 | Pf Medicament | Complexes d'anilides a chaine polycarbonee et de cyclodestrines, leur preparation et leur application en tant que medicamment en particulier pour le traitement des dislipidemies |
| WO2003020315A1 (fr) * | 2001-08-28 | 2003-03-13 | Sankyo Company, Limited | Compositions medicinales contenant un antagoniste du recepteur d'angiotensine ii |
| FR2830760B1 (fr) * | 2001-10-12 | 2004-06-04 | Pf Medicament | Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique |
| FR2830761B1 (fr) * | 2001-10-12 | 2003-12-12 | Pf Medicament | Procede de preparation d'un compose d'interaction d'un derive anilide avec un support poreux par fluide supercritique |
| US20050119314A1 (en) * | 2002-04-05 | 2005-06-02 | Sankyo Company, Limited | Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent |
| FR2845991B1 (fr) * | 2002-10-16 | 2005-02-04 | Pf Medicament | Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine |
| JPWO2004076404A1 (ja) * | 2003-02-28 | 2006-06-01 | 株式会社カネカ | ２位に置換基を有する光学活性化合物の製造法 |
| FR2854079B1 (fr) | 2003-04-25 | 2007-11-30 | Pf Medicament | Procede de preparation de complexes moleculaires |
| WO2004106299A2 (en) | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives and their use as hmg-co inhibitors |
| EP2428516A1 (de) | 2003-11-19 | 2012-03-14 | Metabasis Therapeutics, Inc. | Neue Phosphor enthaltende Thyromimetika |
| RU2007115900A (ru) * | 2004-10-27 | 2008-11-10 | Дайити Санкио Компани, Лимитед (Jp) | Производные бензола, имеющие 2 или более заместителей |
| KR101329112B1 (ko) | 2005-11-08 | 2013-11-14 | 랜박시 래보러터리스 리미티드 | (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법 |
| FR2918889B1 (fr) * | 2007-07-19 | 2009-10-23 | Galderma Res & Dev | Utilisation de l'eflucimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal |
| US8741966B2 (en) | 2007-11-09 | 2014-06-03 | Pronova Biopharma Norge As | Lipid compounds for use in cosmetic products, as food supplement or as a medicament |
| CN101450911B (zh) * | 2007-11-30 | 2012-02-29 | 山东轩竹医药科技有限公司 | 被金刚烷取代的苯甲酸衍生物 |
| EP2147910A1 (de) * | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Neue Lipid-Verbindungen |
| WO2010093601A1 (en) | 2009-02-10 | 2010-08-19 | Metabasis Therapeutics, Inc. | Novel sulfonic acid-containing thyromimetics, and methods for their use |
| AU2010244136B2 (en) | 2009-05-08 | 2016-05-12 | Pronova Biopharma Norge As | Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas |
| EP2248798A1 (de) * | 2009-05-08 | 2010-11-10 | Pronova BioPharma Norge AS | Neue Lipidverbindungen |
| JP2014505017A (ja) | 2010-11-05 | 2014-02-27 | プロノヴァ・バイオファーマ・ノルゲ・アーエス | 脂質化合物を用いる処置方法 |
| FR2973374B1 (fr) * | 2011-04-04 | 2013-08-23 | Pf Medicament | Nouveaux alkylthioethers, leur preparation et leur application en therapeutique |
| JP6537980B2 (ja) | 2013-02-28 | 2019-07-03 | プロノヴァ・バイオファーマ・ノルゲ・アーエスＰｒｏｎｏｖａ ＢｉｏＰｈａｒｍａ Ｎｏｒｇｅ ＡＳ | 脂質化合物、トリグリセリドおよび界面活性剤を含む組成物、ならびにその使用方法 |
| CN115025079A (zh) | 2015-04-28 | 2022-09-09 | 普罗诺瓦生物医药挪威公司 | 结构增强的含硫脂肪酸在预防和/或治疗非酒精性脂肪性肝炎中的用途 |
| WO2019111048A1 (en) | 2017-12-06 | 2019-06-13 | Basf As | Fatty acid derivatives for treating non-alcoholic steatohepatitis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6040898A (ja) * | 1983-03-31 | 1985-03-04 | Suzuki Shiyoukan:Kk | 真空断熱容器或は貯蔵の製作方法 |
| CA2096970C (en) * | 1990-11-26 | 1998-07-14 | Masakazu Sato | Anilide derivative |
| FR2673625B1 (fr) * | 1991-03-08 | 1993-05-07 | Adir | Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5416212A (en) * | 1991-12-25 | 1995-05-16 | Taisho Pharmaceutical Co., Ltd. | Anilide derivatives |
| JP2842147B2 (ja) * | 1992-05-26 | 1998-12-24 | 大正製薬株式会社 | Ａｃａｔ阻害剤 |
-
1995
- 1995-11-28 FR FR9514086A patent/FR2741619B1/fr not_active Expired - Fee Related
-
1996
- 1996-11-27 CN CN96199274A patent/CN1072645C/zh not_active Expired - Fee Related
- 1996-11-27 DE DE69607650T patent/DE69607650T2/de not_active Expired - Fee Related
- 1996-11-27 KR KR10-1998-0703955A patent/KR100417275B1/ko not_active IP Right Cessation
- 1996-11-27 WO PCT/FR1996/001877 patent/WO1997019918A1/fr active IP Right Grant
- 1996-11-27 ES ES96939987T patent/ES2147399T3/es not_active Expired - Lifetime
- 1996-11-27 DK DK96939987T patent/DK0874812T3/da active
- 1996-11-27 CA CA002238845A patent/CA2238845C/fr not_active Expired - Fee Related
- 1996-11-27 NZ NZ322959A patent/NZ322959A/en unknown
- 1996-11-27 EP EP96939987A patent/EP0874812B1/de not_active Expired - Lifetime
- 1996-11-27 US US09/077,420 patent/US5990173A/en not_active Expired - Lifetime
- 1996-11-27 AU AU77000/96A patent/AU701186B2/en not_active Ceased
- 1996-11-27 PT PT96939987T patent/PT874812E/pt unknown
- 1996-11-27 BR BR9611790A patent/BR9611790A/pt not_active IP Right Cessation
- 1996-11-27 JP JP9520230A patent/JP2000500771A/ja active Pending
- 1996-11-27 AT AT96939987T patent/ATE191473T1/de not_active IP Right Cessation
-
1998
- 1998-05-27 MX MX9804226A patent/MX9804226A/es unknown
-
2000
- 2000-06-27 GR GR20000401485T patent/GR3033786T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3033786T3 (en) | 2000-10-31 |
| DK0874812T3 (da) | 2000-09-11 |
| US5990173A (en) | 1999-11-23 |
| PT874812E (pt) | 2000-09-29 |
| KR19990071679A (ko) | 1999-09-27 |
| FR2741619A1 (fr) | 1997-05-30 |
| CA2238845C (fr) | 2006-08-29 |
| NZ322959A (en) | 2001-05-25 |
| AU7700096A (en) | 1997-06-19 |
| EP0874812B1 (de) | 2000-04-05 |
| CN1205689A (zh) | 1999-01-20 |
| MX9804226A (es) | 1998-09-30 |
| WO1997019918A1 (fr) | 1997-06-05 |
| AU701186B2 (en) | 1999-01-21 |
| JP2000500771A (ja) | 2000-01-25 |
| ES2147399T3 (es) | 2000-09-01 |
| FR2741619B1 (fr) | 1998-02-13 |
| DE69607650D1 (de) | 2000-05-11 |
| CN1072645C (zh) | 2001-10-10 |
| BR9611790A (pt) | 1999-07-13 |
| CA2238845A1 (fr) | 1997-06-05 |
| EP0874812A1 (de) | 1998-11-04 |
| DE69607650T2 (de) | 2000-11-30 |
| KR100417275B1 (ko) | 2004-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |