ATE191237T1 - Verfahren zur immobilisierung von nukleinsäuresonden an polystyroloberflächen - Google Patents
Verfahren zur immobilisierung von nukleinsäuresonden an polystyroloberflächenInfo
- Publication number
- ATE191237T1 ATE191237T1 AT93902855T AT93902855T ATE191237T1 AT E191237 T1 ATE191237 T1 AT E191237T1 AT 93902855 T AT93902855 T AT 93902855T AT 93902855 T AT93902855 T AT 93902855T AT E191237 T1 ATE191237 T1 AT E191237T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- polystyrene surfaces
- acid probe
- base
- immobilizing nucleic
- Prior art date
Links
- 108020004711 Nucleic Acid Probes Proteins 0.000 title abstract 2
- 239000004793 Polystyrene Substances 0.000 title abstract 2
- 239000002853 nucleic acid probe Substances 0.000 title abstract 2
- 229920002223 polystyrene Polymers 0.000 title abstract 2
- 230000003100 immobilizing effect Effects 0.000 title 1
- 238000003556 assay Methods 0.000 abstract 2
- 238000009396 hybridization Methods 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000004544 DNA amplification Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/813,338 US5747244A (en) | 1991-12-23 | 1991-12-23 | Nucleic acid probes immobilized on polystyrene surfaces |
| PCT/US1992/011343 WO1993013224A1 (en) | 1991-12-23 | 1992-12-22 | Process for immobilizing nucleic acid probes on polystyrene surfaces |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE191237T1 true ATE191237T1 (de) | 2000-04-15 |
Family
ID=25212094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93902855T ATE191237T1 (de) | 1991-12-23 | 1992-12-22 | Verfahren zur immobilisierung von nukleinsäuresonden an polystyroloberflächen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5747244A (de) |
| EP (1) | EP0620864B1 (de) |
| JP (2) | JP3515781B2 (de) |
| AT (1) | ATE191237T1 (de) |
| AU (1) | AU3427693A (de) |
| CA (1) | CA2125145A1 (de) |
| DE (1) | DE69230864T2 (de) |
| WO (1) | WO1993013224A1 (de) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100361933B1 (ko) * | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US6821727B1 (en) | 1993-11-15 | 2004-11-23 | Applera Corporation | Hybridization assay using self-quenching fluorescence probe |
| US5853974A (en) | 1995-06-07 | 1998-12-29 | Chiron Corporation | Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates |
| US7825237B2 (en) | 1996-05-03 | 2010-11-02 | Applied Biosystems, Llc | Oligonucleotides and analogs labeled with energy transfer dyes |
| US5945526A (en) | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5800996A (en) * | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US5863727A (en) * | 1996-05-03 | 1999-01-26 | The Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US7388092B2 (en) | 1996-05-03 | 2008-06-17 | Applera Corporation | Oligonucleotides and analogs labeled with energy transfer dyes |
| US5837466A (en) * | 1996-12-16 | 1998-11-17 | Vysis, Inc. | Devices and methods for detecting nucleic acid analytes in samples |
| US5958696A (en) * | 1997-07-17 | 1999-09-28 | Boehringer Ingelheim Pharmaceuticals, Inc. | Quantitative solid phase helicase assay |
| PT1038022E (pt) * | 1997-12-12 | 2005-11-30 | Digene Corp | Avaliacao de doencas relacionadas com o virus papiloma humano |
| WO1999042620A2 (en) * | 1998-02-19 | 1999-08-26 | Edvotek | Articles of manufacture and methods for staining biomolecules |
| US6458953B1 (en) * | 1998-12-09 | 2002-10-01 | La Jolla Pharmaceutical Company | Valency platform molecules comprising carbamate linkages |
| US6638714B1 (en) * | 1999-02-03 | 2003-10-28 | Ortho-Clinical Diagnostics, Inc. | Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof |
| US6623919B1 (en) * | 1999-02-03 | 2003-09-23 | Ortho-Clinical Diagnostics, Inc | Oligonucleotide primers for efficient multiplex detection of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) and methods of use thereof |
| CN1762990A (zh) * | 1999-06-08 | 2006-04-26 | 拉卓拉药物公司 | 包含氨基氧基的化合价平台分子 |
| US6218124B1 (en) | 1999-08-27 | 2001-04-17 | Pe Corporation | Method for detecting oligonucleotides using UV light source |
| AU7078200A (en) * | 1999-08-27 | 2001-03-26 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Polypeptides, comprising il-6 ligand-binding receptor domains and related nucleic acids, antibodies, compositions, and methods of use |
| US6358684B1 (en) | 1999-08-27 | 2002-03-19 | Pe Corporation | UV excitable fluorescent energy transfer dyes |
| US6503736B1 (en) * | 1999-11-12 | 2003-01-07 | BIOMéRIEUX, INC. | Antibodies to crosslinkers and methods for using the same |
| US7109024B2 (en) * | 1999-11-15 | 2006-09-19 | Dr. Chip Biotechnology Inc. | Biomolecule-bound substrates |
| US20040146918A1 (en) * | 2000-02-18 | 2004-07-29 | Weiner Michael L. | Hybrid nucleic acid assembly |
| AU2001249674A1 (en) * | 2000-03-29 | 2001-10-08 | Polyprobe, Inc. | Quality control reagents for nucleic acid microarrays |
| CN1434726A (zh) * | 2000-06-08 | 2003-08-06 | 拉卓拉药物公司 | 包含高分子量聚环氧乙烷的多价平台分子 |
| US7601497B2 (en) * | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7439016B1 (en) | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US6890483B2 (en) * | 2000-07-05 | 2005-05-10 | Cuno Incorporated | Non-luminescent substrate |
| JP2004502928A (ja) * | 2000-07-05 | 2004-01-29 | キュノ、インコーポレーテッド | 微量分析の識別適用のための改良された低蛍光のナイロン/ガラス複合体 |
| US20030219816A1 (en) * | 2001-07-02 | 2003-11-27 | Keith Solomon | Composite microarray slides |
| GB0016836D0 (en) * | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (1) |
| EP1360323A4 (de) * | 2000-09-20 | 2007-07-18 | Datascope Investment Corp | Nukleinsäurenachweis durch dendrimermarkierung |
| JP2002125688A (ja) * | 2000-10-30 | 2002-05-08 | Tosoh Corp | C型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法 |
| US8964604B2 (en) * | 2000-12-26 | 2015-02-24 | Polycom, Inc. | Conference endpoint instructing conference bridge to dial phone number |
| US6927029B2 (en) | 2001-12-03 | 2005-08-09 | Agilent Technologies, Inc. | Surface with tethered polymeric species for binding biomolecules |
| JP2005521410A (ja) * | 2002-03-29 | 2005-07-21 | ジェネンテック・インコーポレーテッド | 核酸分析試料の検出と定量化のための方法及び組成物 |
| DE60211685T2 (de) * | 2002-08-02 | 2007-05-10 | Sony Deutschland Gmbh | Verfahren zur Bindung hydophiler Substanzen an hydrophile Makromoleküle und Immobilisierung derselben auf hydrophoben Oberflächen |
| WO2004015075A2 (en) * | 2002-08-08 | 2004-02-19 | Dharmacon, Inc. | Short interfering rnas having a hairpin structure containing a non-nucleotide loop |
| US20040043478A1 (en) * | 2002-08-29 | 2004-03-04 | Li-Wei Hsu | Plastic slides for the fabrication of biochips |
| JP4824312B2 (ja) * | 2002-11-26 | 2011-11-30 | ユニバーシティ オブ ユタ リサーチ ファンデーション | 微小孔物質、被分析物の局在化及び定量の方法、並びに被分析物の局在化及び定量用物品 |
| US7597936B2 (en) * | 2002-11-26 | 2009-10-06 | University Of Utah Research Foundation | Method of producing a pigmented composite microporous material |
| US7833714B1 (en) | 2003-04-11 | 2010-11-16 | Affymetrix, Inc. | Combinatorial affinity selection |
| JP5173193B2 (ja) * | 2003-11-14 | 2013-03-27 | スリーエム イノベイティブ プロパティズ カンパニー | N−スルホニルアミノカルボニル含有化合物 |
| US7943388B2 (en) * | 2003-11-14 | 2011-05-17 | 3M Innovative Properties Company | Acoustic sensors and methods |
| US7361767B2 (en) * | 2003-11-14 | 2008-04-22 | 3M Innovative Properties Company | N-sulfonyldicarboximide containing tethering compounds |
| US7169933B2 (en) * | 2003-11-14 | 2007-01-30 | 3M Innovative Properties Company | N-sulfonylaminocarbonyl containing compounds |
| US7423155B2 (en) * | 2003-11-14 | 2008-09-09 | 3M Innovative Properties Company | N-sulfonyldicarboximide containing tethering compounds |
| US7482122B1 (en) * | 2004-10-19 | 2009-01-27 | Hai Xing Chen | Method of signal enhancement for measurement of nucleic acid sequences |
| US20060147940A1 (en) * | 2004-12-30 | 2006-07-06 | Affymetrix, Inc. | Combinatorial affinity selection |
| US8632970B2 (en) | 2005-05-09 | 2014-01-21 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| EP1880206B1 (de) * | 2005-05-09 | 2012-11-14 | Affymetrix, Inc. | Multiplex-einfang von nukleinsäuren |
| WO2006124771A2 (en) | 2005-05-12 | 2006-11-23 | Panomics, Inc. | Multiplex branched-chain dna assays |
| US20080038725A1 (en) | 2005-06-20 | 2008-02-14 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| US7544756B2 (en) * | 2005-09-30 | 2009-06-09 | 3M Innovative Properties Company | Crosslinked polymers with amine binding groups |
| US7544754B2 (en) | 2005-09-30 | 2009-06-09 | 3M Innovative Properties Company | Crosslinked polymers with amine binding groups |
| US7927798B2 (en) * | 2005-10-05 | 2011-04-19 | Panomics, Inc. | Detection of nucleic acids from whole blood |
| EP1951905B1 (de) | 2005-11-10 | 2012-04-11 | Affymetrix, Inc. | Nachweis von nukleinsäuren über amplifikation von stellvertreternukleinsäuren |
| JP2008043332A (ja) | 2006-08-17 | 2008-02-28 | Panomics Inc | 組織スライドからの核酸定量 |
| US7492312B2 (en) * | 2006-11-14 | 2009-02-17 | Fam Adly T | Multiplicative mismatched filters for optimum range sidelobe suppression in barker code reception |
| US8080372B2 (en) * | 2007-04-11 | 2011-12-20 | Canon Kabushiki Kaisha | Method for detecting nucleic acid in sample, method for designing probes, system for designing probes therefor |
| EP2511708B1 (de) | 2007-10-05 | 2016-09-14 | Affymetrix, Inc. | Assays auf der Basis hoch gebündelter Partikel |
| US20090215050A1 (en) * | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
| US20090298709A1 (en) * | 2008-05-28 | 2009-12-03 | Affymetrix, Inc. | Assays for determining telomere length and repeated sequence copy number |
| JP2012506705A (ja) | 2008-10-27 | 2012-03-22 | キアジェン ゲイサーズバーグ インコーポレイテッド | 迅速に結果を得るハイブリッドキャプチャー法による分析およびシステム |
| CA2750338C (en) * | 2009-01-28 | 2019-06-25 | Qiagen Gaithersburg, Inc. | Sequence-specific large volume sample preparation method and assay |
| CN102414327B (zh) | 2009-05-01 | 2015-04-08 | 奇亚根盖瑟斯堡股份有限公司 | 用于在样品中检测rna剪接形式的非靶向扩增方法 |
| WO2011032124A1 (en) | 2009-09-14 | 2011-03-17 | Qiagen Gaithersburg, Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
| WO2011038403A1 (en) | 2009-09-28 | 2011-03-31 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
| JP2013517803A (ja) | 2010-01-29 | 2013-05-20 | キアジェン ゲイサーズバーグ インコーポレイテッド | サンプル中のhpvの存在を決定および確認する方法 |
| JP6103941B2 (ja) * | 2010-01-29 | 2017-03-29 | キアジェン ゲイサーズバーグ インコーポレイテッド | 核酸の配列特異的精製および多重分析のための方法および組成物 |
| CA2799200A1 (en) | 2010-05-19 | 2011-11-24 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| EP3034625B1 (de) | 2010-10-21 | 2017-10-04 | Advanced Cell Diagnostics, Inc. | Hochsensitives verfahren für den in-situ-nachweis von nukleinsäuren |
| WO2012116220A2 (en) | 2011-02-24 | 2012-08-30 | Qiagen Gaithersburg, Inc. | Materials and methods for detection of hpv nucleic acid |
| AT512416B1 (de) | 2012-02-13 | 2013-10-15 | Greiner Bio One Gmbh | Anordnung und verfahren zum nachweis von mikroorganismen in einem kulturgefäss |
| US9783841B2 (en) | 2012-10-04 | 2017-10-10 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of target nucleic acids in a cellular sample |
| US9273349B2 (en) | 2013-03-14 | 2016-03-01 | Affymetrix, Inc. | Detection of nucleic acids |
| JP6734011B2 (ja) * | 2014-06-06 | 2020-08-05 | 古河電気工業株式会社 | 生体分子検出用試験キット、及びこれを用いた生体分子の検出方法、並びにこれらに用いられる生体分子検出用試験片及び生体分子検出用標識試薬 |
| CN104569383A (zh) * | 2015-01-13 | 2015-04-29 | 科蒂亚(新乡)生物技术有限公司 | 一种在聚乙烯微孔板上包被核酸的方法 |
| EP3362462B1 (de) | 2015-10-12 | 2021-07-21 | Advanced Cell Diagnostics, Inc. | In-situ-detektion von nukleotidvarianten bei proben mit hohem rauschen sowie zugehörige zusammensetzungen und verfahren |
| USD825184S1 (en) | 2017-02-22 | 2018-08-14 | Yeti Coolers, Llc | Bag |
| US11076666B2 (en) | 2017-03-08 | 2021-08-03 | Yeti Coolers, Llc | Container with magnetic closure |
| US10954055B2 (en) | 2017-03-08 | 2021-03-23 | Yeti Coolers, Llc | Container with magnetic closure |
| CA3054439A1 (en) | 2017-03-08 | 2018-09-13 | Yeti Coolers, Llc | Container with magnetic closure |
| USD909063S1 (en) | 2019-03-08 | 2021-02-02 | Yeti Coolers, Llc | Bag |
| WO2022076500A1 (en) | 2020-10-08 | 2022-04-14 | Ecolab Usa Inc. | System and technique for detecting cleaning chemical usage to control cleaning efficacy |
| US11992104B2 (en) | 2022-02-16 | 2024-05-28 | Yeti Coolers, Llc | Container with resealable closure |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3379659D1 (en) * | 1983-07-29 | 1989-05-24 | Henning Berlin Gmbh | Preactivated surfaces of synthetic materials for immobilizing organochemical and biological substances, process for preparing them and their use |
| US4748111A (en) * | 1984-03-12 | 1988-05-31 | Molecular Diagnostics, Inc. | Nucleic acid-protein conjugate used in immunoassay |
| US4657853A (en) * | 1984-09-14 | 1987-04-14 | E. I. Du Pont De Nemours And Company | Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody |
| DE3524451A1 (de) * | 1985-07-09 | 1987-03-12 | Behringwerke Ag | Mit ueberzuegen versehene formkoerper zur bindung von bioaffinen substanzen, verfahren zu ihrer herstellung sowie ihre verwendung |
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| CA1339351C (en) * | 1987-10-15 | 1997-08-26 | Michael S. Urdea | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| CA2031659A1 (en) * | 1990-01-26 | 1991-07-27 | John B. Findlay | Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods |
| DE69032425T2 (de) * | 1990-05-11 | 1998-11-26 | Microprobe Corp., Bothell, Wash. | Teststreifen zum Eintauchen für Nukleinsäure-Hybridisierungsassays und Verfahren zur kovalenten Immobilisierung von Oligonucleotiden |
-
1991
- 1991-12-23 US US07/813,338 patent/US5747244A/en not_active Expired - Lifetime
-
1992
- 1992-12-22 CA CA002125145A patent/CA2125145A1/en not_active Abandoned
- 1992-12-22 AT AT93902855T patent/ATE191237T1/de not_active IP Right Cessation
- 1992-12-22 DE DE69230864T patent/DE69230864T2/de not_active Expired - Lifetime
- 1992-12-22 JP JP51195693A patent/JP3515781B2/ja not_active Expired - Fee Related
- 1992-12-22 WO PCT/US1992/011343 patent/WO1993013224A1/en not_active Ceased
- 1992-12-22 EP EP93902855A patent/EP0620864B1/de not_active Expired - Lifetime
- 1992-12-22 AU AU34276/93A patent/AU3427693A/en not_active Abandoned
-
1995
- 1995-05-10 US US08/438,639 patent/US5712383A/en not_active Expired - Lifetime
-
2003
- 2003-05-28 JP JP2003151687A patent/JP2004004087A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2125145A1 (en) | 1993-07-08 |
| US5712383A (en) | 1998-01-27 |
| DE69230864T2 (de) | 2000-11-09 |
| JP3515781B2 (ja) | 2004-04-05 |
| WO1993013224A1 (en) | 1993-07-08 |
| AU3427693A (en) | 1993-07-28 |
| US5747244A (en) | 1998-05-05 |
| JP2004004087A (ja) | 2004-01-08 |
| EP0620864B1 (de) | 2000-03-29 |
| JPH07502656A (ja) | 1995-03-23 |
| EP0620864A1 (de) | 1994-10-26 |
| DE69230864D1 (de) | 2000-05-04 |
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