ATE187460T1 - Kovalentgebundene dimere von glycopeptid- antibiotika - Google Patents

Kovalentgebundene dimere von glycopeptid- antibiotika

Info

Publication number
ATE187460T1
ATE187460T1 AT97302417T AT97302417T ATE187460T1 AT E187460 T1 ATE187460 T1 AT E187460T1 AT 97302417 T AT97302417 T AT 97302417T AT 97302417 T AT97302417 T AT 97302417T AT E187460 T1 ATE187460 T1 AT E187460T1
Authority
AT
Austria
Prior art keywords
covalene
glycopeptide antibiotics
glycopeptide
bonded dimers
dimers
Prior art date
Application number
AT97302417T
Other languages
English (en)
Inventor
Douglas Richard Stack
Richard Craig Thompson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE187460T1 publication Critical patent/ATE187460T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97302417T 1996-04-12 1997-04-08 Kovalentgebundene dimere von glycopeptid- antibiotika ATE187460T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1530096P 1996-04-12 1996-04-12
US3173596P 1996-11-25 1996-11-25

Publications (1)

Publication Number Publication Date
ATE187460T1 true ATE187460T1 (de) 1999-12-15

Family

ID=26687203

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97302417T ATE187460T1 (de) 1996-04-12 1997-04-08 Kovalentgebundene dimere von glycopeptid- antibiotika

Country Status (11)

Country Link
EP (1) EP0802199B1 (de)
JP (1) JP4159110B2 (de)
AT (1) ATE187460T1 (de)
AU (1) AU2609297A (de)
CA (1) CA2251086C (de)
DE (2) DE69700894T4 (de)
DK (1) DK0802199T3 (de)
ES (1) ES2140184T3 (de)
GR (1) GR3032834T3 (de)
PT (1) PT802199E (de)
WO (1) WO1997038706A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
AU3307399A (en) * 1998-02-20 1999-09-06 Advanced Medicine, Inc. Novel antibacterial agents
AU4549999A (en) * 1998-06-08 1999-12-30 Advanced Medicine, Inc. Novel polyene macrolide compounds and uses
EP1085846A2 (de) * 1998-06-08 2001-03-28 Advanced Medicine, Inc. Mehrfachbindende inhibitoren des microsomalen triglyceridtransferase-proteins
US6710168B1 (en) 1999-05-19 2004-03-23 The Trustees Of The University Of Princeton Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
JP2002520422A (ja) 1998-07-14 2002-07-09 プリンストン ユニバーシティ グリコペプチド抗生物質、グリコペプチド抗生物質のコンビナトリアルライブラリーおよびその作成方法
CZ301184B6 (cs) 1998-12-23 2009-12-02 Theravance, Inc. Glykopeptidový derivát a farmaceutické prostredky, které jej obsahují
WO2000069893A1 (en) * 1999-05-19 2000-11-23 Merck & Co., Inc. Glycopeptide antibacterial compounds, compositions containing same and methods of using same
KR20070092719A (ko) 2004-11-29 2007-09-13 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 글리코펩타이드 항생 물질 모노머 유도체
JP5192384B2 (ja) 2005-09-22 2013-05-08 メディバス エルエルシー ビス−（α−アミノ）−ジオール−ジエステル含有ポリ（エステルアミド）およびポリ（エステルウレタン）組成物および使用の方法
CA2623239C (en) 2005-09-22 2016-07-12 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
CN101397333A (zh) * 2007-09-27 2009-04-01 浙江医药股份有限公司新昌制药厂 去羟基万古霉素及其制备方法、和其药物组合物及其用途
KR20100109934A (ko) 2007-12-26 2010-10-11 시오노기세야쿠 가부시키가이샤 글리코펩티드 항생 물질 배당화 유도체
CN102083862A (zh) 2008-04-01 2011-06-01 康奈尔大学 有机-可溶性壳聚糖盐和由其制备的壳聚糖衍生生物材料
US20140171357A1 (en) * 2011-03-24 2014-06-19 Seachaid Pharmaceuticals, Inc. Vancomycin derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521335A (en) * 1983-07-13 1985-06-04 Smithkline Beckman Corporation Aglycone and pseudo-aglycones of the AAD 216 antibiotics

Also Published As

Publication number Publication date
PT802199E (pt) 2000-04-28
DE69700894T2 (de) 2000-05-04
GR3032834T3 (en) 2000-07-31
WO1997038706A1 (en) 1997-10-23
JP4159110B2 (ja) 2008-10-01
EP0802199A3 (de) 1997-11-05
CA2251086C (en) 2007-02-20
DE69700894T4 (de) 2000-09-21
AU2609297A (en) 1997-11-07
JP2000509030A (ja) 2000-07-18
EP0802199A2 (de) 1997-10-22
DK0802199T3 (da) 2000-05-01
EP0802199B1 (de) 1999-12-08
CA2251086A1 (en) 1997-10-23
DE69700894D1 (de) 2000-01-13
ES2140184T3 (es) 2000-02-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee