DE69700894D1 - Kovalentgebundene Dimere von Glycopeptid-Antibiotika - Google Patents

Kovalentgebundene Dimere von Glycopeptid-Antibiotika

Info

Publication number
DE69700894D1
DE69700894D1 DE69700894A DE69700894A DE69700894D1 DE 69700894 D1 DE69700894 D1 DE 69700894D1 DE 69700894 A DE69700894 A DE 69700894A DE 69700894 A DE69700894 A DE 69700894A DE 69700894 D1 DE69700894 D1 DE 69700894D1
Authority
DE
Germany
Prior art keywords
covalently bound
glycopeptide antibiotics
glycopeptide
dimers
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69700894A
Other languages
English (en)
Other versions
DE69700894T4 (de
DE69700894T2 (de
Inventor
Douglas Richard Stack
Richard Craig Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69700894D1 publication Critical patent/DE69700894D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69700894A 1996-04-12 1997-04-08 Kovalentgebundene Dimere von Glycopeptid-Antibiotika Expired - Fee Related DE69700894D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1530096P 1996-04-12 1996-04-12
US3173596P 1996-11-25 1996-11-25

Publications (1)

Publication Number Publication Date
DE69700894D1 true DE69700894D1 (de) 2000-01-13

Family

ID=26687203

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69700894A Expired - Fee Related DE69700894D1 (de) 1996-04-12 1997-04-08 Kovalentgebundene Dimere von Glycopeptid-Antibiotika
DE69700894T Expired - Lifetime DE69700894T4 (de) 1996-04-12 1997-04-08 Kovalentgebundene Dimere von Glycopeptid-Antibiotika

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69700894T Expired - Lifetime DE69700894T4 (de) 1996-04-12 1997-04-08 Kovalentgebundene Dimere von Glycopeptid-Antibiotika

Country Status (11)

Country Link
EP (1) EP0802199B1 (de)
JP (1) JP4159110B2 (de)
AT (1) ATE187460T1 (de)
AU (1) AU2609297A (de)
CA (1) CA2251086C (de)
DE (2) DE69700894D1 (de)
DK (1) DK0802199T3 (de)
ES (1) ES2140184T3 (de)
GR (1) GR3032834T3 (de)
PT (1) PT802199E (de)
WO (1) WO1997038706A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
IT1307018B1 (it) * 1998-02-20 2001-10-23 Advanced Medicine Inc Agenti antibatterici.
WO1999064040A1 (en) * 1998-06-08 1999-12-16 Advanced Medicine, Inc. Novel polyene macrolide compounds and uses
AU4543899A (en) * 1998-06-08 1999-12-30 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
JP2002520422A (ja) 1998-07-14 2002-07-09 プリンストン ユニバーシティ グリコペプチド抗生物質、グリコペプチド抗生物質のコンビナトリアルライブラリーおよびその作成方法
US6710168B1 (en) 1999-05-19 2004-03-23 The Trustees Of The University Of Princeton Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
CN1249081C (zh) 1998-12-23 2006-04-05 施万制药 糖肽衍生物或含有它们的药物组合物
WO2000069893A1 (en) * 1999-05-19 2000-11-23 Merck & Co., Inc. Glycopeptide antibacterial compounds, compositions containing same and methods of using same
KR20070092719A (ko) 2004-11-29 2007-09-13 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 글리코펩타이드 항생 물질 모노머 유도체
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
EP1926780B1 (de) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-haltige poly(esteramid) und poly(esterurethan)-zusammensetzungen und verwendungsverfahren
CN101397333A (zh) * 2007-09-27 2009-04-01 浙江医药股份有限公司新昌制药厂 去羟基万古霉素及其制备方法、和其药物组合物及其用途
WO2009081958A1 (ja) 2007-12-26 2009-07-02 Shionogi & Co., Ltd. グリコペプチド抗生物質配糖化誘導体
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
EP2688580A4 (de) * 2011-03-24 2015-03-25 Seachaid Pharmaceuticals Inc Vancomycinderivate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521335A (en) * 1983-07-13 1985-06-04 Smithkline Beckman Corporation Aglycone and pseudo-aglycones of the AAD 216 antibiotics

Also Published As

Publication number Publication date
EP0802199B1 (de) 1999-12-08
JP2000509030A (ja) 2000-07-18
ATE187460T1 (de) 1999-12-15
DE69700894T4 (de) 2000-09-21
JP4159110B2 (ja) 2008-10-01
GR3032834T3 (en) 2000-07-31
ES2140184T3 (es) 2000-02-16
EP0802199A3 (de) 1997-11-05
DK0802199T3 (da) 2000-05-01
CA2251086A1 (en) 1997-10-23
AU2609297A (en) 1997-11-07
CA2251086C (en) 2007-02-20
PT802199E (pt) 2000-04-28
WO1997038706A1 (en) 1997-10-23
DE69700894T2 (de) 2000-05-04
EP0802199A2 (de) 1997-10-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8339 Ceased/non-payment of the annual fee