ATE181918T1 - Purinderivate und ihre pharmazeutisch akzeptablen salze - Google Patents
Purinderivate und ihre pharmazeutisch akzeptablen salzeInfo
- Publication number
- ATE181918T1 ATE181918T1 AT95104408T AT95104408T ATE181918T1 AT E181918 T1 ATE181918 T1 AT E181918T1 AT 95104408 T AT95104408 T AT 95104408T AT 95104408 T AT95104408 T AT 95104408T AT E181918 T1 ATE181918 T1 AT E181918T1
- Authority
- AT
- Austria
- Prior art keywords
- present
- purine derivatives
- compounds
- pharmaceutically acceptable
- acceptable salts
- Prior art date
Links
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000003212 purines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 210000003097 mucus Anatomy 0.000 abstract 2
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical class 0.000 abstract 2
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 abstract 2
- 230000028327 secretion Effects 0.000 abstract 2
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 230000001133 acceleration Effects 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 230000011514 reflex Effects 0.000 abstract 1
- 206010039083 rhinitis Diseases 0.000 abstract 1
- 206010041232 sneezing Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP07933694A JP3497554B2 (ja) | 1994-03-25 | 1994-03-25 | 新規プリン誘導体及びその薬学的に許容される塩 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE181918T1 true ATE181918T1 (de) | 1999-07-15 |
Family
ID=13687063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95104408T ATE181918T1 (de) | 1994-03-25 | 1995-03-24 | Purinderivate und ihre pharmazeutisch akzeptablen salze |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5658918A (enExample) |
| EP (1) | EP0673938B1 (enExample) |
| JP (1) | JP3497554B2 (enExample) |
| KR (1) | KR100355096B1 (enExample) |
| CN (1) | CN1045443C (enExample) |
| AT (1) | ATE181918T1 (enExample) |
| AU (1) | AU683981B2 (enExample) |
| CA (1) | CA2145432A1 (enExample) |
| DE (1) | DE69510582T2 (enExample) |
| TW (1) | TW416957B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9721189D0 (en) | 1997-10-08 | 1997-12-03 | Speywood Lab The Limited | Analgesic conjugates |
| GB9818548D0 (en) | 1998-08-25 | 1998-10-21 | Microbiological Res Authority | Treatment of mucas hypersecretion |
| US8790897B2 (en) | 1998-08-25 | 2014-07-29 | Syntaxin Ltd. | Treatment of mucus hypersecretion |
| US20040071736A1 (en) | 1998-08-25 | 2004-04-15 | Health Protection Agency | Methods and compounds for the treatment of mucus hypersecretion |
| US20090023723A1 (en) * | 2005-09-21 | 2009-01-22 | Pharmacopeia Drug Discovery, Inc. | Purinone derivatives for treating neurodegenerative diseases |
| BRPI0808746B8 (pt) * | 2007-03-28 | 2021-05-25 | Neurosearch As | derivado de purinila como modulador do canal de potássio, composição farmacêutica, e, uso de um derivado de purinila. |
| JP2014076947A (ja) * | 2011-02-03 | 2014-05-01 | Dainippon Sumitomo Pharma Co Ltd | ２−オキシ置換８−オキソジヒドロプリン誘導体 |
| JP6932394B2 (ja) | 2016-11-11 | 2021-09-08 | ヘポ ファーマスーティカル カンパニー リミテッド | 含窒素複素環化合物、製造方法、中間体、医薬組成物及び応用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52120135A (en) * | 1976-03-30 | 1977-10-08 | Nippon Zoki Pharmaceutical Co | Alllnerve tranquilling agent |
| JPS6058726B2 (ja) * | 1977-10-05 | 1985-12-21 | 日本臓器製薬株式会社 | プリン誘導体を有効成分として含有する抗アレルギ−，鎮痛，鎮静剤 |
| JPH01299229A (ja) * | 1988-05-25 | 1989-12-04 | Rohto Pharmaceut Co Ltd | 肥満症治療剤 |
| FR2659656B1 (fr) * | 1990-03-15 | 1994-09-09 | Sanofi Sa | Derives de pyrimidinedione-2,4 et medicaments les contenant. |
| JP6126527B2 (ja) | 2013-12-27 | 2017-05-10 | 日本電信電話株式会社 | 誘電体デバイス |
| JP6058726B2 (ja) | 2015-03-30 | 2017-01-11 | 積水メディカル株式会社 | 血液凝固反応における血液凝固時間延長剤 |
-
1994
- 1994-03-25 JP JP07933694A patent/JP3497554B2/ja not_active Expired - Fee Related
-
1995
- 1995-02-25 TW TW084101761A patent/TW416957B/zh not_active IP Right Cessation
- 1995-03-21 KR KR1019950005990A patent/KR100355096B1/ko not_active Expired - Fee Related
- 1995-03-23 US US08/409,054 patent/US5658918A/en not_active Expired - Fee Related
- 1995-03-24 CN CN95103575A patent/CN1045443C/zh not_active Expired - Fee Related
- 1995-03-24 CA CA002145432A patent/CA2145432A1/en not_active Abandoned
- 1995-03-24 DE DE69510582T patent/DE69510582T2/de not_active Expired - Fee Related
- 1995-03-24 AT AT95104408T patent/ATE181918T1/de not_active IP Right Cessation
- 1995-03-24 EP EP95104408A patent/EP0673938B1/en not_active Expired - Lifetime
- 1995-03-27 AU AU15089/95A patent/AU683981B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69510582T2 (de) | 1999-11-25 |
| KR100355096B1 (ko) | 2002-12-26 |
| JPH07258257A (ja) | 1995-10-09 |
| EP0673938B1 (en) | 1999-07-07 |
| AU1508995A (en) | 1995-10-05 |
| CA2145432A1 (en) | 1995-09-26 |
| EP0673938A3 (enExample) | 1995-11-08 |
| DE69510582D1 (de) | 1999-08-12 |
| KR950032194A (ko) | 1995-12-20 |
| CN1114318A (zh) | 1996-01-03 |
| JP3497554B2 (ja) | 2004-02-16 |
| US5658918A (en) | 1997-08-19 |
| CN1045443C (zh) | 1999-10-06 |
| TW416957B (en) | 2001-01-01 |
| AU683981B2 (en) | 1997-11-27 |
| EP0673938A2 (en) | 1995-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |