ATE179426T1 - Anthracyclin-derivate, die ein trifluormethylierte zuckereinheiten enthalten - Google Patents

Anthracyclin-derivate, die ein trifluormethylierte zuckereinheiten enthalten

Info

Publication number
ATE179426T1
ATE179426T1 AT95910796T AT95910796T ATE179426T1 AT E179426 T1 ATE179426 T1 AT E179426T1 AT 95910796 T AT95910796 T AT 95910796T AT 95910796 T AT95910796 T AT 95910796T AT E179426 T1 ATE179426 T1 AT E179426T1
Authority
AT
Austria
Prior art keywords
anthracycline derivatives
anticancer
formula
trifluoromethylated
daunomycin
Prior art date
Application number
AT95910796T
Other languages
English (en)
Inventor
Tomio New Fuji Mansio Takeuchi
Sumio Umezawa
Tsutomu Tsuchiya
Yasushi Takagi
Original Assignee
Zaidan Hojin Biseibutsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zaidan Hojin Biseibutsu filed Critical Zaidan Hojin Biseibutsu
Application granted granted Critical
Publication of ATE179426T1 publication Critical patent/ATE179426T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/34—Halogenated alcohols
    • C07C31/42—Polyhydroxylic acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1786—Unsaturated ethers containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT95910796T 1994-03-11 1995-03-10 Anthracyclin-derivate, die ein trifluormethylierte zuckereinheiten enthalten ATE179426T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6771494 1994-03-11

Publications (1)

Publication Number Publication Date
ATE179426T1 true ATE179426T1 (de) 1999-05-15

Family

ID=13352911

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910796T ATE179426T1 (de) 1994-03-11 1995-03-10 Anthracyclin-derivate, die ein trifluormethylierte zuckereinheiten enthalten

Country Status (7)

Country Link
US (2) US5719130A (de)
EP (1) EP0749976B1 (de)
AT (1) ATE179426T1 (de)
CA (1) CA2185247A1 (de)
DE (1) DE69509377T2 (de)
ES (1) ES2131819T3 (de)
WO (1) WO1995024412A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0912590A (ja) * 1995-06-23 1997-01-14 Microbial Chem Res Found ４−アミノ−２，４，６−トリデオキシ−２−フルオロ−マンノピラノシル基を有する新規アンスラサイクリン誘導体
JPH10175992A (ja) * 1996-12-16 1998-06-30 Microbial Chem Res Found ４−アミノ−２，４，６−トリデオキシ−２−フルオロ−α−Ｌ−タロピラノシル基を有する新規アンスラサイクリン誘導体
US6197809B1 (en) * 1998-12-23 2001-03-06 Ardenia Investments Ltd. Compounds for the treatment of cancer
US20040254099A1 (en) * 1999-04-21 2004-12-16 Adherex Technologies, Inc. Compounds and methods for modulating beta-catenin mediated gene expression
US6303576B1 (en) * 1999-04-21 2001-10-16 Adherex Technologies Inc. Compounds and methods for modulating β-catenin mediated gene expression
US20040038904A1 (en) * 2002-05-21 2004-02-26 Angela Ogden Method of treating multiple sclerosis
EP2825206A1 (de) 2012-03-16 2015-01-21 The Johns Hopkins University Formulierungen mit kontrollierter freisetzung zur verabreichung von hif-1-hemmern

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0631298B2 (ja) * 1985-12-18 1994-04-27 財団法人微生物化学研究会 新規アンスラサイクリン誘導体，抗腫瘍剤，及び製造法
JPH0742304B2 (ja) * 1986-12-05 1995-05-10 財団法人微生物化学研究会 新規なアンスラサイクリン誘導体およびその製造法
JPH06797B2 (ja) * 1987-01-30 1994-01-05 財団法人相模中央化学研究所 １４−フルオロダウノルビシン誘導体
KR100211417B1 (ko) * 1990-11-30 1999-10-01 유충식 L-탈로피라노시드 유도체 및 그의 제조방법

Also Published As

Publication number Publication date
US5719130A (en) 1998-02-17
EP0749976B1 (de) 1999-04-28
DE69509377D1 (de) 1999-06-02
US5801257A (en) 1998-09-01
EP0749976A4 (de) 1997-03-19
EP0749976A1 (de) 1996-12-27
ES2131819T3 (es) 1999-08-01
CA2185247A1 (en) 1995-09-14
DE69509377T2 (de) 1999-11-18
WO1995024412A1 (fr) 1995-09-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee