ATE17940T1 - Verfahren zur extemporierten herstellung einer mit radioaktivem jod markierten injizierbaren fettsaeure und herstellung von in der ausfuehrung dieses verfahrens brauchbaren jodierten derivaten. - Google Patents
Verfahren zur extemporierten herstellung einer mit radioaktivem jod markierten injizierbaren fettsaeure und herstellung von in der ausfuehrung dieses verfahrens brauchbaren jodierten derivaten.Info
- Publication number
- ATE17940T1 ATE17940T1 AT82401192T AT82401192T ATE17940T1 AT E17940 T1 ATE17940 T1 AT E17940T1 AT 82401192 T AT82401192 T AT 82401192T AT 82401192 T AT82401192 T AT 82401192T AT E17940 T1 ATE17940 T1 AT E17940T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- fatty acid
- radioactive iodine
- performance
- derivatives useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/04—Acyclic alcohols with carbon-to-carbon triple bonds
- C07C33/042—Acyclic alcohols with carbon-to-carbon triple bonds with only one triple bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/18—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon triple bonds as unsaturation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8113039A FR2508902B1 (fr) | 1981-07-02 | 1981-07-02 | Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede |
| EP82401192A EP0069648B1 (de) | 1981-07-02 | 1982-06-28 | Verfahren zur extemporierten Herstellung einer mit radioaktivem Jod markierten injizierbaren Fettsäure und Herstellung von in der Ausführung dieses Verfahrens brauchbaren jodierten Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE17940T1 true ATE17940T1 (de) | 1986-02-15 |
Family
ID=9260121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82401192T ATE17940T1 (de) | 1981-07-02 | 1982-06-28 | Verfahren zur extemporierten herstellung einer mit radioaktivem jod markierten injizierbaren fettsaeure und herstellung von in der ausfuehrung dieses verfahrens brauchbaren jodierten derivaten. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4476106A (de) |
| EP (1) | EP0069648B1 (de) |
| JP (1) | JPS5859926A (de) |
| AT (1) | ATE17940T1 (de) |
| CA (1) | CA1198737A (de) |
| DK (1) | DK293082A (de) |
| ES (1) | ES8304912A1 (de) |
| FR (1) | FR2508902B1 (de) |
| NO (1) | NO162612C (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010010666A1 (de) * | 2010-03-01 | 2011-09-01 | Sven Reske | Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2947500C2 (de) * | 1979-11-24 | 1984-05-10 | Dutschka, Klaus, 4300 Essen | Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber |
| US4649039A (en) * | 1984-07-03 | 1987-03-10 | E. I. Du Pont De Nemours And Company | Radiolabeling of methionine-containing proteins and peptides |
| US4764358A (en) * | 1985-04-30 | 1988-08-16 | The United States Of America As Represented By The United States Department Of Energy | Radiolabeled dimethyl branched long chain fatty acid for heart imaging |
| JP2715240B2 (ja) * | 1993-05-18 | 1998-02-18 | 株式会社第一ラジオアイソトープ研究所 | 放射性ヨウ素標識脂肪酸−シクロデキストリン複合体およびこれを含有するイメージング剤 |
| FR2726765B1 (fr) * | 1994-11-14 | 1996-12-20 | Cis Bio Int | Compositions radiopharmaceutiques comprenant un complexe d'inclusion d'une cyclodextrine et d'un acide gras radiohalogene |
| DE69636881T2 (de) * | 1995-12-01 | 2007-09-20 | Molecular Insight Pharmaceuticals, Inc., Cambridge | Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung |
| EP1384706A1 (de) * | 2002-07-24 | 2004-01-28 | Degussa AG | Verfahren zur Monoalkylierung C-H-acider Methylengruppen |
| CN113087623A (zh) * | 2021-04-13 | 2021-07-09 | 苏州昊帆生物股份有限公司 | 一种8-溴辛酸乙酯的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2810696C3 (de) * | 1978-03-11 | 1982-02-25 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verfahren zur Gewinnung von ω-↑123↑J-Hexadecansäure oder ω↑123↑J-Heptadecansäure und deren Verwendung als Radiopharmaka |
| DE2828623C2 (de) * | 1978-06-29 | 1983-11-17 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung |
| DE2914089C2 (de) * | 1979-04-07 | 1982-02-11 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verfahren zur Herstellung von ω-↑123↑J-markierten Fettsäuren |
| DE2947500C2 (de) * | 1979-11-24 | 1984-05-10 | Dutschka, Klaus, 4300 Essen | Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber |
| DE3127239A1 (de) * | 1981-07-10 | 1983-01-20 | Hoechst Ag, 6000 Frankfurt | Quartaere n-alkyl-n,n',n'-polyoxyalkyl-(alpha),(omega)-diaminoalkylenfettsaeureester, verfahren zu deren herstellung und deren verwendung |
-
1981
- 1981-07-02 FR FR8113039A patent/FR2508902B1/fr not_active Expired
-
1982
- 1982-06-25 NO NO822147A patent/NO162612C/no unknown
- 1982-06-28 US US06/392,581 patent/US4476106A/en not_active Expired - Lifetime
- 1982-06-28 EP EP82401192A patent/EP0069648B1/de not_active Expired
- 1982-06-28 AT AT82401192T patent/ATE17940T1/de not_active IP Right Cessation
- 1982-06-30 DK DK293082A patent/DK293082A/da unknown
- 1982-07-01 ES ES513640A patent/ES8304912A1/es not_active Expired
- 1982-07-02 CA CA000406493A patent/CA1198737A/en not_active Expired
- 1982-07-02 JP JP57115319A patent/JPS5859926A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010010666A1 (de) * | 2010-03-01 | 2011-09-01 | Sven Reske | Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren |
Also Published As
| Publication number | Publication date |
|---|---|
| ES513640A0 (es) | 1983-03-16 |
| JPH0365333B2 (de) | 1991-10-11 |
| NO822147L (no) | 1983-01-03 |
| EP0069648A1 (de) | 1983-01-12 |
| JPS5859926A (ja) | 1983-04-09 |
| FR2508902A1 (fr) | 1983-01-07 |
| CA1198737A (en) | 1985-12-31 |
| ES8304912A1 (es) | 1983-03-16 |
| US4476106A (en) | 1984-10-09 |
| DK293082A (da) | 1983-01-03 |
| NO162612B (no) | 1989-10-16 |
| NO162612C (no) | 1990-01-24 |
| FR2508902B1 (fr) | 1985-09-06 |
| EP0069648B1 (de) | 1986-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |