ATE176931T1 - Verfahren zur enzymatischen herstellung von optisch aktiven estern einer transglycidsäure - Google Patents
Verfahren zur enzymatischen herstellung von optisch aktiven estern einer transglycidsäureInfo
- Publication number
- ATE176931T1 ATE176931T1 AT93203495T AT93203495T ATE176931T1 AT E176931 T1 ATE176931 T1 AT E176931T1 AT 93203495 T AT93203495 T AT 93203495T AT 93203495 T AT93203495 T AT 93203495T AT E176931 T1 ATE176931 T1 AT E176931T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- acid
- ester
- transglycid
- trans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9202208A NL9202208A (nl) | 1992-12-18 | 1992-12-18 | Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE176931T1 true ATE176931T1 (de) | 1999-03-15 |
Family
ID=19861657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93203495T ATE176931T1 (de) | 1992-12-18 | 1993-12-13 | Verfahren zur enzymatischen herstellung von optisch aktiven estern einer transglycidsäure |
Country Status (11)
Country | Link |
---|---|
US (1) | US5407828A (de) |
EP (1) | EP0602740B1 (de) |
JP (1) | JP3781788B2 (de) |
AT (1) | ATE176931T1 (de) |
CA (1) | CA2111595C (de) |
DE (1) | DE69323600T2 (de) |
DK (1) | DK0602740T3 (de) |
ES (1) | ES2129491T3 (de) |
FI (1) | FI102974B (de) |
IL (1) | IL108029A (de) |
NL (1) | NL9202208A (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1249777B (it) * | 1990-05-17 | 1995-03-18 | Zambon Spa | Processo per la preparazione di intermedi per la sintesi del diltiazem |
JP3610600B2 (ja) * | 1994-08-22 | 2005-01-12 | チッソ株式会社 | 光学活性エンド−2−ノルボルネオール類の製造方法 |
WO1999041405A1 (en) | 1998-02-17 | 1999-08-19 | G.D. Searle & Co. | Process for the enzymatic resolution of lactams |
IT1302261B1 (it) | 1998-09-24 | 2000-09-05 | Zambon Spa | Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli |
CA2574625A1 (en) * | 2004-07-23 | 2006-01-26 | Thijs Kuilman | Process for the preparation of (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionamide and (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionic acid alkyl ester |
CN107446960A (zh) * | 2017-09-30 | 2017-12-08 | 湖南理工学院 | 一种采用生物酶催化立体选择性拆分2,3‑二苯基丙酸对映体的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2628667B2 (ja) * | 1986-10-17 | 1997-07-09 | ノボ ノルディスク アクティーゼルスカブ | 位置非特異性リパーゼ |
US5273898A (en) * | 1986-10-17 | 1993-12-28 | Noro Nordisk A/S | Thermally stable and positionally non-specific lipase isolated from Candida |
DE3886412T2 (de) * | 1987-09-28 | 1994-05-11 | Novonordisk As | Verfahren zur immobilisierung von lipasen. |
NL8801311A (nl) * | 1988-05-20 | 1989-12-18 | Stamicarbon | Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem. |
FI95931C (fi) * | 1988-09-02 | 1996-04-10 | Tanabe Seiyaku Co | Menetelmä (2R,3S)-3-(4-metoksifenyyli)glysidiinihapon alemman alkyyliesterin valmistamiseksi |
US6521445B1 (en) * | 1988-10-26 | 2003-02-18 | Sepracor, Inc. | Process for preparing optically active glycidate esters |
JPH088879B2 (ja) * | 1989-09-13 | 1996-01-31 | 田辺製薬株式会社 | 光学活性3―フェニルグリシッド酸エステル類化合物の製法 |
FR2672600B1 (fr) * | 1991-02-08 | 1994-10-14 | Synthelabo | Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle. |
-
1992
- 1992-12-18 NL NL9202208A patent/NL9202208A/nl not_active Application Discontinuation
-
1993
- 1993-12-13 ES ES93203495T patent/ES2129491T3/es not_active Expired - Lifetime
- 1993-12-13 AT AT93203495T patent/ATE176931T1/de active
- 1993-12-13 DK DK93203495T patent/DK0602740T3/da active
- 1993-12-13 EP EP93203495A patent/EP0602740B1/de not_active Expired - Lifetime
- 1993-12-13 US US08/165,344 patent/US5407828A/en not_active Expired - Lifetime
- 1993-12-13 DE DE69323600T patent/DE69323600T2/de not_active Expired - Lifetime
- 1993-12-15 IL IL10802993A patent/IL108029A/en not_active IP Right Cessation
- 1993-12-16 JP JP31669193A patent/JP3781788B2/ja not_active Expired - Fee Related
- 1993-12-16 CA CA002111595A patent/CA2111595C/en not_active Expired - Fee Related
- 1993-12-17 FI FI935712A patent/FI102974B/fi active
Also Published As
Publication number | Publication date |
---|---|
CA2111595A1 (en) | 1994-06-19 |
JPH06335399A (ja) | 1994-12-06 |
DK0602740T3 (da) | 1999-09-27 |
EP0602740B1 (de) | 1999-02-24 |
IL108029A (en) | 1998-09-24 |
FI102974B1 (fi) | 1999-03-31 |
NL9202208A (nl) | 1994-07-18 |
DE69323600T2 (de) | 1999-09-23 |
CA2111595C (en) | 2004-12-14 |
FI935712A0 (fi) | 1993-12-17 |
US5407828A (en) | 1995-04-18 |
IL108029A0 (en) | 1994-04-12 |
EP0602740A1 (de) | 1994-06-22 |
FI935712A (fi) | 1994-06-19 |
DE69323600D1 (de) | 1999-04-01 |
ES2129491T3 (es) | 1999-06-16 |
FI102974B (fi) | 1999-03-31 |
JP3781788B2 (ja) | 2006-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |