ATE175954T1 - Verfahren zum herstellen von lignin-analoga und ausgangsprodukte dafür - Google Patents
Verfahren zum herstellen von lignin-analoga und ausgangsprodukte dafürInfo
- Publication number
- ATE175954T1 ATE175954T1 AT95117572T AT95117572T ATE175954T1 AT E175954 T1 ATE175954 T1 AT E175954T1 AT 95117572 T AT95117572 T AT 95117572T AT 95117572 T AT95117572 T AT 95117572T AT E175954 T1 ATE175954 T1 AT E175954T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- chem
- formula
- ring
- substituted
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229920005610 lignin Polymers 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002243 cyclohexanonyl group Chemical group *C1(*)C(=O)C(*)(*)C(*)(*)C(*)(*)C1(*)* 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- -1 lactone compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/22—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one naphthalene or hydrogenated naphthalene ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Steroid Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29811991 | 1991-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE175954T1 true ATE175954T1 (de) | 1999-02-15 |
Family
ID=17855421
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95117572T ATE175954T1 (de) | 1991-10-17 | 1992-10-15 | Verfahren zum herstellen von lignin-analoga und ausgangsprodukte dafür |
| AT92921331T ATE139990T1 (de) | 1991-10-17 | 1992-10-15 | Lignan-analoge, ihre herstellung und hypolipidemische arzneimittel |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92921331T ATE139990T1 (de) | 1991-10-17 | 1992-10-15 | Lignan-analoge, ihre herstellung und hypolipidemische arzneimittel |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US5420333A (member.php) |
| EP (2) | EP0597107B1 (member.php) |
| JP (1) | JP2839805B2 (member.php) |
| KR (1) | KR100252428B1 (member.php) |
| AT (2) | ATE175954T1 (member.php) |
| DE (2) | DE69228262D1 (member.php) |
| DK (2) | DK0597107T3 (member.php) |
| ES (2) | ES2091488T3 (member.php) |
| GR (1) | GR3020461T3 (member.php) |
| HU (1) | HU211296A9 (member.php) |
| TW (1) | TW209215B (member.php) |
| WO (1) | WO1993008155A1 (member.php) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0646570B1 (en) * | 1993-04-16 | 1998-06-24 | Shionogi & Co., Ltd. | Process for producing lignan compound |
| FR2707980B1 (fr) * | 1993-07-20 | 1995-09-01 | Adir | Nouveaux cyclohept[b]indoles et cyclooct[b]indoles, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| JP3655311B2 (ja) * | 1994-06-22 | 2005-06-02 | 塩野義製薬株式会社 | フタリド化合物の製造方法 |
| ID18046A (id) * | 1996-08-20 | 1998-02-19 | Takeda Chemical Industries Ltd | Senyawa siklik campuran, pembuatan dan penngunaannya. |
| KR20010080428A (ko) * | 1998-11-12 | 2001-08-22 | 케네쓰 아이. 모크 | 글루코스 및 지질을 저하시키는 화합물 |
| KR100352269B1 (ko) * | 1999-10-08 | 2002-09-12 | 한국생명공학연구원 | 저밀도 지질 단백질에 대해 항산화 활성을 갖는 리그난계 화합물 |
| FR2800738B1 (fr) | 1999-11-04 | 2002-02-08 | Corning Sa | Naphtopyranes ayant un substituant perfluoroalkyle en position 5, preparation et compositions et matrices (co)polymeres les renfermant |
| US6770024B1 (en) | 2000-03-28 | 2004-08-03 | Stony Brook Surgical Innovations, Inc. | Implantable counterpulsation cardiac assist device |
| TWI241195B (en) * | 2000-04-10 | 2005-10-11 | Shionogi & Co | Preventive agent for bile acidic diarrhea |
| WO2002009757A1 (en) * | 2000-08-01 | 2002-02-07 | Shionogi & Co., Ltd. | Preventives or remedies for obesity or fatty liver |
| AU2003271115A1 (en) * | 2002-10-08 | 2004-05-04 | Shionogi And Co., Ltd. | Process for producing enone ester |
| US7152611B2 (en) * | 2002-12-30 | 2006-12-26 | International Tape Partners, Llc | Coated multifilament dental devices overcoated with imbedded particulate |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| EP2995317A1 (en) | 2010-05-26 | 2016-03-16 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
| EP2771003B1 (en) | 2011-10-28 | 2017-04-19 | Lumena Pharmaceuticals LLC | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
| KR102051031B1 (ko) | 2011-10-28 | 2019-12-02 | 루메나 파마수티컬즈, 인코포레이티드 | 고담혈증 및 담즙 정체성 간 질환 치료용 담즙산 재순환 억제제 |
| CA2907214A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
| MX2015013193A (es) | 2013-03-15 | 2016-04-15 | Lumena Pharmaceuticals Inc | Inhibidores del reciclaje de acidos biliares para el tratamiento de colangitis esclerosante primaria y enfermedad inflamatoria intestinal. |
| WO2020167981A1 (en) | 2019-02-12 | 2020-08-20 | Mirum Pharmaceuticals, Inc. | Methods for increasing growth in pediatric subjects having cholestatic liver disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4771072A (en) * | 1985-01-10 | 1988-09-13 | Tanabe Seiyaku Co., Ltd. | Alkoxynaphthalene derivatives |
| JPS6310746A (ja) * | 1986-07-01 | 1988-01-18 | Tanabe Seiyaku Co Ltd | ナフタレン誘導体 |
| JPH0372422A (ja) * | 1989-05-16 | 1991-03-27 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
-
1992
- 1992-10-15 AT AT95117572T patent/ATE175954T1/de not_active IP Right Cessation
- 1992-10-15 ES ES92921331T patent/ES2091488T3/es not_active Expired - Lifetime
- 1992-10-15 DE DE69228262T patent/DE69228262D1/de not_active Expired - Fee Related
- 1992-10-15 DE DE69211994T patent/DE69211994T2/de not_active Expired - Fee Related
- 1992-10-15 JP JP4277151A patent/JP2839805B2/ja not_active Expired - Fee Related
- 1992-10-15 US US08/078,205 patent/US5420333A/en not_active Expired - Lifetime
- 1992-10-15 EP EP92921331A patent/EP0597107B1/en not_active Expired - Lifetime
- 1992-10-15 DK DK92921331.2T patent/DK0597107T3/da active
- 1992-10-15 WO PCT/JP1992/001342 patent/WO1993008155A1/ja not_active Ceased
- 1992-10-15 DK DK95117572T patent/DK0701991T3/da active
- 1992-10-15 EP EP95117572A patent/EP0701991B1/en not_active Expired - Lifetime
- 1992-10-15 ES ES95117572T patent/ES2129733T3/es not_active Expired - Lifetime
- 1992-10-15 AT AT92921331T patent/ATE139990T1/de not_active IP Right Cessation
- 1992-10-15 KR KR1019930701814A patent/KR100252428B1/ko not_active Expired - Fee Related
- 1992-10-17 TW TW081108267A patent/TW209215B/zh active
-
1994
- 1994-09-07 US US08/301,996 patent/US5449814A/en not_active Expired - Lifetime
-
1995
- 1995-04-18 US US08/423,346 patent/US5731455A/en not_active Expired - Fee Related
- 1995-05-22 US US08/445,506 patent/US5502216A/en not_active Expired - Fee Related
- 1995-06-30 HU HU95P/P00635P patent/HU211296A9/hu unknown
-
1996
- 1996-07-04 GR GR960401618T patent/GR3020461T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR930703236A (ko) | 1993-11-29 |
| DK0597107T3 (da) | 1996-07-29 |
| JP2839805B2 (ja) | 1998-12-16 |
| DE69228262D1 (de) | 1999-03-04 |
| EP0597107B1 (en) | 1996-07-03 |
| DE69211994T2 (de) | 1997-02-20 |
| WO1993008155A1 (fr) | 1993-04-29 |
| US5420333A (en) | 1995-05-30 |
| ES2091488T3 (es) | 1996-11-01 |
| DE69211994D1 (de) | 1996-08-08 |
| DK0701991T3 (da) | 1999-09-13 |
| ATE139990T1 (de) | 1996-07-15 |
| EP0597107A4 (en) | 1994-02-03 |
| US5731455A (en) | 1998-03-24 |
| US5502216A (en) | 1996-03-26 |
| US5449814A (en) | 1995-09-12 |
| JPH05310634A (ja) | 1993-11-22 |
| HU211296A9 (en) | 1995-11-28 |
| EP0701991A1 (en) | 1996-03-20 |
| ES2129733T3 (es) | 1999-06-16 |
| EP0701991B1 (en) | 1999-01-20 |
| GR3020461T3 (en) | 1996-10-31 |
| EP0597107A1 (en) | 1994-05-18 |
| TW209215B (member.php) | 1993-07-11 |
| KR100252428B1 (ko) | 2000-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |