DE3862901D1 - Thiophenderivat und verfahren zur herstellung. - Google Patents

Thiophenderivat und verfahren zur herstellung.

Info

Publication number
DE3862901D1
DE3862901D1 DE8888305744T DE3862901T DE3862901D1 DE 3862901 D1 DE3862901 D1 DE 3862901D1 DE 8888305744 T DE8888305744 T DE 8888305744T DE 3862901 T DE3862901 T DE 3862901T DE 3862901 D1 DE3862901 D1 DE 3862901D1
Authority
DE
Germany
Prior art keywords
thiophene derivative
production method
integer
zero
oco
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888305744T
Other languages
English (en)
Inventor
Kimiaki Hayashi
Yasuhiko Ozaki
Kenji Yamada
Hideyuki Takenaga
Ichizo Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE3862901D1 publication Critical patent/DE3862901D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C07D333/10Thiophene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Dowels (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8888305744T 1987-06-30 1988-06-23 Thiophenderivat und verfahren zur herstellung. Expired - Fee Related DE3862901D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16483787 1987-06-30

Publications (1)

Publication Number Publication Date
DE3862901D1 true DE3862901D1 (de) 1991-06-27

Family

ID=15800866

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888305744T Expired - Fee Related DE3862901D1 (de) 1987-06-30 1988-06-23 Thiophenderivat und verfahren zur herstellung.

Country Status (16)

Country Link
US (1) US4857543A (de)
EP (1) EP0297782B1 (de)
JP (1) JPS6479175A (de)
KR (1) KR890000457A (de)
CN (1) CN1021051C (de)
AT (1) ATE63746T1 (de)
AU (1) AU599495B2 (de)
CA (1) CA1320964C (de)
DE (1) DE3862901D1 (de)
DK (1) DK358088A (de)
ES (1) ES2040856T3 (de)
FI (1) FI882873A (de)
FR (1) FR2617402B1 (de)
GR (1) GR3001994T3 (de)
HU (1) HU203338B (de)
IL (1) IL86740A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956388A (en) * 1986-12-22 1990-09-11 Eli Lilly And Company 3-aryloxy-3-substituted propanamines
FR2658822A1 (fr) * 1990-02-28 1991-08-30 Jouveinal Sa N-cycloalkylalkylamines, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.
IL97354A (en) * 1990-02-26 1995-12-08 Jouveinal Sa Puril or thianyl-N-cycloalkylalkylamines and pharmaceutical preparations containing them
FR2658817B1 (fr) * 1990-02-28 1993-02-05 Jouveinal Sa Ethylamines substituees, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.
EP0446097A1 (de) * 1990-02-26 1991-09-11 Jouveinal S.A. Substituierte Ethylamine, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Zwischenprodukte zu ihrer Synthese
IE913279A1 (en) * 1990-09-26 1992-04-08 Astra Ab (2-Thienyl)alkylamine Derivatives Having Neuroprotective¹Properties
JPH06509090A (ja) * 1991-07-10 1994-10-13 メルク シヤープ エンド ドーム リミテツド 芳香族化合物、それらを含む組成物、及び治療におけるそれらの使用
GB9211193D0 (en) * 1992-05-27 1992-07-08 Merck Sharp & Dohme Therapeutic agents
CA2415678A1 (en) * 2000-07-13 2003-01-10 Sankyo Company Limited Amino alcohol derivatives
CN100415735C (zh) * 2000-07-13 2008-09-03 三共株式会社 氨基醇衍生物
PT1471054E (pt) 2002-01-11 2009-09-23 Daiichi Sankyo Co Ltd Derivado de aminoálcool ou derivado de ácido fosfónico e composição medicinal que os contém
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물
CN110407703A (zh) * 2019-08-02 2019-11-05 深圳振强生物技术有限公司 吲哚布芬杂质的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3122561A (en) * 1959-10-19 1964-02-25 Tuskegee Inst 1-(2-thenyl)-2-di-lower alkylaminoethyl diphenylacetate and related compounds
GB1343527A (en) * 1971-07-30 1974-01-10 Cerm Cent Europ Rech Mauvernay Amino-propanol derivatives
US4128551A (en) * 1976-12-06 1978-12-05 The Dow Chemical Co. Substituted pyridine carboxyl halides and derivatives
JPS58105946A (ja) * 1981-12-18 1983-06-24 Tanabe Seiyaku Co Ltd アミノブタノ−ルエステル誘導体の製法

Also Published As

Publication number Publication date
IL86740A (en) 1992-11-15
FI882873A0 (fi) 1988-06-16
AU1853488A (en) 1989-01-05
FR2617402A1 (fr) 1989-01-06
DK358088D0 (da) 1988-06-29
JPS6479175A (en) 1989-03-24
JPH0546343B2 (de) 1993-07-13
HUT50160A (en) 1989-12-28
ATE63746T1 (de) 1991-06-15
US4857543A (en) 1989-08-15
CN1021051C (zh) 1993-06-02
KR890000457A (ko) 1989-03-14
EP0297782A1 (de) 1989-01-04
IL86740A0 (en) 1988-11-30
FR2617402B1 (fr) 1991-07-12
EP0297782B1 (de) 1991-05-22
ES2040856T3 (es) 1993-11-01
FI882873A (fi) 1988-12-31
CA1320964C (en) 1993-08-03
AU599495B2 (en) 1990-07-19
HU203338B (en) 1991-07-29
DK358088A (da) 1988-12-31
GR3001994T3 (en) 1992-11-23
CN1030584A (zh) 1989-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee