FR2617402B1 - Derives du thiophene et leur procede de fabrication et medicaments les contenant - Google Patents

Derives du thiophene et leur procede de fabrication et medicaments les contenant

Info

Publication number
FR2617402B1
FR2617402B1 FR888808865A FR8808865A FR2617402B1 FR 2617402 B1 FR2617402 B1 FR 2617402B1 FR 888808865 A FR888808865 A FR 888808865A FR 8808865 A FR8808865 A FR 8808865A FR 2617402 B1 FR2617402 B1 FR 2617402B1
Authority
FR
France
Prior art keywords
manufacturing process
medicaments containing
thiophene derivatives
integer
zero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR888808865A
Other languages
English (en)
Other versions
FR2617402A1 (fr
Inventor
Kimiaki Hayashi
Yasuhiko Ozaki
Kenji Yamada
Hideyuki Takenaga
Ichizo Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2617402A1 publication Critical patent/FR2617402A1/fr
Application granted granted Critical
Publication of FR2617402B1 publication Critical patent/FR2617402B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C07D333/10—Thiophene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Dowels (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
FR888808865A 1987-06-30 1988-06-30 Derives du thiophene et leur procede de fabrication et medicaments les contenant Expired - Fee Related FR2617402B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16483787 1987-06-30

Publications (2)

Publication Number Publication Date
FR2617402A1 FR2617402A1 (fr) 1989-01-06
FR2617402B1 true FR2617402B1 (fr) 1991-07-12

Family

ID=15800866

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888808865A Expired - Fee Related FR2617402B1 (fr) 1987-06-30 1988-06-30 Derives du thiophene et leur procede de fabrication et medicaments les contenant

Country Status (16)

Country Link
US (1) US4857543A (fr)
EP (1) EP0297782B1 (fr)
JP (1) JPS6479175A (fr)
KR (1) KR890000457A (fr)
CN (1) CN1021051C (fr)
AT (1) ATE63746T1 (fr)
AU (1) AU599495B2 (fr)
CA (1) CA1320964C (fr)
DE (1) DE3862901D1 (fr)
DK (1) DK358088A (fr)
ES (1) ES2040856T3 (fr)
FI (1) FI882873A (fr)
FR (1) FR2617402B1 (fr)
GR (1) GR3001994T3 (fr)
HU (1) HU203338B (fr)
IL (1) IL86740A (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956388A (en) * 1986-12-22 1990-09-11 Eli Lilly And Company 3-aryloxy-3-substituted propanamines
FR2658817B1 (fr) * 1990-02-28 1993-02-05 Jouveinal Sa Ethylamines substituees, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.
FR2658822A1 (fr) * 1990-02-28 1991-08-30 Jouveinal Sa N-cycloalkylalkylamines, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.
FI97384C (fi) * 1990-02-26 1996-12-10 Jouveinal Sa Menetelmä terapeuttisesti käyttökelpoisten N-sykloalkyylialkyyliamiinien valmistamiseksi
CA2037123A1 (fr) * 1990-02-26 1991-08-27 Jouveinal S.A. Ethylamines substituees, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese
IE913279A1 (en) * 1990-09-26 1992-04-08 Astra Ab (2-Thienyl)alkylamine Derivatives Having Neuroprotective¹Properties
CA2110725A1 (fr) * 1991-07-10 1993-01-21 Andrew P. Owens Composes aromatiques, compositions en contenant et utilisation en therapeutique
GB9211193D0 (en) * 1992-05-27 1992-07-08 Merck Sharp & Dohme Therapeutic agents
CN100415735C (zh) * 2000-07-13 2008-09-03 三共株式会社 氨基醇衍生物
NZ523554A (en) * 2000-07-13 2004-12-24 Sankyo Co Amino alcohol derivatives
PL211954B1 (pl) 2002-01-11 2012-07-31 Sankyo Co Związek, kompozycja farmaceutyczna oraz zastosowanie kompozycji farmaceutycznej
EP1733724A4 (fr) 2004-02-24 2010-07-07 Sankyo Co Compose d'alcool amine
CN110407703A (zh) * 2019-08-02 2019-11-05 深圳振强生物技术有限公司 吲哚布芬杂质的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3122561A (en) * 1959-10-19 1964-02-25 Tuskegee Inst 1-(2-thenyl)-2-di-lower alkylaminoethyl diphenylacetate and related compounds
GB1343527A (en) * 1971-07-30 1974-01-10 Cerm Cent Europ Rech Mauvernay Amino-propanol derivatives
US4128551A (en) * 1976-12-06 1978-12-05 The Dow Chemical Co. Substituted pyridine carboxyl halides and derivatives
JPS58105946A (ja) * 1981-12-18 1983-06-24 Tanabe Seiyaku Co Ltd アミノブタノ−ルエステル誘導体の製法

Also Published As

Publication number Publication date
KR890000457A (ko) 1989-03-14
EP0297782B1 (fr) 1991-05-22
HU203338B (en) 1991-07-29
CN1021051C (zh) 1993-06-02
US4857543A (en) 1989-08-15
GR3001994T3 (en) 1992-11-23
DK358088A (da) 1988-12-31
AU599495B2 (en) 1990-07-19
CN1030584A (zh) 1989-01-25
EP0297782A1 (fr) 1989-01-04
AU1853488A (en) 1989-01-05
ES2040856T3 (es) 1993-11-01
FR2617402A1 (fr) 1989-01-06
DK358088D0 (da) 1988-06-29
FI882873A0 (fi) 1988-06-16
IL86740A (en) 1992-11-15
CA1320964C (fr) 1993-08-03
DE3862901D1 (de) 1991-06-27
JPS6479175A (en) 1989-03-24
HUT50160A (en) 1989-12-28
JPH0546343B2 (fr) 1993-07-13
IL86740A0 (en) 1988-11-30
ATE63746T1 (de) 1991-06-15
FI882873A (fi) 1988-12-31

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Legal Events

Date Code Title Description
CA Change of address
ST Notification of lapse