ATE170923T1 - Nitratreduktase als marker für acremonium chrysogenum - Google Patents

Nitratreduktase als marker für acremonium chrysogenum

Info

Publication number
ATE170923T1
ATE170923T1 AT90904291T AT90904291T ATE170923T1 AT E170923 T1 ATE170923 T1 AT E170923T1 AT 90904291 T AT90904291 T AT 90904291T AT 90904291 T AT90904291 T AT 90904291T AT E170923 T1 ATE170923 T1 AT E170923T1
Authority
AT
Austria
Prior art keywords
cells
nitrate reductase
pct
marker
gene
Prior art date
Application number
AT90904291T
Other languages
English (en)
Inventor
John Anthony Birkett
James Robert Kinghorn
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE170923T1 publication Critical patent/ATE170923T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/99—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with other acceptors (1.7.99)
    • C12Y107/99004—Nitrate reductase (1.7.99.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/80—Penicillium
    • C12R2001/82—Penicillium chrysogenum

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AT90904291T 1989-03-02 1990-03-02 Nitratreduktase als marker für acremonium chrysogenum ATE170923T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898904762A GB8904762D0 (en) 1989-03-02 1989-03-02 Biological process

Publications (1)

Publication Number Publication Date
ATE170923T1 true ATE170923T1 (de) 1998-09-15

Family

ID=10652592

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90904291T ATE170923T1 (de) 1989-03-02 1990-03-02 Nitratreduktase als marker für acremonium chrysogenum

Country Status (9)

Country Link
US (1) US5302527A (de)
EP (1) EP0414870B1 (de)
JP (1) JP2983058B2 (de)
AT (1) ATE170923T1 (de)
DE (1) DE69032639T2 (de)
DK (1) DK0414870T3 (de)
ES (1) ES2119744T3 (de)
GB (1) GB8904762D0 (de)
WO (1) WO1990010074A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03254684A (ja) * 1990-03-02 1991-11-13 Asahi Chem Ind Co Ltd 新規ｃＤＮＡ化合物
EP0487118A1 (de) * 1990-10-15 1992-05-27 Gist-Brocades N.V. Markierungssystem zur Transformationsselektion geeignet für Penicillium
EP0566897A3 (en) * 1992-04-07 1994-07-06 Hoechst Ag The complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use
EP0635574B1 (de) * 1993-07-23 2003-04-23 Dsm N.V. Selektionmarker-genfreie rekombinante Stämme: Verfahren zur ihrer Herstellung und die Verwendung dieser Stämme
JP3619282B2 (ja) * 1994-04-01 2005-02-09 中外製薬株式会社 ＩｇＧＦｃ部結合タンパク質をコードする遺伝子
EP1559776A3 (de) * 1994-06-30 2006-01-11 Novozymes Biotech, Inc. Nicht-toxisches, nicht-toxigenes, nicht-pathogenes Fusarium Expressionssystem und darin zu verwendende Promotoren und Terminatoren
FR2723589B1 (fr) * 1994-08-12 1996-09-20 Bio Merieux Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagas
US6001600A (en) * 1996-12-20 1999-12-14 Smithkline Beecham Plc DNA encoding tests polypeptides
US6010881A (en) * 1996-02-20 2000-01-04 Smithkline Beecham Corporation RibG
GB9607999D0 (en) * 1996-04-18 1996-06-19 Smithkline Beecham Plc Novel compounds
EP0956289A4 (de) * 1996-08-16 2004-10-13 Smithkline Beecham Corp Prokaryotische polynucleotide, polypeptide und ihre verwendung
CA2263141A1 (en) * 1996-08-23 1998-02-26 North Carolina State University Neutralization-sensitive epitopes of cryptosporidium parvum
US6887663B1 (en) * 1996-10-31 2005-05-03 Human Genome Sciences, Inc. Streptococcus pneumoniae SP036 polynucleotides
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
US6383774B1 (en) * 1996-12-03 2002-05-07 Heska Corporation Parasitic nematode transglutaminase, nucleic acid molecules and uses thereof
CA2288974A1 (en) * 1997-04-15 1998-10-22 Eli Lilly And Company Ipc synthase genes from fungi
US5952196A (en) * 1997-04-18 1999-09-14 Smithkline Beecham Plc Prolyl tRNA synthetase polynucleotides
US5958733A (en) * 1997-04-18 1999-09-28 Smithkline Beecham Plc Threonyl tRNA synthetase polynucleotides
US6485904B1 (en) * 1997-06-23 2002-11-26 Pfizer, Inc. DNA encoding a plasminogen activating protein
US7153952B1 (en) 1997-07-02 2006-12-26 sanofi pasteur limited/sanofi pasteur limitée Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
CA2315880A1 (en) * 1997-12-31 1999-07-15 Stressgen Biotechnologies Corporation Streptococcal heat shock proteins of the hsp60 family
US6306623B1 (en) * 1998-02-24 2001-10-23 The University Of California Leptospiral major outer membrane protein LipL32
JP2002516068A (ja) * 1998-03-20 2002-06-04 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ遺伝子およびポリペプチド
ATE395424T1 (de) * 1998-05-20 2008-05-15 Novozymes Inc Verfahren zur herstellung von heterologen polypeptiden in trichothecene mangelmutanten filamentlösen pilzen
WO2000004923A1 (en) * 1998-07-23 2000-02-03 Smithkline Beecham Corporation Scrp-5: secreted cysteine rich protein-5
US6649370B1 (en) * 1998-10-28 2003-11-18 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US7026156B1 (en) * 1999-02-04 2006-04-11 The University Of Georgia Research Foundation, Inc. Diagnostic and protective antigen gene sequences of ichthyophthirius
SE515819C2 (sv) * 1999-02-25 2001-10-15 Statens Veterinaermedicinska A Protein från kvalstret Sarcoptes scabiei
US6582950B1 (en) * 1999-10-04 2003-06-24 Regents Of The University Of Minnesota C3 binding polypeptide of Streptococcus agalactiae group b Streptococcus
GB0008748D0 (en) * 2000-04-11 2000-05-31 Univ Manchester Mutant bank
US20030199603A1 (en) * 2002-04-04 2003-10-23 3M Innovative Properties Company Cured compositions transparent to ultraviolet radiation
US7172868B2 (en) * 2002-08-01 2007-02-06 The Regents Of The University Of California Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis
CA2532024A1 (en) * 2003-07-11 2005-01-20 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from staphylococcus aureus
US7073678B1 (en) * 2003-08-04 2006-07-11 Helen Of Troy Limited Travel beverage container
US7550576B2 (en) * 2004-08-09 2009-06-23 North Carolina State University Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
JP4886784B2 (ja) * 2005-09-27 2012-02-29 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティド バイ ザ セクレタリー オブ ザ ディパートメント オブ ヘルス アンド ヒューマン サービシズ， センターズ カンジダ種の検出のための組成物および方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8508800D0 (en) * 1985-04-04 1985-05-09 Glaxo Group Ltd Microbiological process
PT83621B (en) * 1985-10-28 1988-03-02 Gen Hospital Corp Method for producing polynucleotides coding for nitrate reductase
DK173292B1 (da) * 1986-01-31 2000-06-13 Antibioticos Sa Fremgangsmåde til selekterbar transformation af Pencillium chrysogenum, plasmider til anvendelse ved fremgangsmåden samt P.
EP0233715B1 (de) * 1986-01-31 1994-05-25 BEECHAM GROUP plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen

Also Published As

Publication number Publication date
ES2119744T3 (es) 1998-10-16
EP0414870B1 (de) 1998-09-09
JPH03504334A (ja) 1991-09-26
WO1990010074A1 (en) 1990-09-07
DK0414870T3 (da) 1999-06-07
DE69032639D1 (en) 1998-10-15
GB8904762D0 (en) 1989-04-12
JP2983058B2 (ja) 1999-11-29
DE69032639T2 (de) 1999-01-28
EP0414870A1 (de) 1991-03-06
US5302527A (en) 1994-04-12

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee