ATE169632T1 - Nukleinsäureanaloga mit chelatisierender funktionalität - Google Patents
Nukleinsäureanaloga mit chelatisierender funktionalitätInfo
- Publication number
- ATE169632T1 ATE169632T1 AT95902082T AT95902082T ATE169632T1 AT E169632 T1 ATE169632 T1 AT E169632T1 AT 95902082 T AT95902082 T AT 95902082T AT 95902082 T AT95902082 T AT 95902082T AT E169632 T1 ATE169632 T1 AT E169632T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- acid analogues
- chelating functionality
- analog
- chelating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C07K14/003—Peptide-nucleic acids (PNAs)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9324243A GB2284208A (en) | 1993-11-25 | 1993-11-25 | Nucleic acid analogues with a chelating functionality for metal ions |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE169632T1 true ATE169632T1 (de) | 1998-08-15 |
Family
ID=10745682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95902082T ATE169632T1 (de) | 1993-11-25 | 1994-11-22 | Nukleinsäureanaloga mit chelatisierender funktionalität |
Country Status (14)
Country | Link |
---|---|
US (2) | US5843663A (de) |
EP (1) | EP0730602B1 (de) |
JP (1) | JPH09504050A (de) |
KR (1) | KR0169873B1 (de) |
AT (1) | ATE169632T1 (de) |
AU (1) | AU684118B2 (de) |
CA (1) | CA2176745C (de) |
DE (1) | DE69412509T2 (de) |
DK (1) | DK0730602T3 (de) |
ES (1) | ES2122516T3 (de) |
GB (1) | GB2284208A (de) |
IL (1) | IL111733A (de) |
WO (1) | WO1995014708A1 (de) |
ZA (1) | ZA949317B (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6133444A (en) * | 1993-12-22 | 2000-10-17 | Perseptive Biosystems, Inc. | Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions |
US6919441B2 (en) | 1994-03-14 | 2005-07-19 | Aventis Pharma Deutschland Gmbh | Polyamide-oligonucleotide derivatives, their preparation and use |
DE69632324T2 (de) * | 1995-06-07 | 2005-06-16 | PerSeptive Biosystems, Inc., Framingham | Pna-dna-chimäre und pna-synthone zu deren herstellung |
CA2190430A1 (en) * | 1995-12-12 | 1997-06-13 | Margret Barbara Basinski | Method for measuring genetic messages |
US5763424A (en) * | 1996-03-26 | 1998-06-09 | Gilead Sciences, Inc. | Composition and method for storing nucleotide analogs |
AU739391B2 (en) * | 1996-07-03 | 2001-10-11 | President And Fellows Of Harvard College | Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides |
DE19712530A1 (de) | 1997-03-25 | 1998-10-01 | Boehringer Mannheim Gmbh | Neue Monomerbausteine zur Markierung von peptidischen Nukleinsäuren |
US6617422B1 (en) | 1997-05-23 | 2003-09-09 | Peter Nielsen | Peptide nucleic acid monomers and oligomers |
US6914137B2 (en) * | 1997-12-06 | 2005-07-05 | Dna Research Innovations Limited | Isolation of nucleic acids |
DE19757516A1 (de) * | 1997-12-23 | 1999-06-24 | Roche Diagnostics Gmbh | Modifizierte Nukleinsäureanaloga |
AU2862100A (en) * | 1999-01-27 | 2000-08-18 | Folim G. Halaka | Materials and methods for the purification of polyelectrolytes |
DE60045350D1 (de) | 1999-06-01 | 2011-01-20 | Baylor College Medicine | Zusammensetzungen und verfahren zur therapeutischen anwendung einer mit dem gen atonal assoziierten sequenz |
CA2382545C (en) * | 1999-08-27 | 2013-08-13 | Phylos, Inc. | Methods for encoding and sorting in vitro translated proteins |
US6348583B1 (en) * | 1999-08-30 | 2002-02-19 | Bio-Rad Laboratories, Inc. | Poly(ether-thioether), poly(ether-sulfoxide) and poly(ether-sulfone) nucleic acids |
DK1325125T3 (da) | 2000-07-10 | 2013-09-08 | Univ Texas | Tumorundertrykkende gener af chromosomerne 3P21.3 |
US20060073530A1 (en) * | 2001-08-15 | 2006-04-06 | Olaf Schneewind | Methods and compositions involving sortase B |
JP2005515468A (ja) * | 2001-08-20 | 2005-05-26 | リジェネシス バイオリメディエイション プロダクツ | 微分子の分析物のバイオセンサ |
US20050053939A1 (en) * | 2001-11-09 | 2005-03-10 | Ahmed Chenna | Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents |
US8110351B2 (en) | 2002-01-16 | 2012-02-07 | Invitrogen Dynal As | Method for isolating nucleic acids and protein from a single sample |
EP2269618A1 (de) | 2002-08-12 | 2011-01-05 | Jennerex Biotherapeutics ULC | Ein onkolytisches Vaccinia-Virus zur Verwendung in Kombination mit Chemotherapie zur Behandlung von Krebs |
US20050009051A1 (en) * | 2002-09-27 | 2005-01-13 | Board Of Regents, The University Of Texas | Diagnosis of mould infection |
KR101152561B1 (ko) * | 2002-09-27 | 2012-06-01 | 파우더젝트 리서치 리미티드 | 핵산 코팅된 입자 |
US20050123932A1 (en) * | 2003-12-09 | 2005-06-09 | Mekbib Astatke | Nucleic acid-chelating agent conjugates |
US7897378B2 (en) | 2004-03-18 | 2011-03-01 | Roche Molecular Systems, Inc. | Method and device for purifying nucleic acids |
US20050241959A1 (en) * | 2004-04-30 | 2005-11-03 | Kenneth Ward | Chemical-sensing devices |
WO2005118858A1 (en) * | 2004-05-28 | 2005-12-15 | Board Of Regents, The University Of Texas System | Multigene predictors of response to chemotherapy |
ES2345993T3 (es) | 2004-09-14 | 2010-10-07 | The Regents Of The University Of Colorado, A Body Corporate | Metodo para el tratamiento con bucindolol basado en direccionamiento genetico. |
KR20090004839A (ko) | 2005-09-07 | 2009-01-12 | 제네렉스, 인코포레이티드 | Gm-csf를 발현하는 폭스바이러스를 사용한 전이성및/또는 전신 파종성 암의 전신 치료법 |
US8980246B2 (en) | 2005-09-07 | 2015-03-17 | Sillajen Biotherapeutics, Inc. | Oncolytic vaccinia virus cancer therapy |
EP2839837B1 (de) | 2006-09-15 | 2019-05-08 | Children's Hospital of Eastern Ontario Research Institute Inc. | Onkolytisches farmington rhabdovirus |
US20080269065A1 (en) * | 2007-04-30 | 2008-10-30 | Syntrix Biosystems, Inc. | Conformationally Constrained Analytical Probes |
EP2055385B1 (de) | 2007-10-31 | 2010-05-26 | Roche Diagnostics GmbH | Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren |
US20090162845A1 (en) | 2007-12-20 | 2009-06-25 | Elazar Rabbani | Affinity tag nucleic acid and protein compositions, and processes for using same |
ES2744797T3 (es) | 2008-02-29 | 2020-02-26 | Univ Oxford Innovation Ltd | Procedimiento de determinación de una dosis adecuada de estatina |
GB0804495D0 (en) * | 2008-03-11 | 2008-04-16 | Iti Scotland Ltd | Surface attachment |
US9817001B2 (en) | 2008-05-27 | 2017-11-14 | Boston Heart Diagnostics Corporation | Methods for determining LDL cholesterol treatment |
US8470541B1 (en) | 2008-09-27 | 2013-06-25 | Boston Heart Diagnostics Corporation | Methods for separation and immuno-detection of biomolecules, and apparatus related thereto |
US9409983B2 (en) | 2009-07-23 | 2016-08-09 | The Board Of Trustess Of The University Of Illinois | Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases |
US9512481B2 (en) | 2009-09-11 | 2016-12-06 | The Regents Of The University Of Colorado, A Body Corporate | Polymorphisms in the PDE3A gene |
BR112012005774B8 (pt) | 2009-09-14 | 2023-02-14 | Jennerex Inc | uso de um inibidor de quinase antiangiogênico no tratamento de câncer |
MX337062B (es) | 2009-12-10 | 2016-02-11 | Ottawa Hospital Res Inst | Rabdovirus oncolítico. |
WO2011079273A2 (en) | 2009-12-23 | 2011-06-30 | Arca Biopharma, Inc. | Methods and compositions for cardiovascular diseases and conditions |
CN103429258B (zh) | 2011-01-04 | 2016-03-09 | 新罗杰公司 | 通过施用溶瘤痘苗病毒生成针对肿瘤抗原的抗体和生成肿瘤特异性补体依赖性细胞毒性 |
CA2828532A1 (en) | 2011-02-28 | 2012-11-22 | University Of Iowa Research Foundation | Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender |
AU2012226530B2 (en) | 2011-03-08 | 2016-12-01 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
CA2872045A1 (en) | 2011-06-08 | 2012-12-13 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Compositions and methods for glioblastoma treatment |
US10040853B2 (en) | 2011-09-09 | 2018-08-07 | Fred Hutchinson Cancer Research Center | Methods and compositions involving NKG2D inhibitors and cancer |
EP3324184A1 (de) | 2011-10-13 | 2018-05-23 | Boston Heart Diagnostics | Zusammensetzungen und verfahren zur behandlung und prävention von koronarer herzkrankheit |
WO2014116721A1 (en) | 2013-01-22 | 2014-07-31 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
CA2901501C (en) | 2013-02-21 | 2023-03-07 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Vaccine composition |
US9828624B2 (en) | 2013-07-24 | 2017-11-28 | Boston Heart Diagnostics Corporation | Driving patient compliance with therapy |
CA2968221A1 (en) | 2014-11-17 | 2016-05-26 | Boston Heart Diagnostic Corporation | Cardiovascular disease risk assessment |
US20180057839A1 (en) | 2014-11-26 | 2018-03-01 | The Regents Of The University Of California | Therapeutic compositions comprising transcription factors and methods of making and using the same |
CA3117112A1 (en) | 2018-10-31 | 2020-05-07 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Biomarkers and methods of use for radiation-induced lung injury |
CN112876580B (zh) * | 2021-03-11 | 2022-12-27 | 山西奥睿基赛生物科技有限公司 | 一种腐殖酸去除剂、其制备方法及应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4707440A (en) * | 1984-01-30 | 1987-11-17 | Enzo Biochem, Inc. | Nucleic acid hybridization assay and detectable molecules useful in such assay |
US5166315A (en) * | 1989-12-20 | 1992-11-24 | Anti-Gene Development Group | Sequence-specific binding polymers for duplex nucleic acids |
CA1340522C (en) * | 1987-03-10 | 1999-05-04 | Heinz Dobeli | Fusion proteins containing neighbouring histidines for improved purification |
WO1993024511A1 (en) * | 1992-05-29 | 1993-12-09 | Howard Florey Institute Of Experimental Physiology And Medicine | Oligonucleotide-polyamide conjugates |
EP0525181B1 (de) * | 1991-02-14 | 1997-08-06 | Dade MicroScan Inc. | Neue oligonukleotide konjugiert zu lanthanide-chelaten |
WO1992021151A2 (en) * | 1991-05-10 | 1992-11-26 | Q-Dot, Inc. | HIGH-SPEED PERISTALTIC CCD IMAGER WITH GaAs FET OUTPUT |
DK51092D0 (da) * | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
US5539082A (en) * | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
DK0529175T3 (da) * | 1991-07-22 | 1995-11-06 | Bracco Int Bv | Konjugater chelaret med paramagnetiske metaller til målsøgning |
US5326856A (en) * | 1992-04-09 | 1994-07-05 | Cytogen Corporation | Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding |
-
1993
- 1993-11-25 GB GB9324243A patent/GB2284208A/en not_active Withdrawn
-
1994
- 1994-11-22 AT AT95902082T patent/ATE169632T1/de not_active IP Right Cessation
- 1994-11-22 ES ES95902082T patent/ES2122516T3/es not_active Expired - Lifetime
- 1994-11-22 DK DK95902082T patent/DK0730602T3/da active
- 1994-11-22 KR KR1019960702729A patent/KR0169873B1/ko not_active IP Right Cessation
- 1994-11-22 WO PCT/EP1994/003859 patent/WO1995014708A1/en active IP Right Grant
- 1994-11-22 IL IL11173394A patent/IL111733A/en not_active IP Right Cessation
- 1994-11-22 CA CA002176745A patent/CA2176745C/en not_active Expired - Fee Related
- 1994-11-22 DE DE69412509T patent/DE69412509T2/de not_active Expired - Lifetime
- 1994-11-22 EP EP95902082A patent/EP0730602B1/de not_active Expired - Lifetime
- 1994-11-22 JP JP7514829A patent/JPH09504050A/ja active Pending
- 1994-11-22 AU AU11075/95A patent/AU684118B2/en not_active Ceased
- 1994-11-24 ZA ZA949317A patent/ZA949317B/xx unknown
-
1996
- 1996-05-24 US US08/653,607 patent/US5843663A/en not_active Expired - Lifetime
-
1998
- 1998-05-29 US US09/086,726 patent/US6346378B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ZA949317B (en) | 1996-05-24 |
ES2122516T3 (es) | 1998-12-16 |
DK0730602T3 (da) | 1999-05-10 |
US20010047077A1 (en) | 2001-11-29 |
GB2284208A (en) | 1995-05-31 |
US5843663A (en) | 1998-12-01 |
KR960705836A (ko) | 1996-11-08 |
GB9324243D0 (en) | 1994-01-12 |
IL111733A0 (en) | 1995-01-24 |
EP0730602B1 (de) | 1998-08-12 |
WO1995014708A1 (en) | 1995-06-01 |
IL111733A (en) | 2001-07-24 |
JPH09504050A (ja) | 1997-04-22 |
EP0730602A1 (de) | 1996-09-11 |
KR0169873B1 (ko) | 1999-01-15 |
CA2176745C (en) | 2004-05-25 |
AU1107595A (en) | 1995-06-13 |
AU684118B2 (en) | 1997-12-04 |
CA2176745A1 (en) | 1995-06-01 |
DE69412509T2 (de) | 1999-01-28 |
US6346378B2 (en) | 2002-02-12 |
DE69412509D1 (de) | 1998-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |