ATE160339T1 - Benzimidazolderivate, verfahren zur herstellung, zwischenprodukte, und diese als aktive bestandteile enthaltende antiemetische substanzen - Google Patents

Benzimidazolderivate, verfahren zur herstellung, zwischenprodukte, und diese als aktive bestandteile enthaltende antiemetische substanzen

Info

Publication number
ATE160339T1
ATE160339T1 AT92913261T AT92913261T ATE160339T1 AT E160339 T1 ATE160339 T1 AT E160339T1 AT 92913261 T AT92913261 T AT 92913261T AT 92913261 T AT92913261 T AT 92913261T AT E160339 T1 ATE160339 T1 AT E160339T1
Authority
AT
Austria
Prior art keywords
antiemetic
production
active ingredients
intermediate products
substances containing
Prior art date
Application number
AT92913261T
Other languages
English (en)
Inventor
Kenji Suzuki
Hiroshi Ohtaka
Akio Ozaki
Yasuo Morimoto
Takayuki Sukamoto
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP18929591A external-priority patent/JP2895665B2/ja
Priority claimed from JP3357558A external-priority patent/JPH05170745A/ja
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Application granted granted Critical
Publication of ATE160339T1 publication Critical patent/ATE160339T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT92913261T 1991-07-02 1992-06-22 Benzimidazolderivate, verfahren zur herstellung, zwischenprodukte, und diese als aktive bestandteile enthaltende antiemetische substanzen ATE160339T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18929591A JP2895665B2 (ja) 1991-07-02 1991-07-02 ベンズイミダゾール誘導体、その製造法およびその製造用中間体
JP3357558A JPH05170745A (ja) 1991-12-25 1991-12-25 ベンズイミダゾール誘導体、その製造法、それを有効成分とする制吐剤およびその製造用中間体

Publications (1)

Publication Number Publication Date
ATE160339T1 true ATE160339T1 (de) 1997-12-15

Family

ID=26505402

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92913261T ATE160339T1 (de) 1991-07-02 1992-06-22 Benzimidazolderivate, verfahren zur herstellung, zwischenprodukte, und diese als aktive bestandteile enthaltende antiemetische substanzen

Country Status (10)

Country Link
US (1) US5407936A (de)
EP (1) EP0641784B1 (de)
KR (1) KR100188575B1 (de)
AT (1) ATE160339T1 (de)
DE (1) DE69223262T2 (de)
DK (1) DK0641784T3 (de)
ES (1) ES2111070T3 (de)
GR (1) GR3025451T3 (de)
TW (1) TW201744B (de)
WO (1) WO1993001176A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09315976A (ja) * 1996-05-29 1997-12-09 Nitto Denko Corp 経皮投与用製剤
JPH09323934A (ja) * 1996-05-31 1997-12-16 Kanebo Ltd 保存安定性の改善された坐剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50126682A (de) * 1974-03-25 1975-10-04
US4093726A (en) * 1976-12-02 1978-06-06 Abbott Laboratories N-(2-benzimidazolyl)-piperazines
JPH01242574A (ja) * 1988-03-25 1989-09-27 Ube Ind Ltd 含窒素縮合環を有するピペリジン及びピペラジン誘導体、その製造方法並びにそれを含む薬学的組成物
ES2038532B1 (es) * 1991-05-10 1994-02-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de 2-piperacinilbecimidazol.

Also Published As

Publication number Publication date
KR940701387A (ko) 1994-05-28
TW201744B (de) 1993-03-11
ES2111070T3 (es) 1998-03-01
US5407936A (en) 1995-04-18
DE69223262T2 (de) 1998-04-16
WO1993001176A1 (en) 1993-01-21
EP0641784B1 (de) 1997-11-19
EP0641784A4 (de) 1994-03-02
KR100188575B1 (ko) 1999-06-01
EP0641784A1 (de) 1995-03-08
DK0641784T3 (da) 1998-07-27
GR3025451T3 (en) 1998-02-27
DE69223262D1 (de) 1998-01-02

Similar Documents

Publication Publication Date Title
NO900306D0 (no) Fremgangsmaate for fremstilling av nye pyrazolopyridin-forbindelser.
DE59203704D1 (de) Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung.
HUT56370A (en) Process for producing tricyclic carbapenem derivatives and pharmaceutical compositions comprising such compounds as active ingredient
ATE338754T1 (de) Heterocyclische verbindungen, ihre herstellung und verwendung
HUT54357A (en) Process for producing benzilidene-(azolylmethyl)-cycloalkane and -cycloalkene derivatives, fungicidal compositions comprising such compounds as active ingredient and intermediates usable for the production of the active ingredients
DE69428142D1 (de) Quinolin- oder Quinazolinderivate, deren Herstellung und Verwendung
HUT59394A (en) Process for producing piperazine derivatives and pharmaceutical compositions comprising same
FI944823A (fi) Galantamiinijohdannaisia, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineissa
ATE160339T1 (de) Benzimidazolderivate, verfahren zur herstellung, zwischenprodukte, und diese als aktive bestandteile enthaltende antiemetische substanzen
DE69329184D1 (de) Alkylsubstituierte heterocyclische Verbindungen
MX15697A (es) Derivados heterotetraciclicos de lactama y procesopara su preparacion
ATE160566T1 (de) Amphotere tricyclische verbindungen als antihistaminische und antiallergische mittel
ES2096800T3 (es) Benzo(b)tiofen-3-il-piperazinas, un procedimiento para su preparacion y su uso como medicamentos.
HUT60261A (en) Process for producing piperazine derivatives and pharmaceutical compositions comprising same
MX25922A (es) Pirido (3,4-b) pirrolo (1,2-e)(1,4,5)oxadiazepinasy compuestos analogos relacionados un procedimiento para su preparacion y su uso como medicamentos
ITMI920082A1 (it) Derivati solforati di acidi biliari
ATE208761T1 (de) Quinolin-derivate und diese enthaltende pharmazeutische zusammensetzungen
TH17758A (th) สารเคมี
ATE1585T1 (de) Clavulansaeurederivate, ihre herstellung und sie enthaltende pharmazeutische praeparate.
TH11701EX (th) สารประกอบเฮเทโรไซคลิคที่ใช้ในการรักษาโรค

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee