ATE153031T1 - Peptid für die stimulierung von für hepatitis c virus spesifischen cytotoischen t lymphozyten - Google Patents
Peptid für die stimulierung von für hepatitis c virus spesifischen cytotoischen t lymphozytenInfo
- Publication number
- ATE153031T1 ATE153031T1 AT93915244T AT93915244T ATE153031T1 AT E153031 T1 ATE153031 T1 AT E153031T1 AT 93915244 T AT93915244 T AT 93915244T AT 93915244 T AT93915244 T AT 93915244T AT E153031 T1 ATE153031 T1 AT E153031T1
- Authority
- AT
- Austria
- Prior art keywords
- virus
- peptide
- ctl
- hepatitis
- recognize
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 241000711549 Hepacivirus C Species 0.000 title abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 230000004936 stimulating effect Effects 0.000 title 1
- 108700018351 Major Histocompatibility Complex Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 abstract 2
- 238000011725 BALB/c mouse Methods 0.000 abstract 1
- 241001227713 Chiron Species 0.000 abstract 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 1
- 102000008949 Histocompatibility Antigens Class I Human genes 0.000 abstract 1
- 108010088652 Histocompatibility Antigens Class I Proteins 0.000 abstract 1
- 108010076039 Polyproteins Proteins 0.000 abstract 1
- 230000005867 T cell response Effects 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 1
- 210000003494 hepatocyte Anatomy 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/894,063 US5980899A (en) | 1992-06-10 | 1992-06-10 | Identification of peptides that stimulate hepatitis C virus specific cytotoxic T cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE153031T1 true ATE153031T1 (de) | 1997-05-15 |
Family
ID=25402543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93915244T ATE153031T1 (de) | 1992-06-10 | 1993-06-10 | Peptid für die stimulierung von für hepatitis c virus spesifischen cytotoischen t lymphozyten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5980899A (de) |
| EP (1) | EP0644894B1 (de) |
| JP (1) | JP3510249B2 (de) |
| AT (1) | ATE153031T1 (de) |
| AU (1) | AU669193B2 (de) |
| CA (1) | CA2135278C (de) |
| DE (1) | DE69310734T2 (de) |
| DK (1) | DK0644894T3 (de) |
| ES (1) | ES2104156T3 (de) |
| GR (1) | GR3024462T3 (de) |
| WO (1) | WO1993025575A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639594A (en) * | 1990-02-16 | 1997-06-17 | United Biomedical, Inc. | Linear and branched peptides effective in diagnosing and detecting non-A, non-B hepatitis |
| US5582968A (en) * | 1990-02-16 | 1996-12-10 | United Biomedical, Inc. | Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis |
| US5709995A (en) | 1994-03-17 | 1998-01-20 | The Scripps Research Institute | Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses |
| AU773000C (en) * | 1994-07-27 | 2004-10-07 | Csl Limited | Polyepitope vaccines |
| WO1996003144A1 (en) * | 1994-07-27 | 1996-02-08 | The Council Of The Queensland Institute Of Medical Research | Polyepitope vaccines |
| US5767233A (en) * | 1995-05-12 | 1998-06-16 | Schering Corporation | Soluble cleavable substrates of the hepatitis C virus protease |
| GB9618119D0 (en) | 1996-08-30 | 1996-10-09 | Univ Southampton | Adjuvants for use in vaccines |
| JP2001526028A (ja) | 1997-12-11 | 2001-12-18 | スミスクライン・ビーチャム・コーポレイション | Ｃ型肝炎ウイルスｎｓ５ｂ末端切断タンパク質およびその抗ウイルス化合物同定方法 |
| JP2003509465A (ja) * | 1999-07-19 | 2003-03-11 | エピミューン， インコーポレイテッド | ペプチドおよび核酸組成物を使用する、ｃ型肝炎ウイルスに対する細胞性免疫応答の誘導 |
| BR0108210A (pt) | 2000-02-04 | 2002-10-22 | Univ Duke | Vacina contra o vìrus da imunodeficiência humana |
| WO2001072331A1 (en) * | 2000-03-31 | 2001-10-04 | Vaccine Chip Technology Aps | Immunostimulating properties of a fragment of tgf-beta |
| ATE502952T1 (de) * | 2000-09-01 | 2011-04-15 | Epimmune Inc | Hla-bindungspeptide und ihre anwendungszwecke |
| AU2002259130A1 (en) * | 2001-05-03 | 2002-11-18 | Eli Lilly And Company | Agents for treatment of hcv and methods of use |
| FR2828934B1 (fr) * | 2001-08-27 | 2004-08-13 | Inst Nat Sante Rech Med | Test de l'immunite cellulaire par des peptides fixes sur support solide |
| EP1357127A1 (de) * | 2002-04-10 | 2003-10-29 | Immusystems GmbH | CD4+ T-Lymphozyten spezifische Hepatitis C Virus-Epitope |
| CA2566506A1 (en) * | 2004-06-01 | 2005-12-15 | Innogenetics N.V. | Peptides for inducing a ctl and/or htl response to hepatitis c virus |
| CA2624153A1 (en) * | 2005-09-29 | 2007-04-12 | The Scripps Research Institute | Viral peptides and their use to inhibit viral infections against viruses of the flaviridae family |
| EP1989326A4 (de) | 2006-01-17 | 2009-09-30 | Health Research Inc | Heteroduplex-verfolgungstest |
| AU2019233861A1 (en) * | 2018-03-16 | 2020-10-01 | The Governors Of The University Of Alberta | Hepatitis C virus peptide compositions and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861588A (en) * | 1985-02-05 | 1989-08-29 | New York Blood Center, Inc. | Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers |
| US4879213A (en) * | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
| NZ227011A (en) * | 1987-11-18 | 1992-03-26 | Chiron Corp | Non-a, non-b-hepatitis (hepatitis c) antigens, proteins, nucleotide sequences, vaccines and kits |
| CA2047792C (en) * | 1990-07-26 | 2002-07-02 | Chang Y. Wang | Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines |
-
1992
- 1992-06-10 US US07/894,063 patent/US5980899A/en not_active Expired - Fee Related
-
1993
- 1993-06-10 CA CA002135278A patent/CA2135278C/en not_active Expired - Fee Related
- 1993-06-10 AU AU45300/93A patent/AU669193B2/en not_active Ceased
- 1993-06-10 DK DK93915244.3T patent/DK0644894T3/da active
- 1993-06-10 JP JP50165694A patent/JP3510249B2/ja not_active Expired - Fee Related
- 1993-06-10 EP EP93915244A patent/EP0644894B1/de not_active Expired - Lifetime
- 1993-06-10 AT AT93915244T patent/ATE153031T1/de not_active IP Right Cessation
- 1993-06-10 ES ES93915244T patent/ES2104156T3/es not_active Expired - Lifetime
- 1993-06-10 WO PCT/US1993/005434 patent/WO1993025575A1/en active IP Right Grant
- 1993-06-10 DE DE69310734T patent/DE69310734T2/de not_active Expired - Fee Related
-
1997
- 1997-08-14 GR GR970402100T patent/GR3024462T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0644894T3 (da) | 1997-12-08 |
| WO1993025575A1 (en) | 1993-12-23 |
| DE69310734T2 (de) | 1998-01-15 |
| GR3024462T3 (en) | 1997-11-28 |
| CA2135278C (en) | 2005-08-09 |
| DE69310734D1 (de) | 1997-06-19 |
| JP3510249B2 (ja) | 2004-03-22 |
| EP0644894B1 (de) | 1997-05-14 |
| CA2135278A1 (en) | 1993-12-23 |
| AU669193B2 (en) | 1996-05-30 |
| JPH08501282A (ja) | 1996-02-13 |
| AU4530093A (en) | 1994-01-04 |
| ES2104156T3 (es) | 1997-10-01 |
| US5980899A (en) | 1999-11-09 |
| EP0644894A1 (de) | 1995-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE153031T1 (de) | Peptid für die stimulierung von für hepatitis c virus spesifischen cytotoischen t lymphozyten | |
| Rottier et al. | Predicted membrane topology of the coronavirus protein E1 | |
| KR960704923A (ko) | HIV에 대한 면역응답을 유도할 수 있는 펩티드 및 그 펩티드를 함유하는 항 AIDS 예방·치료제(Peptides Capable of Inducing Immune Response to HIV and Anti-AIDS Agent for Preventing and Curing AIDS) | |
| Kanai et al. | Poly (U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase | |
| Mizushima et al. | Analysis of N-terminal processing of hepatitis C virus nonstructural protein 2 | |
| Kurokohchi et al. | Use of recombinant protein to identify a motif-negative human cytotoxic T-cell epitope presented by HLA-A2 in the hepatitis C virus NS3 region | |
| Hirowatari et al. | Two proteinase activities in HCV polypeptide expressed in insect cells using baculovirus vector | |
| IL133056A0 (en) | A polypeptide containing an immunogenic portion of a m tuberculosis antigen a variant thereof pharmaceutical compositions vaccines and kits containing same | |
| DE3584260D1 (de) | Die synthese eines proteins mittels eines identifizierungspeptids. | |
| RU2004126135A (ru) | Новый цитокин zalpha11-лиганд | |
| JP2007516696A5 (de) | ||
| NZ319786A (en) | HCV NS3 protein fragments with helicase activity and improved solubility | |
| CA2389206A1 (en) | Activation of hcv-specific t cells | |
| KR940703860A (ko) | 신규한 사람 쿠니즈형 프로테아제 저해제 및 그의 변이체(a novel human kunitz-type protease inhibitor and variants thereof) | |
| KR900016261A (ko) | 독사독 폴리펩티드 및 유전적 발현 | |
| Kane et al. | Cytolytic T-lymphocyte response to isolated class IH–2 proteins and influenza peptides | |
| BR0309401A (pt) | polinucleotìdeo isolado, vetor de expressão, célula cultivada, método para produzir polipeptìdeos, e um anticorpo para um polipeptìdeo, e, anticorpo | |
| MY135991A (en) | A vaccine-induced hepatits b viral strain and uses thereof | |
| GR3027636T3 (en) | Anti-feline immunodeficiency virus (fiv) vaccines. | |
| US5026686A (en) | Antiviral peptides | |
| NO20006456L (no) | En mutant human hepatitt B viral stamme og anvendelser derav | |
| EP0501557A1 (de) | Mit Antikörper gegen Hepatitis non-A, non-B-Virus immunochemische reaktive Peptide | |
| Pearson et al. | Predicted Membrane Topology of the Coronavirus Protein El | |
| PT89041A (pt) | Metodo de preparacao de diagnosticos e vacinas nanbv | |
| 黎孟枫 et al. | Cloning, Sequencing and Expression in E. coli of Interferon-ω1 Gene |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |