ATE150793T1 - Markierte verbindungen zur verwendung in einem diagnostischen atemtest - Google Patents
Markierte verbindungen zur verwendung in einem diagnostischen atemtestInfo
- Publication number
- ATE150793T1 ATE150793T1 AT91911157T AT91911157T ATE150793T1 AT E150793 T1 ATE150793 T1 AT E150793T1 AT 91911157 T AT91911157 T AT 91911157T AT 91911157 T AT91911157 T AT 91911157T AT E150793 T1 ATE150793 T1 AT E150793T1
- Authority
- AT
- Austria
- Prior art keywords
- microorganisms
- breath test
- oils
- produce
- labeled
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003921 oil Substances 0.000 abstract 5
- 244000005700 microbiome Species 0.000 abstract 4
- 239000000758 substrate Substances 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005642 Oleic acid Substances 0.000 abstract 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1206—Administration of radioactive gases, aerosols or breath tests
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/946—Microorganisms using algae
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Atmospheric Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- Mycology (AREA)
- Dispersion Chemistry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/525,820 US5164308A (en) | 1990-05-21 | 1990-05-21 | Preparation of labelled triglyceride oils by cultivation of microorganisms |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE150793T1 true ATE150793T1 (de) | 1997-04-15 |
Family
ID=24094735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91911157T ATE150793T1 (de) | 1990-05-21 | 1991-05-13 | Markierte verbindungen zur verwendung in einem diagnostischen atemtest |
Country Status (7)
Country | Link |
---|---|
US (3) | US5164308A (de) |
EP (1) | EP0533775B1 (de) |
JP (1) | JPH05507275A (de) |
AT (1) | ATE150793T1 (de) |
CA (1) | CA2083041C (de) |
DE (1) | DE69125373T2 (de) |
WO (1) | WO1991018105A1 (de) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3354582B2 (ja) * | 1991-09-30 | 2002-12-09 | サントリー株式会社 | オメガ9系高度不飽和脂肪酸およびこれを含有する脂質の製造方法 |
US6569640B1 (en) * | 1993-03-12 | 2003-05-27 | Aphios Corporation | Method of fractionation of biologically-derived materials using critical fluids |
AU707748B2 (en) * | 1994-03-25 | 1999-07-22 | Isotechnika Inc. | Enhancement of the efficacy of drugs by deuteration |
US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
AU7731696A (en) * | 1995-11-15 | 1997-06-05 | Martek Corporation | Photosynthetic production of stable isotopically labeled recombinant proteins |
US5707602A (en) * | 1996-03-25 | 1998-01-13 | Meretek Diagnostics | Measurement of gastric emptying |
EP0904339B2 (de) * | 1996-05-15 | 2006-09-20 | DSM IP Assets B.V. | Verfahren zum extrahieren von sterol mit einem polaren lösungsmittel zur herstellung eines mikrobiellen öles mit niedrigem sterolgehalt |
US5785949A (en) * | 1996-09-05 | 1998-07-28 | Meretek Diagnostics | Measurement of liquid phase gastric emptying |
CA2249173C (en) * | 1997-10-06 | 2008-12-16 | Tokyo Gas Co., Ltd. | Diagnostic agent for liver function |
CA2250485C (en) * | 1997-10-21 | 2008-04-29 | Tokyo Gas Co., Ltd. | Diagnostic agent for diabetes |
US6284219B1 (en) | 1998-06-30 | 2001-09-04 | Phenome Sciences Inc. | In vivo determination of metabolic function for use in therapy management |
EP1006198A1 (de) * | 1998-12-01 | 2000-06-07 | Meretek Diagnostics | Ein nicht-invasives Verfahren zur funktionellen Feststellung von Säuglingen und Kindern mit einer ererbten metabolischen Störung |
US6291241B1 (en) * | 1999-03-29 | 2001-09-18 | Trevor Percival Castor | Methods for making Hypericum fractions and St. John's Wort products |
BR0110512A (pt) * | 2000-05-02 | 2004-03-09 | Otsuka Pharma Co Ltd | Preparação para medir a taxa de esvaziamento gástrico |
JP2004529363A (ja) * | 2001-06-05 | 2004-09-24 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア | 膵臓に基づく脂肪吸収不良障害を診断するための方法およびキット |
US20050281745A1 (en) * | 2002-03-22 | 2005-12-22 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Stable isotope based dynamic metabolic profiling of living organisms for characterization of metabolic diseases, drug testing and drug development |
JP4088097B2 (ja) * | 2002-04-26 | 2008-05-21 | サントリー株式会社 | 高度不飽和脂肪酸含有脂質の製造方法 |
WO2005015201A1 (en) * | 2003-08-06 | 2005-02-17 | Children's Hospital Medical Center | Use of non-absorbable fat in determining dietary fat absorption |
US20060188444A1 (en) * | 2005-02-23 | 2006-08-24 | Otsuka Pharmaceutical Co., Ltd. | Method for monitoring patient or subject compliance with medical prescriptions, and formulation for use in the method |
US20090041662A1 (en) * | 2005-02-23 | 2009-02-12 | Irie Yasuo | Method for Monitoring Patient or Subject Compliance with Medical Prescriptions, and Formulation for Use in the Method |
WO2006102342A2 (en) | 2005-03-18 | 2006-09-28 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
PL2447356T3 (pl) | 2005-06-07 | 2016-10-31 | Mikroorganizmy eukariotyczne do wytwarzania lipidów i przeciwutleniaczy | |
ES2371414T3 (es) | 2005-07-25 | 2012-01-02 | Otsuka Pharmaceutical Co., Ltd. | Preparación oral para medir la capacidad metabólica de la pirimidina. |
EP2043970B1 (de) * | 2006-07-05 | 2018-04-18 | Centre National De La Recherche Scientifique (C.N.R.S.) | Co-katalysiertes eisen-kupfer-verfahren für kohlenstoff-kohlenstoff- oder kohlenstoff-heteroatom-bindung |
CN101981201A (zh) | 2006-08-01 | 2011-02-23 | 加拿大海洋营养食品有限公司 | 产油微生物及改良这些微生物的方法 |
FR2904773B1 (fr) * | 2006-08-11 | 2008-11-07 | Lvmh Rech | Composition cosmetique amincissante contenant un extrait de biomasse de l'algue neochloris oleoabundans |
EP2078092A2 (de) | 2006-09-28 | 2009-07-15 | Microbia, Inc. | Herstellung von carotenoiden in öliger hefe und pilzen |
WO2008151149A2 (en) | 2007-06-01 | 2008-12-11 | Solazyme, Inc. | Production of oil in microorganisms |
RU2542374C2 (ru) * | 2008-04-09 | 2015-02-20 | Солазим, Инк. | Способ химической модификации липидов микроводорослей, способ получения мыла и мыло, включающее соли жирных кислот омыленных липидов микроводорослей |
US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
US8809037B2 (en) | 2008-10-24 | 2014-08-19 | Bioprocessh20 Llc | Systems, apparatuses and methods for treating wastewater |
ES2583639T3 (es) | 2008-11-28 | 2016-09-21 | Terravia Holdings, Inc. | Producción de aceites específicos en microorganismos heterótrofos |
US8709750B2 (en) * | 2008-12-15 | 2014-04-29 | Cavitation Technologies, Inc. | Method for processing an algae medium containing algae microorganisms to produce algal oil and by-products |
WO2011017171A1 (en) * | 2009-07-28 | 2011-02-10 | Joule Unlimited, Inc. | Photobioreactors, solar energy gathering systems, and thermal control methods |
WO2011088364A2 (en) * | 2010-01-15 | 2011-07-21 | Massachuseits Institute Of Technology | Bioprocess and microbe engineering for total carbon utilization in biofuelproduction |
JP5996527B2 (ja) | 2010-05-28 | 2016-09-21 | テラヴィア ホールディングス, インコーポレイテッド | 用途に応じた油を含む食品成分 |
SG10201509035WA (en) | 2010-11-03 | 2015-12-30 | Solazyme Inc | Microbial Oils With Lowered Pour Points, Dielectric Fluids Produced Therefrom, And Related Methods |
JP6071904B2 (ja) | 2011-02-02 | 2017-02-01 | テラヴィア ホールディングス, インコーポレイテッド | 組み換え油産生微生物から生成される用途に応じた油 |
BR112013028621A2 (pt) | 2011-05-06 | 2016-11-29 | Solazyme Inc | "microalgas oleaginosas recombinantes, método para produzir biomassa de microalga ou um produto produzido da biomassa, e método para produzir uma composição lipídica de microalga". |
JP2014185189A (ja) * | 2011-07-14 | 2014-10-02 | Ajinomoto Co Inc | 脂肪酸類の製造法 |
SG11201406711TA (en) | 2012-04-18 | 2014-11-27 | Solazyme Inc | Tailored oils |
CA2882528A1 (en) | 2012-08-20 | 2014-02-27 | Otsuka Pharmaceutical Co., Ltd. | Method for measuring carbohydrate metabolism ability, and composition for use in said method |
US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
CN105189740B (zh) | 2013-03-13 | 2019-01-15 | 帝斯曼营养品股份公司 | 工程化微生物 |
KR20210014204A (ko) | 2013-03-15 | 2021-02-08 | 오츠카 세이야쿠 가부시키가이샤 | 지방산 연소에 의한 인슐린 저항성의 측정 방법, 및 그에 사용하는 조성물 |
US9249252B2 (en) * | 2013-04-26 | 2016-02-02 | Solazyme, Inc. | Low polyunsaturated fatty acid oils and uses thereof |
FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
WO2015051319A2 (en) | 2013-10-04 | 2015-04-09 | Solazyme, Inc. | Tailored oils |
CN106574255A (zh) | 2014-07-10 | 2017-04-19 | 泰拉瑞亚控股公司 | 酮脂酰acp合酶基因及其用途 |
AR104042A1 (es) | 2015-03-26 | 2017-06-21 | Mara Renewables Corp | Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto |
KR102676949B1 (ko) | 2015-07-13 | 2024-06-19 | 마라 리뉴어블즈 코퍼레이션 | 크실로오스의 미세조류 대사를 강화시키는 방법 |
US10851395B2 (en) | 2016-06-10 | 2020-12-01 | MARA Renewables Corporation | Method of making lipids with improved cold flow properties |
US20240216321A1 (en) | 2022-12-02 | 2024-07-04 | Dsm Ip Assets B.V. | Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1342098A (en) * | 1971-03-12 | 1973-12-25 | Atomic Energy Authority Uk | 14c-labelled compounds |
US4485173A (en) * | 1981-01-19 | 1984-11-27 | Cpc International Inc. | Preparation of fats and oils |
JPS62146597A (ja) * | 1985-12-20 | 1987-06-30 | Idemitsu Petrochem Co Ltd | 菌体中の油脂成分の分離方法 |
JPH0763381B2 (ja) * | 1987-03-06 | 1995-07-12 | 財団法人相模中央化学研究所 | 微生物によるエイコサペンタエン酸含有脂質の製法 |
JPS63273484A (ja) * | 1987-04-30 | 1988-11-10 | Yoshihara Seiyu Kk | 高パルミトオレイン酸含有脂質の製造方法 |
JPS63295527A (ja) * | 1987-05-27 | 1988-12-01 | Nippon Oil & Fats Co Ltd | 高度不飽和脂肪酸の濃縮分離方法 |
GB8715428D0 (en) * | 1987-07-01 | 1987-08-26 | Univ Dundee | Organic compounds |
AU2122688A (en) * | 1987-07-20 | 1989-02-13 | Maricultura, Incorporated | Microorganism production of omega-3 (n-3) lipids |
JPH0225447A (ja) * | 1988-07-13 | 1990-01-26 | Nippon Oil & Fats Co Ltd | 高度不飽和脂肪酸類の製造方法 |
JPH02146597A (ja) * | 1988-11-28 | 1990-06-05 | Yamaha Corp | 電子楽器の楽音制御方法 |
JP2834251B2 (ja) * | 1990-01-22 | 1998-12-09 | 旭化成工業株式会社 | コンクリート板用吊込み治具 |
JPH03273484A (ja) * | 1990-03-23 | 1991-12-04 | Sanyo Electric Co Ltd | 自動販売機 |
-
1990
- 1990-05-21 US US07/525,820 patent/US5164308A/en not_active Expired - Fee Related
-
1991
- 1991-05-13 CA CA002083041A patent/CA2083041C/en not_active Expired - Fee Related
- 1991-05-13 EP EP91911157A patent/EP0533775B1/de not_active Expired - Lifetime
- 1991-05-13 AT AT91911157T patent/ATE150793T1/de not_active IP Right Cessation
- 1991-05-13 DE DE69125373T patent/DE69125373T2/de not_active Expired - Fee Related
- 1991-05-13 WO PCT/US1991/003335 patent/WO1991018105A1/en active IP Right Grant
- 1991-05-13 JP JP91510426A patent/JPH05507275A/ja active Pending
-
1992
- 1992-09-24 US US07/936,248 patent/US5376540A/en not_active Expired - Lifetime
-
1994
- 1994-11-10 US US08/338,755 patent/US5466434A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0533775B1 (de) | 1997-03-26 |
EP0533775A4 (en) | 1993-06-30 |
JPH05507275A (ja) | 1993-10-21 |
US5466434A (en) | 1995-11-14 |
WO1991018105A1 (en) | 1991-11-28 |
CA2083041C (en) | 2003-07-22 |
US5376540A (en) | 1994-12-27 |
CA2083041A1 (en) | 1991-11-22 |
US5164308A (en) | 1992-11-17 |
EP0533775A1 (de) | 1993-03-31 |
DE69125373T2 (de) | 1997-09-25 |
DE69125373D1 (de) | 1997-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |