ATE150013T1 - Vitamin d derivate - Google Patents

Vitamin d derivate

Info

Publication number
ATE150013T1
ATE150013T1 AT93912681T AT93912681T ATE150013T1 AT E150013 T1 ATE150013 T1 AT E150013T1 AT 93912681 T AT93912681 T AT 93912681T AT 93912681 T AT93912681 T AT 93912681T AT E150013 T1 ATE150013 T1 AT E150013T1
Authority
AT
Austria
Prior art keywords
pct
deuterium
sec
hydrogen
optionally substituted
Prior art date
Application number
AT93912681T
Other languages
English (en)
Inventor
Claus Aage Svensgaard Bretting
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Application granted granted Critical
Publication of ATE150013T1 publication Critical patent/ATE150013T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
AT93912681T 1992-07-03 1993-06-07 Vitamin d derivate ATE150013T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929214202A GB9214202D0 (en) 1992-07-03 1992-07-03 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE150013T1 true ATE150013T1 (de) 1997-03-15

Family

ID=10718182

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93912681T ATE150013T1 (de) 1992-07-03 1993-06-07 Vitamin d derivate

Country Status (17)

Country Link
US (1) US5545633A (de)
EP (1) EP0648207B1 (de)
JP (1) JPH08504746A (de)
KR (1) KR100285146B1 (de)
AT (1) ATE150013T1 (de)
AU (1) AU667378B2 (de)
CA (1) CA2131631A1 (de)
DE (1) DE69308852T2 (de)
DK (1) DK0648207T3 (de)
ES (1) ES2101319T3 (de)
FI (1) FI106120B (de)
GB (1) GB9214202D0 (de)
GR (1) GR3023407T3 (de)
HU (1) HU222775B1 (de)
NZ (1) NZ253026A (de)
RU (1) RU2114825C1 (de)
WO (1) WO1994001398A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226860D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Novel treatment
DE4427690A1 (de) * 1994-08-04 1996-02-08 Bogdahn Ulrich Prof Deuterium enthaltende pharmazeutische Zusammensetzung als Zytostatikum oder Tumor-Therapeutikum
DE69508895T2 (de) * 1994-12-14 1999-10-21 Duphar Int Res Vitamin-D-Derivate und Verfahren zur Herstellung dieser Verbindungen
TW422696B (en) 1995-03-20 2001-02-21 Katsuhiko Mukai Ophthalmic composition containing active vitamin D
GB9526208D0 (en) 1995-12-21 1996-02-21 Res Inst Medicine Chem Chemical compounds
GB9721156D0 (en) * 1997-10-06 1997-12-03 Leo Pharm Prod Ltd Novel vitamin d analogues
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
DK1714977T3 (da) 2001-10-19 2009-07-06 Isotechnika Inc Syntese af cyclosporinanaloger
US8404667B2 (en) * 2006-12-29 2013-03-26 Wisconsin Alumni Research Foundation Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
US20080293647A1 (en) 2004-11-12 2008-11-27 Luciano Adorini Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
US7241748B2 (en) * 2004-11-22 2007-07-10 Wisconsin Alumni Research Foundation 17,20(Z)-dehydro vitamin D analogs and their uses
US8193169B2 (en) * 2006-04-06 2012-06-05 Wisconsin Alumni Research Foundation (20R)-2α-methyl-19,26,2-trinor-vitamin D analogs
US7713953B2 (en) * 2008-07-10 2010-05-11 Wisconsin Alumni Research Foundation 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs
US8193170B2 (en) 2008-07-10 2012-06-05 Wisconsin Alumni Research Foundation 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs
US7893043B2 (en) 2008-07-10 2011-02-22 Wisconsin Alumni Research Foundation 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-vitamin D analogs
US7648974B1 (en) * 2008-07-10 2010-01-19 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 3,2-dihydrofuran ring
US8222236B2 (en) * 2008-07-10 2012-07-17 Wisconsin Alumni Research Foundation 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs
US8399439B2 (en) * 2008-07-10 2013-03-19 Wisconsin Alumni Research Foundation 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs
US7888339B2 (en) 2008-07-10 2011-02-15 Wisconsin Alumni Research Foundation 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs
US7879829B2 (en) * 2008-07-10 2011-02-01 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2-dihydrofuran ring
BRPI0916769A2 (pt) * 2008-07-15 2017-09-26 Theracos Inc derivados de benzilbenzeno deuterados e métodos de uso
KR20170096238A (ko) 2009-01-27 2017-08-23 베르그 엘엘씨 화학요법과 연관된 부작용을 경감시키기 위한 비타민 ｄ３ 및 이의 유사물
JP5978130B2 (ja) 2009-08-14 2016-08-24 バーグ エルエルシー 脱毛症を治療するためのビタミンｄ３およびその類似体
US8445468B2 (en) 2009-10-02 2013-05-21 Wisconsin Alumni Research Foundation (20S,22E)-2-methylene-19-nor-22-ene-1α,25-dihydroxyvitamin D3
US8217023B2 (en) 2009-10-02 2012-07-10 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2- or 3,2-cyclopentene ring
CA2837882C (en) 2011-06-03 2019-03-26 Wisconsin Alumni Research Foundation (22e)-2-methylene-26,27-cyclo-22-dehydro-1.alpha.-hydroxy-19-norvitamin d3 derivatives
WO2013003307A1 (en) 2011-06-28 2013-01-03 Wisconsin Alumni Research Foundation 2-methylene-(22e)-25-hexanoyl-24-oxo-26,27-cyclo-22-dehydro-19-nor-vitamin d analogs
US20130178449A1 (en) 2011-07-18 2013-07-11 Wisconsin Alumni Research Foundation 2-Methylene-20(21)-Dehydro-19,24,25,26,27-Pentanor-Vitamin D Analogs
US9416102B2 (en) 2013-01-23 2016-08-16 Wisconsin Alumni Research Foundation (22E)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D3 analogs
EP3003497B1 (de) 2013-05-29 2024-02-14 BPGbio, Inc. Verhinderung oder verringerung von chemotherapieinduzierter alopezie mit vitamin d
ES2714078T3 (es) 2014-11-25 2019-05-27 Trophea Dev Ab Tratamiento de atrofia de la piel con una combinación de ácido triyodotiroacético (TRIAC) y deshidroepiandrosterona (DHEA)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i

Also Published As

Publication number Publication date
RU94046411A (ru) 1996-10-10
KR100285146B1 (ko) 2001-04-02
EP0648207A1 (de) 1995-04-19
AU667378B2 (en) 1996-03-21
DE69308852T2 (de) 1997-11-27
RU2114825C1 (ru) 1998-07-10
FI950023A (fi) 1995-01-02
ES2101319T3 (es) 1997-07-01
HU222775B1 (hu) 2003-10-28
US5545633A (en) 1996-08-13
EP0648207B1 (de) 1997-03-12
GR3023407T3 (en) 1997-08-29
GB9214202D0 (en) 1992-08-12
DE69308852D1 (de) 1997-04-17
HUT68025A (en) 1995-05-29
CA2131631A1 (en) 1994-01-20
WO1994001398A1 (en) 1994-01-20
HU9402484D0 (en) 1994-11-28
DK0648207T3 (da) 1997-06-23
FI950023A0 (fi) 1995-01-02
FI106120B (fi) 2000-11-30
NZ253026A (en) 1997-07-27
JPH08504746A (ja) 1996-05-21
AU4311193A (en) 1994-01-31
KR950700876A (ko) 1995-02-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee