ATE149568T1 - Neues thrombininhibitorisches protein aus raubwanzen - Google Patents

Neues thrombininhibitorisches protein aus raubwanzen

Info

Publication number
ATE149568T1
ATE149568T1 AT92922434T AT92922434T ATE149568T1 AT E149568 T1 ATE149568 T1 AT E149568T1 AT 92922434 T AT92922434 T AT 92922434T AT 92922434 T AT92922434 T AT 92922434T AT E149568 T1 ATE149568 T1 AT E149568T1
Authority
AT
Austria
Prior art keywords
pct
bugs
predator
inhibitory protein
cys
Prior art date
Application number
AT92922434T
Other languages
English (en)
Inventor
Thomas Friedrich
Siegfried Bialojan
Burkhard Kroeger
Christoph Kuenast
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of ATE149568T1 publication Critical patent/ATE149568T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds
    • Y10S530/856—Snakes; venom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT92922434T 1991-11-06 1992-10-27 Neues thrombininhibitorisches protein aus raubwanzen ATE149568T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4136513A DE4136513A1 (de) 1991-11-06 1991-11-06 Neues thrombininhibitorisches protein aus raubwanzen

Publications (1)

Publication Number Publication Date
ATE149568T1 true ATE149568T1 (de) 1997-03-15

Family

ID=6444190

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92922434T ATE149568T1 (de) 1991-11-06 1992-10-27 Neues thrombininhibitorisches protein aus raubwanzen

Country Status (10)

Country Link
US (1) US5523287A (de)
EP (1) EP0612349B1 (de)
JP (1) JPH07500964A (de)
AT (1) ATE149568T1 (de)
CA (1) CA2121352A1 (de)
DE (2) DE4136513A1 (de)
DK (1) DK0612349T3 (de)
ES (1) ES2097931T3 (de)
MX (1) MX9206339A (de)
WO (1) WO1993009232A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19848785A1 (de) * 1998-10-22 2000-04-27 Max Planck Gesellschaft Gen für einen Thrombininhibitor aus Raubwanzen und Protein mit thrombinhemmender Wirkung
BR0009074A (pt) * 1999-03-18 2002-01-02 Merck Patent Gmbh Proteìna para bloquear adesão de plaqueta
MY128992A (en) 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
US7691839B2 (en) * 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1092421A (en) * 1964-02-28 1967-11-22 Nat Res Dev Improvements relating to anticoagulant materials
DE3819078A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie
US5019056A (en) * 1988-09-22 1991-05-28 Aegis Medical, Inc. Bowel care apparatus
DE3931839A1 (de) * 1989-09-23 1991-04-04 Basf Ag Neue proteine und ihre herstellung

Also Published As

Publication number Publication date
EP0612349B1 (de) 1997-03-05
MX9206339A (es) 1993-05-01
CA2121352A1 (en) 1993-05-13
WO1993009232A1 (de) 1993-05-13
JPH07500964A (ja) 1995-02-02
EP0612349A1 (de) 1994-08-31
DE59208142D1 (de) 1997-04-10
US5523287A (en) 1996-06-04
ES2097931T3 (es) 1997-04-16
DE4136513A1 (de) 1993-05-13
DK0612349T3 (da) 1997-07-28

Similar Documents

Publication Publication Date Title
DE69427650T2 (de) Verbindungen mit wachstumshormon-freisetzenden eigenschaften
DK0667910T3 (da) En Bacillus-promoter, afledt fra en variant af en alpha-amylase-promoter fra Bacillus licheniformis
ATE349892T1 (de) Schädlingsbekämpfungsmittel
NO941681D0 (no) Humane IL-4 mutant proteiner
DE69228749D1 (de) Neuartige polypeptide und ihre verwendung
ATE149568T1 (de) Neues thrombininhibitorisches protein aus raubwanzen
ATE213776T1 (de) (s)-hydroxynitrillyase aus hevea brasiliensis
DE69302375D1 (de) Kosmetische zusammensetzung zur erhaltung der frisur enthaltend ein milchprotein und/oder ein milchproteinhydrolysate und ein hydrolysate
RS49520B (sr) Antimikrobno aktivne smeše
DK0621899T3 (da) Ekspression af signalpeptidfrie stafylokinaser
ATE161046T1 (de) Neues thrombininhibitorisches protein aus zecken
DE69619530D1 (de) Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität
ATE146526T1 (de) Neues thrombininhibitorisches protein aus zecken
DK0667354T3 (da) Cytotoksisk faktor forbundet med dissemineret sklerose, dens detektion og kvantificering
ATE148744T1 (de) Neue thrombininhibitorische proteine aus landblutegeln
DE69836226D1 (de) Ifn rezeptor 1 bindende proteine, dafür kodierende dna und verfahren zur regulierung der zellulären antwort auf interferone
DE69416879T2 (de) Identifizierung, kwantifizierung und reinigung von insektiziden proteinen aus bacillus thuringiensis
HUP9601528A2 (hu) Véralvadásgátló hatású peptidszármazékok és a vegyületeket tartalmazó gyógyszerkészítmények

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee