DK0612349T3 - Nyt thrombininhiberende protein fra rovmider - Google Patents
Nyt thrombininhiberende protein fra rovmiderInfo
- Publication number
- DK0612349T3 DK0612349T3 DK92922434.3T DK92922434T DK0612349T3 DK 0612349 T3 DK0612349 T3 DK 0612349T3 DK 92922434 T DK92922434 T DK 92922434T DK 0612349 T3 DK0612349 T3 DK 0612349T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- inhibitory protein
- cys
- gly
- thrombin inhibitory
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 241000238876 Acari Species 0.000 title 1
- 108090000190 Thrombin Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 244000062645 predators Species 0.000 title 1
- 229960004072 thrombin Drugs 0.000 title 1
- 241001124072 Reduviidae Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
- Y10S530/856—Snakes; venom
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4136513A DE4136513A1 (de) | 1991-11-06 | 1991-11-06 | Neues thrombininhibitorisches protein aus raubwanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0612349T3 true DK0612349T3 (da) | 1997-07-28 |
Family
ID=6444190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92922434.3T DK0612349T3 (da) | 1991-11-06 | 1992-10-27 | Nyt thrombininhiberende protein fra rovmider |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5523287A (da) |
| EP (1) | EP0612349B1 (da) |
| JP (1) | JPH07500964A (da) |
| AT (1) | ATE149568T1 (da) |
| CA (1) | CA2121352A1 (da) |
| DE (2) | DE4136513A1 (da) |
| DK (1) | DK0612349T3 (da) |
| ES (1) | ES2097931T3 (da) |
| MX (1) | MX9206339A (da) |
| WO (1) | WO1993009232A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19848785A1 (de) * | 1998-10-22 | 2000-04-27 | Max Planck Gesellschaft | Gen für einen Thrombininhibitor aus Raubwanzen und Protein mit thrombinhemmender Wirkung |
| JP4805461B2 (ja) * | 1999-03-18 | 2011-11-02 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血小板接着の阻止用タンパク質 |
| MY128992A (en) | 2000-08-25 | 2007-03-30 | Merck Patent Gmbh | Saratin for inhibiting platelet adhesion to collagen |
| US7691839B2 (en) | 2005-09-28 | 2010-04-06 | Biovascular, Inc. | Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation |
| US20110034396A1 (en) * | 2005-09-28 | 2011-02-10 | Biovascular, Inc. | Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1092421A (en) * | 1964-02-28 | 1967-11-22 | Nat Res Dev | Improvements relating to anticoagulant materials |
| DE3819078A1 (de) * | 1988-06-04 | 1989-12-07 | Hoechst Ag | Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie |
| US5019056A (en) * | 1988-09-22 | 1991-05-28 | Aegis Medical, Inc. | Bowel care apparatus |
| DE3931839A1 (de) * | 1989-09-23 | 1991-04-04 | Basf Ag | Neue proteine und ihre herstellung |
-
1991
- 1991-11-06 DE DE4136513A patent/DE4136513A1/de not_active Withdrawn
-
1992
- 1992-10-27 WO PCT/EP1992/002450 patent/WO1993009232A1/de not_active Ceased
- 1992-10-27 CA CA002121352A patent/CA2121352A1/en not_active Abandoned
- 1992-10-27 AT AT92922434T patent/ATE149568T1/de not_active IP Right Cessation
- 1992-10-27 ES ES92922434T patent/ES2097931T3/es not_active Expired - Lifetime
- 1992-10-27 DE DE59208142T patent/DE59208142D1/de not_active Expired - Fee Related
- 1992-10-27 US US08/211,942 patent/US5523287A/en not_active Expired - Fee Related
- 1992-10-27 EP EP92922434A patent/EP0612349B1/de not_active Expired - Lifetime
- 1992-10-27 JP JP5508130A patent/JPH07500964A/ja active Pending
- 1992-10-27 DK DK92922434.3T patent/DK0612349T3/da active
- 1992-11-04 MX MX9206339A patent/MX9206339A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE149568T1 (de) | 1997-03-15 |
| US5523287A (en) | 1996-06-04 |
| MX9206339A (es) | 1993-05-01 |
| EP0612349A1 (de) | 1994-08-31 |
| WO1993009232A1 (de) | 1993-05-13 |
| ES2097931T3 (es) | 1997-04-16 |
| CA2121352A1 (en) | 1993-05-13 |
| DE59208142D1 (de) | 1997-04-10 |
| DE4136513A1 (de) | 1993-05-13 |
| JPH07500964A (ja) | 1995-02-02 |
| EP0612349B1 (de) | 1997-03-05 |
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