ATE149517T1 - Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung - Google Patents

Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung

Info

Publication number
ATE149517T1
ATE149517T1 AT91900187T AT91900187T ATE149517T1 AT E149517 T1 ATE149517 T1 AT E149517T1 AT 91900187 T AT91900187 T AT 91900187T AT 91900187 T AT91900187 T AT 91900187T AT E149517 T1 ATE149517 T1 AT E149517T1
Authority
AT
Austria
Prior art keywords
pct
pharmaceutical composition
composition containing
peptide derivative
production
Prior art date
Application number
AT91900187T
Other languages
English (en)
Inventor
Fred Widmer
Kailash Kumar Gauri
Stig Aasmul-Olsen
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Application granted granted Critical
Publication of ATE149517T1 publication Critical patent/ATE149517T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT91900187T 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung ATE149517T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat

Publications (1)

Publication Number Publication Date
ATE149517T1 true ATE149517T1 (de) 1997-03-15

Family

ID=8147734

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91900187T ATE149517T1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung

Country Status (12)

Country Link
US (1) US5411942A (de)
EP (1) EP0504207B1 (de)
JP (1) JPH05504336A (de)
KR (1) KR927003631A (de)
AT (1) ATE149517T1 (de)
CA (1) CA2069449A1 (de)
DE (1) DE69030100D1 (de)
DK (1) DK167813B1 (de)
FI (1) FI922620A (de)
HU (1) HUT61322A (de)
LV (1) LV10107B (de)
WO (1) WO1991009053A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
PL188795B1 (pl) * 1995-06-07 2005-04-29 Glaxo Group Ltd Związek wiążący się z receptorem trombopoetyny, kompozycja farmaceutyczna i zastosowanie związku wiążącego się z receptorem trombopoetyny
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
GB9818938D0 (en) 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
US8283315B2 (en) * 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
US8067367B2 (en) 2002-09-18 2011-11-29 Janssen Pharmaceutica, N.V. Methods of increasing platelet and hematopoietic stem cell production
US20040171554A1 (en) * 2003-02-07 2004-09-02 Genentech, Inc. Compositions and methods for enhancing apoptosis
US8076060B2 (en) * 2003-08-04 2011-12-13 Emil William Chynn Vaccination and immunotherapy as new therapeutic modalities in the treatment of glaucoma
HUE032370T2 (en) * 2003-08-28 2017-09-28 Janssen Pharmaceuticals Inc Peptides and compounds that bind to thrombopoietin receptors
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
WO2005094818A1 (en) * 2004-03-23 2005-10-13 Genentech, Inc. Azabicyclo-octane inhibitors of iap
SG152225A1 (en) 2004-04-07 2009-05-29 Novartis Ag Inhibitors of iap
US7244851B2 (en) * 2004-07-02 2007-07-17 Genentech, Inc. Inhibitors of IAP
US20060210542A1 (en) * 2004-08-16 2006-09-21 Yurkow Edward J Use of TPO mimetic compounds and pharmaceutical compositions in the treatment of anemia
DK1836201T4 (da) * 2004-12-20 2013-11-11 Genentech Inc Pyrrolidininhibitorer af IAP.
EP1973899A4 (de) * 2005-12-19 2010-10-20 Genentech Inc Hemmer von iap
PE20080951A1 (es) * 2006-08-02 2008-09-11 Novartis Ag DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
WO2008079735A1 (en) * 2006-12-19 2008-07-03 Genentech, Inc. Imidazopyridine inhibitors of iap
JP2010524467A (ja) * 2007-04-16 2010-07-22 モメンタ ファーマシューティカルズ インコーポレイテッド 規定の糖タンパク質産物および関連の方法
NZ580226A (en) * 2007-04-30 2012-11-30 Genentech Inc Dimer compounds as inhibitors of iap
KR20100110870A (ko) * 2008-01-11 2010-10-13 제넨테크, 인크. Iap의 억제제
CA2730448A1 (en) 2008-08-02 2010-02-11 Genentech, Inc. Inhibitors of iap
CN102124004A (zh) * 2008-08-16 2011-07-13 健泰科生物技术公司 Iap的氮杂吲哚抑制剂
MX2012011648A (es) 2010-04-07 2012-11-29 Momenta Pharmaceuticals Inc Glicanos de alta manosa.
US9170249B2 (en) 2011-03-12 2015-10-27 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing N-glycans in glycoprotein products
US9695244B2 (en) 2012-06-01 2017-07-04 Momenta Pharmaceuticals, Inc. Methods related to denosumab
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
US10464996B2 (en) 2013-05-13 2019-11-05 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
US20160257754A1 (en) 2013-10-16 2016-09-08 Momenta Pharmaceuticals Inc. Sialylated glycoproteins
EP4125994A4 (de) * 2020-03-25 2024-06-12 Aufbau Medical Innovations Limited Verfahren und mittel für glaukom

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457489A (en) * 1981-07-13 1984-07-03 Gilmore Samuel E Subsea fluid conduit connections for remote controlled valves
EP0088350B1 (de) * 1982-03-08 1985-02-20 Schering Corporation Carboxyalkyl-Dipeptiden, Verfahren zu deren Herstellung und deren pharmazeutische Zusammensetzungen
US4559340A (en) * 1983-11-25 1985-12-17 Schering Corporation Antihypertensive agents
US4634698A (en) * 1984-09-24 1987-01-06 Schering Corporation Antiglaucoma agents
AU583592B2 (en) * 1985-01-18 1989-05-04 Kailash Kumar Gauri Protein hydrolysates for pharmaceutical use
IL86386A0 (en) * 1987-05-21 1988-11-15 Merrell Dow Pharma Novel anf derivatives
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
GB8728560D0 (en) * 1987-12-07 1988-01-13 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
EP0504207B1 (de) 1997-03-05
HU9201883D0 (en) 1992-09-28
FI922620A0 (fi) 1992-06-05
DE69030100D1 (de) 1997-04-10
CA2069449A1 (en) 1991-06-08
AU636427B2 (en) 1993-04-29
JPH05504336A (ja) 1993-07-08
FI922620A (fi) 1992-06-05
DK167813B1 (da) 1993-12-20
EP0504207A1 (de) 1992-09-23
HUT61322A (en) 1992-12-28
WO1991009053A1 (en) 1991-06-27
LV10107B (en) 1995-02-20
AU6898991A (en) 1991-07-18
US5411942A (en) 1995-05-02
KR927003631A (ko) 1992-12-18
DK615889D0 (da) 1989-12-07
LV10107A (lv) 1994-05-10
DK615889A (da) 1991-06-08

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Legal Events

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