ATE148161T1 - Substrat für zellkulturen - Google Patents

Substrat für zellkulturen

Info

Publication number
ATE148161T1
ATE148161T1 AT92919901T AT92919901T ATE148161T1 AT E148161 T1 ATE148161 T1 AT E148161T1 AT 92919901 T AT92919901 T AT 92919901T AT 92919901 T AT92919901 T AT 92919901T AT E148161 T1 ATE148161 T1 AT E148161T1
Authority
AT
Austria
Prior art keywords
cells
cavities
lattice structure
substrate
cell cultures
Prior art date
Application number
AT92919901T
Other languages
German (de)
English (en)
Inventor
Karl Friedrich Weibezahn
Gudrun Knedlitschek
Hermann Dertinger
Klaus Schubert
Wilhelm Bier
Thomas Schaller
Original Assignee
Karlsruhe Forschzent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karlsruhe Forschzent filed Critical Karlsruhe Forschzent
Application granted granted Critical
Publication of ATE148161T1 publication Critical patent/ATE148161T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
    • C12N2535/10—Patterned coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT92919901T 1991-09-28 1992-09-23 Substrat für zellkulturen ATE148161T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4132379A DE4132379A1 (de) 1991-09-28 1991-09-28 Substrat fuer zellkulturen und kultur von zellen oder zellaggregaten

Publications (1)

Publication Number Publication Date
ATE148161T1 true ATE148161T1 (de) 1997-02-15

Family

ID=6441717

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92919901T ATE148161T1 (de) 1991-09-28 1992-09-23 Substrat für zellkulturen

Country Status (6)

Country Link
US (1) US5792653A (enExample)
EP (1) EP0605527B1 (enExample)
JP (1) JP2511247B2 (enExample)
AT (1) ATE148161T1 (enExample)
DE (2) DE4132379A1 (enExample)
WO (1) WO1993007258A1 (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0698085A4 (en) * 1994-03-11 1996-08-21 Baxter Int CONTINUOUS FLOW BIOREACTOR WITH CELL RETENTION GROOVES
DE4426315C1 (de) * 1994-07-25 1996-03-21 Gore W L & Ass Gmbh Membran zur Regeneration von Körpergeweben und Verwendung der Membran als Wundabdeckung und Hautersatz
DE19537033C2 (de) * 1995-02-16 1999-03-04 Forschungszentrum Juelich Gmbh Verfahren zur Bestimmung von Pharmakokinetik bzw. Toxikokinetik von Testsubstanzen mit Hilfe von in-vitro-Zellkultursystemen und dafür geeignete Vorrichtungen
GB9515327D0 (en) * 1995-07-26 1995-09-20 Univ London Site-directed bone formation
AU6828696A (en) * 1995-08-31 1997-03-19 Ashby Scientific Ltd Apparatus and methods for culturing biological material
GB9517717D0 (en) * 1995-08-31 1995-11-01 Ashby Scient Ltd Means for the growth of cells & micro-organisms
GB9613499D0 (en) * 1996-06-27 1996-08-28 Perkin Elmer Ltd Reflectance sampler
JP3878709B2 (ja) * 1997-03-31 2007-02-07 ミクロクローニング シーシーシーデー エイビー 生物試料を培養するための配列、その製法及びそれによる測定方法
CH692583A5 (de) 1998-03-03 2002-08-15 Weidmann H Ag Kulturgefäss.
EP1013756A1 (en) * 1998-12-21 2000-06-28 Corning Incorporated An apparatus used to hold and grow cells and allow their processes to grow and interconnect the individual cells and a method for making the apparatus
WO2000060053A1 (fr) * 1999-04-02 2000-10-12 Viktor Veniaminovich Tets Procede de production de recombinants de microbes (mutualisation ou procede de tets)
DE19952139C1 (de) * 1999-10-28 2000-12-21 Sibyll Weiner Transparenter Objektträger für die optische Mikroskopie
GB2357262B (en) * 1999-12-18 2003-11-12 Gardeners Digital Ltd Method and apparatus for sublimation printing of metal panels
JP4639558B2 (ja) * 2001-09-07 2011-02-23 株式会社島津製作所 マイクロウエルチップ
DE10210908A1 (de) * 2002-03-05 2003-12-04 Alfred Nordheim Vorrichtung zum Aufbringen von flüssigen Medien und Verfahren dazu
US8007744B2 (en) 2003-01-17 2011-08-30 Greiner Bio-One Gmbh Sample container for analyses
DE10321042B4 (de) * 2003-01-17 2006-09-21 Greiner Bio-One Gmbh Biochip-Träger
US9005549B2 (en) 2003-01-17 2015-04-14 Greiner Bio-One Gmbh High throughput polymer-based microarray slide
US20060240548A1 (en) * 2003-06-26 2006-10-26 Mordechai Deutsch Materials for constructing cell-chips, cell-chip covers, cell-chips coats, processed cell-chips and uses thereof
US9200245B2 (en) 2003-06-26 2015-12-01 Seng Enterprises Ltd. Multiwell plate
US8597597B2 (en) 2003-06-26 2013-12-03 Seng Enterprises Ltd. Picoliter well holding device and method of making the same
US7888110B2 (en) 2003-06-26 2011-02-15 Seng Enterprises Ltd. Pico liter well holding device and method of making the same
DE102004035267B3 (de) * 2004-07-21 2006-02-09 Forschungszentrum Karlsruhe Gmbh Formkörper, Verfahren zu seiner Herstellung und seine Verwendung
ES2352344T3 (es) 2005-01-25 2011-02-17 Seng Enterprises Limited Dispositivo de microfluido para estudio de células.
US8288120B2 (en) 2005-11-03 2012-10-16 Seng Enterprises Ltd. Method for studying floating, living cells
JP5039715B2 (ja) 2006-01-24 2012-10-03 ブラウン ユニバーシティ 細胞凝集及び封入デバイス及び方法
JP4159103B2 (ja) * 2006-02-21 2008-10-01 Ｓｃｉｖａｘ株式会社 細胞培養構造体、細胞培養容器、スフェロイド付き構造体、スフェロイド付き容器およびこれらの製造方法
US8980625B2 (en) * 2006-02-24 2015-03-17 National Food Research Institute Cell culture plate and method of manufacturing the same
DE102006011828A1 (de) 2006-03-13 2007-09-20 Gesellschaft für Schwerionenforschung mbH Bestrahlungsverifikationsvorrichtung für Strahlentherapieanlagen und Verfahren zur Handhabung derselben
WO2007138568A2 (en) * 2006-05-25 2007-12-06 Yeda Research And Development Co. Ltd. A device for microscopy flow-through experiments on non-adherent live cells
US8887938B2 (en) * 2006-07-06 2014-11-18 Pioneer Hi-Bred International, Inc. Buckling clamshell container for automated aliquot and dispersal processes
DE102007007718A1 (de) 2007-02-16 2008-08-21 Forschungszentrum Karlsruhe Gmbh Bioreaktor, Anordnung aus Bioreaktoren, Verfahren zu ihrer Herstellung und ihre Verwendung
DE102007028423A1 (de) * 2007-06-20 2008-12-24 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur Bildung von Aggregaten biologischer Zellen
US9145540B1 (en) 2007-11-15 2015-09-29 Seng Enterprises Ltd. Device for the study of living cells
WO2009081409A2 (en) 2007-12-26 2009-07-02 Seng Enterprises Ltd. Device for the study of living cells
DE102008017765A1 (de) 2008-04-03 2009-10-15 Technische Universität Ilmenau Mikrobioreaktor sowie CellChip-Mikrotiter-Platte
DE102008019691A1 (de) * 2008-04-15 2009-10-29 Technische Universität Ilmenau Teilaktives mikrofluidisches System für die 3D-Zellkultivierung sowie Verfahren zu dessen Perfusion
US9303245B2 (en) * 2008-06-20 2016-04-05 Universiteit Maastricht Self-assembling tissue modules
JP2012509663A (ja) * 2008-11-21 2012-04-26 コーニング インコーポレイテッド 細胞培養のための、突起間隔を開けた基板および装置
US20110004304A1 (en) * 2009-03-20 2011-01-06 Tao Sarah L Culturing retinal cells and tissues
US8501476B2 (en) 2009-10-07 2013-08-06 Brown University Assays and methods for fusing cell aggregates to form proto-tissues
US8481303B2 (en) 2009-10-12 2013-07-09 Corning Incorporated Microfluidic device for cell culture
DE102009046525B4 (de) * 2009-11-09 2012-04-26 Charité - Universitätsmedizin Berlin Verfahren und Kit zur Testung verschiedener, ausgewählter Werkstoffe und/oder Oberflächenstrukturen für die Kultur von Zellen
US20110159577A1 (en) * 2009-12-30 2011-06-30 E. I. Du Pont De Nemours And Company Divider for use with biolistic bombardment device
EP2759592A4 (en) * 2011-09-20 2015-04-29 Kuraray Co ADHÄSIONSZELLKULTURVERFAHREN
US9468680B2 (en) 2011-09-22 2016-10-18 Brown University Differential effects of drugs on transport in a multi-layer 3D spheroid model
US9243278B2 (en) 2011-09-22 2016-01-26 Brown University Mechanotransduction by the synergistic action of heterotypic cell interactions
DE102012103256A1 (de) 2012-04-16 2013-10-17 Karlsruher Institut für Technologie Mikrostrukturapparat mit optischer Oberflächengüte sowie Verfahren zur Herstellung desselben
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
JP2017532971A (ja) 2014-10-29 2017-11-09 コーニング インコーポレイテッド 細胞培養集合体を生成するためのマイクロウェル設計および製造
CN107109328B (zh) 2014-10-29 2021-02-05 康宁股份有限公司 细胞培养插入件
SG11201703500XA (en) 2014-10-29 2017-05-30 Corning Inc Perfusion bioreactor platform
WO2019014636A1 (en) 2017-07-14 2019-01-17 Corning Incorporated CONTAINER FOR CELL CULTURE
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
WO2019014635A1 (en) 2017-07-14 2019-01-17 Corning Incorporated 3D CELL CULTURE CONTAINERS FOR MANUAL OR AUTOMATIC EXCHANGE
EP3652292B1 (en) 2017-07-14 2025-06-18 Corning Incorporated Cell culture vessel for 3d culture and methods of culturing 3d cells
CN111051493B (zh) 2018-07-13 2023-11-03 康宁股份有限公司 具有稳定器装置的细胞培养容器
EP3649227A1 (en) 2018-07-13 2020-05-13 Corning Incorporated Fluidic devices including microplates with interconnected wells
CN111032851B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 具有包含液体介质传递表面的侧壁的微腔皿

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2902026C3 (de) * 1979-01-19 1981-10-29 Peters, J. Hinrich, Dr., 5064 Rösrath Biologisches Gefäß
FR2522014A1 (fr) * 1982-02-25 1983-08-26 Pasteur Institut Support pour cultures cellulaires, ensemble de culture comportant un tel support et procede pour cultiver des cellules en presence de ce support
CA1258436A (en) * 1984-08-01 1989-08-15 Michael A. Smoot Mat structure for use in filtration devices
DE3683321D1 (de) * 1985-06-18 1992-02-20 Anawa Muenchen Ag Biolog Lab Traeger fuer die kultivierung von menschlichen und/oder tierischen zellen in einem fermenter.
US5422270A (en) * 1987-05-19 1995-06-06 The United States Of America As Represented By The Department Of Health And Human Services One-step tray test for release of soluble mediators and apparatus therefore
US5108704A (en) * 1988-09-16 1992-04-28 W. R. Grace & Co.-Conn. Microfiltration apparatus with radially spaced nozzles
US5139946A (en) * 1988-11-02 1992-08-18 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion
DE3938632C1 (en) * 1989-11-21 1991-03-14 Adelbert Prof. Dr.Dr. 8046 Garching De Bacher Culturing living animal cells - using natural or synthetic polymer substrate vacuum deposition coated with e.g. nitride of Gp=III element
US5554536A (en) * 1995-01-05 1996-09-10 Millipore Investment Holdings Limited Biological analysis device having improved contamination prevention

Also Published As

Publication number Publication date
US5792653A (en) 1998-08-11
JP2511247B2 (ja) 1996-06-26
DE4132379C2 (enExample) 1993-07-15
WO1993007258A1 (de) 1993-04-15
EP0605527B1 (de) 1997-01-22
EP0605527A1 (de) 1994-07-13
DE4132379A1 (de) 1993-04-08
JPH06507076A (ja) 1994-08-11
DE59207961D1 (de) 1997-03-06

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