ATE144532T1 - Verfahren zur herstellung von s-acylderivaten des glutathion, und damit hergestellte verbindungen - Google Patents
Verfahren zur herstellung von s-acylderivaten des glutathion, und damit hergestellte verbindungenInfo
- Publication number
- ATE144532T1 ATE144532T1 AT91912027T AT91912027T ATE144532T1 AT E144532 T1 ATE144532 T1 AT E144532T1 AT 91912027 T AT91912027 T AT 91912027T AT 91912027 T AT91912027 T AT 91912027T AT E144532 T1 ATE144532 T1 AT E144532T1
- Authority
- AT
- Austria
- Prior art keywords
- glutathione
- producing
- produced therefrom
- compounds produced
- acyl derivatives
- Prior art date
Links
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical class OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 108010024636 Glutathione Proteins 0.000 abstract 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- 229960003180 glutathione Drugs 0.000 abstract 2
- 150000001263 acyl chlorides Chemical class 0.000 abstract 1
- 150000001244 carboxylic acid anhydrides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02076090A IT1248994B (it) | 1990-06-26 | 1990-06-26 | Processo per la preparazione di s-acil derivati di glutatione composti ottenuti da detto processo e intermedio utile per la loro preparazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE144532T1 true ATE144532T1 (de) | 1996-11-15 |
Family
ID=11171663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91912027T ATE144532T1 (de) | 1990-06-26 | 1991-06-21 | Verfahren zur herstellung von s-acylderivaten des glutathion, und damit hergestellte verbindungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5382679A (OSRAM) |
| EP (1) | EP0536231B1 (OSRAM) |
| JP (1) | JPH05508405A (OSRAM) |
| AT (1) | ATE144532T1 (OSRAM) |
| AU (1) | AU8073691A (OSRAM) |
| CA (1) | CA2086107A1 (OSRAM) |
| DE (1) | DE69122867T2 (OSRAM) |
| ES (1) | ES2095940T3 (OSRAM) |
| IT (1) | IT1248994B (OSRAM) |
| WO (1) | WO1992000320A1 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5679643A (en) * | 1987-10-13 | 1997-10-21 | Terrapin Technologies, Inc. | Glutathione analogs and paralog panels comprising glutathione mimics |
| US5599903A (en) * | 1992-04-03 | 1997-02-04 | Terrapin Technologies, Inc. | Glutathione analogs and paralog panels comprising glutathione mimics |
| US5786336A (en) * | 1991-04-29 | 1998-07-28 | Terrapin Technologies, Inc. | Target-selective protocols based on mimics |
| US5955432A (en) * | 1992-04-03 | 1999-09-21 | Terrapin Technologies, Inc. | Metabolic effects of certain glutathione analogs |
| US5624955A (en) * | 1995-05-03 | 1997-04-29 | Regents Of The University Of Minnesota | Compounds that enhance the concentration of glutathione in tissues |
| US20040229815A1 (en) * | 2003-01-03 | 2004-11-18 | Nagasawa Herbert T. | Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug |
| DE602004009764T2 (de) * | 2003-02-21 | 2008-08-28 | Metabolix, Inc., Cambridge | Pha-klebstoffe |
| US7781539B2 (en) * | 2003-02-21 | 2010-08-24 | Metabolix Inc. | PHA blends |
| US7718720B2 (en) * | 2003-12-30 | 2010-05-18 | Metabolix Inc. | Nucleating agents |
| EP1874948B1 (en) | 2005-03-31 | 2013-03-20 | NewSouth Innovations Pty Limited | Process for the production of y-glutamylcysteine |
| ITFI20070224A1 (it) * | 2007-10-12 | 2009-04-13 | Univ Firenze | Nuovi derivati s-acilici del glutatione, loro sintesi e uso nel trattamento di patologie correlate allo stress ossidativo cellulare |
| JP5267096B2 (ja) * | 2008-12-12 | 2013-08-21 | 住友化学株式会社 | Ｎ，Ｓ−ジ−ｔｅｒｔ−ブトキシカルボニルグルタチオン蛍光誘導体及びそれを中間体として用いるグルタチオン蛍光誘導体の製造方法 |
| US20110160144A1 (en) * | 2009-12-28 | 2011-06-30 | Perricone Nicholas V | Topical Acyl Glutathione Formulations |
| US8580742B2 (en) | 2010-03-05 | 2013-11-12 | N.V. Perricone Llc | Topical glutathione formulations for menopausal skin |
| US8609604B2 (en) | 2009-12-28 | 2013-12-17 | N.V. Perricone Llc | Methods of improving the appearance of aging skin |
| US20110160143A1 (en) * | 2009-12-28 | 2011-06-30 | Perricone Nicholas V | Topical Acyl Glutathione Psoriasis Compositions |
| US9475930B2 (en) | 2012-08-17 | 2016-10-25 | Metabolix, Inc. | Biobased rubber modifiers for polymer blends |
| US10669417B2 (en) | 2013-05-30 | 2020-06-02 | Cj Cheiljedang Corporation | Recyclate blends |
| ITMI20131856A1 (it) * | 2013-11-08 | 2015-05-09 | Gnosis Spa | Processo per la preparazione di differenti forme cristalline del s-acetil glutatione e loro utilizzi in formulazioni farmaceutiche e nutraceutiche |
| CN106459544B (zh) | 2014-03-27 | 2021-10-01 | Cj 第一制糖株式会社 | 高度填充的聚合物体系 |
| CN104072577A (zh) * | 2014-07-01 | 2014-10-01 | 田州益膳（北京）食品有限公司 | S-乙酰-l-谷胱甘肽的制备方法 |
| CN104151396B (zh) * | 2014-08-11 | 2017-12-26 | 济南大学 | 混合溶剂中催化合成s‑乙酰基‑l‑谷胱甘肽的方法 |
| IT202200021528A1 (it) | 2022-10-19 | 2024-04-19 | Dr Tezza S R L | Procedimento per la preparazione di derivati del glutatione e della cisteina |
-
1990
- 1990-06-26 IT IT02076090A patent/IT1248994B/it active IP Right Grant
-
1991
- 1991-06-21 EP EP91912027A patent/EP0536231B1/en not_active Expired - Lifetime
- 1991-06-21 WO PCT/EP1991/001154 patent/WO1992000320A1/en not_active Ceased
- 1991-06-21 AT AT91912027T patent/ATE144532T1/de not_active IP Right Cessation
- 1991-06-21 AU AU80736/91A patent/AU8073691A/en not_active Abandoned
- 1991-06-21 DE DE69122867T patent/DE69122867T2/de not_active Expired - Fee Related
- 1991-06-21 CA CA002086107A patent/CA2086107A1/en not_active Abandoned
- 1991-06-21 ES ES91912027T patent/ES2095940T3/es not_active Expired - Lifetime
- 1991-06-21 JP JP3511061A patent/JPH05508405A/ja active Pending
-
1993
- 1993-02-10 US US07/958,344 patent/US5382679A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU8073691A (en) | 1992-01-23 |
| IT1248994B (it) | 1995-02-11 |
| JPH05508405A (ja) | 1993-11-25 |
| EP0536231B1 (en) | 1996-10-23 |
| IT9020760A0 (OSRAM) | 1990-06-26 |
| IT9020760A1 (it) | 1991-12-26 |
| EP0536231A1 (en) | 1993-04-14 |
| ES2095940T3 (es) | 1997-03-01 |
| DE69122867D1 (de) | 1996-11-28 |
| WO1992000320A1 (en) | 1992-01-09 |
| CA2086107A1 (en) | 1991-12-27 |
| DE69122867T2 (de) | 1997-03-06 |
| US5382679A (en) | 1995-01-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE144532T1 (de) | Verfahren zur herstellung von s-acylderivaten des glutathion, und damit hergestellte verbindungen | |
| ATE121088T1 (de) | Verfahren zur herstellung von imidazo(4,5- c>chinolin-4-aminen. | |
| ATE241012T1 (de) | Verfahren zur herstellung von humanen relaxin | |
| ATE101116T1 (de) | Gabapentinmonohydrat und verfahren zu dessen herstellung. | |
| DE69316405D1 (de) | Verfahren zur fermentativen Herstellung von Aminosäuren | |
| DE69033600D1 (de) | Verfahren zur Isolierung von Haemopnilus influenzae Protein-E | |
| DE68919246D1 (de) | Verfahren zur Herstellung von Aminosäuren. | |
| DE69104226D1 (de) | Vorrichtung und verfahren zur behandlung von salzen mittels elektrodialyse zur herstellung von säuren und/oder basen hoher reinheit. | |
| DE59609239D1 (de) | Verfahren zur abtrennung von mittelsiedern aus einem gemisch aus leicht-, mittel- und hochsiedern | |
| ATE317912T1 (de) | Verfahren zur herstellung von beta-lactamen | |
| DE69329500D1 (de) | Ein verfahren zur herstellung von immunosuppressiva und eine neuartige mikrobielle spezies, die dabei eingesetzt wird | |
| DE68909627D1 (de) | Verfahren zur Herstellung von Aktivkohle. | |
| DE69011880D1 (de) | Verfahren zur Herstellung von L-Aminosäuren durch Fermentation. | |
| DE69023529D1 (de) | Verfahren zur Behandlung von wässerigen Fermentationsbrühen. | |
| ATE153073T1 (de) | Verfahren zur herstellung von n- acetylneuraminsäure | |
| DE68927103D1 (de) | Verfahren zur herstellung von gamma- und delta-lactonen | |
| HU9300501D0 (en) | Method for producing new derivatives of beta-amino acids | |
| DE68901300D1 (de) | Verfahren zur herstellung von ferrichlorid aus ferrochlorid. | |
| DE69102294D1 (de) | Verfahren zur Behandlung von Abgasen, die ClF3 enthalten. | |
| ATE116636T1 (de) | Verfahren zur herstellung von 2,6- dichlordiphenylaminessigsäurederivaten. | |
| ATE167871T1 (de) | Verfahren zur herstellung von vancomycin | |
| DE68923312D1 (de) | Verfahren zur Herstellung von Caprolactam mit hoher Reinheit. | |
| ATE219052T1 (de) | Verfahren zur herstellung von 2-acetylthio-3- phenyl-propionsäure und deren salzen | |
| DE68927649D1 (de) | Verfahren zur Herstellung von 3',4'-Anhydrovinblastin | |
| DE69903109D1 (de) | Verfahren zur Reinigung von Roxithromycin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |