ES2095940T3 - Procedimiento para la preparacion de derivados de s-acil-glutation y compuestos obtenidos por dicho procedimiento. - Google Patents

Procedimiento para la preparacion de derivados de s-acil-glutation y compuestos obtenidos por dicho procedimiento.

Info

Publication number
ES2095940T3
ES2095940T3 ES91912027T ES91912027T ES2095940T3 ES 2095940 T3 ES2095940 T3 ES 2095940T3 ES 91912027 T ES91912027 T ES 91912027T ES 91912027 T ES91912027 T ES 91912027T ES 2095940 T3 ES2095940 T3 ES 2095940T3
Authority
ES
Spain
Prior art keywords
procedure
acil
preparation
glutation
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91912027T
Other languages
English (en)
Inventor
Lauro Galzigna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics SpA
Original Assignee
Boehringer Mannheim Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Italia SpA filed Critical Boehringer Mannheim Italia SpA
Application granted granted Critical
Publication of ES2095940T3 publication Critical patent/ES2095940T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE PRESENTA UN PROCESO SELECTIVO Y DE ALTO RENDIMIENTO PARA LA PREPARACION DE GLUTATIONA S-ACILATANTE, QUE COMPRENDE LA REACCION ENTRE GLUTATIONA Y UN CLORURO DE ACIL O UN ANHIDRIDO DE UN ACIDO CARBOXILICO EN ACIDO TRIFLUOROACETICO.
ES91912027T 1990-06-26 1991-06-21 Procedimiento para la preparacion de derivados de s-acil-glutation y compuestos obtenidos por dicho procedimiento. Expired - Lifetime ES2095940T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02076090A IT1248994B (it) 1990-06-26 1990-06-26 Processo per la preparazione di s-acil derivati di glutatione composti ottenuti da detto processo e intermedio utile per la loro preparazione

Publications (1)

Publication Number Publication Date
ES2095940T3 true ES2095940T3 (es) 1997-03-01

Family

ID=11171663

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912027T Expired - Lifetime ES2095940T3 (es) 1990-06-26 1991-06-21 Procedimiento para la preparacion de derivados de s-acil-glutation y compuestos obtenidos por dicho procedimiento.

Country Status (10)

Country Link
US (1) US5382679A (es)
EP (1) EP0536231B1 (es)
JP (1) JPH05508405A (es)
AT (1) ATE144532T1 (es)
AU (1) AU8073691A (es)
CA (1) CA2086107A1 (es)
DE (1) DE69122867T2 (es)
ES (1) ES2095940T3 (es)
IT (1) IT1248994B (es)
WO (1) WO1992000320A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599903A (en) * 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5679643A (en) * 1987-10-13 1997-10-21 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5955432A (en) * 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
US5624955A (en) * 1995-05-03 1997-04-29 Regents Of The University Of Minnesota Compounds that enhance the concentration of glutathione in tissues
US20040229815A1 (en) 2003-01-03 2004-11-18 Nagasawa Herbert T. Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug
US7781539B2 (en) * 2003-02-21 2010-08-24 Metabolix Inc. PHA blends
EP1935945A1 (en) * 2003-02-21 2008-06-25 Metabolix, Inc. PHA Blends
WO2005066256A1 (en) * 2003-12-30 2005-07-21 Metabolix, Inc. Nucleating agents
JP5221336B2 (ja) 2005-03-31 2013-06-26 ニューサウス イノベイションズ ピーティーワイ リミテッド γ−グルタミルシステインの製造プロセス
ITFI20070224A1 (it) * 2007-10-12 2009-04-13 Univ Firenze Nuovi derivati s-acilici del glutatione, loro sintesi e uso nel trattamento di patologie correlate allo stress ossidativo cellulare
JP5267096B2 (ja) * 2008-12-12 2013-08-21 住友化学株式会社 Ｎ，Ｓ−ジ−ｔｅｒｔ−ブトキシカルボニルグルタチオン蛍光誘導体及びそれを中間体として用いるグルタチオン蛍光誘導体の製造方法
US20110160143A1 (en) * 2009-12-28 2011-06-30 Perricone Nicholas V Topical Acyl Glutathione Psoriasis Compositions
US20110160144A1 (en) * 2009-12-28 2011-06-30 Perricone Nicholas V Topical Acyl Glutathione Formulations
US8580742B2 (en) * 2010-03-05 2013-11-12 N.V. Perricone Llc Topical glutathione formulations for menopausal skin
US8609604B2 (en) 2009-12-28 2013-12-17 N.V. Perricone Llc Methods of improving the appearance of aging skin
US9475930B2 (en) 2012-08-17 2016-10-25 Metabolix, Inc. Biobased rubber modifiers for polymer blends
EP3004225A1 (en) 2013-05-30 2016-04-13 Metabolix, Inc. Recyclate blends
ITMI20131856A1 (it) * 2013-11-08 2015-05-09 Gnosis Spa Processo per la preparazione di differenti forme cristalline del s-acetil glutatione e loro utilizzi in formulazioni farmaceutiche e nutraceutiche
US10611903B2 (en) 2014-03-27 2020-04-07 Cj Cheiljedang Corporation Highly filled polymer systems
CN104072577A (zh) * 2014-07-01 2014-10-01 田州益膳（北京）食品有限公司 S-乙酰-l-谷胱甘肽的制备方法
CN104151396B (zh) * 2014-08-11 2017-12-26 济南大学 混合溶剂中催化合成s‑乙酰基‑l‑谷胱甘肽的方法

Also Published As

Publication number Publication date
CA2086107A1 (en) 1991-12-27
EP0536231B1 (en) 1996-10-23
US5382679A (en) 1995-01-17
WO1992000320A1 (en) 1992-01-09
EP0536231A1 (en) 1993-04-14
ATE144532T1 (de) 1996-11-15
IT9020760A1 (it) 1991-12-26
IT9020760A0 (es) 1990-06-26
JPH05508405A (ja) 1993-11-25
DE69122867D1 (de) 1996-11-28
DE69122867T2 (de) 1997-03-06
AU8073691A (en) 1992-01-23
IT1248994B (it) 1995-02-11

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