ATE136552T1 - Reinigung von menschlichem, aus einer escherichia coli mutante abgesonderten interleukin 4 - Google Patents

Reinigung von menschlichem, aus einer escherichia coli mutante abgesonderten interleukin 4

Info

Publication number
ATE136552T1
ATE136552T1 AT91903451T AT91903451T ATE136552T1 AT E136552 T1 ATE136552 T1 AT E136552T1 AT 91903451 T AT91903451 T AT 91903451T AT 91903451 T AT91903451 T AT 91903451T AT E136552 T1 ATE136552 T1 AT E136552T1
Authority
AT
Austria
Prior art keywords
secreted
sodium chloride
coli mutant
purification
escherichia coli
Prior art date
Application number
AT91903451T
Other languages
English (en)
Inventor
John Chu-Tay Tang
David Naveh
T L Nagabhushan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE136552T1 publication Critical patent/ATE136552T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5406IL-4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT91903451T 1990-05-31 1991-01-04 Reinigung von menschlichem, aus einer escherichia coli mutante abgesonderten interleukin 4 ATE136552T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/531,270 US5077388A (en) 1990-05-31 1990-05-31 Purification of human interleukin-4 from a secreted escherichia coli mutant

Publications (1)

Publication Number Publication Date
ATE136552T1 true ATE136552T1 (de) 1996-04-15

Family

ID=24116964

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91903451T ATE136552T1 (de) 1990-05-31 1991-01-04 Reinigung von menschlichem, aus einer escherichia coli mutante abgesonderten interleukin 4

Country Status (16)

Country Link
US (1) US5077388A (de)
EP (1) EP0537148B1 (de)
JP (1) JP2573767B2 (de)
AT (1) ATE136552T1 (de)
AU (1) AU659993B2 (de)
CA (1) CA2084186C (de)
DE (1) DE69118696T2 (de)
DK (1) DK0537148T3 (de)
ES (1) ES2085986T3 (de)
GR (1) GR3019705T3 (de)
IE (1) IE73668B1 (de)
IL (1) IL96880A0 (de)
MY (1) MY130013A (de)
NZ (1) NZ236699A (de)
WO (1) WO1991018919A1 (de)
ZA (1) ZA9193B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100191223B1 (ko) * 1989-07-28 1999-06-15 둘락 노먼 씨. 인터루킨-4의 정제방법 및 이를 함유하는 약제학적 조성물
US5840851A (en) * 1993-07-23 1998-11-24 Plomer; J. Jeffrey Purification of hemoglobin
KR0141651B1 (ko) * 1994-09-07 1998-06-15 강재헌 금속이온 친화성 크로마토그라피를 이용한 히루딘의 정제방법
US6171856B1 (en) 1997-07-30 2001-01-09 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
WO1999006059A2 (en) * 1997-07-30 1999-02-11 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
EP3088412B1 (de) * 2001-03-09 2021-05-05 Chugai Seiyaku Kabushiki Kaisha Proteinaufreinigungsverfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80678A (en) * 1985-11-19 1999-05-09 Schering Biotech Corp Human interleukin-4
JPH04506339A (ja) * 1988-12-21 1992-11-05 シェリング・コーポレーション 血中コレステロール値低下のためのインターロイキン―4の使用
KR100191223B1 (ko) * 1989-07-28 1999-06-15 둘락 노먼 씨. 인터루킨-4의 정제방법 및 이를 함유하는 약제학적 조성물

Also Published As

Publication number Publication date
GR3019705T3 (en) 1996-07-31
IE910027A1 (en) 1991-12-04
CA2084186A1 (en) 1991-12-01
DK0537148T3 (da) 1996-05-06
JP2573767B2 (ja) 1997-01-22
ZA9193B (en) 1991-09-25
EP0537148B1 (de) 1996-04-10
MY130013A (en) 2007-05-31
JPH05505934A (ja) 1993-09-02
ES2085986T3 (es) 1996-06-16
IL96880A0 (en) 1992-03-29
DE69118696T2 (de) 1996-08-29
AU7222091A (en) 1991-12-31
WO1991018919A1 (en) 1991-12-12
IE73668B1 (en) 1997-07-02
CA2084186C (en) 1999-12-14
NZ236699A (en) 1992-08-26
DE69118696D1 (de) 1996-05-15
US5077388A (en) 1991-12-31
AU659993B2 (en) 1995-06-08
EP0537148A1 (de) 1993-04-21

Similar Documents

Publication Publication Date Title
AU569129B2 (en) Factor viii:c purification
MY103892A (en) Interleukin-2 of high purity production and use
BE892846A (fr) Procede de purification de substance physiologiquement active a activite antitumorale, et substance ainsi obtenue
SE8005498L (sv) Homogent fibroblastinterferon och framstellning derav
GB1534812A (en) Method for the purification of interferon
ATE136552T1 (de) Reinigung von menschlichem, aus einer escherichia coli mutante abgesonderten interleukin 4
Dinarello et al. Studies on the active site of human leukocytic pyrogen
DE69027995D1 (de) Reinigungsverfahren von transformierendem wachstumsfaktor (tgf)
EP0152346A3 (en) Method for purifying gamma-interferon
AU1239495A (en) An electrophoretic method to assess human cerebrospinal fluid
EP0446850B1 (de) Verfahren zur Herstellung von rekombinantem Humaninterferon-beta in reiner Form
FR2509139B1 (fr) Isolement de proteine microbienne d'une teneur reduite en acides nucleiques
FR2547814B1 (fr) Derives de l'acide bicyclo (3.2.1.) octane carboxylique, leur procede de preparation et leur application therapeutique
Yoshimoto et al. Affinity chromatographic purification of human lysozyme, with special reference to human leukemia lysozyme
JPS5599191A (en) Purification of kallikrein in human urine
Yamamoto et al. Purification of fish gastric hyaluronidase
RU1839190C (ru) Способ очистки микробной эстеразы
KR920012436A (ko) 인간 인슐린 유사 성장인자-i의 정제 방법
RU96102282A (ru) Способ терапии поллиноза
ES8304150A1 (es) "un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral".
Varghese et al. Hemolysin of Myxococcus fulvus NK 35: I. Production and Isolation
JPS61181395A (ja) マウスインタ−フエロンの精製法
SU1706211A1 (ru) Способ выделения цитохрома c из биомассы дрожжей
SU1538513A1 (ru) Способ выделения соматотропина человека
KR910018547A (ko) 형질 전환된 대장균으로 부터 사람 인터페론 -β를 정제하는 방법

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee