ATE23540T1 - Verfahren zur reinigung einer physiologisch aktiven substanz mit antitumor aktivitaet. - Google Patents
Verfahren zur reinigung einer physiologisch aktiven substanz mit antitumor aktivitaet.Info
- Publication number
- ATE23540T1 ATE23540T1 AT82301853T AT82301853T ATE23540T1 AT E23540 T1 ATE23540 T1 AT E23540T1 AT 82301853 T AT82301853 T AT 82301853T AT 82301853 T AT82301853 T AT 82301853T AT E23540 T1 ATE23540 T1 AT E23540T1
- Authority
- AT
- Austria
- Prior art keywords
- active substance
- physiologically active
- substance
- purification
- gel filtration
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56209840A JPS57140725A (en) | 1981-12-28 | 1981-12-28 | Physiologically active substance having carcinostatic action |
EP82301853A EP0090892B1 (de) | 1981-12-28 | 1982-04-07 | Verfahren zur Reinigung einer physiologisch aktiven Substanz mit Antitumor Aktivität |
FR8206351A FR2524891B1 (fr) | 1981-12-28 | 1982-04-13 | Procede pour purifier une substance proteinee douee d'activite antitumorale |
BE0/207819A BE892846A (fr) | 1981-12-28 | 1982-04-14 | Procede de purification de substance physiologiquement active a activite antitumorale, et substance ainsi obtenue |
CA000405748A CA1199579A (en) | 1981-12-28 | 1982-06-22 | Process for the purification of physiologically active substance having antitumor activity |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE23540T1 true ATE23540T1 (de) | 1986-11-15 |
Family
ID=27507588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT82301853T ATE23540T1 (de) | 1981-12-28 | 1982-04-07 | Verfahren zur reinigung einer physiologisch aktiven substanz mit antitumor aktivitaet. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0090892B1 (de) |
JP (1) | JPS57140725A (de) |
AT (1) | ATE23540T1 (de) |
BE (1) | BE892846A (de) |
CA (1) | CA1199579A (de) |
FR (1) | FR2524891B1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57140725A (en) * | 1981-12-28 | 1982-08-31 | Dainippon Pharmaceut Co Ltd | Physiologically active substance having carcinostatic action |
US4920196A (en) * | 1982-07-30 | 1990-04-24 | Genentech, Inc. | Human lymphotoxin |
WO1984001288A1 (en) * | 1982-10-06 | 1984-04-12 | Takeshi Makitsubo | Process for extracting tumor necrosis factor from macrophage |
JPS59118716A (ja) * | 1982-12-24 | 1984-07-09 | Otsuka Pharmaceut Co Ltd | 制ガン作用を有する低分子蛋白質 |
JPS6019719A (ja) | 1983-07-15 | 1985-01-31 | Asahi Chem Ind Co Ltd | 抗腫瘍活性を有する蛋白質 |
GB8330969D0 (en) * | 1983-11-21 | 1983-12-29 | Wellcome Found | Promoting healing |
JPH0695939B2 (ja) * | 1983-12-02 | 1994-11-30 | 大日本製薬株式会社 | ウサギ癌壊死因子をコ−ドするクロ−ン化dνa |
US4879226A (en) * | 1984-04-06 | 1989-11-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel human physiologically active polypeptide |
US6686455B1 (en) | 1984-07-05 | 2004-02-03 | Genentech, Inc. | Tumor necrosis factor |
US5672347A (en) * | 1984-07-05 | 1997-09-30 | Genentech, Inc. | Tumor necrosis factor antagonists and their use |
GB2161813B (en) * | 1984-07-20 | 1988-07-13 | Michiko Koga | Anti-tumor agent |
EP0178050A1 (de) * | 1984-08-13 | 1986-04-16 | The Wellcome Foundation Limited | Eiweisssubstanz |
JPS6163698A (ja) * | 1984-09-05 | 1986-04-01 | Asahi Chem Ind Co Ltd | 生理活性物質に対するモノクロ−ナル抗体とそれを用いる生理活性物質の精製方法 |
US4777242A (en) * | 1986-10-10 | 1988-10-11 | Phillips Petroleum Company | Purification of recombinant tumor necrosis factor |
JPH0688906B2 (ja) * | 1988-08-10 | 1994-11-09 | 株式会社生体調節研究所 | 制癌作用を有する生物活性物質の製造方法およびそれにより得られる制癌作用を有する生物活性物質 |
KR970005042B1 (ko) * | 1993-02-09 | 1997-04-11 | 한일합성섬유공업 주식회사 | 종양괴사인자-알파 뮤테인 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57140725A (en) * | 1981-12-28 | 1982-08-31 | Dainippon Pharmaceut Co Ltd | Physiologically active substance having carcinostatic action |
-
1981
- 1981-12-28 JP JP56209840A patent/JPS57140725A/ja active Granted
-
1982
- 1982-04-07 EP EP82301853A patent/EP0090892B1/de not_active Expired
- 1982-04-07 AT AT82301853T patent/ATE23540T1/de not_active IP Right Cessation
- 1982-04-13 FR FR8206351A patent/FR2524891B1/fr not_active Expired
- 1982-04-14 BE BE0/207819A patent/BE892846A/fr not_active IP Right Cessation
- 1982-06-22 CA CA000405748A patent/CA1199579A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2524891B1 (fr) | 1988-01-08 |
BE892846A (fr) | 1982-10-14 |
JPS57140725A (en) | 1982-08-31 |
EP0090892B1 (de) | 1986-11-12 |
CA1199579A (en) | 1986-01-21 |
JPS6363558B2 (de) | 1988-12-07 |
FR2524891A1 (fr) | 1983-10-14 |
EP0090892A1 (de) | 1983-10-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EELA | Cancelled due to lapse of time |