ATE135711T1 - Antihypertensive derivate - Google Patents
Antihypertensive derivateInfo
- Publication number
- ATE135711T1 ATE135711T1 AT85111454T AT85111454T ATE135711T1 AT E135711 T1 ATE135711 T1 AT E135711T1 AT 85111454 T AT85111454 T AT 85111454T AT 85111454 T AT85111454 T AT 85111454T AT E135711 T1 ATE135711 T1 AT E135711T1
- Authority
- AT
- Austria
- Prior art keywords
- antihypertensive
- derivatives
- substituents
- chem
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/649,797 US4746676A (en) | 1984-09-12 | 1984-09-12 | Carboxyalkyl dipeptide compounds |
| US06/752,695 US4749698A (en) | 1985-07-08 | 1985-07-08 | Antihypertensive derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE135711T1 true ATE135711T1 (de) | 1996-04-15 |
Family
ID=27095707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85111454T ATE135711T1 (de) | 1984-09-12 | 1985-09-10 | Antihypertensive derivate |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0175266B1 (de) |
| KR (1) | KR860002464A (de) |
| AT (1) | ATE135711T1 (de) |
| AU (1) | AU578489B2 (de) |
| CA (1) | CA1288893C (de) |
| DE (1) | DE3588094T2 (de) |
| DK (1) | DK412985A (de) |
| ES (1) | ES8609364A1 (de) |
| FI (1) | FI89716C (de) |
| IL (1) | IL76345A (de) |
| IN (1) | IN164615B (de) |
| NO (1) | NO169442C (de) |
| NZ (1) | NZ213432A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629345A (en) * | 1993-07-23 | 1997-05-13 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| US5965620A (en) * | 1993-07-23 | 1999-10-12 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| WO1995034577A1 (en) * | 1994-06-16 | 1995-12-21 | Smithkline Beecham Corporation | Template directed cyclization |
| ATE324876T1 (de) † | 1999-10-14 | 2006-06-15 | Curis Inc | VERMITTLER VON ßHEDGEHOGß ÜBERMITTELNDEN BAHNEN, DAZUGEHÖRIGE ZUSAMMENETZUNGEN UND VERWENDUNGEN |
| DE50015940D1 (de) | 2000-09-21 | 2010-07-29 | Abb Schweiz Ag | Konfiguration eines Leitsystems einer elektrischen Schaltanlage |
| WO2007078990A2 (en) * | 2005-12-23 | 2007-07-12 | Zealand Pharma A/S | Modified lysine-mimetic compounds |
| EP2074087A2 (de) | 2006-12-21 | 2009-07-01 | Wyeth | Synthese von pyrrolidinverbindungen |
| CN110709096B (zh) | 2017-05-05 | 2023-10-31 | 泽兰德制药公司 | 细胞间隙连接通讯调节剂及其在糖尿病性眼病治疗中的应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5683483A (en) * | 1979-12-13 | 1981-07-08 | Santen Pharmaceut Co Ltd | Thiazolidine compound |
| US4350704A (en) * | 1980-10-06 | 1982-09-21 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids |
| EP0048159A3 (de) * | 1980-09-17 | 1982-05-12 | University Of Miami | Carboxyalkyl-Peptide und Thioäther und Äther von Peptiden als antihypertensive Mittel |
| US4462943A (en) * | 1980-11-24 | 1984-07-31 | E. R. Squibb & Sons, Inc. | Carboxyalkyl amino acid derivatives of various substituted prolines |
| FR2501399B1 (fr) * | 1981-03-03 | 1987-06-19 | France Etat | Dispositif d'affichage de messages graphiques transmis par des systemes de videotex |
| EP0080822A1 (de) * | 1981-11-27 | 1983-06-08 | Beecham Group Plc | Antihypertensive auf Prolin basierende Peptide |
| EP0088350B1 (de) * | 1982-03-08 | 1985-02-20 | Schering Corporation | Carboxyalkyl-Dipeptiden, Verfahren zu deren Herstellung und deren pharmazeutische Zusammensetzungen |
| ZA832762B (en) * | 1982-04-30 | 1983-12-28 | Squibb & Sons Inc | Substituted 4-phenoxy prolines |
| IL69136A0 (en) * | 1982-07-19 | 1983-10-31 | Squibb & Sons Inc | Substituted peptide compounds |
| US4623729A (en) * | 1982-07-22 | 1986-11-18 | E. R. Squibb & Sons, Inc. | Acylalkylaminocarbonyl substituted amino and imino acid compounds |
| US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
| FI841052A (fi) * | 1983-03-16 | 1984-09-17 | Usv Pharma Corp | Foereningar foer behandling av blodtryckssjukdomar. |
| EP0127124A3 (de) * | 1983-05-23 | 1987-04-08 | Usv Pharmaceutical Corporation | Verbindungen zur Behandlung von hohem Blutdruck |
-
1985
- 1985-09-10 DE DE3588094T patent/DE3588094T2/de not_active Expired - Fee Related
- 1985-09-10 AT AT85111454T patent/ATE135711T1/de not_active IP Right Cessation
- 1985-09-10 IL IL76345A patent/IL76345A/xx unknown
- 1985-09-10 EP EP85111454A patent/EP0175266B1/de not_active Expired - Lifetime
- 1985-09-10 AU AU47331/85A patent/AU578489B2/en not_active Ceased
- 1985-09-11 ES ES546866A patent/ES8609364A1/es not_active Expired
- 1985-09-11 NO NO853551A patent/NO169442C/no unknown
- 1985-09-11 DK DK412985A patent/DK412985A/da not_active Application Discontinuation
- 1985-09-11 NZ NZ213432A patent/NZ213432A/xx unknown
- 1985-09-11 CA CA000490437A patent/CA1288893C/en not_active Expired - Lifetime
- 1985-09-11 KR KR1019850006633A patent/KR860002464A/ko not_active Application Discontinuation
- 1985-09-12 FI FI853494A patent/FI89716C/fi not_active IP Right Cessation
- 1985-09-16 IN IN652/CAL/85A patent/IN164615B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1288893C (en) | 1991-09-10 |
| NO853551L (no) | 1986-03-13 |
| KR860002464A (ko) | 1986-04-26 |
| DK412985D0 (da) | 1985-09-11 |
| NO169442C (no) | 1992-06-24 |
| DK412985A (da) | 1986-03-13 |
| DE3588094D1 (de) | 1996-04-25 |
| IN164615B (de) | 1989-04-22 |
| FI89716C (fi) | 1993-11-10 |
| FI853494L (fi) | 1986-03-13 |
| EP0175266A2 (de) | 1986-03-26 |
| AU4733185A (en) | 1986-03-20 |
| FI89716B (fi) | 1993-07-30 |
| NZ213432A (en) | 1988-11-29 |
| ES546866A0 (es) | 1986-07-16 |
| AU578489B2 (en) | 1988-10-27 |
| FI853494A0 (fi) | 1985-09-12 |
| EP0175266A3 (en) | 1988-08-03 |
| ES8609364A1 (es) | 1986-07-16 |
| IL76345A0 (en) | 1986-01-31 |
| EP0175266B1 (de) | 1996-03-20 |
| NO169442B (no) | 1992-03-16 |
| IL76345A (en) | 1988-12-30 |
| DE3588094T2 (de) | 1996-08-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE70833T1 (de) | Piperazinyl-heterocyclische derivate. | |
| DE68913022T2 (de) | Heterozyklische Derivate. | |
| DK0386675T3 (da) | Xanthinderivater | |
| DE58904761D1 (de) | Chirale derivate des 1,2 -difluorbenzols. | |
| ATE75743T1 (de) | Hydrazinderivate und ihre verwendung. | |
| FI863833A (fi) | Imidazolinyl-derivat, foerfaranden foer deras framstaellning och dessa foereningar innehaollande medel med herbicid verkan. | |
| ATE135711T1 (de) | Antihypertensive derivate | |
| DK521685A (da) | Spergualin-derivater og anvendelse deraf til fremstilling af laegemidler med immunosuppressiv virkning | |
| DE68912007T2 (de) | Antiparasitäre Derivate. | |
| ES8704875A1 (es) | Procedimiento de producir compuestos para tratar la hiper- tension | |
| DE58903514D1 (de) | Derivate der 2,3-difluorbenzoesaeure. | |
| ATE102624T1 (de) | Makrolide derivate. | |
| ATE54151T1 (de) | Erythromycylamin-derivate. | |
| ES8602021A1 (es) | Procedimiento de preparar compuestos espirociclicos antihi- pertensivos | |
| DE3771597D1 (de) | Pyridazinon derivate und ihre salze. | |
| DE3686632T2 (de) | Antibiotische derivate, ihre herstellung und verwendung. | |
| ATE23151T1 (de) | Derivate des 1,4-dihydropyridins. | |
| ATE54912T1 (de) | Mevalonolactonaehnliche imidazole und derivate. | |
| ATE101395T1 (de) | Heterozyklische derivate. | |
| SU1432991A1 (ru) | 4-Метил-5-(4-метилфениламино)-1,2,3-триазол, обладающий противовоспалительной активностью | |
| ATE80163T1 (de) | Antibiotische derivate, ihre herstellung und verwendung. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |