ATE131812T1 - Verfahren zur totalen synthese von einer indol- struktur-verbindungsklasse des tryptamin-typs, insbesondere melatonin- oder n-acetyl-5- methoxytryptamin mit hoher reinheit und löslichkeit, verwendbar in der aids-therapie - Google Patents
Verfahren zur totalen synthese von einer indol- struktur-verbindungsklasse des tryptamin-typs, insbesondere melatonin- oder n-acetyl-5- methoxytryptamin mit hoher reinheit und löslichkeit, verwendbar in der aids-therapieInfo
- Publication number
- ATE131812T1 ATE131812T1 AT89830055T AT89830055T ATE131812T1 AT E131812 T1 ATE131812 T1 AT E131812T1 AT 89830055 T AT89830055 T AT 89830055T AT 89830055 T AT89830055 T AT 89830055T AT E131812 T1 ATE131812 T1 AT E131812T1
- Authority
- AT
- Austria
- Prior art keywords
- acetyl
- melatonine
- methoxytriptamine
- order
- total synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19549/88A IT1217344B (it) | 1988-02-25 | 1988-02-25 | Farmaco per la cura delle sindrome di immunodeficienza acquisita |
IT8821872A IT1230493B (it) | 1988-09-08 | 1988-09-08 | Procedimento di sintesi totale, per l'ottenimento di una categoria di prodotti derivati a struttura indolica del tipo della triptamina in particolare di melatonina o n-aceti 5-metossitriptamina ad elevato grado di purezza e facilmente solubile utilizzabile in specie per impieghi terapeutici e quale farmaco per la cura delle sindromi da |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE131812T1 true ATE131812T1 (de) | 1996-01-15 |
Family
ID=26327207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89830055T ATE131812T1 (de) | 1988-02-25 | 1989-02-16 | Verfahren zur totalen synthese von einer indol- struktur-verbindungsklasse des tryptamin-typs, insbesondere melatonin- oder n-acetyl-5- methoxytryptamin mit hoher reinheit und löslichkeit, verwendbar in der aids-therapie |
Country Status (7)
Country | Link |
---|---|
US (2) | US5122535A (de) |
EP (1) | EP0330625B1 (de) |
JP (1) | JP2724493B2 (de) |
AT (1) | ATE131812T1 (de) |
DE (1) | DE68925135T2 (de) |
ES (1) | ES2083390T3 (de) |
GR (1) | GR3019365T3 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2830010A1 (fr) * | 2001-09-27 | 2003-03-28 | Atofina | Procede de preparation de n-(omega-bromoalkyl)phtalimides |
FR2830011A1 (fr) * | 2001-09-27 | 2003-03-28 | Atofina | Procede de preparation de n-(omega-bromoalkyl)phtalimides |
KR100411599B1 (ko) * | 2001-10-23 | 2003-12-18 | 동방에프티엘 주식회사 | 5-치환된 인돌 유도체의 제조방법 |
US20050020666A1 (en) * | 2003-07-25 | 2005-01-27 | Dabur Research Foundation | Cardioprotective agents |
WO2012035406A1 (en) * | 2010-09-14 | 2012-03-22 | Council Of Scientific & Industrial Research | Tryptamine derivatives, their preparation and their use in gastropathy |
CN110818610B (zh) * | 2019-12-06 | 2021-03-23 | 杭州志源生物科技有限公司 | 褪黑素的制备方法 |
CN115010645B (zh) * | 2022-06-21 | 2023-08-29 | 广西师范大学 | 一种褪黑素的制备方法 |
WO2024138007A2 (en) * | 2022-12-21 | 2024-06-27 | Caamtech, Inc. | Tryptamine derivatives |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2248155A (en) * | 1938-06-28 | 1941-07-08 | Merck & Co Inc | Process for the production of indole acids |
US2416258A (en) * | 1944-03-17 | 1947-02-18 | Purdue Research Foundation | 3-(5-ethoxy-3-indolyl)-propyl compounds |
CH585199A5 (de) * | 1972-09-15 | 1977-02-28 | Siegfried Ag | |
DE3105850A1 (de) * | 1981-02-18 | 1982-08-19 | Horst, Hans Jörg, Priv.Doz.Dr., 2057 Reinbek | Mittel zum behandeln von tumoren |
-
1989
- 1989-02-16 EP EP89830055A patent/EP0330625B1/de not_active Expired - Lifetime
- 1989-02-16 ES ES89830055T patent/ES2083390T3/es not_active Expired - Lifetime
- 1989-02-16 AT AT89830055T patent/ATE131812T1/de not_active IP Right Cessation
- 1989-02-16 DE DE68925135T patent/DE68925135T2/de not_active Expired - Fee Related
- 1989-02-17 US US07/312,627 patent/US5122535A/en not_active Ceased
- 1989-02-23 JP JP1045068A patent/JP2724493B2/ja not_active Expired - Lifetime
-
1994
- 1994-06-02 US US08/252,905 patent/USRE35631E/en not_active Expired - Lifetime
-
1996
- 1996-03-19 GR GR960400765T patent/GR3019365T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5122535A (en) | 1992-06-16 |
DE68925135T2 (de) | 1996-08-01 |
EP0330625A3 (de) | 1991-09-18 |
GR3019365T3 (en) | 1996-06-30 |
DE68925135D1 (de) | 1996-02-01 |
USRE35631E (en) | 1997-10-14 |
ES2083390T3 (es) | 1996-04-16 |
JP2724493B2 (ja) | 1998-03-09 |
JPH023680A (ja) | 1990-01-09 |
EP0330625A2 (de) | 1989-08-30 |
EP0330625B1 (de) | 1995-12-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |