ATE130096T1 - Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung. - Google Patents
Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung.Info
- Publication number
- ATE130096T1 ATE130096T1 AT91913539T AT91913539T ATE130096T1 AT E130096 T1 ATE130096 T1 AT E130096T1 AT 91913539 T AT91913539 T AT 91913539T AT 91913539 T AT91913539 T AT 91913539T AT E130096 T1 ATE130096 T1 AT E130096T1
- Authority
- AT
- Austria
- Prior art keywords
- amplifying
- emission signal
- luminescent compound
- luminescent
- compound
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Luminescent Compositions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9008981A FR2664699B1 (fr) | 1990-07-13 | 1990-07-13 | Procede d'amplification du signal d'emission d'un compose luminescent. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE130096T1 true ATE130096T1 (de) | 1995-11-15 |
Family
ID=9398708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91913539T ATE130096T1 (de) | 1990-07-13 | 1991-07-12 | Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5512493A (de) |
EP (1) | EP0539477B1 (de) |
JP (1) | JP3117459B2 (de) |
AT (1) | ATE130096T1 (de) |
AU (1) | AU8198091A (de) |
DE (1) | DE69114499T2 (de) |
DK (1) | DK0539477T3 (de) |
ES (1) | ES2082217T3 (de) |
FR (1) | FR2664699B1 (de) |
GR (1) | GR3018429T3 (de) |
WO (1) | WO1992001225A1 (de) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6399397B1 (en) | 1992-09-14 | 2002-06-04 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
US6159686A (en) | 1992-09-14 | 2000-12-12 | Sri International | Up-converting reporters for biological and other assays |
US5736410A (en) | 1992-09-14 | 1998-04-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
US6238931B1 (en) * | 1993-09-24 | 2001-05-29 | Biosite Diagnostics, Inc. | Fluorescence energy transfer in particles |
FR2735238B1 (fr) * | 1995-06-09 | 1997-09-05 | Cis Bio Int | Utilisation d'un complexe phycobiliproteine-peptide de liaison en tant que traceur fluorescent |
FI963989A (fi) * | 1996-10-04 | 1998-04-05 | Wallac Oy | Homogeenisiä määritysmenetelmiä, jotka perustuvat luminesenssienergiasiirtoon |
US20050227294A1 (en) * | 1997-09-15 | 2005-10-13 | Molecular Devices Corporation | Molecular modification assays involving lipids |
US7745142B2 (en) | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
US7632651B2 (en) * | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
FR2769315B1 (fr) * | 1997-10-03 | 2001-06-08 | Cis Bio Int | Conjugues fluorescents de nucleosides ou de nucleotides, leur procede de preparation et leur utilisation |
AU2679899A (en) | 1998-02-18 | 1999-09-06 | Dade Behring Inc. | Chemiluminescent compositions for use in detection of multiple analytes |
EP1925320A3 (de) | 1998-03-27 | 2008-09-03 | Prolume, Ltd. | Luciferasen, fluoreszierende Proteine, Nukleinsäuren zur Kodierung der Luciferasen und der fluoreszierenden Proteine sowie deren Verwendung zur Diagnose, zum Screening mit hohem Durchsatz und zur Behandlung neuartiger Probleme |
FR2778744B1 (fr) | 1998-05-14 | 2000-06-23 | Cis Bio Int | Dosage immunologique de la chromogranine a humaine (cga) anticorps, reactifs et trousses utilisables pour ce dosage |
US5998146A (en) * | 1998-07-17 | 1999-12-07 | Wallac Oy | Homogeneous luminescence assay method based on energy transfer |
US6235479B1 (en) | 1999-04-13 | 2001-05-22 | Bio Merieux, Inc. | Methods and devices for performing analysis of a nucleic acid sample |
FR2809817B1 (fr) * | 2000-06-02 | 2003-08-15 | Cis Bio Int | Procede de detection de presence d'un liquide dans un melange |
DE10153829A1 (de) | 2001-11-05 | 2003-05-28 | Bayer Ag | Assay basierend auf dotierten Nanoteilchen |
EP1355158A1 (de) | 2002-04-19 | 2003-10-22 | B.R.A.H.M.S Aktiengesellschaft | Verfahren zur Diagnose von Entzündungserkrankungen und Infektionen unter Bestimmung des Phosphoproteins LASP-1 als Inflammationsmarker |
EP1355159A1 (de) * | 2002-04-19 | 2003-10-22 | B.R.A.H.M.S Aktiengesellschaft | Verwendungen von Fragmenten der Carbamoylphosphat Synthetase 1 (CPS 1) für die Diagnose von Entzündungserkrankungen und Sepsis |
WO2004042019A2 (en) * | 2002-10-30 | 2004-05-21 | Pointilliste, Inc. | Systems for capture and analysis of biological particles and methods using the systems |
US20040241748A1 (en) * | 2003-02-10 | 2004-12-02 | Dana Ault-Riche | Self-assembling arrays and uses thereof |
US20050095648A1 (en) * | 2003-10-30 | 2005-05-05 | Mario Geysen | Method for designing linear epitopes and algorithm therefor and polypeptide epitopes |
US20060018911A1 (en) * | 2004-01-12 | 2006-01-26 | Dana Ault-Riche | Design of therapeutics and therapeutics |
US20060024757A1 (en) * | 2004-07-30 | 2006-02-02 | Robert Hussa | Detection of oncofetal fibronectin for selection of concepti |
DE102004045705A1 (de) | 2004-09-21 | 2006-04-06 | B.R.A.H.M.S Ag | Verwendungen der Carbamoylphosphat Synthetase 1(CPS) als humoraler Biomarker für die Diagnose von Tumorerkrankungen und chronisch entzündlichen Darmerkrankungen |
CA2581639C (en) * | 2004-09-30 | 2016-07-26 | Molecular Devices Corporation | Luminescent lanthanide complexes |
DE102006021406B4 (de) | 2006-05-08 | 2008-08-07 | B.R.A.H.M.S Aktiengesellschaft | In vitro Verfahren zur Früherkennung von arznei- und suchtmittelinduzierten Leberschäden und zur Erkennung der bereits erreichten Stufe der Leberschädigung |
DE102007009751A1 (de) | 2007-02-28 | 2008-09-04 | B.R.A.H.M.S Aktiengesellschaft | Verfahren zur selektiven Bestimmung von Procalcitonin 1-116 für diagnostische Zwecke sowie Antikörper und Kits zur Durchführung eines solchen Verfahrens |
DE102007022367A1 (de) | 2007-05-07 | 2008-11-20 | B.R.A.H.M.S Ag | Verfahren zur Bestimmung von aminoterminalen pro-ANP bei übergewichtigen Patienten |
US20130183696A1 (en) | 2010-09-15 | 2013-07-18 | Constance Neely Wilson | Methods of use and kit for measurement of lipopolysaccharide with a time resolved fluorescence based assay |
US9653691B2 (en) * | 2012-12-12 | 2017-05-16 | Universal Display Corporation | Phosphorescence-sensitizing fluorescence material system |
WO2016063304A1 (en) | 2014-10-21 | 2016-04-28 | Council Of Scientific & Industrial Research | Luminescent lanthanide complexes and method of preparation thereof |
US10138267B2 (en) | 2015-04-06 | 2018-11-27 | Hunan Skyworld Biotechnologies Co. Ltd. | Bioconjugates of heterocyclic compounds |
US20180348235A1 (en) | 2015-11-27 | 2018-12-06 | B.R.A.H.M.S Gmbh | MR-proADM as marker for the extracellular volume status of a subject |
AU2017210215B2 (en) | 2016-01-21 | 2022-09-08 | SeLux Diagnostics, Inc. | Methods for rapid antimicrobial susceptibility testing |
US9834808B2 (en) | 2016-01-21 | 2017-12-05 | SeLux Diagnostics, Inc. | Methods for rapid antibiotic susceptibility testing |
FR3051556A1 (fr) * | 2016-05-18 | 2017-11-24 | Biocytex | Utilisation de marqueurs fluorescents pour la detection de cible biologique dans un echantillon |
WO2018029213A1 (en) | 2016-08-09 | 2018-02-15 | B.R.A.H.M.S Gmbh | Histones and/or proadm as markers indicating organ dysfunction |
JP7104689B2 (ja) | 2016-08-09 | 2022-07-21 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 有害事象を示すマーカーとしてのヒストンおよび/またはproADM |
BR112019012979A2 (pt) | 2016-12-23 | 2019-12-31 | Selux Diagnostics Inc | métodos para o teste de suscetibilidade antimicrobiana rápida melhorada |
CA3052349A1 (en) | 2017-02-02 | 2018-08-09 | B.R.A.H.M.S Gmbh | Proadm as marker indicating an adverse event |
US20200225248A1 (en) | 2017-05-31 | 2020-07-16 | B.R.A.H.M.S Gmbh | Mmp-8 as a marker for identifying infectious disease |
CN111065922A (zh) | 2017-09-13 | 2020-04-24 | B.R.A.H.M.S有限公司 | 肾上腺髓质素原作为危重病患者的肾脏替代治疗的指标 |
CA3075440A1 (en) | 2017-09-13 | 2019-03-21 | B.R.A.H.M.S Gmbh | Pro-adm as a therapy monitoring marker for critcally ill patients |
ES2909399T3 (es) | 2017-09-13 | 2022-05-06 | Brahms Gmbh | Proadrenomedulina como marcador de niveles anormales de plaquetas |
DK3682241T3 (da) | 2017-09-13 | 2022-05-16 | Brahms Gmbh | Pct og pro-adm som markører til monitorering af antibiotikabehandling |
EP3502691A1 (de) | 2017-12-20 | 2019-06-26 | B.R.A.H.M.S GmbH | Proadrenomedullin als indikator für nierenersatztherapie bei kritisch kranken patienten |
JP7344208B2 (ja) | 2017-12-20 | 2023-09-13 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | pro-ADMに基づく抗生物質療法の指導 |
JP7444776B2 (ja) | 2017-12-20 | 2024-03-06 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 併存症を有する患者におけるプロカルシトニンに基づく抗生物質療法のガイダンス |
EP3578989A1 (de) | 2018-06-06 | 2019-12-11 | B.R.A.H.M.S GmbH | Pro-adm zur prognose von traumabedingten komplikationen bei polytraumapatienten |
EP3608673A1 (de) | 2018-08-08 | 2020-02-12 | B.R.A.H.M.S GmbH | Pro-adm zur prognose des risikos einer erkrankung, die einen krankenhausaufenthalt bei patienten mit symptomen einer infektionskrankheit erfordert |
WO2020156988A1 (en) | 2019-01-28 | 2020-08-06 | B.R.A.H.M.S Gmbh | Method to predict treatment response in patients with nocturnal enuresis |
CA3126202A1 (en) | 2019-02-21 | 2020-08-27 | B.R.A.H.M.S Gmbh | Diagnosis or prognosis of postsurgical adverse events |
CA3124744A1 (en) | 2019-03-29 | 2020-10-08 | B.R.A.H.M.S Gmbh | Prescription of remote patient management based on biomarkers |
EP3715851A1 (de) | 2019-03-29 | 2020-09-30 | B.R.A.H.M.S GmbH | Verschreibung von fernpatientenmanagement auf der basis von biomarkern |
CA3152541A1 (en) | 2019-08-27 | 2021-03-04 | SeLux Diagnostics, Inc. | Systems and methods for performing antimicrobial susceptibility testing |
BR112022017489A2 (pt) | 2020-04-06 | 2022-10-18 | Brahms Gmbh | Pró adrenomedulina para prognóstico da progressão da doença na síndrome respiratória aguda grave (sars) |
WO2021204984A1 (en) | 2020-04-09 | 2021-10-14 | B.R.A.H.M.S Gmbh | Biomarkers for the diagnosis of respiratory tract infections |
WO2023104975A1 (en) | 2021-12-08 | 2023-06-15 | B.R.A.H.M.S Gmbh | Biomarkers for prognosis of early onset preeclampsia |
WO2023110832A1 (en) | 2021-12-13 | 2023-06-22 | UNIVERSITé LAVAL | Biomarkers for the prediction of preterm birth |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4542104A (en) * | 1983-04-06 | 1985-09-17 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Phycobiliprotein fluorescent conjugates |
FR2570703B1 (fr) * | 1984-09-26 | 1988-07-08 | Commissariat Energie Atomique | Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents |
JPS61128169A (ja) * | 1984-11-27 | 1986-06-16 | Mitsubishi Chem Ind Ltd | 免疫分析法 |
US4822733A (en) * | 1985-05-28 | 1989-04-18 | Amoco Corporation | Lifetime-resolved assay procedures |
EP0272320B1 (de) * | 1986-06-17 | 1994-03-23 | Baxter Diagnostics Inc. | Homogenes fluortestverfahren mit abstoss des fluorzenten hintergrundes. |
FR2624862B1 (fr) * | 1987-12-18 | 1990-06-08 | Oris Ind | Cryptates de terres rares, procedes d'obtention, intermediaires de synthese et application a titre de marqueurs fluorescents |
GB8820887D0 (en) * | 1988-09-06 | 1988-10-05 | Atomic Energy Authority Uk | Detecting selected species |
-
1990
- 1990-07-13 FR FR9008981A patent/FR2664699B1/fr not_active Expired - Fee Related
-
1991
- 1991-07-12 JP JP03512207A patent/JP3117459B2/ja not_active Expired - Fee Related
- 1991-07-12 AU AU81980/91A patent/AU8198091A/en not_active Abandoned
- 1991-07-12 AT AT91913539T patent/ATE130096T1/de not_active IP Right Cessation
- 1991-07-12 ES ES91913539T patent/ES2082217T3/es not_active Expired - Lifetime
- 1991-07-12 EP EP91913539A patent/EP0539477B1/de not_active Expired - Lifetime
- 1991-07-12 DK DK91913539.2T patent/DK0539477T3/da active
- 1991-07-12 WO PCT/FR1991/000567 patent/WO1992001225A1/fr active IP Right Grant
- 1991-07-12 DE DE69114499T patent/DE69114499T2/de not_active Expired - Lifetime
-
1993
- 1993-05-26 US US08/068,843 patent/US5512493A/en not_active Expired - Lifetime
-
1995
- 1995-12-15 GR GR950403559T patent/GR3018429T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69114499D1 (de) | 1995-12-14 |
WO1992001225A1 (fr) | 1992-01-23 |
FR2664699B1 (fr) | 1995-08-18 |
DK0539477T3 (da) | 1995-12-11 |
EP0539477B1 (de) | 1995-11-08 |
US5512493A (en) | 1996-04-30 |
JPH06500852A (ja) | 1994-01-27 |
EP0539477A1 (de) | 1993-05-05 |
FR2664699A1 (fr) | 1992-01-17 |
GR3018429T3 (en) | 1996-03-31 |
ES2082217T3 (es) | 1996-03-16 |
DE69114499T2 (de) | 1996-03-28 |
JP3117459B2 (ja) | 2000-12-11 |
AU8198091A (en) | 1992-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EELA | Cancelled due to lapse of time |