DE69114499D1 - Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung. - Google Patents

Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung.

Info

Publication number
DE69114499D1
DE69114499D1 DE69114499T DE69114499T DE69114499D1 DE 69114499 D1 DE69114499 D1 DE 69114499D1 DE 69114499 T DE69114499 T DE 69114499T DE 69114499 T DE69114499 T DE 69114499T DE 69114499 D1 DE69114499 D1 DE 69114499D1
Authority
DE
Germany
Prior art keywords
luminescent
amplifying
emission signal
connection
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69114499T
Other languages
English (en)
Other versions
DE69114499T2 (de
Inventor
Gerard Mathis
Christophe Dumont
Daniel Aspe
Muriel Foyentin
Etienne Jolu
Dominique Nuti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Publication of DE69114499D1 publication Critical patent/DE69114499D1/de
Application granted granted Critical
Publication of DE69114499T2 publication Critical patent/DE69114499T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69114499T 1990-07-13 1991-07-12 Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung. Expired - Lifetime DE69114499T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9008981A FR2664699B1 (fr) 1990-07-13 1990-07-13 Procede d'amplification du signal d'emission d'un compose luminescent.
PCT/FR1991/000567 WO1992001225A1 (fr) 1990-07-13 1991-07-12 Procede d'amplification du signal d'emission d'un compose luminescent

Publications (2)

Publication Number Publication Date
DE69114499D1 true DE69114499D1 (de) 1995-12-14
DE69114499T2 DE69114499T2 (de) 1996-03-28

Family

ID=9398708

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69114499T Expired - Lifetime DE69114499T2 (de) 1990-07-13 1991-07-12 Verfahren zur verstärkung des emissionssignals einer lumineszierenden verbindung.

Country Status (11)

Country Link
US (1) US5512493A (de)
EP (1) EP0539477B1 (de)
JP (1) JP3117459B2 (de)
AT (1) ATE130096T1 (de)
AU (1) AU8198091A (de)
DE (1) DE69114499T2 (de)
DK (1) DK0539477T3 (de)
ES (1) ES2082217T3 (de)
FR (1) FR2664699B1 (de)
GR (1) GR3018429T3 (de)
WO (1) WO1992001225A1 (de)

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FR2778744B1 (fr) 1998-05-14 2000-06-23 Cis Bio Int Dosage immunologique de la chromogranine a humaine (cga) anticorps, reactifs et trousses utilisables pour ce dosage
US5998146A (en) * 1998-07-17 1999-12-07 Wallac Oy Homogeneous luminescence assay method based on energy transfer
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
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AU2003287384A1 (en) * 2002-10-30 2004-06-07 Pointilliste, Inc. Systems for capture and analysis of biological particles and methods using the systems
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US20050095648A1 (en) * 2003-10-30 2005-05-05 Mario Geysen Method for designing linear epitopes and algorithm therefor and polypeptide epitopes
WO2005067980A2 (en) * 2004-01-12 2005-07-28 Pointilliste, Inc. Design of therapeutics and therapeutics
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DE102004045705A1 (de) * 2004-09-21 2006-04-06 B.R.A.H.M.S Ag Verwendungen der Carbamoylphosphat Synthetase 1(CPS) als humoraler Biomarker für die Diagnose von Tumorerkrankungen und chronisch entzündlichen Darmerkrankungen
EP1805188A4 (de) * 2004-09-30 2010-03-03 Mds Analytical Technologies Us Lumineszente lanthanidkomplexe
DE102006021406B4 (de) 2006-05-08 2008-08-07 B.R.A.H.M.S Aktiengesellschaft In vitro Verfahren zur Früherkennung von arznei- und suchtmittelinduzierten Leberschäden und zur Erkennung der bereits erreichten Stufe der Leberschädigung
DE102007009751A1 (de) 2007-02-28 2008-09-04 B.R.A.H.M.S Aktiengesellschaft Verfahren zur selektiven Bestimmung von Procalcitonin 1-116 für diagnostische Zwecke sowie Antikörper und Kits zur Durchführung eines solchen Verfahrens
DE102007022367A1 (de) 2007-05-07 2008-11-20 B.R.A.H.M.S Ag Verfahren zur Bestimmung von aminoterminalen pro-ANP bei übergewichtigen Patienten
US20130183696A1 (en) 2010-09-15 2013-07-18 Constance Neely Wilson Methods of use and kit for measurement of lipopolysaccharide with a time resolved fluorescence based assay
US9653691B2 (en) * 2012-12-12 2017-05-16 Universal Display Corporation Phosphorescence-sensitizing fluorescence material system
WO2016063304A1 (en) 2014-10-21 2016-04-28 Council Of Scientific & Industrial Research Luminescent lanthanide complexes and method of preparation thereof
US10138267B2 (en) 2015-04-06 2018-11-27 Hunan Skyworld Biotechnologies Co. Ltd. Bioconjugates of heterocyclic compounds
BR112018010269A2 (pt) 2015-11-27 2019-02-05 Brahms Gmbh mr-proadm como marcador para o status do volume extracelular de um indivíduo
US9834808B2 (en) 2016-01-21 2017-12-05 SeLux Diagnostics, Inc. Methods for rapid antibiotic susceptibility testing
MX2018008906A (es) 2016-01-21 2019-01-10 Selux Diagnostics Inc Metodos para pruebas rapidas de susceptibilidad antimicrobiana.
FR3051556A1 (fr) * 2016-05-18 2017-11-24 Biocytex Utilisation de marqueurs fluorescents pour la detection de cible biologique dans un echantillon
US20190178894A1 (en) 2016-08-09 2019-06-13 B.R.A.H.M.S Gmbh Histones and/or proadm as markers indicating an adverse event
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CN111094986B (zh) 2017-09-13 2023-11-10 B.R.A.H.M.S有限公司 基于肾上腺髓质素前体的指导流体治疗的方法
WO2019053124A1 (en) 2017-09-13 2019-03-21 B.R.A.H.M.S Gmbh PROADRENOMEDULINE AS AN INDICATOR FOR RENAL REPLACEMENT THERAPY IN SERIOUSLY PATIENT PATIENTS
EP3502691A1 (de) 2017-12-20 2019-06-26 B.R.A.H.M.S GmbH Proadrenomedullin als indikator für nierenersatztherapie bei kritisch kranken patienten
EP3971573A1 (de) 2017-09-13 2022-03-23 B.R.A.H.M.S GmbH Proadrenomedullin als marker für anormale thrombozytenspiegel
US20200319212A1 (en) 2017-12-20 2020-10-08 B.R.A.H.M.S Gmbh Antibiotic therapy guidance based on procalcitonin in patients with comorbidities
WO2019122089A1 (en) 2017-12-20 2019-06-27 B.R.A.H.M.S Gmbh Antibiotic therapy guidance based on pro-adm
EP3578989A1 (de) 2018-06-06 2019-12-11 B.R.A.H.M.S GmbH Pro-adm zur prognose von traumabedingten komplikationen bei polytraumapatienten
EP3608673A1 (de) 2018-08-08 2020-02-12 B.R.A.H.M.S GmbH Pro-adm zur prognose des risikos einer erkrankung, die einen krankenhausaufenthalt bei patienten mit symptomen einer infektionskrankheit erfordert
WO2020156988A1 (en) 2019-01-28 2020-08-06 B.R.A.H.M.S Gmbh Method to predict treatment response in patients with nocturnal enuresis
BR112021016597A2 (pt) 2019-02-21 2021-11-03 Brahms Gmbh Diagnóstico ou prognóstico de eventos adversos pós-cirúrgicos
CA3124744A1 (en) 2019-03-29 2020-10-08 B.R.A.H.M.S Gmbh Prescription of remote patient management based on biomarkers
EP3715851A1 (de) 2019-03-29 2020-09-30 B.R.A.H.M.S GmbH Verschreibung von fernpatientenmanagement auf der basis von biomarkern
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WO2021204770A1 (en) 2020-04-06 2021-10-14 B.R.A.H.M.S Gmbh Pro-adrenomedullin for prognosing disease progression in severe acute respiratory syndrome (sars)
WO2021204984A1 (en) 2020-04-09 2021-10-14 B.R.A.H.M.S Gmbh Biomarkers for the diagnosis of respiratory tract infections
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Also Published As

Publication number Publication date
FR2664699B1 (fr) 1995-08-18
EP0539477A1 (de) 1993-05-05
GR3018429T3 (en) 1996-03-31
JPH06500852A (ja) 1994-01-27
EP0539477B1 (de) 1995-11-08
US5512493A (en) 1996-04-30
ATE130096T1 (de) 1995-11-15
JP3117459B2 (ja) 2000-12-11
FR2664699A1 (fr) 1992-01-17
DK0539477T3 (da) 1995-12-11
WO1992001225A1 (fr) 1992-01-23
AU8198091A (en) 1992-02-04
DE69114499T2 (de) 1996-03-28
ES2082217T3 (es) 1996-03-16

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