ATE126597T1 - Sensor mit einem antigen, das chemisch an eine halbleitervorrichtung gebunden ist. - Google Patents

Sensor mit einem antigen, das chemisch an eine halbleitervorrichtung gebunden ist.

Info

Publication number
ATE126597T1
ATE126597T1 AT90200915T AT90200915T ATE126597T1 AT E126597 T1 ATE126597 T1 AT E126597T1 AT 90200915 T AT90200915 T AT 90200915T AT 90200915 T AT90200915 T AT 90200915T AT E126597 T1 ATE126597 T1 AT E126597T1
Authority
AT
Austria
Prior art keywords
antigen
membrane
sensor
semiconductor device
chemically bonded
Prior art date
Application number
AT90200915T
Other languages
German (de)
English (en)
Inventor
Claudio Colapicchioni
Filippo Porcelli
Carlo Antonio Nuzzolo
Original Assignee
Eniricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa filed Critical Eniricerche Spa
Application granted granted Critical
Publication of ATE126597T1 publication Critical patent/ATE126597T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Bipolar Transistors (AREA)
AT90200915T 1989-04-21 1990-04-13 Sensor mit einem antigen, das chemisch an eine halbleitervorrichtung gebunden ist. ATE126597T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920259A IT1229691B (it) 1989-04-21 1989-04-21 Sensore con antigene legato chimicamente a un dispositivo semiconduttore.

Publications (1)

Publication Number Publication Date
ATE126597T1 true ATE126597T1 (de) 1995-09-15

Family

ID=11165221

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90200915T ATE126597T1 (de) 1989-04-21 1990-04-13 Sensor mit einem antigen, das chemisch an eine halbleitervorrichtung gebunden ist.

Country Status (9)

Country Link
US (1) US5160597A (ja)
EP (1) EP0395137B1 (ja)
JP (1) JPH02296142A (ja)
AT (1) ATE126597T1 (ja)
DE (1) DE69021621T2 (ja)
DK (1) DK0395137T3 (ja)
ES (1) ES2075135T3 (ja)
GR (1) GR3017224T3 (ja)
IT (1) IT1229691B (ja)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3809993A (en) * 1992-03-16 1993-10-21 Immuna Care Corporation Improved test kit for the determination of steroids and related compounds
CA2108705A1 (en) * 1992-11-06 1994-05-07 Richard Barner Biologically recognizing layers on new ti02 waveguide for biosensors
FR2722294B1 (fr) * 1994-07-07 1996-10-04 Lyon Ecole Centrale Procede d'analyse qualitative et/ou quantitative de substances biologiques presentes dans un milieu liquide conducteur et capteurs biochimiques d'affinite utilises pour la mise en oeuvre de ce procede
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
US6355436B1 (en) * 1996-05-17 2002-03-12 L'ecole Centrale De Lyon Method for analyzing biological substances in a conductive liquid medium
SE9602545L (sv) 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
US6699667B2 (en) 1997-05-14 2004-03-02 Keensense, Inc. Molecular wire injection sensors
US6060327A (en) * 1997-05-14 2000-05-09 Keensense, Inc. Molecular wire injection sensors
AU2583899A (en) 1998-02-04 1999-08-23 Invitrogen Corporation Microarrays and uses therefor
US6897073B2 (en) 1998-07-14 2005-05-24 Zyomyx, Inc. Non-specific binding resistant protein arrays and methods for making the same
US6682942B1 (en) 1998-07-14 2004-01-27 Zyomyx, Inc. Microdevices for screening biomolecules
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US20020119579A1 (en) * 1998-07-14 2002-08-29 Peter Wagner Arrays devices and methods of use thereof
US6576478B1 (en) 1998-07-14 2003-06-10 Zyomyx, Inc. Microdevices for high-throughput screening of biomolecules
US6967074B2 (en) * 2000-11-08 2005-11-22 Surface Logix, Inc. Methods of detecting immobilized biomolecules
US7371563B2 (en) * 2000-11-08 2008-05-13 Surface Logix, Inc. Peelable and resealable devices for biochemical assays
US7351575B2 (en) * 2000-11-08 2008-04-01 Surface Logix, Inc. Methods for processing biological materials using peelable and resealable devices
US6803205B2 (en) * 2000-11-08 2004-10-12 Surface Logix, Inc. Methods of measuring enzyme activity using peelable and resealable devices
US7439056B2 (en) 2000-11-08 2008-10-21 Surface Logix Inc. Peelable and resealable devices for arraying materials
US7001740B2 (en) * 2000-11-08 2006-02-21 Surface Logix, Inc. Methods of arraying biological materials using peelable and resealable devices
GB0105831D0 (en) * 2001-03-09 2001-04-25 Toumaz Technology Ltd Method for dna sequencing utilising enzyme linked field effect transistors
US20050053949A1 (en) * 2003-09-08 2005-03-10 Silin Vitalii Ivanovich Biochip for proteomics applications
US7318887B2 (en) * 2003-10-08 2008-01-15 Honeywell International Inc. Solid state reference electrode
US8198658B2 (en) * 2007-06-13 2012-06-12 Samsung Electronics Co., Ltd. Device and method for detecting biomolecules using adsorptive medium and field effect transistor
KR101465961B1 (ko) * 2007-10-09 2014-12-01 삼성전자주식회사 유전자 검출 방법 및 장치
US9029132B2 (en) 2009-08-06 2015-05-12 International Business Machines Corporation Sensor for biomolecules
US8052931B2 (en) 2010-01-04 2011-11-08 International Business Machines Corporation Ultra low-power CMOS based bio-sensor circuit
US9068935B2 (en) 2010-04-08 2015-06-30 International Business Machines Corporation Dual FET sensor for sensing biomolecules and charged ions in an electrolyte
EP2469275B1 (en) 2010-12-24 2015-12-23 Honeywell Romania S.R.L. Cantilevered carbon dioxide sensor
CA2862468A1 (en) 2012-01-23 2013-08-01 The Ohio State University Devices and methods for the rapid and accurate detection of analytes
WO2013114404A1 (en) * 2012-01-31 2013-08-08 Council Of Scientific & Industrial Research Nano-structured silver oxide film based aqueous voltammetric pesticide sensor and a process of preparing said sensor
US20230236147A1 (en) * 2020-05-27 2023-07-27 Jose Maria Piccinini Sensors and systems based on field-effect transistors, methods of preparation and devices for their operation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5825221B2 (ja) * 1977-12-12 1983-05-26 株式会社クラレ Ｆｅｔ比較電極
GB8314523D0 (en) * 1983-05-25 1983-06-29 Lowe C R Diagnostic device
GB8406955D0 (en) * 1984-03-16 1984-04-18 Serono Diagnostics Ltd Assay
US4708947A (en) * 1985-01-10 1987-11-24 Kuraray Co., Ltd. Water resistant composition and heat-sensitive recording sheet containing the same
JPH0721478B2 (ja) * 1986-03-31 1995-03-08 財団法人化学及血清療法研究所 免疫センサ−用作用膜
IT1215491B (it) * 1987-05-15 1990-02-14 Enricerche Spa Biosensore con membrana enzimatica legata chimicamente a un dispositivo semiconduttore.
US5001048A (en) * 1987-06-05 1991-03-19 Aurthur D. Little, Inc. Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film

Also Published As

Publication number Publication date
IT8920259A0 (it) 1989-04-21
ES2075135T3 (es) 1995-10-01
US5160597A (en) 1992-11-03
GR3017224T3 (en) 1995-11-30
DE69021621T2 (de) 1996-03-14
EP0395137A2 (en) 1990-10-31
DE69021621D1 (de) 1995-09-21
EP0395137A3 (en) 1991-06-12
JPH02296142A (ja) 1990-12-06
DK0395137T3 (da) 1995-11-06
EP0395137B1 (en) 1995-08-16
IT1229691B (it) 1991-09-06

Similar Documents

Publication Publication Date Title
ATE126597T1 (de) Sensor mit einem antigen, das chemisch an eine halbleitervorrichtung gebunden ist.
IT8222292A0 (it) Dispositivo per la rivelazione di radiazioni e dispositivo semiconduttore per l'impiego in tale dispositivo.
CY1108307T1 (el) Αντιγονα και εμβολια εντεροκοκκου
FR2651580B1 (fr) Dispositif de caracterisation dielectrique d'echantillons de materiau de surface plane ou non plane et application au controle non destructif de l'homogeneite dielectrique desdits echantillons.
FR2604166B1 (fr) Dispositif de chargement d'avions
IT9048246A0 (it) Procedimento per la lucidatura chimica meccanica bilaterale di fette di semiconduttori, nonche' dispositivo per la sua esecuzione, e fette di semiconduttori ottenibili con questo.
IT8421688A0 (it) Procedimento e dispositivo per diffondere una o una pluralita' di impurita' in un corpo di semiconduttore.
FR2566682B1 (fr) Dispositif pour proteger une surface d'un element lenticulaire en general, et d'une tranche de silicium en particulier, pendant que l'autre surface de celui-ci est soumise a un traitement chimique
SE9000245L (sv) Halvledarkomponent och foerfarande foer dess framstaellning
DE58901116D1 (de) Siliciumnitridpulver mit verbesserten oberflaecheneigenschaften sowie verfahren zu deren herstellung.
JPS57211222A (en) Method of marking semiconductor chip
SE8902148L (sv) Syntetiska peptid antigen foer detektion av htlv-1 infektion
FR2636438B1 (fr) Lentille de contact fabriquee en resine contenant du silicium et du fluor
DK0638175T3 (da) In vitro-test for Helicobacter pylori
ATE133499T1 (de) Lichtempfindliches element
DE3587542D1 (de) Verfahren zur Diagnose in vitro von menschlichen Cytomegalovirusinfektionen und Anwendung von monoklonalen Antikörpern gegen Cytomegaloviren, die mit einer cytomegalovirusinduzierten Proteinkinase reagieren.
IT8622560A0 (it) Polipeptidi immunologicamente attivi utili per la preparazione di vaccini antimalaria e di kitsdiagnostici per la determinazione di anticorpi antisporozoita.
ATE89862T1 (de) Monoklonaler antikoerper zur selektiven immunologischen bestimmung von intaktem prokollagen peptid (typ iii) und prokollagen (typ iii) in koerperfluessigkeiten.
EP0471844A4 (en) Silicon oxide film and semiconductor device having the same
ATE100201T1 (de) Fuehler mit einer immunochemischen membran, die mit einem halbleiter chemisch verbunden ist.
DE3763534D1 (de) Uebergabevorrichtung und uebergabeverfahren fuer halbleiterkassetten.
FR2601909B1 (fr) Siege d'automobile et appareil pour fabriquer celui-ci.
EP0485476A4 (en) Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
IT8785542A0 (it) Dispositivo per la sigillatura di buste in materia plastica o simili.
FR2631118B1 (fr) Dispositif capteur d'effort a six composantes, notamment pour la robotique