ATE125867T1 - Fibronektinbindungsprotein und dessen herstellung. - Google Patents

Fibronektinbindungsprotein und dessen herstellung.

Info

Publication number
ATE125867T1
ATE125867T1 AT90850166T AT90850166T ATE125867T1 AT E125867 T1 ATE125867 T1 AT E125867T1 AT 90850166 T AT90850166 T AT 90850166T AT 90850166 T AT90850166 T AT 90850166T AT E125867 T1 ATE125867 T1 AT E125867T1
Authority
AT
Austria
Prior art keywords
fibronectin binding
production
binding protein
protein
polypeptide
Prior art date
Application number
AT90850166T
Other languages
English (en)
Inventor
Magnus Hoeoek
Klas Joensson
Kjell Martin Lindberg
Lars Christer Signaes
Original Assignee
Alfa Laval Agri Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Laval Agri Int filed Critical Alfa Laval Agri Int
Application granted granted Critical
Publication of ATE125867T1 publication Critical patent/ATE125867T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90850166T 1989-05-11 1990-05-04 Fibronektinbindungsprotein und dessen herstellung. ATE125867T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8901687A SE8901687D0 (sv) 1989-05-11 1989-05-11 Fibronectin binding protein as well as its preparation

Publications (1)

Publication Number Publication Date
ATE125867T1 true ATE125867T1 (de) 1995-08-15

Family

ID=20375920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90850166T ATE125867T1 (de) 1989-05-11 1990-05-04 Fibronektinbindungsprotein und dessen herstellung.

Country Status (15)

Country Link
US (3) US5175096A (de)
EP (1) EP0397633B1 (de)
JP (1) JP3077993B2 (de)
AT (1) ATE125867T1 (de)
AU (1) AU630950B2 (de)
CA (1) CA2016521C (de)
DE (1) DE69021263T2 (de)
DK (1) DK0397633T3 (de)
ES (1) ES2077666T3 (de)
FI (1) FI102768B (de)
GR (1) GR3017946T3 (de)
IE (1) IE72968B1 (de)
NO (1) NO300069B1 (de)
NZ (1) NZ233614A (de)
SE (1) SE8901687D0 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801894D0 (sv) * 1988-05-20 1988-05-20 Alfa Laval Agri Int Fibronektinbindande protein
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
US5440014A (en) * 1990-08-10 1995-08-08 H+E,Uml/Oo/ K; Magnus Fibronectin binding peptide
US5851794A (en) * 1990-10-22 1998-12-22 Alfa Laval Ab Collagen binding protein as well as its preparation
US7279162B1 (en) 1990-10-22 2007-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated broadly reactive opsonic immunoglobulin for treating a pathogenic coagulase-negative staphylococcus infection
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5980908A (en) * 1991-12-05 1999-11-09 Alfa Laval Ab Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment
DE69434437T2 (de) * 1993-02-05 2006-04-06 Smithkline Beecham P.L.C., Brentford Fibronektinbindungsprotein, monoklonaler antikoerper und ihre verwendung zur verhuetung der adhäsion von bakterien
US5492819A (en) * 1993-09-23 1996-02-20 Genencor International, Inc. Recovery of insoluble biosynthetic products
US6033907A (en) * 1995-09-29 2000-03-07 Indiana University Foundation Enhanced virus-mediated DNA transfer
US7083979B1 (en) * 1994-03-25 2006-08-01 Indiana University Foundation Methods for enhanced retroviral-mediated gene transfer
US6933366B2 (en) * 1996-12-27 2005-08-23 Tripep Ab Specificity exchangers that redirect antibodies to bacterial adhesion receptors
US6660842B1 (en) * 1994-04-28 2003-12-09 Tripep Ab Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen
US6040137A (en) * 1995-04-27 2000-03-21 Tripep Ab Antigen/antibody specification exchanger
US20040247611A1 (en) * 1994-05-23 2004-12-09 Montana State University Identification of pathogen-ligand interactions
GB9415902D0 (en) * 1994-08-05 1994-09-28 Smithkline Beecham Plc Method of treatment
KR100506569B1 (ko) * 1995-09-29 2005-12-26 인디아나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 바이러스- 및 세포-결합 도메인을 갖는 분자를 사용하여 바이러스-매개된 dna 전달을 향상시키는 방법
GB9521146D0 (en) * 1995-10-16 1995-12-20 Smithkline Beecham Plc Novel compounds
US5858709A (en) * 1996-10-15 1999-01-12 Smithkline Beecham P.L.C. Fibronectin binding protein B compounds
US6013482A (en) 1996-10-15 2000-01-11 Smithkline Beecham Plc Cell surface protein compounds
JPH11505130A (ja) * 1995-10-16 1999-05-18 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 新規な細胞表面タンパク質化合物
US6274376B1 (en) * 1996-02-20 2001-08-14 Smithkline Beecham Corporation ClpL
US6348584B1 (en) * 1996-10-17 2002-02-19 John Edward Hodgson Fibronectin binding protein compounds
US6685943B1 (en) 1997-01-21 2004-02-03 The Texas A&M University System Fibronectin binding protein compositions and methods of use
ATE439862T1 (de) * 1997-01-21 2009-09-15 Texas A & M Univ Sys Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikírper dagegen und therapeutische anwendung
US6610293B1 (en) 1997-06-16 2003-08-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria
US6270992B1 (en) * 1997-07-29 2001-08-07 Smithkline Beecham Corporation Histidine kinase of Staphylococcus aureus
GB9720633D0 (en) * 1997-09-29 1997-11-26 Univ Bristol BHV-2 vector
US7250494B2 (en) * 1998-06-15 2007-07-31 Biosynexus Incorporated Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
US6703025B1 (en) 1998-08-31 2004-03-09 Inhibitex, Inc. Multicomponent vaccines
US20020092987A1 (en) * 1998-09-05 2002-07-18 Taehee Cho Photo detect device using quantum dots and materialization method thereof
SK782002A3 (en) 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
EP1443957A4 (de) * 2001-05-08 2005-10-12 Texas A & M Univ Sys Oberflächenproteine aus grampositiven bakterien mit hochkonservierten motiven sowie diese erkennende antikörper
US6835378B2 (en) 2001-05-11 2004-12-28 The Texas A&M University System University Method and compositions for inhibiting thrombin-induced coagulation
CA2450939C (en) 2001-06-15 2012-11-06 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus
US7115264B2 (en) * 2001-11-05 2006-10-03 Inhibitex Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections
US7335359B2 (en) 2003-02-06 2008-02-26 Tripep Ab Glycosylated specificity exchangers
EP1594898A2 (de) 2003-02-06 2005-11-16 Tripep AB Glycosylierte spezifitätaustauscher
US9296795B2 (en) * 2003-03-07 2016-03-29 Wyeth Holdings, Llc. Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
AU2004238263A1 (en) * 2003-05-06 2004-11-25 Syntonix Pharmaceuticals, Inc. Inhibition of drug binding to serum albumin
US7348004B2 (en) * 2003-05-06 2008-03-25 Syntonix Pharmaceuticals, Inc. Immunoglobulin chimeric monomer-dimer hybrids
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
PT1624891E (pt) * 2003-05-06 2010-01-05 Syntonix Pharmaceuticals Inc Proteínas quiméricas de factor de coagulação-fc destinadas ao tratamento da hemofilia
US7771731B2 (en) * 2004-05-21 2010-08-10 Wyeth Llc Altered fibronectin-binding protein of Staphylococcus aureus
JP2008513406A (ja) 2004-09-22 2008-05-01 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 免疫原性組成物
EP1998802A2 (de) 2006-03-30 2008-12-10 GlaxoSmithKline Biologicals S.A. Immunogene zusammensetzung
US20090092631A1 (en) * 2007-03-26 2009-04-09 Tripep Ab Glycosylated specificity exchangers that induce an antibody dependent cellular cytotoxicity (adcc) response
AU2008292897B2 (en) * 2007-08-31 2015-01-22 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
US8758765B2 (en) * 2008-07-29 2014-06-24 The University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
WO2010042481A1 (en) 2008-10-06 2010-04-15 University Of Chicago Compositions and methods related to bacterial eap, emp, and/or adsa proteins
PT3281947T (pt) 2009-04-03 2020-05-07 Univ Chicago Composições e métodos relacionados com variantes da proteína a (spa)
GB0913680D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
US9364516B2 (en) 2010-02-03 2016-06-14 University Of Rochester Treatment of fibrosis-related disorders using fibronectin binding proteins and polypeptides
EP2555794A4 (de) 2010-04-05 2014-01-15 Univ Chicago Zusammensetzungen und verfahren im zusammenhang mit protein-a-(spa)-antikörpern als immunreaktionsverstärker
EP2588120B1 (de) 2010-07-02 2017-11-15 The University of Chicago Zusammensetzungen und verfahren bezüglich protein-a (spa)-varianten
EP2614074A1 (de) 2010-09-09 2013-07-17 The University of Chicago Verfahren und zusammensetzungen mit schützenden staphylokokken-antigenen
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
EP2744517B1 (de) 2011-08-15 2019-03-13 The University of Chicago Zusammensetzungen und verfahren in zusammenhang mit antikörpern gegen das staphylokokken-protein a
HRP20201127T1 (hr) 2012-04-26 2020-11-27 University Of Chicago Antigeni stafilokokne koagulaze i metode primjene istih
HK1207321A1 (en) 2012-04-26 2016-01-29 University Of Chicago Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease
EA037906B1 (ru) 2013-03-15 2021-06-04 Биовератив Терапьютикс Инк. Препараты полипептида фактора ix
CN105384800B (zh) * 2015-12-07 2019-01-25 黑龙江八一农垦大学 金黄色葡萄球菌taf融合蛋白制备方法及其应用
EP3257862A1 (de) * 2016-06-16 2017-12-20 ETH Zürich Fibronectinbindende peptide zur verwendung bei der diagnose eines tumors oder von fibrose und therapie
BR112021022902A2 (pt) 2019-05-14 2022-01-25 Univ Chicago Métodos e composições que compreendem variantes de proteína a staphylococcus (spa)
WO2021051136A1 (en) 2019-09-13 2021-03-18 The University Of Chicago Methods and compositions for treating staphylococcal infections
IL291821A (en) 2019-10-02 2022-06-01 Janssen Vaccines & Prevention Bv Staphylococcus peptides and methods of use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917818A (en) * 1970-01-14 1975-11-04 Agricura Labor Ltd Treatment of mastitis in cows, the product for this treatment and to the production of said product
DE2644622C3 (de) * 1976-10-02 1979-11-29 Behringwerke Ag, 3550 Marburg Extraktion von Mikroorganismen und diese enthaltende diagnostische Mittel
SE445013B (sv) * 1979-06-21 1986-05-26 Landstingens Inkopscentral Medel for att forebygga eller behandla infektioner hos menniskor och djur
US4425330A (en) * 1981-05-20 1984-01-10 Cornell Research Foundation, Inc. Bovine mastitis vaccine and method for detecting efficacy thereof
SE446688C (sv) * 1982-09-14 1989-10-16 Magnus Hoeoek Medel foer avlaegsnande av mikroorganismer fraan vaevnader, vilket bestaar av ett protein som kan bindas till mikroorganismerna
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
US5189015A (en) * 1984-05-30 1993-02-23 Alfa-Laval Agri International Ab Method for prophylactic treatment of the colonization of a Staphylococcus aureus bacterial strain by bacterial cell surface protein with fibronectin and fibrinogen binding ability
SE454403B (sv) * 1984-05-30 1988-05-02 Alfa Laval Agri Int Anvendning av ett cellyteprotein med fibronektin-, fibrinogen-, kollagen-, och/eller lamininbindande egenskaper vid framstellning av sarbehandlingsmedel
US5320951A (en) * 1987-06-01 1994-06-14 Hoeoek Magnus Fibronectin binding protein as well as its preparation
US5571514A (en) * 1987-06-01 1996-11-05 Alfa Laval Ab Fibronectin binding protein as well as its preparation
SE8702272L (sv) * 1987-06-01 1988-12-02 Alfa Laval Agri Int Fibronektinbindande protein samt dess framstaellning
SE8801723D0 (sv) * 1988-05-06 1988-05-06 Staffan Normark Fibronectin binding protein as well as its preparation
SE8801894D0 (sv) * 1988-05-20 1988-05-20 Alfa Laval Agri Int Fibronektinbindande protein
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
SE9002617D0 (sv) * 1990-08-10 1990-08-10 Alfa Laval Agri Int A fibronectin binding peptide

Also Published As

Publication number Publication date
JPH03272687A (ja) 1991-12-04
ES2077666T3 (es) 1995-12-01
IE72968B1 (en) 1997-05-07
FI102768B1 (fi) 1999-02-15
CA2016521C (en) 2002-02-05
CA2016521A1 (en) 1990-11-11
EP0397633A2 (de) 1990-11-14
DK0397633T3 (da) 1996-01-02
AU5481890A (en) 1990-11-15
NO902082L (no) 1990-11-12
EP0397633B1 (de) 1995-08-02
US5652217A (en) 1997-07-29
NO902082D0 (no) 1990-05-10
FI902350A0 (fi) 1990-05-10
SE8901687D0 (sv) 1989-05-11
US5840846A (en) 1998-11-24
EP0397633A3 (de) 1991-07-31
NO300069B1 (no) 1997-04-01
DE69021263D1 (de) 1995-09-07
IE901696L (en) 1990-11-11
DE69021263T2 (de) 1996-01-04
AU630950B2 (en) 1992-11-12
JP3077993B2 (ja) 2000-08-21
US5175096A (en) 1992-12-29
FI102768B (fi) 1999-02-15
GR3017946T3 (en) 1996-02-29
NZ233614A (en) 1991-12-23

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Legal Events

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UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time