ATE439862T1 - Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikírper dagegen und therapeutische anwendung - Google Patents
Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikírper dagegen und therapeutische anwendungInfo
- Publication number
- ATE439862T1 ATE439862T1 AT98908439T AT98908439T ATE439862T1 AT E439862 T1 ATE439862 T1 AT E439862T1 AT 98908439 T AT98908439 T AT 98908439T AT 98908439 T AT98908439 T AT 98908439T AT E439862 T1 ATE439862 T1 AT E439862T1
- Authority
- AT
- Austria
- Prior art keywords
- fibronectin
- antibodies
- binding
- peptides
- epitopes
- Prior art date
Links
- 102000016359 Fibronectins Human genes 0.000 title abstract 5
- 108010067306 Fibronectins Proteins 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 101000815632 Streptococcus suis (strain 05ZYH33) Rqc2 homolog RqcH Proteins 0.000 title 1
- 208000034309 Bacterial disease carrier Diseases 0.000 abstract 2
- 101100227488 Staphylococcus aureus (strain USA300) fnbB gene Proteins 0.000 abstract 2
- 101150098467 fnbA gene Proteins 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108010078791 Carrier Proteins Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000191967 Staphylococcus aureus Species 0.000 abstract 1
- 241000194042 Streptococcus dysgalactiae Species 0.000 abstract 1
- 241000193996 Streptococcus pyogenes Species 0.000 abstract 1
- 102000036072 fibronectin binding proteins Human genes 0.000 abstract 1
- 108091010988 fibronectin binding proteins Proteins 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 229940115920 streptococcus dysgalactiae Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
- G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3613997P | 1997-01-21 | 1997-01-21 | |
| PCT/US1998/001222 WO1998031389A2 (en) | 1997-01-21 | 1998-01-21 | Fibronectin binding protein compositions, antibodies thereto, and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE439862T1 true ATE439862T1 (de) | 2009-09-15 |
Family
ID=21886867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98908439T ATE439862T1 (de) | 1997-01-21 | 1998-01-21 | Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikírper dagegen und therapeutische anwendung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0971740B1 (de) |
| JP (1) | JP5124062B2 (de) |
| AT (1) | ATE439862T1 (de) |
| AU (1) | AU744723B2 (de) |
| CA (1) | CA2277793A1 (de) |
| DE (1) | DE69841073D1 (de) |
| NZ (1) | NZ336781A (de) |
| WO (1) | WO1998031389A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6660842B1 (en) | 1994-04-28 | 2003-12-09 | Tripep Ab | Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen |
| US6933366B2 (en) | 1996-12-27 | 2005-08-23 | Tripep Ab | Specificity exchangers that redirect antibodies to bacterial adhesion receptors |
| EP1121149A4 (de) * | 1998-08-31 | 2002-03-20 | Inhibitex Inc | Immunotherapeutika gegen staphylokokkus mittels donor selektion und donor stimulation |
| IL141639A (en) * | 1998-08-31 | 2005-12-18 | Inhibitex Inc | Multicomponent vaccines |
| US6692739B1 (en) | 1998-08-31 | 2004-02-17 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| SE9804491D0 (sv) * | 1998-12-22 | 1998-12-22 | Bengt Guss | Novel fibronectin-binding protein |
| US7115264B2 (en) | 2001-11-05 | 2006-10-03 | Inhibitex | Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections |
| EP1594898A2 (de) | 2003-02-06 | 2005-11-16 | Tripep AB | Glycosylierte spezifitätaustauscher |
| US7335359B2 (en) | 2003-02-06 | 2008-02-26 | Tripep Ab | Glycosylated specificity exchangers |
| CN1953991A (zh) * | 2004-05-21 | 2007-04-25 | 惠氏公司 | 变异的金黄色葡萄球菌纤连蛋白结合蛋白 |
| TW200637907A (en) * | 2004-12-20 | 2006-11-01 | Scient Feed Lab Co Ltd | Novel vaccine for fish diseases against strepcococcemia |
| FR2935002B1 (fr) * | 2008-08-13 | 2014-09-05 | Biomerieux Sa | Milieu de culture permettant de differencier staphylococcus aureus des staphylococcus a coagulase negative |
| EP2561888A1 (de) * | 2011-08-23 | 2013-02-27 | Deutsches Krebsforschungszentrum | Protein enthaltend NC-1 zur Behandlung von Erkrankungen in Bezug auf Angiogenese |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8901687D0 (sv) * | 1989-05-11 | 1989-05-11 | Alfa Laval Agri Int | Fibronectin binding protein as well as its preparation |
| SE9002617D0 (sv) * | 1990-08-10 | 1990-08-10 | Alfa Laval Agri Int | A fibronectin binding peptide |
| MX9400940A (es) * | 1993-02-05 | 1994-08-31 | Smithkline Beecham Plc | Peptido d1-d4 aislado de staphylococcus aureus, anticuerpos monoclonales, procedimientos para su preparacion y composiciones farmaceuticas que los incluyen. |
| GB9415900D0 (en) * | 1994-08-05 | 1994-09-28 | Smithkline Beecham Plc | Novel compounds and treatment |
| GB9415901D0 (en) * | 1994-08-05 | 1994-09-28 | Smithkline Beecham Plc | Novel compounds and treatment |
-
1998
- 1998-01-21 DE DE69841073T patent/DE69841073D1/de not_active Expired - Lifetime
- 1998-01-21 EP EP98908439A patent/EP0971740B1/de not_active Expired - Lifetime
- 1998-01-21 NZ NZ336781A patent/NZ336781A/xx not_active IP Right Cessation
- 1998-01-21 JP JP53338298A patent/JP5124062B2/ja not_active Expired - Fee Related
- 1998-01-21 CA CA002277793A patent/CA2277793A1/en not_active Abandoned
- 1998-01-21 AU AU66479/98A patent/AU744723B2/en not_active Ceased
- 1998-01-21 WO PCT/US1998/001222 patent/WO1998031389A2/en active IP Right Grant
- 1998-01-21 AT AT98908439T patent/ATE439862T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69841073D1 (de) | 2009-10-01 |
| JP2002513398A (ja) | 2002-05-08 |
| AU744723B2 (en) | 2002-02-28 |
| NZ336781A (en) | 2002-10-25 |
| WO1998031389A2 (en) | 1998-07-23 |
| JP5124062B2 (ja) | 2013-01-23 |
| CA2277793A1 (en) | 1998-07-23 |
| AU6647998A (en) | 1998-08-07 |
| EP0971740B1 (de) | 2009-08-19 |
| WO1998031389A3 (en) | 1999-01-21 |
| EP0971740A2 (de) | 2000-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |