ATE124048T1 - Verfahren zur herstellung von beta-lactamase- inhibitoren. - Google Patents

Verfahren zur herstellung von beta-lactamase- inhibitoren.

Info

Publication number
ATE124048T1
ATE124048T1 AT90106310T AT90106310T ATE124048T1 AT E124048 T1 ATE124048 T1 AT E124048T1 AT 90106310 T AT90106310 T AT 90106310T AT 90106310 T AT90106310 T AT 90106310T AT E124048 T1 ATE124048 T1 AT E124048T1
Authority
AT
Austria
Prior art keywords
solution
lactamase inhibitors
producing beta
methoxyphenol
alpha
Prior art date
Application number
AT90106310T
Other languages
English (en)
Inventor
Raghavan Krishnan
Jesse Gamble
David Blum
William V Curran
Ving J Lee
Ransom B Conrow
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE124048T1 publication Critical patent/ATE124048T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT90106310T 1989-05-12 1990-04-02 Verfahren zur herstellung von beta-lactamase- inhibitoren. ATE124048T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/350,966 US4958020A (en) 1989-05-12 1989-05-12 Process for producing β-lactamase inhibitor

Publications (1)

Publication Number Publication Date
ATE124048T1 true ATE124048T1 (de) 1995-07-15

Family

ID=23378993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90106310T ATE124048T1 (de) 1989-05-12 1990-04-02 Verfahren zur herstellung von beta-lactamase- inhibitoren.

Country Status (10)

Country Link
US (1) US4958020A (de)
EP (1) EP0396901B1 (de)
JP (1) JP2909145B2 (de)
KR (1) KR0144453B1 (de)
AT (1) ATE124048T1 (de)
CA (1) CA2016500C (de)
DE (1) DE69020240T2 (de)
DK (1) DK0396901T3 (de)
ES (1) ES2073471T3 (de)
HU (1) HU206724B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3306473B1 (ja) * 2001-05-01 2002-07-24 大塚化学株式会社 β−ラクタム化合物の無水結晶及びその製造法
US20060173177A1 (en) * 2005-01-28 2006-08-03 Gego Csaba L Process for preparation of penam derivatives
US20070286817A1 (en) * 2006-06-07 2007-12-13 Wyeth Treating cystic fibrosis with antibiotics via a swirler delivery
US20070286818A1 (en) * 2006-06-07 2007-12-13 Wyeth Treating cystic fibrosis with antibiotics via an aerosol drug

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225091A (ja) * 1982-06-21 1983-12-27 Taiho Yakuhin Kogyo Kk ペニシリン誘導体及びその製造法
AU541028B2 (en) * 1982-06-21 1984-12-13 Taiho Pharmaceutical Co., Ltd. 6-unsubstituted penicillin derivatives
US4562073A (en) * 1982-12-24 1985-12-31 Taiho Pharmaceutical Company Limited Penicillin derivatives
US4496484A (en) * 1983-04-22 1985-01-29 Taiho Pharmaceutical Company, Limited Penicillin derivatives
CA1239392A (en) * 1983-10-13 1988-07-19 Shigeru Yamabe Penicillin derivatives and process for preparing the same
JPS61126087A (ja) * 1984-11-26 1986-06-13 Taiho Yakuhin Kogyo Kk ２α−メチル−２β−（１，２，３−トリアゾ−ル−１−イル）メチルペナム−３α−カルボン酸誘導体の製造法
JPS63112588A (ja) * 1986-10-27 1988-05-17 Denki Kagaku Kogyo Kk トリアゾ−ル誘導体の製造方法

Also Published As

Publication number Publication date
JPH02311482A (ja) 1990-12-27
DK0396901T3 (da) 1995-08-14
DE69020240D1 (de) 1995-07-27
EP0396901B1 (de) 1995-06-21
CA2016500C (en) 2000-11-28
DE69020240T2 (de) 1996-04-04
HU206724B (en) 1992-12-28
JP2909145B2 (ja) 1999-06-23
KR0144453B1 (ko) 1998-07-15
ES2073471T3 (es) 1995-08-16
HU903007D0 (en) 1990-09-28
KR900018115A (ko) 1990-12-20
CA2016500A1 (en) 1990-11-12
US4958020A (en) 1990-09-18
HUT54693A (en) 1991-03-28
EP0396901A1 (de) 1990-11-14

Similar Documents

Publication Publication Date Title
DE69126646D1 (de) Biologisches Verfahren zur Herstellung von optisch-aktiver Milchsäure
ATE124048T1 (de) Verfahren zur herstellung von beta-lactamase- inhibitoren.
ATE218131T1 (de) Verfahren zur herstellung von mono-n- substituierten tetraazamakrocyclen
ATE106887T1 (de) Ester der 10-(1-hydroxy-äthyl)-11-oxo-1- azatricyclo(7.2.0.0(3,8)>undec-2-ene-2- carbonsäure und deren derivate und verfahren zu ihrer herstellung.
DE3774954D1 (de) Verfahren zur herstellung von penemen.
ATE156133T1 (de) Verfahren zur herstellung von ph3c(b(c6f5)4>
DE69032341T2 (de) Verfahren zur Herstellung von optisch aktiven Verbindungen mit mehrfachen chiralen Mittelpunkten
ATE128457T1 (de) Optisch aktive n-aplha-fluoracryloylaminosäure- derivate, ihre herstellung, die daraus hergestellten optisch aktiven polymeren und deren verwendung zur spaltung von racematen.
DE3569725D1 (en) A method for the optical purification of an optically active 2,2-dimethylcyclopropanecarboxylic acid amide
PT70592A (de) Neue 3,4-disubstituierte 2-phenylimino-imidazolidine derensaureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
DE3864524D1 (de) Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten.
ATE215931T1 (de) Verfahren zur herstellung von 2- oxopyrrolidinylacetamid-derivaten
DE59402632D1 (de) Verfahren zur Herstellung von 3beta-Aminocholansäurederivaten
IT1197800B (it) Processo per la sintesi di acidi carbossilici
ATE182140T1 (de) Optisch aktive 1,4-dihydropyridinderivate sowie verfahren zu ihrer herstellung
ATE93832T1 (de) Verfahren zur herstellung von 4,6-dimethyl-7hydroxynonan-3-on.
ATE55769T1 (de) Substituierte dioxanone, verfahren zu deren herstellung und deren verwendung.
DE3676923D1 (de) Verfahren zur herstellung von optisch aktiven carbonylverbindungen.
ATE35676T1 (de) Verfahren zur herstellung von harnstoffacrylderivaten.
DE3851942D1 (de) Verfahren zur Herstellung von optisch aktiver alpha-Isopropyl-p-chlorophenylessigsäure.
ATA214393A (de) Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
HU914124D0 (en) Process for producing optically active quinoxalinyl-oxi-phenoxi-propionic acid esthers
DE3674122D1 (de) Verfahren zur herstellung optisch aktiver alpha-haloalkylarylketone.
DE3382080D1 (de) Verfahren zur herstellung von imidazol-verbindungen.
DE69119024T2 (de) Verfahren zur Herstellung von optisch aktiver 3-Methyladipinsäure

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time