ATE117806T1 - Bestimmungsmethode für glykosyliertes hämoglobin. - Google Patents
Bestimmungsmethode für glykosyliertes hämoglobin.Info
- Publication number
- ATE117806T1 ATE117806T1 AT90908231T AT90908231T ATE117806T1 AT E117806 T1 ATE117806 T1 AT E117806T1 AT 90908231 T AT90908231 T AT 90908231T AT 90908231 T AT90908231 T AT 90908231T AT E117806 T1 ATE117806 T1 AT E117806T1
- Authority
- AT
- Austria
- Prior art keywords
- signal
- haemoglobin
- pct
- bound
- sample
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000017011 Glycated Hemoglobin A Human genes 0.000 title 1
- 108010014663 Glycated Hemoglobin A Proteins 0.000 title 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 125000001626 borono group Chemical group [H]OB([*])O[H] 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO891929A NO891929D0 (no) | 1989-01-04 | 1989-05-11 | Nye komposisjoner med loeselige signalmolekyler for in vitro overvaaking av diabetes mellitus. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE117806T1 true ATE117806T1 (de) | 1995-02-15 |
Family
ID=19892012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90908231T ATE117806T1 (de) | 1989-05-11 | 1990-05-11 | Bestimmungsmethode für glykosyliertes hämoglobin. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5242842A (de) |
| EP (1) | EP0471774B1 (de) |
| JP (1) | JPH0812196B2 (de) |
| KR (1) | KR960010697B1 (de) |
| AT (1) | ATE117806T1 (de) |
| AU (1) | AU642879B2 (de) |
| BR (1) | BR9007357A (de) |
| CA (1) | CA2055430C (de) |
| DE (1) | DE69016423T2 (de) |
| DK (1) | DK0471774T3 (de) |
| ES (1) | ES2067029T3 (de) |
| FI (1) | FI100437B (de) |
| HU (1) | HU215181B (de) |
| NO (4) | NO890029D0 (de) |
| RU (1) | RU2111494C1 (de) |
| WO (1) | WO1990013818A1 (de) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807747A (en) * | 1989-06-13 | 1998-09-15 | Clinical Innovations Limited | Method and apparatus for determination of glycosylated protein |
| US5403745A (en) * | 1990-04-27 | 1995-04-04 | Genzyme Corporation | Determination of analytes in biological fluids in the presence of substances interfering with assays therefor |
| US5135875A (en) * | 1990-08-15 | 1992-08-04 | Abbott Laboratories | Protein precipitation reagent |
| GB9024775D0 (en) * | 1990-11-14 | 1991-01-02 | Axis Research | Chemical compounds |
| GB9024771D0 (en) * | 1990-11-14 | 1991-01-02 | Axis Research | Assay |
| DE4206932A1 (de) * | 1992-03-05 | 1993-09-09 | Boehringer Mannheim Gmbh | Immunologische methode zur bestimmung eines haemoglobinderivates |
| JP3171681B2 (ja) | 1992-08-11 | 2001-05-28 | 積水化学工業株式会社 | 糖化蛋白の測定方法 |
| US5512451A (en) * | 1993-04-01 | 1996-04-30 | British Technology Group Limited | Enhancement of chemiluminescent reactions |
| US5852178A (en) * | 1994-01-28 | 1998-12-22 | Prolinx, Inc. | Phenylboronic acid complexing reagents for conjugating biologically active molecules |
| US5623055A (en) * | 1994-01-28 | 1997-04-22 | Prolinx, Inc. | Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation |
| ATE200292T1 (de) * | 1994-01-28 | 2001-04-15 | Prolinx Inc | Phenylborsaurekomplexe |
| US5847192A (en) * | 1994-01-28 | 1998-12-08 | Prolinx, Inc. | Boronic compound complexing reagents and complexes |
| US5837878A (en) * | 1994-01-28 | 1998-11-17 | Prolinx, Inc. | Boronic compound complexing reagents and highly stable complexes |
| US5744627A (en) * | 1994-01-28 | 1998-04-28 | Prolinx, Inc. | Boronic compound complexing reagents and complexes |
| US5594151A (en) * | 1994-01-28 | 1997-01-14 | Prolinx, Inc. | Phenylboronic acid complexing reagents derived from aminosalicylic acid |
| US5777148A (en) * | 1994-01-28 | 1998-07-07 | Prolinx, Inc. | Boronic compound complexing reagents and highly stable complexes |
| US5594111A (en) * | 1994-01-28 | 1997-01-14 | Prolinx, Inc. | Phenylboronic acid complexes for bioconjugate preparation |
| US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
| GB9415143D0 (en) * | 1994-07-27 | 1994-09-14 | Edwards Raymond | Glycated haemoglobin assay |
| WO1996011398A1 (en) * | 1994-10-07 | 1996-04-18 | Merck & Co., Inc. | Process for assessing tubulin protein polymerization |
| US5695949A (en) * | 1995-04-07 | 1997-12-09 | Lxn Corp. | Combined assay for current glucose level and intermediate or long-term glycemic control |
| GB9508278D0 (en) * | 1995-04-24 | 1995-06-14 | Axis Biochemicals As | Haemoglobin standards |
| JP3269765B2 (ja) * | 1995-12-14 | 2002-04-02 | 富士写真フイルム株式会社 | ヘモグロビン誘導体の免疫学的測定方法及びその方法に用いる処理試薬 |
| US6001573A (en) * | 1996-06-14 | 1999-12-14 | Packard Bioscience B.V. | Use of porphyrins as a universal label |
| US6075126A (en) | 1996-08-05 | 2000-06-13 | Prolinx, Inc. | Phenyldiboronic acid reagents and complexes |
| US6156884A (en) | 1996-08-05 | 2000-12-05 | Prolinx, Inc. | Bifunctional boronic compound complexing reagents and complexes |
| US6316265B1 (en) | 1997-03-13 | 2001-11-13 | Abbott Laboratories | Determination of % glycated hemoglobin |
| US6162645A (en) * | 1997-03-13 | 2000-12-19 | Abbott Laboratories | Determination of % glycated hemoglobin |
| DE19843094A1 (de) | 1998-09-21 | 2000-03-23 | Roche Diagnostics Gmbh | Verfahren zur Bestimmung von glykiertem Hämoglobin |
| DE19856433C2 (de) * | 1998-12-08 | 2001-09-13 | Aventis Behring Gmbh | Verfahren zum spezifischen Nachweis von glykosilierten Proteinen |
| RU2159442C1 (ru) * | 1999-11-23 | 2000-11-20 | Закрытое акционерное общество "Вектор-Бест" | Набор реагентов для определения концентрации гемоглобина в крови |
| US7470420B2 (en) * | 2000-12-05 | 2008-12-30 | The Regents Of The University Of California | Optical determination of glucose utilizing boronic acid adducts |
| US6653141B2 (en) | 2000-12-05 | 2003-11-25 | The Regents Of The University Of California | Polyhydroxyl-substituted organic molecule sensing method and device |
| US6627177B2 (en) | 2000-12-05 | 2003-09-30 | The Regents Of The University Of California | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof |
| US7195923B2 (en) * | 2001-01-31 | 2007-03-27 | Scripps Laboratories, Inc. | Ratiometric determination of glycated protein |
| GB0110053D0 (en) * | 2001-04-24 | 2001-06-13 | Axis Shield Asa | Assay |
| US6852503B1 (en) * | 2001-05-30 | 2005-02-08 | Pierce Biotechnology, Inc. | Compositions and methods for utilizing mixed substrate solutions of luminols and dioxetanes |
| WO2004042364A2 (en) * | 2002-11-05 | 2004-05-21 | Therasense, Inc. | Assay device, system and method |
| RU2234703C1 (ru) * | 2002-12-18 | 2004-08-20 | Мищенко Борис Петрович | Способ количественного определения гликогемоглобина |
| US7390670B2 (en) * | 2003-02-20 | 2008-06-24 | Lumigen, Inc. | Signalling compounds and methods for detecting hydrogen peroxide |
| AU2005203321A1 (en) * | 2004-08-03 | 2006-02-23 | Axis-Shield Diagnostics Limited | Assay |
| US20110136157A1 (en) * | 2005-04-25 | 2011-06-09 | Garth James Smith Cooper | Copper regulation evaluation and therapy |
| GB2436681B (en) * | 2006-03-31 | 2010-10-13 | Quotient Diagnostics Ltd | Fluorescent assay |
| US20100012049A1 (en) * | 2006-04-12 | 2010-01-21 | Jms Co., Ltd | Cavitation heating system and method |
| US8338183B2 (en) * | 2006-07-29 | 2012-12-25 | I-Sens, Inc. | Electrochemical determination system of glycated proteins |
| RU2378315C1 (ru) * | 2008-04-17 | 2010-01-10 | Закрытое акционерное общество "ДиаМорф" | Полифункциональная хемилюминесцентная композиция |
| KR101005559B1 (ko) | 2008-07-15 | 2011-01-05 | 주식회사 아이센스 | 바이오센서를 이용한 단백질 측정 장치 |
| BRPI0914373A2 (pt) * | 2008-10-14 | 2015-10-20 | Piramal Healthcare Ltd | "método eletroquímico não-enzimático para determinação simultânea de hemoglobina total e hemoglibina glicosilada" |
| EP2444803A4 (de) | 2009-06-19 | 2012-11-14 | Infopia Co Ltd | Verfahren zur messung von glykiertem hämoglobin |
| CN104053992B (zh) * | 2012-01-16 | 2016-12-14 | 皇家飞利浦有限公司 | 确定包括细胞的体液中的靶分子的存在 |
| GB201215571D0 (en) | 2012-08-31 | 2012-10-17 | Axis Shield Asa | Assay method |
| KR20140032221A (ko) * | 2012-09-06 | 2014-03-14 | 삼성전자주식회사 | 시료 중의 당화 단백질을 확인하는 방법 및 그를 위한 장치 |
| RU2612092C1 (ru) * | 2015-12-08 | 2017-03-02 | Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения Российской Федерации (ФГБУ "РКНПК" Минздрава России) | Способ диагностики сахарного диабета по уровню метилглиоксаль-модифицированных липопротеидов низкой плотности с использованием моноклональных антител |
| CN107153121B (zh) * | 2017-04-12 | 2019-03-08 | 深圳市东邦生物医疗技术有限公司 | 糖化血红蛋白、血红蛋白检测试剂盒及其检测方法 |
| CN115825293B (zh) * | 2023-02-21 | 2023-10-13 | 艾康生物技术(杭州)有限公司 | 一种用于糖化血红蛋白测试的试剂盒 |
| CN119804843A (zh) * | 2024-12-31 | 2025-04-11 | 深圳市新产业生物医学工程股份有限公司 | 全血样本中待测物的免疫学检测方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4269605A (en) * | 1978-06-28 | 1981-05-26 | Amicon Corporation | Method and kit for separation of glycoproteins |
| US4268270A (en) * | 1979-04-30 | 1981-05-19 | Children's Hospital Medical Center | Glycosylated hemoglobin measurement |
| FR2464475A1 (fr) * | 1979-08-30 | 1981-03-06 | Amicon Corp | Procede et produit pour la separation des glycoproteines et leur application notamment a la determination de l'hemoglobine glycosylee |
| JPS5640694A (en) * | 1979-09-06 | 1981-04-16 | Amicon Corp | Method of separating glycoprotein and chemical agent therefor |
| US4371374A (en) * | 1980-11-17 | 1983-02-01 | The Rockefeller University | Monitoring metabolic control in diabetic patients by measuring glycosylated amino acids and peptides in urine |
| US4407961A (en) * | 1981-03-16 | 1983-10-04 | Sanders James L | Ion-exchange system and method for isolation and determination of glycosylated hemoglobin in human blood |
| US4659817A (en) * | 1981-05-01 | 1987-04-21 | The Children's Medical Center Corporation | Reporter compounds containing boron |
| GB8504521D0 (en) * | 1985-02-21 | 1985-03-27 | Genetics Int Inc | Electrochemical assay |
| US4861728A (en) * | 1987-07-24 | 1989-08-29 | Becton, Dickinson And Company | Immunoassay of glycosylated hemoglobin using a labeled boron reagent |
| US5137833A (en) * | 1989-09-21 | 1992-08-11 | Russell Anthony P | Method for detecting polyhydroxyl compounds |
-
1989
- 1989-01-04 NO NO890029A patent/NO890029D0/no unknown
- 1989-05-11 NO NO891929A patent/NO891929D0/no unknown
-
1990
- 1990-04-11 NO NO901643A patent/NO901643D0/no unknown
- 1990-05-11 AT AT90908231T patent/ATE117806T1/de not_active IP Right Cessation
- 1990-05-11 BR BR909007357A patent/BR9007357A/pt not_active IP Right Cessation
- 1990-05-11 DK DK90908231.5T patent/DK0471774T3/da active
- 1990-05-11 CA CA002055430A patent/CA2055430C/en not_active Expired - Fee Related
- 1990-05-11 RU SU5010459A patent/RU2111494C1/ru not_active IP Right Cessation
- 1990-05-11 EP EP90908231A patent/EP0471774B1/de not_active Expired - Lifetime
- 1990-05-11 HU HU904320A patent/HU215181B/hu not_active IP Right Cessation
- 1990-05-11 WO PCT/EP1990/000820 patent/WO1990013818A1/en not_active Ceased
- 1990-05-11 AU AU56670/90A patent/AU642879B2/en not_active Ceased
- 1990-05-11 DE DE69016423T patent/DE69016423T2/de not_active Expired - Fee Related
- 1990-05-11 US US07/613,505 patent/US5242842A/en not_active Expired - Lifetime
- 1990-05-11 KR KR1019910701571A patent/KR960010697B1/ko not_active Expired - Fee Related
- 1990-05-11 ES ES90908231T patent/ES2067029T3/es not_active Expired - Lifetime
- 1990-05-11 JP JP2507703A patent/JPH0812196B2/ja not_active Expired - Lifetime
-
1991
- 1991-11-08 NO NO914372A patent/NO302784B1/no unknown
- 1991-11-08 FI FI915284A patent/FI100437B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| HUT66835A (en) | 1995-01-30 |
| DE69016423T2 (de) | 1995-06-14 |
| JPH04506703A (ja) | 1992-11-19 |
| WO1990013818A1 (en) | 1990-11-15 |
| HU904320D0 (en) | 1992-02-28 |
| AU642879B2 (en) | 1993-11-04 |
| NO891929D0 (no) | 1989-05-11 |
| NO890029D0 (no) | 1989-01-04 |
| DE69016423D1 (de) | 1995-03-09 |
| CA2055430A1 (en) | 1990-11-12 |
| NO302784B1 (no) | 1998-04-20 |
| DK0471774T3 (da) | 1995-03-20 |
| BR9007357A (pt) | 1992-04-21 |
| US5242842A (en) | 1993-09-07 |
| NO901643D0 (no) | 1990-04-11 |
| EP0471774B1 (de) | 1995-01-25 |
| AU5667090A (en) | 1990-11-29 |
| KR920701824A (ko) | 1992-08-12 |
| RU2111494C1 (ru) | 1998-05-20 |
| CA2055430C (en) | 1999-08-31 |
| HU215181B (hu) | 1998-10-28 |
| KR960010697B1 (ko) | 1996-08-07 |
| JPH0812196B2 (ja) | 1996-02-07 |
| FI915284A0 (fi) | 1991-11-08 |
| EP0471774A1 (de) | 1992-02-26 |
| NO914372L (no) | 1992-01-09 |
| ES2067029T3 (es) | 1995-03-16 |
| NO914372D0 (no) | 1991-11-08 |
| FI100437B (fi) | 1997-11-28 |
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