ATE115550T1 - Glutamin- und asparginsäurederivate mit antigastrinwirkung und verfahren zu deren herstellung. - Google Patents

Glutamin- und asparginsäurederivate mit antigastrinwirkung und verfahren zu deren herstellung.

Info

Publication number
ATE115550T1
ATE115550T1 AT90916273T AT90916273T ATE115550T1 AT E115550 T1 ATE115550 T1 AT E115550T1 AT 90916273 T AT90916273 T AT 90916273T AT 90916273 T AT90916273 T AT 90916273T AT E115550 T1 ATE115550 T1 AT E115550T1
Authority
AT
Austria
Prior art keywords
antigastrin
aspartic acid
acid derivatives
group
glutaminic
Prior art date
Application number
AT90916273T
Other languages
English (en)
Inventor
Francesco Makovec
Claudio Lucio Rovati
Angelo Luigi Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Application granted granted Critical
Publication of ATE115550T1 publication Critical patent/ATE115550T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT90916273T 1989-11-02 1990-10-25 Glutamin- und asparginsäurederivate mit antigastrinwirkung und verfahren zu deren herstellung. ATE115550T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT67937A IT1238664B (it) 1989-11-02 1989-11-02 Derivati degli acidi glutammico ed aspartico ad attivita' antigastrinica e procedimento per la loro preparazione

Publications (1)

Publication Number Publication Date
ATE115550T1 true ATE115550T1 (de) 1994-12-15

Family

ID=11306521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90916273T ATE115550T1 (de) 1989-11-02 1990-10-25 Glutamin- und asparginsäurederivate mit antigastrinwirkung und verfahren zu deren herstellung.

Country Status (10)

Country Link
EP (1) EP0498830B1 (de)
JP (1) JPH05501411A (de)
AT (1) ATE115550T1 (de)
AU (1) AU6637690A (de)
CA (1) CA2067569A1 (de)
DE (1) DE69015208T2 (de)
ES (1) ES2066232T3 (de)
IT (1) IT1238664B (de)
PT (1) PT95766A (de)
WO (1) WO1991006529A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241029B (it) * 1990-12-11 1993-12-27 Rotta Research Lab Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione
IT1263116B (it) * 1992-04-09 1996-07-30 Rotta Research Lab Derivati basici dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso farmaceutico
WO1997044341A1 (en) * 1996-05-17 1997-11-27 Rotta Research Laboratorium S.P.A. Cyclic polyamides of glutamic acid and aspartic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use
WO1997045415A1 (en) * 1996-05-28 1997-12-04 Rotta Research Laboratorium S.P.A. Polyamide derivatives or ornithine, lysine and analogous substances with cck-b and gastrin-antagonistic activity

Also Published As

Publication number Publication date
IT1238664B (it) 1993-09-01
WO1991006529A1 (en) 1991-05-16
IT8967937A1 (it) 1991-05-02
IT8967937A0 (it) 1989-11-02
EP0498830A1 (de) 1992-08-19
CA2067569A1 (en) 1991-05-03
ES2066232T3 (es) 1995-03-01
AU6637690A (en) 1991-05-31
PT95766A (pt) 1991-09-13
DE69015208D1 (de) 1995-01-26
JPH05501411A (ja) 1993-03-18
DE69015208T2 (de) 1995-05-04
EP0498830B1 (de) 1994-12-14

Similar Documents

Publication Publication Date Title
DK0447285T3 (da) Nephtalenderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem
DK116480A (da) Fremgangsmaade til fremstilling af substituerede chromoner
FI893467A (fi) Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
PT98959A (pt) Processo de preparacao de compostos 6- ou 7-(2-imino-2-imidazolidina)-1,4-benzoxazinas e de composicoes farmaceuticas que os contem
IT1153216B (it) Procedimento per la preparazione di composti cianoeterociclici
ES8606336A1 (es) Un procedimiento para la preparacion de derivados de tiazol 2,4-disustituidos
ATE28565T1 (de) Spiro(4.(3+n))-2-aza-alkan-3-carbonsaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung.
PT71644B (de) Verfahren zur herstellung von 4-phenoxypiperidinen
PT97700A (pt) Processo de preparacao de agentes terapeuticos anti-diabeticos
ATE115550T1 (de) Glutamin- und asparginsäurederivate mit antigastrinwirkung und verfahren zu deren herstellung.
ATE48276T1 (de) 1,6-naphthyridin-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel.
ATE123283T1 (de) Indolderivate, herstellung und verwendung.
ATE6500T1 (de) 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3 4-tetrahydronaphthalin, seine salze, und verfahren zu dessen herstellung.
KR910006292A (ko) 방향족 산의 n-아자비시클로 [3.3.0] 옥탄 아미드
HUT53638A (en) Process for producing 15-amino-substituted 20,21-dinoreburnamenie derivatives and pharmaceutical compositions containing them
ATE165829T1 (de) Nootrope wirkstoffe
TH22634A (th) " เบนซอกซาโซลิล และเบนโซไธอะโซลิลออกซาโซลิดิโนน "
TH13340A (th) 2 , 3 - ไดดีออกซี - 5 - ไตรฟลูออโรเมทธิลยุรีตีนที่ถูกแทนที่ ขบวนการเตรียมและการใช้ในเภสัชภัณฑ์
DE69116680D1 (de) Imidazol-2-yl-derivate von bicyclischen verbindungen und verfahren zu deren herstellung
TH1593A (th) แอลฟา-แอลคิล โพลิโอลีฟินิค คาร์บอกซิลิคแอซิด และอนุพันธ์ของสารนั้น ซึ่งใช้เป็นประโยชน์ในการรักษาโรคขี้เรื้อนกวาง
ES433899A1 (es) Procedimiento para la preparacion de nuevas bencilaminas.
MY101827A (en) 2-[n-substitutedguanidino]-4-heteroarylthiazole antiulcer agents
TH1594A (th) สารประกอบไทรไซคลิค
LV10711A (lv) Akrilskabes amida atvasinajumu iegusanas panemiens jaunie akrilskabes amida atvasinajumi farmaceitiskas kompozicijas kas satur sos savienojumus un to pielietojums medicina

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee