DK116480A - Fremgangsmaade til fremstilling af substituerede chromoner - Google Patents

Fremgangsmaade til fremstilling af substituerede chromoner

Info

Publication number
DK116480A
DK116480A DK116480A DK116480A DK116480A DK 116480 A DK116480 A DK 116480A DK 116480 A DK116480 A DK 116480A DK 116480 A DK116480 A DK 116480A DK 116480 A DK116480 A DK 116480A
Authority
DK
Denmark
Prior art keywords
carbon atoms
compounds
tetrazolyl
alkoxy
procedure
Prior art date
Application number
DK116480A
Other languages
English (en)
Inventor
T R Chamberlein
J R Bantick
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of DK116480A publication Critical patent/DK116480A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • C07D303/26—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds having one or more free hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK116480A 1979-03-20 1980-03-18 Fremgangsmaade til fremstilling af substituerede chromoner DK116480A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7909835 1979-03-20

Publications (1)

Publication Number Publication Date
DK116480A true DK116480A (da) 1980-09-21

Family

ID=10504010

Family Applications (1)

Application Number Title Priority Date Filing Date
DK116480A DK116480A (da) 1979-03-20 1980-03-18 Fremgangsmaade til fremstilling af substituerede chromoner

Country Status (11)

Country Link
US (1) US4281008A (da)
EP (1) EP0017332B1 (da)
JP (1) JPS55127384A (da)
AT (1) ATE14579T1 (da)
AU (1) AU515774B2 (da)
DE (1) DE3070912D1 (da)
DK (1) DK116480A (da)
FI (1) FI800823A (da)
IE (1) IE50377B1 (da)
NO (1) NO800796L (da)
ZA (1) ZA801543B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474788A (en) * 1981-11-12 1984-10-02 Fisons Plc Anti-SRSA quinoline carboxylic acid derivatives
US4788214A (en) * 1983-06-24 1988-11-29 Hoffman-La Roche Inc. 3,4-dihydro-2H-1-benzopyran derivatives
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
AU548450B2 (en) * 1983-08-08 1985-12-12 G.D. Searle & Co. Substituted dihydrobenzopyrans
US4778903A (en) * 1983-12-12 1988-10-18 G. D. Searle & Co. Substituted dihydrobenzopyrans
US4665203A (en) * 1983-08-08 1987-05-12 G. D. Searle & Co. Substituted dihydrobenzopyrans useful as leukotriene D4 inhibitors
US4888356A (en) * 1983-08-08 1989-12-19 G. D. Searle And Company Use of substituted dihydrobenzopyrans for allergy and inflammation
US4565882A (en) * 1984-01-06 1986-01-21 G. D. Searle & Co. Substituted dihydrobenzopyran-2-carboxylates
US4546194A (en) * 1984-05-29 1985-10-08 G. D. Searle & Co. Substituted chromanon-2-yl alkanols and derivatives thereof
US4935529A (en) * 1986-01-31 1990-06-19 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Cytoxic substances from the marine cyanophyte hormothamnion enteromorphoides grunow
US4801616A (en) * 1986-03-25 1989-01-31 Eli Lilly And Company Diphenylmethanone compounds and anti-inflammatory use thereof
US4874777A (en) * 1987-04-10 1989-10-17 Eli Lilly And Company Leukotriene antagonists
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
US4889871A (en) * 1987-05-29 1989-12-26 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
IL89713A0 (en) * 1988-03-29 1989-09-28 Ciba Geigy Ag Novel alkanophenones
US5149717A (en) * 1988-03-29 1992-09-22 Ciba-Geigy Corporation Alkanophenones useful for treating allergies
US5093353A (en) * 1988-05-20 1992-03-03 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US5219883A (en) * 1988-05-20 1993-06-15 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US4950684A (en) * 1988-05-20 1990-08-21 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US5073562A (en) * 1990-05-10 1991-12-17 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
US5192782A (en) * 1990-05-10 1993-03-09 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
US5212198A (en) * 1990-05-10 1993-05-18 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
US5124350A (en) * 1990-06-28 1992-06-23 G. D. Searle & Co. Leukotriene b4 antagonists
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
US5380740A (en) * 1993-04-28 1995-01-10 G. D. Searle & Co. Anti-inflammatory compounds, compositions and method of use thereof
US5457124A (en) * 1993-12-07 1995-10-10 Hoffmann-La Roche Inc. Carboxylic acid Leukotriene B4 antagonists
JPH08311032A (ja) * 1995-05-18 1996-11-26 Eisai Co Ltd α，β−不飽和ケトン誘導体
IT1303688B1 (it) * 1998-11-02 2001-02-23 Medidom Lab Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors
CN114437011B (zh) * 2022-01-06 2023-11-03 中南民族大学 一种色原酮类化合物及其制备方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133889A (en) * 1971-07-29 1979-01-09 Fisons, Ltd. 2(5-Tetrazolyl)chromones
JPS5118955B2 (da) * 1972-04-12 1976-06-14
GB1484134A (en) * 1973-11-21 1977-08-24 Fisons Ltd Benzopyran derivatives processes for their preparation and compositions containing them
US4018798A (en) * 1975-11-20 1977-04-19 Warner-Lambert Company Substituted (4-oxo-4H-1-benzopyran-2-yl)cyclopropane carboxylic acids and esters
US4033845A (en) * 1975-11-20 1977-07-05 Warner-Lambert Company [2-(4-Oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitriles and benzoic acids

Also Published As

Publication number Publication date
FI800823A (fi) 1980-09-21
EP0017332A1 (en) 1980-10-15
NO800796L (no) 1980-09-22
US4281008A (en) 1981-07-28
IE50377B1 (en) 1986-04-16
ZA801543B (en) 1981-03-25
JPS55127384A (en) 1980-10-02
IE800559L (en) 1980-09-20
ATE14579T1 (de) 1985-08-15
EP0017332B1 (en) 1985-07-31
AU515774B2 (en) 1981-04-30
AU5651680A (en) 1980-09-25
DE3070912D1 (en) 1985-09-05

Similar Documents

Publication Publication Date Title
DK116480A (da) Fremgangsmaade til fremstilling af substituerede chromoner
ATE25251T1 (de) Anti srs-a carbonsaeure-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische formulierungen.
DK160877C (da) Fremgangsmaade til fremstilling af 2-penemforbindelser
ES2059069T3 (es) Nuevos derivados de 1-alcoxi-(2-acilamino-etil)-naftalenos y su procedimiento de preparacion.
ES520987A0 (es) Procedimiento para la preparacion de derivados de acido espiro (4.(3+n))-2-aza-3carboxilico.
DE3062609D1 (en) Muramyldipeptide derivatives, process for preparing said compounds and pharmaceutical compositions containing said compounds
ES484059A1 (es) Procedimiento para proteger materiales queratinicos contra el ataque de insectos devoradores de queratina
ES547306A0 (es) Procedimiento para la produccion de derivados de quinolina.
PT89082A (pt) Processo para a preparacao de novos derivados n-(23-vinblastinoilicos)do acido 1-amino-metilfosfonico
FI854596A (fi) Nytt foerfarande foer uppdelning av racemiska -naftylpropionsyror i optiska isomerer.
EA200001107A1 (ru) ПРОИЗВОДНЫЕ ОКТАГИДРО-6,10-ДИОКСО-6H-ПИРИДАЗИНО [1,2-a] [1,2] ДИАЗЕПИН-1-КАРБОНОВОЙ КИСЛОТЫ, СПОСОБ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ ДЛЯ ПОЛУЧЕНИЯ ТЕРАПЕВТИЧЕСКИ АКТИВНЫХ СОЕДИНЕНИЙ
ZA807337B (en) 2-phenylamino-imidazolines-(2),processes for their preparation,and pharmaceutical compositions thereof
ES8200648A2 (es) Procedimiento de preparacion de compuestos opacificantes para radiografia y similares
DK601883D0 (da) Phenyl-propanolderivater
SE7902665L (sv) 5-substituerade pikolinsyraderivat, forfarande for framstellning derav och en antihypertensiv komposition innehallande dessa
GB2022583A (en) New ionic polyiodo benzene derivatives useful as X-ray contrast media

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment