ATE115403T1 - Aus phospholipiden bestehende darreichungsform für wasserunlösliche wirksubstanzen. - Google Patents

Aus phospholipiden bestehende darreichungsform für wasserunlösliche wirksubstanzen.

Info

Publication number
ATE115403T1
ATE115403T1 AT88300529T AT88300529T ATE115403T1 AT E115403 T1 ATE115403 T1 AT E115403T1 AT 88300529 T AT88300529 T AT 88300529T AT 88300529 T AT88300529 T AT 88300529T AT E115403 T1 ATE115403 T1 AT E115403T1
Authority
AT
Austria
Prior art keywords
phospholipids
triglyceride
water
dosage form
active ingredient
Prior art date
Application number
AT88300529T
Other languages
English (en)
Inventor
Eric Anton Forssen
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21725588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE115403(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vestar Inc filed Critical Vestar Inc
Application granted granted Critical
Publication of ATE115403T1 publication Critical patent/ATE115403T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
AT88300529T 1987-01-27 1988-01-22 Aus phospholipiden bestehende darreichungsform für wasserunlösliche wirksubstanzen. ATE115403T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US733887A 1987-01-27 1987-01-27

Publications (1)

Publication Number Publication Date
ATE115403T1 true ATE115403T1 (de) 1994-12-15

Family

ID=21725588

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88300529T ATE115403T1 (de) 1987-01-27 1988-01-22 Aus phospholipiden bestehende darreichungsform für wasserunlösliche wirksubstanzen.

Country Status (13)

Country Link
US (1) US4963363A (de)
EP (1) EP0280394B1 (de)
JP (1) JP2677576B2 (de)
KR (1) KR960009181B1 (de)
AT (1) ATE115403T1 (de)
AU (1) AU604288B2 (de)
CA (1) CA1314213C (de)
DE (1) DE3852409T2 (de)
DK (1) DK32388A (de)
ES (1) ES2068197T3 (de)
GR (1) GR3015290T3 (de)
IE (1) IE65987B1 (de)
NO (1) NO177774C (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03128321A (ja) * 1989-06-12 1991-05-31 Res Inst For Prod Dev 人工酸素運搬体
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
US5221535A (en) * 1989-11-13 1993-06-22 Nova Pharmaceutical Corporation Sustained release formulations of insect repellent
IE904098A1 (en) * 1989-11-13 1991-05-22 Nova Pharm Corp Lipospheres for controlled delivery of substances
US5665379A (en) * 1990-09-28 1997-09-09 Pharmacia & Upjohn Aktiebolag Lipid particle forming matrix, preparation and use thereof
SE9003100D0 (sv) * 1990-09-28 1990-09-28 Kabivitrum Ab Lipid formulation system
SE9200951D0 (sv) * 1992-03-27 1992-03-27 Kabi Pharmacia Ab Pharmaceutical composition containing a defined lipid system
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas
US5885486A (en) * 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5714163A (en) * 1994-06-27 1998-02-03 Nexstar Pharmaceuticals, Inc. Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties
US6120800A (en) * 1997-09-25 2000-09-19 Nexstar Pharmaceuticals, Inc. Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties
TWI241915B (en) 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
AU2002342018A1 (en) * 2001-10-12 2003-04-28 New York University Trisubstituted triazines compounds with antitubulin activity
US7592451B2 (en) * 2005-06-23 2009-09-22 New York University Treatment for diabetes and obesity as well as method of screening compounds useful for such treatments
JP6661319B2 (ja) * 2015-09-28 2020-03-11 小林製薬株式会社 リポソーム

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957971A (en) * 1974-07-29 1976-05-18 Lever Brothers Company Moisturizing units and moisturizing compositions containing the same
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
CA1119955A (en) * 1978-04-14 1982-03-16 Little (Arthur D.), Inc. Xenobiotic delivery vehicles, method of forming them and method of using them
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
JPS6348214A (ja) * 1986-08-18 1988-02-29 Morishita Seiyaku Kk １−〔２−（２，４−ジクロロフエニル）−３−メチル−１−ペンテニル〕−１ｈ−イミダゾ−ルを含有する水中油型脂肪乳剤

Also Published As

Publication number Publication date
DK32388A (da) 1988-07-28
NO177774C (no) 1995-11-22
DE3852409T2 (de) 1995-04-20
JPS63246320A (ja) 1988-10-13
JP2677576B2 (ja) 1997-11-17
KR880008802A (ko) 1988-09-13
IE65987B1 (en) 1995-11-29
NO880272L (no) 1988-07-27
KR960009181B1 (ko) 1996-07-16
IE880179L (en) 1988-07-27
US4963363A (en) 1990-10-16
NO880272D0 (no) 1988-01-22
DE3852409D1 (de) 1995-01-26
AU1073688A (en) 1988-07-28
AU604288B2 (en) 1990-12-13
NO177774B (no) 1995-08-14
EP0280394B1 (de) 1994-12-14
ES2068197T3 (es) 1995-04-16
GR3015290T3 (en) 1995-06-30
CA1314213C (en) 1993-03-09
DK32388D0 (da) 1988-01-25
EP0280394A1 (de) 1988-08-31

Similar Documents

Publication Publication Date Title
DE3852409D1 (de) Aus Phospholipiden bestehende Darreichungsform für wasserunlösliche Wirksubstanzen.
HUT50794A (en) Herbicides comprising substituted benztriazole derivatives as active ingredient and process for producing the active ingredients
ES8607906A1 (es) Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares
EP0219922A3 (en) Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
EP0153364A4 (de) Verbesserung der antimikrobiellen wirkung durch verbindung eines gemisches von antimikrobiellen agenzien in lipidbläschen.
HUT45850A (en) Insecticides comprising azolinone derivatives as active ingredient and process for producing the active ingredients
HUT47383A (en) Fungicides and insecticides comprising 2-anilino-pyrimidine derivatives as active ingredient and process for producing the active ingredients
IT8521603A0 (it) Composizioni farmaceutiche contenenti come principi attivi flavanolignani e fosfolipidi.
HUT47392A (en) Insecticides comprising condensed heterocyclic compounds substituted with nitro group as active ingredient and process for producing the active ingredients
CA2117769A1 (en) Liposome composition
HUT41957A (en) Insecticide compositions containing aryl-pyridon derivatives as active agents and process for producing the active agents
HUT41365A (en) Insecticide compositions containing substituted benzyl-ether derivatives as active ingredients and process for preparing the active substances
PT83184A (en) Process for the preparation of 1-arylpyrazoles with actions for combating pests in particular as insecticides and acaricides
HUT41605A (en) Insecticide compositions containing piridazinone derivatives as active ingredients and process for preparing the active substances
HUT41213A (en) Pesticide compositions containing benzodioxole derivatives as active ingredients and process for preparing the active compounds
HUT49875A (en) Herbicides comprising substituted sulfonylaminoazole derivatives as active ingredient and process for producing the active ingredients
HUT48217A (en) Pesticides comprising 5-methylamino-1-arylpyrazole derivatives as active ingredient and process for producing the active ingredients
HUT39569A (en) Pesticide compositions containing 13beta-milbemycin derivatives and process for preparing the active ingredients
HUT39957A (en) Insecticide and acaricide compositions and process for preparing the active ingredients
FI896086A0 (fi) Menetelmä 2,4-di-t-butyylifenolin fosforiorgaanisten johdannaisten, bifenyylin 4,4'-dihalogeenimagnesium-yhdisteiden valmistamiseksi ja fosforiorgaanisten johdannaisten käyttö tekoaineiden, erityisesti polyolefiini-muovausmassojen stabilointiin
HUT51105A (en) Pesticide comprising substituted acrylic acid ester derivatives as active ingredient and process for producing the active ingredients
HUT41376A (en) Insecticide compositions containing phenyl-hidrazine derivatives as active agents and process for producing the active agents
HUT41211A (en) Insecticide compositions containing alkane derivatives as active substances and process for preparing the active ingredients
HUT40556A (en) Insecticide composition containing oxim-ether derivatives as active agents and process for producing the active agents
HUT47397A (en) Herbicides comprising sulfonyl-amino-guanidino-azine derivatives as active ingredient and process for producing the active ingredients

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee