ATE112278T1 - 1,2,3,3a,8,8a-hexahydro-1,3a,8- trimethylpyrrolo(2,3-b>indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents

1,2,3,3a,8,8a-hexahydro-1,3a,8- trimethylpyrrolo(2,3-b>indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.

Info

Publication number
ATE112278T1
ATE112278T1 AT87110184T AT87110184T ATE112278T1 AT E112278 T1 ATE112278 T1 AT E112278T1 AT 87110184 T AT87110184 T AT 87110184T AT 87110184 T AT87110184 T AT 87110184T AT E112278 T1 ATE112278 T1 AT E112278T1
Authority
AT
Austria
Prior art keywords
loweralkyl
methyl
hydrogen
arylloweralkyl
trimethylpyrrolo
Prior art date
Application number
AT87110184T
Other languages
English (en)
Inventor
Russel Richard Lee Hamer
Grover Cleveland Helsley
Edward J Glamkowski
Yulin Chiang
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of ATE112278T1 publication Critical patent/ATE112278T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT87110184T 1986-07-16 1987-07-15 1,2,3,3a,8,8a-hexahydro-1,3a,8- trimethylpyrrolo(2,3-b>indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. ATE112278T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88599186A 1986-07-16 1986-07-16
US07/049,894 US4791107A (en) 1986-07-16 1987-05-15 Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use

Publications (1)

Publication Number Publication Date
ATE112278T1 true ATE112278T1 (de) 1994-10-15

Family

ID=26727666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87110184T ATE112278T1 (de) 1986-07-16 1987-07-15 1,2,3,3a,8,8a-hexahydro-1,3a,8- trimethylpyrrolo(2,3-b>indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.

Country Status (15)

Country Link
US (9) US4791107A (de)
EP (1) EP0253372B1 (de)
JP (1) JP2716099B2 (de)
KR (1) KR960003614B1 (de)
AT (1) ATE112278T1 (de)
AU (1) AU612583B2 (de)
CA (1) CA1307788C (de)
DE (1) DE3750596T2 (de)
DK (1) DK367987A (de)
ES (1) ES2060585T3 (de)
HU (1) HU206717B (de)
IE (1) IE64429B1 (de)
IL (1) IL83190A0 (de)
NZ (1) NZ221060A (de)
PT (1) PT85334B (de)

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Also Published As

Publication number Publication date
JP2716099B2 (ja) 1998-02-18
AU612583B2 (en) 1991-07-18
US5550253A (en) 1996-08-27
EP0253372A2 (de) 1988-01-20
US5639892A (en) 1997-06-17
DE3750596T2 (de) 1995-03-23
US5547977A (en) 1996-08-20
US5541340A (en) 1996-07-30
JPS6323881A (ja) 1988-02-01
DK367987D0 (da) 1987-07-15
PT85334B (pt) 1990-04-30
HUT47275A (en) 1989-02-28
HU206717B (en) 1992-12-28
EP0253372A3 (en) 1989-11-08
CA1307788C (en) 1992-09-22
US5621114A (en) 1997-04-15
US4791107A (en) 1988-12-13
US5550254A (en) 1996-08-27
AU7566887A (en) 1988-01-21
DE3750596D1 (de) 1994-11-03
IE871911L (en) 1988-01-16
EP0253372B1 (de) 1994-09-28
US5663190A (en) 1997-09-02
ES2060585T3 (es) 1994-12-01
PT85334A (en) 1987-08-01
KR880001656A (ko) 1988-04-25
DK367987A (da) 1988-01-17
US5541216A (en) 1996-07-30
IE64429B1 (en) 1995-08-09
KR960003614B1 (ko) 1996-03-20
NZ221060A (en) 1990-11-27
IL83190A0 (en) 1987-12-31

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