IT1109003B - Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo - Google Patents

Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo

Info

Publication number
IT1109003B
IT1109003B IT09574/77A IT957477A IT1109003B IT 1109003 B IT1109003 B IT 1109003B IT 09574/77 A IT09574/77 A IT 09574/77A IT 957477 A IT957477 A IT 957477A IT 1109003 B IT1109003 B IT 1109003B
Authority
IT
Italy
Prior art keywords
dropirrolo
esai
indolo
derivatives
esai dropirrolo
Prior art date
Application number
IT09574/77A
Other languages
English (en)
Inventor
Alessandro Renzi Bartolini
Galli Giovanni
Malmberg Alessandro
Petra Atello
Rosalia Bartolini
Original Assignee
Univ Firenze
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Firenze filed Critical Univ Firenze
Priority to IT09574/77A priority Critical patent/IT1109003B/it
Priority to AR273611A priority patent/AR222311A1/es
Priority to DE19782839279 priority patent/DE2839279A1/de
Priority to GB7837048A priority patent/GB2005259B/en
Priority to CA311,555A priority patent/CA1125657A/en
Priority to JP11470178A priority patent/JPS54112897A/ja
Priority to FR7826975A priority patent/FR2434167A1/fr
Priority to CA000399054A priority patent/CA1137489A/en
Application granted granted Critical
Publication of IT1109003B publication Critical patent/IT1109003B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT09574/77A 1977-09-20 1977-09-20 Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo IT1109003B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT09574/77A IT1109003B (it) 1977-09-20 1977-09-20 Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo
AR273611A AR222311A1 (es) 1977-09-20 1978-09-07 Procedimiento para preparar derivados de 1,2,3,3 alpha,8,8 alpha,hexahidropirrol-(2,3-b)indol y sus sales
DE19782839279 DE2839279A1 (de) 1977-09-20 1978-09-09 Derivate des 1,2,3,3a,8,8a-hexahydropyrrolo eckige klammer auf 2,3-b eckige klammer zu indols, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel
GB7837048A GB2005259B (en) 1977-09-20 1978-09-15 Hexahydropyrrolo indole derivatives
CA311,555A CA1125657A (en) 1977-09-20 1978-09-19 Derivatives of 1,2,3,3a,8,8a-hexadydropyrrolo ¬2,3-b| indole
JP11470178A JPS54112897A (en) 1977-09-20 1978-09-20 1*2*3*3a*8*8aahexahydropyrrolo*2*33b*indole derivative*its manufacture and analgesic composition containing it
FR7826975A FR2434167A1 (fr) 1977-09-20 1978-09-20 Derives de l'hexahydro-1,2,3,3a,8,8a pyrrolo indole (2,3,-b)
CA000399054A CA1137489A (en) 1977-09-20 1982-03-22 Derivatives of 1,2,3,3a,8,8a-hexadydropyrrolo (2,3-b) indole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT09574/77A IT1109003B (it) 1977-09-20 1977-09-20 Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo

Publications (1)

Publication Number Publication Date
IT1109003B true IT1109003B (it) 1985-12-16

Family

ID=11132370

Family Applications (1)

Application Number Title Priority Date Filing Date
IT09574/77A IT1109003B (it) 1977-09-20 1977-09-20 Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo

Country Status (7)

Country Link
JP (1) JPS54112897A (it)
AR (1) AR222311A1 (it)
CA (1) CA1125657A (it)
DE (1) DE2839279A1 (it)
FR (1) FR2434167A1 (it)
GB (1) GB2005259B (it)
IT (1) IT1109003B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
GB8616089D0 (en) * 1986-07-02 1986-08-06 Univ Manchester Organic compounds
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina
AT400331B (de) * 1987-05-15 1995-12-27 Hoechst Roussel Pharma 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo (2,3-b)indole, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5260452A (en) * 1989-11-03 1993-11-09 Hoechst-Roussel Pharmaceuticals Inc. 4- and 6-carbamates related to physostigmine and intermediates for the preparation thereof
US5206260A (en) * 1991-11-07 1993-04-27 Merck & Co., Inc. Hexahydropyrrolo[2,3-b]indole derivatives
GB9205670D0 (en) * 1992-03-16 1992-04-29 Indena Spa New derivatives of physostigmine,their use and pharmaceutical formulations containing them
KR20010015714A (ko) * 1997-10-10 2001-02-26 파올로 키에시 선택적인 뇌 항콜린에스테라제활성을 가진 게네세롤린의아미노카보닐추출물의 제조방법
US6495700B1 (en) * 2002-01-09 2002-12-17 Axonyx, Inc. Process for producing phenserine and its analog

Also Published As

Publication number Publication date
FR2434167A1 (fr) 1980-03-21
AR222311A1 (es) 1981-05-15
GB2005259A (en) 1979-04-19
CA1125657A (en) 1982-06-15
DE2839279A1 (de) 1979-03-29
JPS54112897A (en) 1979-09-04
GB2005259B (en) 1982-06-23
FR2434167B1 (it) 1983-03-18

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