DE3883434D1 - Mitomycinanaloge, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen. - Google Patents

Mitomycinanaloge, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen.

Info

Publication number
DE3883434D1
DE3883434D1 DE88109275T DE3883434T DE3883434D1 DE 3883434 D1 DE3883434 D1 DE 3883434D1 DE 88109275 T DE88109275 T DE 88109275T DE 3883434 T DE3883434 T DE 3883434T DE 3883434 D1 DE3883434 D1 DE 3883434D1
Authority
DE
Germany
Prior art keywords
analogs
mitomycin
processes
preparation
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88109275T
Other languages
English (en)
Other versions
DE3883434T2 (de
Inventor
Takushi Kaneko
Henry S L Wong
Terrence W Doyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE3883434D1 publication Critical patent/DE3883434D1/de
Publication of DE3883434T2 publication Critical patent/DE3883434T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
DE88109275T 1987-06-12 1988-06-10 Mitomycinanaloge, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen. Expired - Fee Related DE3883434T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6183987A 1987-06-12 1987-06-12

Publications (2)

Publication Number Publication Date
DE3883434D1 true DE3883434D1 (de) 1993-09-30
DE3883434T2 DE3883434T2 (de) 1993-12-09

Family

ID=22038465

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88109275T Expired - Fee Related DE3883434T2 (de) 1987-06-12 1988-06-10 Mitomycinanaloge, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen.

Country Status (10)

Country Link
US (1) US5374739A (de)
EP (1) EP0294828B1 (de)
JP (1) JPS63316781A (de)
AT (1) ATE93524T1 (de)
CA (1) CA1326487C (de)
CY (1) CY1742A (de)
DE (1) DE3883434T2 (de)
ES (1) ES2058182T3 (de)
HK (1) HK127993A (de)
IL (1) IL86665A0 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524812B1 (en) 1993-10-07 2003-02-25 Regents Of The University Of Minnesota Genes encoding resistance to DNA alkylating agents
US6495348B1 (en) * 1993-10-07 2002-12-17 Regents Of The University Of Minnesota Mitomycin biosynthetic gene cluster
JP2006500996A (ja) 2002-09-26 2006-01-12 エンドバスキュラー デバイセス インコーポレイテッド 溶出性生体適合性移植可能医療器具を介してマイトマイシンを送達するための装置および方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129868C (de) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4460599A (en) * 1979-12-05 1984-07-17 University Patents, Inc. Mitomycin analogs
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4567256A (en) * 1983-05-09 1986-01-28 Bristol-Myers Company Amidine process
US4579737A (en) * 1983-05-09 1986-04-01 Bristol-Myers Company Bis-amidines
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
FR2571373A1 (fr) * 1984-10-09 1986-04-11 Bristol Myers Co Procede de preparation de derives n7-substitues de la mitomycine c

Also Published As

Publication number Publication date
US5374739A (en) 1994-12-20
EP0294828A3 (en) 1990-05-09
IL86665A0 (en) 1988-11-30
DE3883434T2 (de) 1993-12-09
HK127993A (en) 1993-11-26
CA1326487C (en) 1994-01-25
EP0294828B1 (de) 1993-08-25
EP0294828A2 (de) 1988-12-14
CY1742A (en) 1995-10-20
JPH0563476B2 (de) 1993-09-10
JPS63316781A (ja) 1988-12-26
ATE93524T1 (de) 1993-09-15
ES2058182T3 (es) 1994-11-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee