ATE47593T1 - Spiro(benzofuran-2(3h), 1'-cycloheptane>, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents

Spiro(benzofuran-2(3h), 1'-cycloheptane>, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.

Info

Publication number
ATE47593T1
ATE47593T1 AT86111867T AT86111867T ATE47593T1 AT E47593 T1 ATE47593 T1 AT E47593T1 AT 86111867 T AT86111867 T AT 86111867T AT 86111867 T AT86111867 T AT 86111867T AT E47593 T1 ATE47593 T1 AT E47593T1
Authority
AT
Austria
Prior art keywords
sub
products
loweralkyl
cycloheptane
benzofuran
Prior art date
Application number
AT86111867T
Other languages
English (en)
Inventor
Edward J Glamkowski
Frederick J Ehrgott Jr
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of ATE47593T1 publication Critical patent/ATE47593T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Fats And Perfumes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT86111867T 1985-09-05 1986-08-27 Spiro(benzofuran-2(3h), 1'-cycloheptane>, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel. ATE47593T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/772,974 US4623657A (en) 1985-09-05 1985-09-05 Spiro [benzofuran-2(3H),1'-cycloheptane]s and their therapeutic use
EP86111867A EP0217135B1 (de) 1985-09-05 1986-08-27 Spiro[benzofuran-2(3H), 1'-cycloheptane], Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ATE47593T1 true ATE47593T1 (de) 1989-11-15

Family

ID=25096782

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86111867T ATE47593T1 (de) 1985-09-05 1986-08-27 Spiro(benzofuran-2(3h), 1'-cycloheptane>, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.

Country Status (15)

Country Link
US (1) US4623657A (de)
EP (1) EP0217135B1 (de)
JP (1) JPS6263580A (de)
KR (1) KR870003085A (de)
AT (1) ATE47593T1 (de)
AU (1) AU6234486A (de)
CA (1) CA1261341A (de)
DE (1) DE3666588D1 (de)
DK (1) DK423186A (de)
ES (1) ES2001646A6 (de)
GR (1) GR862254B (de)
HU (1) HUT44769A (de)
IL (1) IL79928A (de)
PT (1) PT83307B (de)
ZA (1) ZA866714B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910323A (en) * 1981-10-19 1990-03-20 Hoechst Roussel Pharmaceuticals, Inc. 2'-substituted-spiro(benzofuran-2(3H),1'-cyclohexanes) and intermediates thereof
US5366986A (en) * 1988-04-15 1994-11-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
JP2008292083A (ja) * 2007-05-25 2008-12-04 Denso Corp 冷媒蒸発器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE431085B (sv) * 1977-09-13 1984-01-16 Pfizer 3-(2-hydroxi-4-(substituerade)fenyl)cykloalkanoner och -cykloalkanoder och vissa derivat derav till anvendning for farmakologiska och medicinska endamal
US4404221A (en) 1981-10-19 1983-09-13 Hoechst-Roussel Pharmaceuticals Inc. 2'-Substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and its pharmaceutical use
US4517311A (en) 1981-10-19 1985-05-14 Hoechst-Roussel Pharmaceuticals Inc. 2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and their analgesic and anti-depressant compositions

Also Published As

Publication number Publication date
US4623657A (en) 1986-11-18
DK423186A (da) 1987-03-06
CA1272214C (de) 1990-07-31
AU6234486A (en) 1987-03-12
DK423186D0 (da) 1986-09-04
PT83307A (en) 1986-10-01
CA1261341A (en) 1989-09-26
ZA866714B (en) 1987-04-29
HUT44769A (en) 1988-04-28
GR862254B (en) 1986-12-30
IL79928A0 (en) 1986-12-31
PT83307B (en) 1988-10-07
ES2001646A6 (es) 1988-06-01
KR870003085A (ko) 1987-04-15
EP0217135B1 (de) 1989-10-25
DE3666588D1 (en) 1989-11-30
JPS6263580A (ja) 1987-03-20
EP0217135A1 (de) 1987-04-08
IL79928A (en) 1991-06-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee